CA1220740A - Produit de nettoyage contenant un enzyme, utilisation et preparation - Google Patents

Produit de nettoyage contenant un enzyme, utilisation et preparation

Info

Publication number: CA1220740A
Authority: CA; Canada
Prior art keywords: enzyme; enzymes; contaminants; enzyme composition; composition
Prior art date: 1982-10-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA000439619A

Other languages

English (en)

Inventor

Jan G. Vincent

Viggo Mohr

Lars G.I. Hellgren

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

ANTARCTIC PHARMA AB

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-10-25

Filing date

1983-10-25

Publication date

1987-04-21

1982-10-25 Priority claimed from SE8206022A external-priority patent/SE8206022D0/xx

1983-04-22 Priority claimed from SE8302268A external-priority patent/SE8302268L/

1983-10-25 Application filed by Individual filed Critical Individual

1987-04-21 Application granted granted Critical

1987-04-21 Publication of CA1220740A publication Critical patent/CA1220740A/fr

Status Expired legal-status Critical Current

Links

102000004190 Enzymes Human genes 0.000 title claims abstract description 151
108090000790 Enzymes Proteins 0.000 title claims abstract description 151
239000000203 mixture Substances 0.000 title claims abstract description 103
238000002360 preparation method Methods 0.000 title claims abstract description 37
238000004140 cleaning Methods 0.000 title abstract description 20
239000000356 contaminant Substances 0.000 claims abstract description 29
241001465754 Metazoa Species 0.000 claims abstract description 28
238000000034 method Methods 0.000 claims abstract description 23
241000251468 Actinopterygii Species 0.000 claims abstract description 10
229930184510 Mallotus Natural products 0.000 claims abstract description 10
241001060384 Mallotus <angiosperm> Species 0.000 claims abstract description 10
230000001225 therapeutic effect Effects 0.000 claims abstract description 10
229940088598 enzyme Drugs 0.000 claims description 146
241001417902 Mallotus villosus Species 0.000 claims description 25
239000000126 substance Substances 0.000 claims description 15
150000002632 lipids Chemical class 0.000 claims description 13
239000000654 additive Substances 0.000 claims description 7
239000000758 substrate Substances 0.000 claims description 7
239000007857 degradation product Substances 0.000 claims description 6
239000000843 powder Substances 0.000 claims description 6
102000004169 proteins and genes Human genes 0.000 claims description 6
108090000623 proteins and genes Proteins 0.000 claims description 6
239000004094 surface-active agent Substances 0.000 claims description 6
102000057297 Pepsin A Human genes 0.000 claims description 5
108090000284 Pepsin A Proteins 0.000 claims description 5
150000004676 glycans Polymers 0.000 claims description 5
102000039446 nucleic acids Human genes 0.000 claims description 5
108020004707 nucleic acids Proteins 0.000 claims description 5
150000007523 nucleic acids Chemical class 0.000 claims description 5
229940111202 pepsin Drugs 0.000 claims description 5
239000005017 polysaccharide Substances 0.000 claims description 5
102000004196 processed proteins & peptides Human genes 0.000 claims description 5
108090000765 processed proteins & peptides Proteins 0.000 claims description 5
229920002683 Glycosaminoglycan Polymers 0.000 claims description 4
-1 bandages Substances 0.000 claims description 4
239000012459 cleaning agent Substances 0.000 claims description 4
239000000499 gel Substances 0.000 claims description 4
150000003904 phospholipids Chemical class 0.000 claims description 4
229920001282 polysaccharide Polymers 0.000 claims description 4
239000004753 textile Substances 0.000 claims description 4
239000006071 cream Substances 0.000 claims description 3
239000000865 liniment Substances 0.000 claims description 3
239000003921 oil Substances 0.000 claims description 3
239000002674 ointment Substances 0.000 claims description 3
239000007921 spray Substances 0.000 claims description 3
239000006188 syrup Substances 0.000 claims description 3
235000020357 syrup Nutrition 0.000 claims description 3
230000000996 additive effect Effects 0.000 claims description 2
238000004900 laundering Methods 0.000 claims description 2
239000006072 paste Substances 0.000 claims description 2
239000003826 tablet Substances 0.000 claims description 2
229920001577 copolymer Chemical class 0.000 claims 1
150000004804 polysaccharides Polymers 0.000 claims 1
239000000047 product Substances 0.000 claims 1
239000000463 material Substances 0.000 abstract description 18
241000239366 Euphausiacea Species 0.000 description 29
230000000694 effects Effects 0.000 description 20
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 20
239000004365 Protease Substances 0.000 description 17
230000001338 necrotic effect Effects 0.000 description 14
108010056079 Subtilisins Proteins 0.000 description 13
102000005158 Subtilisins Human genes 0.000 description 13
239000008280 blood Substances 0.000 description 13
210000004369 blood Anatomy 0.000 description 12
239000000284 extract Substances 0.000 description 12
239000004744 fabric Substances 0.000 description 12
238000012360 testing method Methods 0.000 description 11
102000009123 Fibrin Human genes 0.000 description 10
108010073385 Fibrin Proteins 0.000 description 10
230000015556 catabolic process Effects 0.000 description 10
BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 9
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 9
238000006731 degradation reaction Methods 0.000 description 9
229950003499 fibrin Drugs 0.000 description 9
239000011780 sodium chloride Substances 0.000 description 9
239000000243 solution Substances 0.000 description 9
108010086613 Streptodornase and Streptokinase Proteins 0.000 description 8
239000003599 detergent Substances 0.000 description 8
239000006228 supernatant Substances 0.000 description 8
238000005406 washing Methods 0.000 description 8
102000004142 Trypsin Human genes 0.000 description 7
108090000631 Trypsin Proteins 0.000 description 7
206010052428 Wound Diseases 0.000 description 7
208000027418 Wounds and injury Diseases 0.000 description 7
239000000306 component Substances 0.000 description 7
229940055729 papain Drugs 0.000 description 7
108090000526 Papain Proteins 0.000 description 6
102000035195 Peptidases Human genes 0.000 description 6
108091005804 Peptidases Proteins 0.000 description 6
235000019834 papain Nutrition 0.000 description 6
108090000270 Ficain Proteins 0.000 description 5
230000000593 degrading effect Effects 0.000 description 5
239000008367 deionised water Substances 0.000 description 5
229910021641 deionized water Inorganic materials 0.000 description 5
238000000605 extraction Methods 0.000 description 5
235000019836 ficin Nutrition 0.000 description 5
POTUGHMKJGOKRI-UHFFFAOYSA-N ficin Chemical compound FI=CI=N POTUGHMKJGOKRI-UHFFFAOYSA-N 0.000 description 5
230000002797 proteolythic effect Effects 0.000 description 5
238000001804 debridement Methods 0.000 description 4
230000002255 enzymatic effect Effects 0.000 description 4
230000007935 neutral effect Effects 0.000 description 4
235000018102 proteins Nutrition 0.000 description 4
241000894007 species Species 0.000 description 4
VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 description 4
235000004391 Chenopodium capitatum Nutrition 0.000 description 3
244000038022 Chenopodium capitatum Species 0.000 description 3
241000239370 Euphausia superba Species 0.000 description 3
239000000969 carrier Substances 0.000 description 3
229940079919 digestives enzyme preparation Drugs 0.000 description 3
235000013336 milk Nutrition 0.000 description 3
239000008267 milk Substances 0.000 description 3
210000004080 milk Anatomy 0.000 description 3
235000019419 proteases Nutrition 0.000 description 3
238000000746 purification Methods 0.000 description 3
235000019890 Amylum Nutrition 0.000 description 2
241000283690 Bos taurus Species 0.000 description 2
LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 2
108090001060 Lipase Proteins 0.000 description 2
102000004882 Lipase Human genes 0.000 description 2
239000004367 Lipase Substances 0.000 description 2
241000124008 Mammalia Species 0.000 description 2
206010039509 Scab Diseases 0.000 description 2
229920002472 Starch Polymers 0.000 description 2
239000002253 acid Substances 0.000 description 2
230000002411 adverse Effects 0.000 description 2
125000000129 anionic group Chemical group 0.000 description 2
239000007864 aqueous solution Substances 0.000 description 2
VSGNNIFQASZAOI-UHFFFAOYSA-L calcium acetate Chemical compound [Ca+2].CC([O-])=O.CC([O-])=O VSGNNIFQASZAOI-UHFFFAOYSA-L 0.000 description 2
239000001639 calcium acetate Substances 0.000 description 2
235000011092 calcium acetate Nutrition 0.000 description 2
229960005147 calcium acetate Drugs 0.000 description 2
239000005018 casein Substances 0.000 description 2
BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 2
235000021240 caseins Nutrition 0.000 description 2
125000002091 cationic group Chemical group 0.000 description 2
230000001079 digestive effect Effects 0.000 description 2
239000012153 distilled water Substances 0.000 description 2
238000002474 experimental method Methods 0.000 description 2
210000001035 gastrointestinal tract Anatomy 0.000 description 2
238000005227 gel permeation chromatography Methods 0.000 description 2
230000036074 healthy skin Effects 0.000 description 2
210000000936 intestine Anatomy 0.000 description 2
JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
235000019421 lipase Nutrition 0.000 description 2
229960003511 macrogol Drugs 0.000 description 2
238000002156 mixing Methods 0.000 description 2
229920001184 polypeptide Polymers 0.000 description 2
235000019833 protease Nutrition 0.000 description 2
239000002904 solvent Substances 0.000 description 2
229960004533 streptodornase Drugs 0.000 description 2
239000012588 trypsin Substances 0.000 description 2
238000003809 water extraction Methods 0.000 description 2
QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 1
102000013142 Amylases Human genes 0.000 description 1
108010065511 Amylases Proteins 0.000 description 1
241000193830 Bacillus <bacterium> Species 0.000 description 1
244000063299 Bacillus subtilis Species 0.000 description 1
235000014469 Bacillus subtilis Nutrition 0.000 description 1
102000008186 Collagen Human genes 0.000 description 1
108010035532 Collagen Proteins 0.000 description 1
229920000742 Cotton Polymers 0.000 description 1
XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 description 1
108020004414 DNA Proteins 0.000 description 1
102000053602 DNA Human genes 0.000 description 1
108010008532 Deoxyribonuclease I Proteins 0.000 description 1
102000007260 Deoxyribonuclease I Human genes 0.000 description 1
108010053770 Deoxyribonucleases Proteins 0.000 description 1
102000016911 Deoxyribonucleases Human genes 0.000 description 1
229920002307 Dextran Polymers 0.000 description 1
102000005593 Endopeptidases Human genes 0.000 description 1
108010059378 Endopeptidases Proteins 0.000 description 1
108090000371 Esterases Proteins 0.000 description 1
241000212918 Euphausia crystallorophias Species 0.000 description 1
102000018389 Exopeptidases Human genes 0.000 description 1
108010091443 Exopeptidases Proteins 0.000 description 1
108010088842 Fibrinolysin Proteins 0.000 description 1
102000001554 Hemoglobins Human genes 0.000 description 1
108010054147 Hemoglobins Proteins 0.000 description 1
206010061218 Inflammation Diseases 0.000 description 1
OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 1
229920006063 Lamide® Polymers 0.000 description 1
241000212925 Meganyctiphanes norvegica Species 0.000 description 1
206010067482 No adverse event Diseases 0.000 description 1
101710163270 Nuclease Proteins 0.000 description 1
108010071195 Nucleotidases Proteins 0.000 description 1
102000007533 Nucleotidases Human genes 0.000 description 1
206010034759 Petit mal epilepsy Diseases 0.000 description 1
108010064785 Phospholipases Proteins 0.000 description 1
102000015439 Phospholipases Human genes 0.000 description 1
108700019535 Phosphoprotein Phosphatases Proteins 0.000 description 1
102000045595 Phosphoprotein Phosphatases Human genes 0.000 description 1
239000002202 Polyethylene glycol Substances 0.000 description 1
206010039792 Seborrhoea Diseases 0.000 description 1
229920005654 Sephadex Polymers 0.000 description 1
239000012507 Sephadex™ Substances 0.000 description 1
108010023197 Streptokinase Proteins 0.000 description 1
108090000787 Subtilisin Proteins 0.000 description 1
ULUAUXLGCMPNKK-UHFFFAOYSA-N Sulfobutanedioic acid Chemical compound OC(=O)CC(C(O)=O)S(O)(=O)=O ULUAUXLGCMPNKK-UHFFFAOYSA-N 0.000 description 1
208000025865 Ulcer Diseases 0.000 description 1
238000010521 absorption reaction Methods 0.000 description 1
230000002378 acidificating effect Effects 0.000 description 1
239000004480 active ingredient Substances 0.000 description 1
239000000853 adhesive Substances 0.000 description 1
230000001070 adhesive effect Effects 0.000 description 1
238000001042 affinity chromatography Methods 0.000 description 1
238000004220 aggregation Methods 0.000 description 1
230000002776 aggregation Effects 0.000 description 1
235000019418 amylase Nutrition 0.000 description 1
229940025131 amylases Drugs 0.000 description 1
238000004458 analytical method Methods 0.000 description 1
239000004599 antimicrobial Substances 0.000 description 1
239000008365 aqueous carrier Substances 0.000 description 1
239000012736 aqueous medium Substances 0.000 description 1
230000002358 autolytic effect Effects 0.000 description 1
230000005540 biological transmission Effects 0.000 description 1
229920001222 biopolymer Polymers 0.000 description 1
150000001720 carbohydrates Chemical class 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
235000019365 chlortetracycline Nutrition 0.000 description 1
229920001436 collagen Polymers 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
239000000470 constituent Substances 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
238000010790 dilution Methods 0.000 description 1
239000012895 dilution Substances 0.000 description 1
239000003937 drug carrier Substances 0.000 description 1
210000005069 ears Anatomy 0.000 description 1
230000001909 effect on DNA Effects 0.000 description 1
230000000678 effect on lipid Effects 0.000 description 1
238000010828 elution Methods 0.000 description 1
239000003995 emulsifying agent Substances 0.000 description 1
229940066758 endopeptidases Drugs 0.000 description 1
210000000416 exudates and transudate Anatomy 0.000 description 1
229940001501 fibrinolysin Drugs 0.000 description 1
230000003480 fibrinolytic effect Effects 0.000 description 1
239000012847 fine chemical Substances 0.000 description 1
235000013305 food Nutrition 0.000 description 1
210000005224 forefinger Anatomy 0.000 description 1
239000011521 glass Substances 0.000 description 1
210000004247 hand Anatomy 0.000 description 1
238000000265 homogenisation Methods 0.000 description 1
238000001727 in vivo Methods 0.000 description 1
230000004054 inflammatory process Effects 0.000 description 1
239000003112 inhibitor Substances 0.000 description 1
238000002347 injection Methods 0.000 description 1
239000007924 injection Substances 0.000 description 1
238000004255 ion exchange chromatography Methods 0.000 description 1
239000004310 lactic acid Substances 0.000 description 1
235000014655 lactic acid Nutrition 0.000 description 1
239000010985 leather Substances 0.000 description 1
229940040145 liniment Drugs 0.000 description 1
239000007788 liquid Substances 0.000 description 1
239000012528 membrane Substances 0.000 description 1
229910052751 metal Inorganic materials 0.000 description 1
239000002184 metal Substances 0.000 description 1
150000002739 metals Chemical class 0.000 description 1
230000000813 microbial effect Effects 0.000 description 1
238000010422 painting Methods 0.000 description 1
210000000496 pancreas Anatomy 0.000 description 1
239000002304 perfume Substances 0.000 description 1
230000000704 physical effect Effects 0.000 description 1
108010016297 plasmin drug combination deoxyribonuclease Proteins 0.000 description 1
239000011505 plaster Substances 0.000 description 1
239000004033 plastic Substances 0.000 description 1
229920003023 plastic Polymers 0.000 description 1
229920001223 polyethylene glycol Polymers 0.000 description 1
229910052573 porcelain Inorganic materials 0.000 description 1
239000012266 salt solution Substances 0.000 description 1
229940071089 sarcosinate Drugs 0.000 description 1
239000013049 sediment Substances 0.000 description 1
229920002545 silicone oil Polymers 0.000 description 1
208000017520 skin disease Diseases 0.000 description 1
239000007787 solid Substances 0.000 description 1
238000011146 sterile filtration Methods 0.000 description 1
230000001954 sterilising effect Effects 0.000 description 1
238000004659 sterilization and disinfection Methods 0.000 description 1
238000003860 storage Methods 0.000 description 1
229960005202 streptokinase Drugs 0.000 description 1
208000024891 symptom Diseases 0.000 description 1
229920002994 synthetic fiber Polymers 0.000 description 1
239000008399 tap water Substances 0.000 description 1
235000020679 tap water Nutrition 0.000 description 1
230000001810 trypsinlike Effects 0.000 description 1
OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
231100000397 ulcer Toxicity 0.000 description 1
210000003932 urinary bladder Anatomy 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/814—Enzyme separation or purification

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oil, Petroleum & Natural Gas (AREA)
Molecular Biology (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Biotechnology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Dermatology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Detergent Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)
Cosmetics (AREA)

CA000439619A 1982-10-25 1983-10-25 Produit de nettoyage contenant un enzyme, utilisation et preparation Expired CA1220740A (fr)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
SE8206022A SE8206022D0 (sv)	1982-10-25	1982-10-25	Nedbrytning av nekrotisk vevnad, fibrin, pus, purulent exudat, blodkoagler medelst enzymer fran fisk (lodde), skaldjur (krill), vexter (papain,ficin) samt alcalase och pancreatin
SE8206022-9		1983-04-22
SE8302268A SE8302268L (sv)	1983-04-22	1983-04-22	Ny kombination av proteolytiska och lipolytiska enzymer lemplig som tvettkomposition
SE8302268-1		1983-04-22

Publications (1)

Publication Number	Publication Date
CA1220740A true CA1220740A (fr)	1987-04-21

Family

ID=26658270

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA000439619A Expired CA1220740A (fr)	1982-10-25	1983-10-25	Produit de nettoyage contenant un enzyme, utilisation et preparation

Country Status (9)

Country	Link
US (1)	US4963491A (fr)
EP (1)	EP0107634B1 (fr)
JP (2)	JPS59501908A (fr)
AU (1)	AU573730B2 (fr)
CA (1)	CA1220740A (fr)
DE (1)	DE3379589D1 (fr)
DK (1)	DK166566B1 (fr)
FI (1)	FI80598C (fr)
WO (1)	WO1984001715A1 (fr)

Families Citing this family (104)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE454566B (sv) *	1984-04-24	1988-05-16	Lars G I Hellgren	Farmaceutisk komposition innehallande en verksam mengd av vattenlosliga proteinaser som extraherats fran ett vattenlevande djur valt av ordningen euphausiaceae eller slektet mallotus
JPS6130527A (ja) *	1984-07-20	1986-02-12	Kao Corp	血栓溶解剤
SE8703064D0 (sv) *	1987-08-06	1987-08-06	Viggo Mohr	Method for isolating active enzyme preparations from animal tissues
SE8801701D0 (sv) *	1988-05-05	1988-05-05	Pharmacia Ab	Production technology based on enzymic method
NO164844C (no) *	1988-10-24	1990-11-21	Norsk Hydro As	Fremgangsmaate ved utvinning av enzymer fra krepsdyr.
US5258304A (en) *	1989-10-27	1993-11-02	Genencor International, Inc.	Method of removing microorganisms from surfaces with Type II endoglycosidase
US5238843A (en) *	1989-10-27	1993-08-24	Genencor International, Inc.	Method for cleaning a surface on which is bound a glycoside-containing substance
GB2248858B (en) *	1990-10-17	1994-04-27	Metra Oy Ab	Vacuum toilet system with treated rinse liquid
JPH06508835A (ja) *	1991-06-24	1994-10-06	キャリングタン、ラバラトーリズ、インコーパレイティド	外傷清浄剤
US5945102A (en) *	1994-11-22	1999-08-31	Phairson Medical Inc.	Crustacean and fish derived multifunctional enzyme
US7947270B2 (en) *	1992-05-22	2011-05-24	Arcimboldo Ab	Removing dental plaque with krill enzymes
SE9201628D0 (sv) *	1992-05-22	1992-05-22	Phairson Medical Ab	Pharmaceutical composition
US20060134641A1 (en) *	1992-05-22	2006-06-22	Franklin Richard L	Treating viral infections with krill enzymes
US6030612A (en) *	1994-11-22	2000-02-29	Phairson Medical Inc.	Antimicrobial uses of multifunctional enzyme
US5958406A (en) *	1994-11-22	1999-09-28	Phairson Medical Inc.	Acne treatment with multifunctional enzyme
JPH0776700A (ja) *	1993-07-14	1995-03-20	Senju Pharmaceut Co Ltd	コンタクトレンズ用剤の安定化方法
SE9303899D0 (sv) *	1993-11-22	1993-11-22	Phairson Medical Inc	Läkemedel
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- 1983-10-24 JP JP58503493A patent/JPS59501908A/ja active Granted
- 1983-10-24 DE DE8383850279T patent/DE3379589D1/de not_active Expired
- 1983-10-24 EP EP83850279A patent/EP0107634B1/fr not_active Expired
- 1983-10-25 CA CA000439619A patent/CA1220740A/fr not_active Expired
1984
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- 1984-06-25 FI FI842555A patent/FI80598C/fi not_active IP Right Cessation
1989
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1992
- 1992-09-03 JP JP4236141A patent/JPH0662994B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DK166566B1 (da)	1993-06-14
DE3379589D1 (en)	1989-05-18
DK308684A (da)	1984-06-22
WO1984001715A1 (fr)	1984-05-10
EP0107634A2 (fr)	1984-05-02
JPS59501908A (ja)	1984-11-15
EP0107634A3 (en)	1986-10-08
AU2204183A (en)	1984-05-22
EP0107634B1 (fr)	1989-04-12
DK308684D0 (da)	1984-06-22
JPH0662994B2 (ja)	1994-08-17
JPH05262665A (ja)	1993-10-12
US4963491A (en)	1990-10-16
FI842555L (fi)	1984-06-25
FI80598B (fi)	1990-03-30
JPH0517209B2 (fr)	1993-03-08
FI842555A0 (fi)	1984-06-25
AU573730B2 (en)	1988-06-23
FI80598C (fi)	1990-07-10

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Date	Code	Title	Description
2004-04-21	MKEX	Expiry

Publication	Publication Date	Title
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RU2099090C1 (ru)	1997-12-20	Способ очистки хирургических инструментов
Shtacher	1969	Selective renal involvement in the early development of hypercalcemia and hypophosphatemia in VX-2 carcinoma-bearing rabbits: Studies on serum and tissues alkaline phosphatase and renal handling of phosphorus
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