CA2000263A1 - Facteurs stimulant les colonies cellulaires primitives et cellules lymphohematopoietiques parentes - Google Patents

Facteurs stimulant les colonies cellulaires primitives et cellules lymphohematopoietiques parentes

Info

Publication number
CA2000263A1
CA2000263A1 CA002000263A CA2000263A CA2000263A1 CA 2000263 A1 CA2000263 A1 CA 2000263A1 CA 002000263 A CA002000263 A CA 002000263A CA 2000263 A CA2000263 A CA 2000263A CA 2000263 A1 CA2000263 A1 CA 2000263A1
Authority
CA
Canada
Prior art keywords
cells
csf
cell
bone marrow
individual
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002000263A
Other languages
English (en)
Inventor
Michael J.P. Lawman
Helle B. Ohmann
Samuel K. Attah-Poku
Janette Heise-Qualtiere
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Saskatchewan
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2000263A1 publication Critical patent/CA2000263A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/11Coculture with; Conditioned medium produced by blood or immune system cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1394Bone marrow stromal cells; whole marrow

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA002000263A 1988-10-07 1989-10-06 Facteurs stimulant les colonies cellulaires primitives et cellules lymphohematopoietiques parentes Abandoned CA2000263A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US255,088 1981-04-17
US25508888A 1988-10-07 1988-10-07

Publications (1)

Publication Number Publication Date
CA2000263A1 true CA2000263A1 (fr) 1990-04-07

Family

ID=22966783

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002000263A Abandoned CA2000263A1 (fr) 1988-10-07 1989-10-06 Facteurs stimulant les colonies cellulaires primitives et cellules lymphohematopoietiques parentes

Country Status (6)

Country Link
EP (1) EP0437505A4 (fr)
JP (1) JPH04502853A (fr)
AU (1) AU4419289A (fr)
CA (1) CA2000263A1 (fr)
IL (1) IL91923A0 (fr)
WO (1) WO1990004018A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256560A (en) * 1988-10-07 1993-10-26 University Of Saskatchewan Primitive cell colony stimulating factors and lymphohematopoietic progenitor cells
RU2164240C2 (ru) * 1990-12-17 2001-03-20 Риджентс оф дзе Юниверсити оф Мичиган Способ культивирования, фибробласт, способ отделения клеток
WO1992014752A1 (fr) * 1991-02-22 1992-09-03 University Of Saskatchewan Vecteurs de facteurs de stimulation de populations de cellules primitives, anticorps et procedes d'application

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4714680B1 (en) * 1984-02-06 1995-06-27 Univ Johns Hopkins Human stem cells
JPH0753667B2 (ja) * 1985-08-09 1995-06-07 新技術開発事業団 骨髄移植療法補助剤
US4721096A (en) * 1986-04-18 1988-01-26 Marrow-Tech Incorporated Process for replicating bone marrow in vitro and using the same
US4808611A (en) * 1986-07-30 1989-02-28 Immunex Corporation Use of interleukin-1 to induce development of multipotent hemopoietic cell populations

Also Published As

Publication number Publication date
EP0437505A4 (en) 1991-11-13
JPH04502853A (ja) 1992-05-28
EP0437505A1 (fr) 1991-07-24
WO1990004018A1 (fr) 1990-04-19
IL91923A0 (en) 1990-06-10
AU4419289A (en) 1990-05-01

Similar Documents

Publication Publication Date Title
Wineman et al. Maintenance of high levels of pluripotent hematopoietic stem cells in vitro: effect of stromal cells and c-kit
Grabstein et al. Purification to homogeneity of B cell stimulating factor. A molecule that stimulates proliferation of multiple lymphokine-dependent cell lines.
JP2840443B2 (ja) 血小板産生刺激薬剤のためのil―7の使用
Song et al. Hematopoietic factor production by a cell line (TC-1) derived from adherent murine marrow cells
US20030087432A1 (en) Methods for regulating the specific lineages of cells produced in a human hematopoietic cell culture, methods for assaying the effect of substances on lineage-specific cell production, and cell compositions produced by these cultures
EP0243153A2 (fr) Expression de la protéine du G-CSF humain
RU2180850C2 (ru) Фармацевтическая композиция, содержащая c-kit-лиганд и гемопоэтический фактор, способ повышения уровней стволовых клеток в периферической крови, антагонист c-kit-лиганда, антисмысловая молекула нуклеиновой кислоты, способ увеличения уровней клеток периферической крови ex-vivo
JPH08505373A (ja) B細胞前駆体刺激因子
WO1992011355A1 (fr) Procede de culture et de transformation de compositions contenant des cellules souches humaines
JP2002155100A (ja) 幹細胞増殖因子
JPH11514879A (ja) 原始ヒト幹細胞を有するMp1リガンドの使用法
JPH10510147A (ja) 二次性免疫不全症の治療用薬剤の製造方法
US5256560A (en) Primitive cell colony stimulating factors and lymphohematopoietic progenitor cells
EP0049611A2 (fr) Facteur de croissance pour cellules T et son procédé de préparation
US4814434A (en) Inducer of T-suppressor cells
Ford et al. Production of B cell growth factor (s) by neoplastic B cells from hairy cell leukemia patients
Walker Separate precursor cells for macrophages and microglia in mouse brain: immunophenotypic and immunoregulatory properties of the progeny
Yoshida et al. Neutrophil chemotactic factors produced by a cell line from thyroid carcinoma
KR20000075749A (ko) 신규의 폴리펩티드, 그 폴리펩티드를 암호하는 dna 및 그용도
Hoffmann et al. Endotoxin-induced serum factor controlling differentiation of bone-marrow-derived lymphocytes.
JPH06510672A (ja) サプレッサーおよび前駆細胞
CA2000263A1 (fr) Facteurs stimulant les colonies cellulaires primitives et cellules lymphohematopoietiques parentes
EP0299206B1 (fr) ADF recombinante humaine
JPH09512165A (ja) インターロイキン15
AU1055988A (en) Human interleukin-4 muteins

Legal Events

Date Code Title Description
FZDE Discontinued