CA1289075C - Produit pharmaceutique - Google Patents

Produit pharmaceutique

Info

Publication number
CA1289075C
CA1289075C CA000523051A CA523051A CA1289075C CA 1289075 C CA1289075 C CA 1289075C CA 000523051 A CA000523051 A CA 000523051A CA 523051 A CA523051 A CA 523051A CA 1289075 C CA1289075 C CA 1289075C
Authority
CA
Canada
Prior art keywords
composition
weight
ethyl cellulose
wax
fatty acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000523051A
Other languages
English (en)
Inventor
Navnit H. Shah
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25175361&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA1289075(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA1289075C publication Critical patent/CA1289075C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
CA000523051A 1985-11-18 1986-11-14 Produit pharmaceutique Expired - Lifetime CA1289075C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/799,229 US4892742A (en) 1985-11-18 1985-11-18 Controlled release compositions with zero order release
US799,229 1985-11-18

Publications (1)

Publication Number Publication Date
CA1289075C true CA1289075C (fr) 1991-09-17

Family

ID=25175361

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000523051A Expired - Lifetime CA1289075C (fr) 1985-11-18 1986-11-14 Produit pharmaceutique

Country Status (16)

Country Link
US (1) US4892742A (fr)
EP (1) EP0224146B1 (fr)
JP (1) JPS62120316A (fr)
CN (1) CN86107734A (fr)
AU (1) AU594392B2 (fr)
CA (1) CA1289075C (fr)
DE (1) DE3685094D1 (fr)
DK (1) DK546886A (fr)
GR (1) GR862727B (fr)
HU (1) HU200683B (fr)
IL (1) IL80643A0 (fr)
MC (1) MC1782A1 (fr)
NZ (1) NZ218297A (fr)
PH (1) PH23292A (fr)
PT (1) PT83756B (fr)
ZA (1) ZA868249B (fr)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2585246A1 (fr) * 1985-07-26 1987-01-30 Cortial Procede d'obtention de formes pharmaceutiques solides a liberation prolongee
SE8505034D0 (sv) * 1985-10-25 1985-10-25 Haessle Ab Kropp bestaende av en kerna med ett overdrag
EP0325086A3 (fr) * 1987-11-23 1990-10-31 Jago Research Ag Méthodes pour obtenir des systèmes thérapeutiques à libération contrôlée du médicament
IE60383B1 (en) * 1988-05-27 1994-07-13 Elan Corp Plc Controlled release pharmaceutical formulation
GB8813064D0 (en) * 1988-06-02 1988-07-06 Euro Celtique Sa Controlled release dosage forms having defined water content
US5612059A (en) * 1988-08-30 1997-03-18 Pfizer Inc. Use of asymmetric membranes in delivery devices
IT1237904B (it) * 1989-12-14 1993-06-18 Ubaldo Conte Compresse a rilascio a velocita' controllata delle sostanze attive
ATE118345T1 (de) * 1990-08-07 1995-03-15 Pfizer Verwendung von interfacial polymerisierten membranen in abgabevorrichtungen.
ES2106818T3 (es) * 1991-10-30 1997-11-16 Glaxo Group Ltd Composicion multicapa que contiene antagonistas de histamina o secotina.
US5407686A (en) * 1991-11-27 1995-04-18 Sidmak Laboratories, Inc. Sustained release composition for oral administration of active ingredient
US5160742A (en) * 1991-12-31 1992-11-03 Abbott Laboratories System for delivering an active substance for sustained release
US5656296A (en) * 1992-04-29 1997-08-12 Warner-Lambert Company Dual control sustained release drug delivery systems and methods for preparing same
GB9325445D0 (en) 1993-12-13 1994-02-16 Cortecs Ltd Pharmaceutical formulations
AU1806895A (en) * 1994-02-23 1995-09-11 Bm Research A/S Controlled release composition
US5458887A (en) * 1994-03-02 1995-10-17 Andrx Pharmaceuticals, Inc. Controlled release tablet formulation
US5482718A (en) * 1994-03-23 1996-01-09 Hoffmann-La Roche Inc. Colon-targeted delivery system
JPH08143450A (ja) * 1994-11-14 1996-06-04 Taiyo Yakuhin Kogyo Kk 徐放化製剤
US5773031A (en) * 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
FR2766708B1 (fr) * 1997-07-30 2000-05-05 Galenix Dev Composition contenant de l'hydroxypropylcellulose, de l'hydroxypropylmethylcellulose et/ou de l'ethylcellullose a titre d'agents desintegrants, et procede d'obtention
FR2766707A1 (fr) * 1997-07-30 1999-02-05 Galenix Dev Composition contenant de l'hydroxypropylcellulose, de l'hydroxypropylmethyl-cellulose et/ou de l'ethylcellulose a titre d'agents desintegrants, et procede d'obtention
US6607751B1 (en) * 1997-10-10 2003-08-19 Intellipharamaceutics Corp. Controlled release delivery device for pharmaceutical agents incorporating microbial polysaccharide gum
JP4533531B2 (ja) * 1998-04-03 2010-09-01 ビーエム リサーチ エイ／エス 制御放出組成物
US20060240105A1 (en) * 1998-11-02 2006-10-26 Elan Corporation, Plc Multiparticulate modified release composition
US20090297597A1 (en) * 1998-11-02 2009-12-03 Gary Liversidge Modified Release Ticlopidine Compositions
MXPA01004381A (es) * 1998-11-02 2005-09-08 Elan Corp Plc Composicion de multiparticulado de liberacion modificada.
US20070122481A1 (en) * 1998-11-02 2007-05-31 Elan Corporation Plc Modified Release Compositions Comprising a Fluorocytidine Derivative for the Treatment of Cancer
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
KR100889069B1 (ko) 1999-10-29 2009-03-17 유로-셀티크 소시에떼 아노뉨 서방성 하이드로코돈 제형
DE60123384T2 (de) * 2000-02-04 2007-08-02 DepoMed, Inc., Menlo Park Dosierungsform des typs "hülle und kern" mit einer wirkstofffreisetzung, die sich der nullten ordnung annähert
AU2738302A (en) 2000-10-30 2002-05-15 Euro Celtique Sa Controlled release hydrocodone formulations
US20030070584A1 (en) * 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing cellulose ethers
AU4061702A (en) * 2001-05-15 2003-04-03 Mcneil-Ppc, Inc. Dip coating compositions containing starch or dextrin
EP1429744A1 (fr) * 2001-09-21 2004-06-23 Egalet A/S Systeme a liberation de polymere de morphine
US20040234602A1 (en) 2001-09-21 2004-11-25 Gina Fischer Polymer release system
US8309118B2 (en) * 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
WO2003037244A2 (fr) * 2001-10-29 2003-05-08 Therics, Inc. Systeme d'elaboration de formes pharmaceutiques a liberation controlee, du type forme pharmaceutique a profil de liberation d'ordre zero elaboree en impression tridimensionnelle
US6602911B2 (en) * 2001-11-05 2003-08-05 Cypress Bioscience, Inc. Methods of treating fibromyalgia
US20050163846A1 (en) * 2001-11-21 2005-07-28 Eisai Co., Ltd. Preparation composition containing acid-unstable physiologically active compound, and process for producing same
US20030118647A1 (en) * 2001-12-04 2003-06-26 Pawan Seth Extended release tablet of metformin
CA2470636A1 (fr) * 2001-12-20 2003-07-03 Pharmacia Corporation Formes dosifiees a liberation soutenue d'ordre zero et procede de production associe
CA2479350A1 (fr) * 2002-03-15 2003-09-25 Cypress Bioscience, Inc. Inhibiteurs de recaptage de 5-ht pour le traitement de syndromes de la douleur viscerale
US7429619B2 (en) * 2002-08-02 2008-09-30 Mcneil Consumer Healthcare Polyacrylic film forming compositions
US20080220074A1 (en) * 2002-10-04 2008-09-11 Elan Corporation Plc Gamma radiation sterilized nanoparticulate docetaxel compositions and methods of making same
US20040121010A1 (en) * 2002-10-25 2004-06-24 Collegium Pharmaceutical, Inc. Pulsatile release compositions of milnacipran
US20060003004A1 (en) * 2002-10-25 2006-01-05 Collegium Pharmaceutical, Inc. Pulsatile release compositions of milnacipran
CA2501324A1 (fr) * 2002-10-30 2004-05-21 Pharmacia Corporation Comprimes oraux a liberation etendue et procedes de fabrication et d'utilisation associes
EP1562552A1 (fr) * 2002-11-08 2005-08-17 Egalet A/S Compositions de carvedilol a liberation commandee
WO2004067039A1 (fr) * 2003-01-28 2004-08-12 Collegium Pharmaceutical, Inc. Compositions multiparticulaires de milnacipran destinees a etre administrees par voie orale
ATE454886T1 (de) * 2003-03-26 2010-01-15 Egalet As Matrixzubereitungen für die kontrollierte darreichung von arzneistoffen
WO2004084868A1 (fr) 2003-03-26 2004-10-07 Egalet A/S Systeme de liberation regulee de morphine
US8802139B2 (en) 2003-06-26 2014-08-12 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
NZ549838A (en) * 2004-03-26 2010-04-30 Eisai R&D Man Co Ltd Coated controlled-release preparation containing a gastric acid secretion inhibitor
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US20060024361A1 (en) * 2004-07-28 2006-02-02 Isa Odidi Disintegrant assisted controlled release technology
US10624858B2 (en) * 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
CN100548309C (zh) * 2004-11-24 2009-10-14 东北制药总厂 司他夫定缓释片剂
WO2006063078A2 (fr) * 2004-12-08 2006-06-15 Elan Corporation, Plc Composition pharmaceutique de topiramate
MX2007007836A (es) * 2004-12-27 2007-08-20 Eisai R&D Man Co Ltd Metodo para estabilizar un farmaco anti-demencia.
US20090208579A1 (en) * 2004-12-27 2009-08-20 Eisai R & D Management Co., Ltd. Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same
US20060280789A1 (en) * 2004-12-27 2006-12-14 Eisai Research Institute Sustained release formulations
US20060246003A1 (en) * 2004-12-27 2006-11-02 Eisai Co. Ltd. Composition containing anti-dementia drug
US20070298098A1 (en) * 2005-02-16 2007-12-27 Elan Pharma International Limited Controlled Release Compositions Comprising Levetiracetam
US7829000B2 (en) * 2005-02-25 2010-11-09 Hewlett-Packard Development Company, L.P. Core-shell solid freeform fabrication
AU2006235483B2 (en) * 2005-04-12 2010-11-25 Elan Pharma International Limited Controlled release compositions comprising a cephalosporin for the treatment of a bacterial infection
CA2611081C (fr) * 2005-06-03 2016-05-31 Egalet A/S Systeme d'administration de medicaments permettant d'administrer des substances actives dispersees dans un milieu de dispersion
WO2007037790A2 (fr) * 2005-06-08 2007-04-05 Elan Corporation, Plc Compositions famciclovir à libération modifiée
US7994220B2 (en) * 2005-09-28 2011-08-09 Cypress Bioscience, Inc. Milnacipran for the long-term treatment of fibromyalgia syndrome
US20090148519A1 (en) * 2005-09-29 2009-06-11 Yasuhiro Zaima Pulsed-release preparation having improved disintegration properties in vivo
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
JP5457830B2 (ja) * 2006-04-03 2014-04-02 オディディ，イサ オルガノゾル被膜を含む制御放出送達デバイス
US10960077B2 (en) * 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
US20080081067A1 (en) * 2006-10-03 2008-04-03 Gupta Manishkumar Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof
WO2008062320A2 (fr) * 2006-10-06 2008-05-29 Eisai R&D Management Co., Ltd Formulations à libération prolongée d'un inhibiteur de la pompe à protons
NZ577560A (en) * 2007-01-16 2012-01-12 Egalet Ltd Use of i) a polyglycol and ii) an active drug substance for the preparation of a pharmaceutical composition for i) mitigating the risk of alcohol induced dose dumping and/or ii) reducing the risk of drug abuse
EP2155167A2 (fr) 2007-06-04 2010-02-24 Egalet A/S Compositions pharmaceutiques à libération contrôlée pour un effet prolongé
CA2702935A1 (fr) * 2007-10-19 2009-04-23 Purdue Research Foundation Formulations solides de composes cristallins
NZ594207A (en) 2009-02-06 2013-03-28 Egalet Ltd Immediate release composition resistant to abuse by intake of alcohol
WO2010143202A1 (fr) * 2009-06-09 2010-12-16 Sun Pharmaceutical Industries Ltd. Composition pharmaceutique
NZ597283A (en) 2009-06-24 2013-07-26 Egalet Ltd Controlled release formulations
BR112015000150A2 (pt) 2012-07-06 2017-06-27 Egalet Ltd composições farmacêuticas dissuasoras de abuso de liberação controlada
CA2936740C (fr) 2014-10-31 2017-10-10 Purdue Pharma Methodes et compositions destinees au traitement du trouble de deficit d'attention
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1290661A (fr) * 1960-05-31 1962-04-13 Abbott Lab Méthode d'enrobage de comprimés
US4140756A (en) * 1976-06-10 1979-02-20 Mead Johnson & Company Film-coated matrix core tablet
DD146547A5 (de) * 1978-07-15 1981-02-18 Boehringer Sohn Ingelheim Arzneimittel-retardform mit unloeslichen poroesen diffusionshuellen
US4309406A (en) * 1979-07-10 1982-01-05 American Home Products Corporation Sustained release pharmaceutical compositions
US4252786A (en) * 1979-11-16 1981-02-24 E. R. Squibb & Sons, Inc. Controlled release tablet
FR2506157A1 (fr) * 1981-05-20 1982-11-26 Lipha Preparation pharmaceutique de " naftidrofuryl " a liberation controlee
HU187215B (en) * 1983-01-26 1985-11-28 Egyt Gyogyszervegyeszeti Gyar Method for producing pharmaceutical product of high actor content and prolonged effect
AU581177B2 (en) * 1983-05-31 1989-02-16 Choong-Gook Jang Dry direct compression compositions for controlled release dosage forms
DE3413608A1 (de) * 1984-04-11 1985-10-24 Hoechst Ag, 6230 Frankfurt Implantierbare zubereitungen von regulatorischen peptiden mit gesteuerter freisetzung und verfahren zu ihrer herstellung
GB8521494D0 (en) * 1985-08-29 1985-10-02 Zyma Sa Controlled release tablet

Also Published As

Publication number Publication date
PT83756A (en) 1986-12-01
US4892742A (en) 1990-01-09
DK546886A (da) 1987-05-19
PH23292A (en) 1989-06-30
CN86107734A (zh) 1987-05-20
GR862727B (en) 1987-03-19
EP0224146A3 (en) 1987-09-23
EP0224146B1 (fr) 1992-04-29
JPS62120316A (ja) 1987-06-01
AU594392B2 (en) 1990-03-08
HU200683B (en) 1990-08-28
EP0224146A2 (fr) 1987-06-03
NZ218297A (en) 1990-03-27
MC1782A1 (fr) 1987-09-02
PT83756B (pt) 1989-06-30
IL80643A0 (en) 1987-02-27
AU6532586A (en) 1987-05-21
ZA868249B (en) 1987-06-24
HUT42321A (en) 1987-07-28
DK546886D0 (da) 1986-11-14
DE3685094D1 (de) 1992-06-04

Similar Documents

Publication Publication Date Title
CA1289075C (fr) Produit pharmaceutique
US7410652B2 (en) Controlled release and taste masking oral pharmaceutical composition
CA1265449A (fr) Dispositifs a debitage temporise de substances actives, et preparation desdits dispositifs
KR100712356B1 (ko) 서방성 제제 및 그의 제조방법
US4705695A (en) Method for coating pharmaceutical formulations
RU2127587C1 (ru) Устойчивые лекарственные формы с регулируемым выделением, имеющие акриловые полимерные покрытия, (варианты) и способ их получения
US4792452A (en) Controlled release formulation
FI121620B (fi) Menetelmiä aktiivisen aineen kontrolloidusti vapautuvan formulaation saamiseksi
US5149542A (en) Coating membrane and compositions prepared therefrom
FI91482B (fi) Menetelmä hitaasti vapauttavan kiinteän annostusmuodon valmistamiseksi
US4433076A (en) Coating agent for medicaments and methods for making and using the same
US5186943A (en) Compressed-molded preparations
EP0548448A1 (fr) Substrat stabilisé à libération contrôlée ayant une couche dérivée d'un dispersion aqueuse de polymère hydrophobe
IE83354B1 (en) Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
KR900005795B1 (ko) 피복 고형 제제의 제조방법
GB1593062A (en) Coatings
EP0365947A1 (fr) Forme de dosage
US3275518A (en) Tablet coating
EP0441245A1 (fr) Procédé de préparation de comprimés médicamenteux à libération retardée
US20220249385A1 (en) Extended release composition of tofacitinib
KR102543236B1 (ko) 벤토나이트를 포함하는 필름 코팅용 조성물
WO2005117839A1 (fr) Preparation de comprimes de paroxetine hydrochloride (hci) au moyen d'un procede de granulation par fusion
AU636538B2 (en) Buffered matrix aspirin tablet
JP2017507164A (ja) 放出制御組成物及び方法
HK1005686B (en) Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer

Legal Events

Date Code Title Description
MKLA Lapsed