CA2046293A1 - Preparation d'ethenes a substitution - Google Patents

Preparation d'ethenes a substitution

Info

Publication number: CA2046293A1
Authority: CA; Canada
Prior art keywords: arylalkyl; alkylamines; nitrodithio; alkyl; heterocyclic
Prior art date: 1989-04-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA2046293A

Other languages

English (en)

Other versions

CA2046293C (fr

Inventor

Arthur Jackson

Graham Heyes

James Ian Grayson

Paul Edward Rowney

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Evonik LIL Ltd

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-04-05

Filing date

1990-04-04

Publication date

1990-10-06

1990-04-04 Application filed by Individual filed Critical Individual

1990-10-06 Publication of CA2046293A1 publication Critical patent/CA2046293A1/fr

1999-01-05 Application granted granted Critical

1999-01-05 Publication of CA2046293C publication Critical patent/CA2046293C/fr

2010-04-04 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

125000003710 aryl alkyl group Chemical group 0.000 abstract 3
ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 abstract 2
150000003973 alkyl amines Chemical class 0.000 abstract 2
WGQKYBSKWIADBV-UHFFFAOYSA-N benzylamine Chemical compound NCC1=CC=CC=C1 WGQKYBSKWIADBV-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
ZILSBZLQGRBMOR-UHFFFAOYSA-N 1,3-benzodioxol-5-ylmethanamine Chemical compound NCC1=CC=C2OCOC2=C1 ZILSBZLQGRBMOR-UHFFFAOYSA-N 0.000 abstract 1
ULOTWPOKIYOEQN-UHFFFAOYSA-N 2-nitroethanedithioic acid Chemical compound [O-][N+](=O)CC(S)=S ULOTWPOKIYOEQN-UHFFFAOYSA-N 0.000 abstract 1
DXSUORGKJZADET-UHFFFAOYSA-N 3,3-dimethylbutan-2-amine Chemical compound CC(N)C(C)(C)C DXSUORGKJZADET-UHFFFAOYSA-N 0.000 abstract 1
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical class [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000003282 alkyl amino group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
150000001412 amines Chemical class 0.000 abstract 1
150000003975 aryl alkyl amines Chemical group 0.000 abstract 1
KCIDZIIHRGYJAE-YGFYJFDDSA-L dipotassium;[(2r,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] phosphate Chemical class [K+].[K+].OC[C@H]1O[C@H](OP([O-])([O-])=O)[C@H](O)[C@@H](O)[C@H]1O KCIDZIIHRGYJAE-YGFYJFDDSA-L 0.000 abstract 1
125000005343 heterocyclic alkyl group Chemical group 0.000 abstract 1
-1 heterocyclic alkylamines Chemical group 0.000 abstract 1
XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/27—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and unsaturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Furan Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Luminescent Compositions (AREA)
Catalysts (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Underground Structures, Protecting, Testing And Restoring Foundations (AREA)
Ultra Sonic Daignosis Equipment (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

CA002046293A 1989-04-05 1990-04-04 Preparation d'ethenes a substitution Expired - Fee Related CA2046293C (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB898907700A GB8907700D0 (en)	1989-04-05	1989-04-05	Preparation of substituted ethenes
GB8907700.2		1989-04-05

Publications (2)

Publication Number	Publication Date
CA2046293A1 true CA2046293A1 (fr)	1990-10-06
CA2046293C CA2046293C (fr)	1999-01-05

Family

ID=10654520

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
CA002013841A Expired - Lifetime CA2013841C (fr)	1989-04-05	1990-04-04	Preparation d'ethenes substitues
CA002046293A Expired - Fee Related CA2046293C (fr)	1989-04-05	1990-04-04	Preparation d'ethenes a substitution

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
CA002013841A Expired - Lifetime CA2013841C (fr)	1989-04-05	1990-04-04	Preparation d'ethenes substitues

Country Status (25)

Country	Link
US (2)	US5371247A (fr)
EP (1)	EP0466733B1 (fr)
JP (2)	JP2954270B2 (fr)
KR (2)	KR920701140A (fr)
AT (2)	AT400030B (fr)
BE (1)	BE1003124A5 (fr)
CA (2)	CA2013841C (fr)
CH (1)	CH681008A5 (fr)
DE (2)	DE4010888C2 (fr)
DK (2)	DK84390A (fr)
ES (2)	ES2057549T3 (fr)
FI (2)	FI914672A0 (fr)
FR (1)	FR2645535B1 (fr)
GB (2)	GB8907700D0 (fr)
GR (1)	GR1001302B (fr)
HU (3)	HU9203905D0 (fr)
IE (2)	IE61894B1 (fr)
IL (1)	IL94002A (fr)
IN (3)	IN170319B (fr)
IT (1)	IT1242481B (fr)
NL (1)	NL194699C (fr)
PT (1)	PT93659B (fr)
SE (1)	SE509459C2 (fr)
WO (1)	WO1990012002A1 (fr)
ZA (1)	ZA902592B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU9203905D0 (en) *	1989-04-05	1993-04-28	Glaxo Group Ltd	Method for producing ranitidine
NZ245015A (en) *	1991-11-05	1995-12-21	Transkaryotic Therapies Inc	Delivery of human growth hormone through the administration of transfected cell lines encoding human growth hormone, which are physically protected from host immune response; the transfected cells and their production
US5393913A (en) *	1993-03-03	1995-02-28	Rhone-Poulenc Inc.	N-formylanilines
US5686588A (en) *	1995-08-16	1997-11-11	Yoo; Seo Hong	Amine acid salt compounds and process for the production thereof
GB9604048D0 (en) *	1996-02-26	1996-04-24	Grossman Stanley I	Labelling device and label
AU2001264174A1 (en)	2000-04-21	2001-11-07	Ioannis Pallikaris	Device for the shaping of a substance on the surface of a cornea
CN104119257B (zh) *	2013-04-26	2016-08-03	石家庄康坦福化工科技有限公司	一种1-甲胺基-1-甲硫基-2-硝基乙烯的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1554153A (en) *	1975-05-15	1979-10-17	Smith Kline French Lab	Process for making 2-amino-2-alkylthionitroethylenes
IT1168163B (it) *	1981-08-18	1987-05-20	Ausonia Farma Srl	Composto ad attivita' antiulcera, procedimento per la sua preparazione e composizioni farmaceutiche relative
PT76557B (en) *	1982-04-16	1986-01-21	Inke Sa	Process for preparing furan derivatives and addition salts thereof and of pharmaceutical compositions containing the same
ES8500618A1 (es) *	1983-06-21	1984-11-16	Union Quimico Farma	Procedimiento para la obtencion de n-metil-1-metiltio-2-nitroetenamina
GB8415254D0 (en) *	1984-06-15	1984-07-18	Glaxo Group Ltd	Amine derivatives
ES2003781A6 (es) *	1987-02-06	1988-11-16	Unio Quimico Farmaceutica S A	Procedimiento para la obtencion de n-metil-1-metiltio-2-nitroetenamina
HU9203905D0 (en) *	1989-04-05	1993-04-28	Glaxo Group Ltd	Method for producing ranitidine

1989
- 1989-04-05 HU HU9203905A patent/HU9203905D0/hu unknown
- 1989-04-05 GB GB898907700A patent/GB8907700D0/en active Pending
1990
- 1990-04-04 FI FI914672A patent/FI914672A0/fi not_active Application Discontinuation
- 1990-04-04 FI FI901696A patent/FI110939B/fi active IP Right Grant
- 1990-04-04 AT AT0080090A patent/AT400030B/de not_active IP Right Cessation
- 1990-04-04 IN IN247/MAS/90A patent/IN170319B/en unknown
- 1990-04-04 IT IT04782990A patent/IT1242481B/it active IP Right Grant
- 1990-04-04 KR KR1019910700948A patent/KR920701140A/ko not_active Withdrawn
- 1990-04-04 NL NL9000790A patent/NL194699C/nl not_active IP Right Cessation
- 1990-04-04 FR FR909004313A patent/FR2645535B1/fr not_active Expired - Lifetime
- 1990-04-04 GR GR900100250A patent/GR1001302B/el not_active IP Right Cessation
- 1990-04-04 ZA ZA902592A patent/ZA902592B/xx unknown
- 1990-04-04 DK DK084390A patent/DK84390A/da not_active Application Discontinuation
- 1990-04-04 US US07/730,963 patent/US5371247A/en not_active Expired - Fee Related
- 1990-04-04 DE DE4010888A patent/DE4010888C2/de not_active Expired - Lifetime
- 1990-04-04 CA CA002013841A patent/CA2013841C/fr not_active Expired - Lifetime
- 1990-04-04 DE DE69011677T patent/DE69011677T2/de not_active Expired - Fee Related
- 1990-04-04 DK DK90905245.8T patent/DK0466733T3/da active
- 1990-04-04 KR KR1019900004645A patent/KR0147820B1/ko not_active Expired - Lifetime
- 1990-04-04 JP JP2090034A patent/JP2954270B2/ja not_active Expired - Lifetime
- 1990-04-04 CA CA002046293A patent/CA2046293C/fr not_active Expired - Fee Related
- 1990-04-04 PT PT93659A patent/PT93659B/pt not_active IP Right Cessation
- 1990-04-04 HU HU902945A patent/HUT58285A/hu unknown
- 1990-04-04 EP EP90905245A patent/EP0466733B1/fr not_active Expired - Lifetime
- 1990-04-04 BE BE9000381A patent/BE1003124A5/fr not_active IP Right Cessation
- 1990-04-04 CH CH1132/90A patent/CH681008A5/fr not_active IP Right Cessation
- 1990-04-04 IE IE122290A patent/IE61894B1/en not_active IP Right Cessation
- 1990-04-04 US US07/503,987 patent/US5112995A/en not_active Expired - Lifetime
- 1990-04-04 IE IE122190A patent/IE65395B1/en not_active IP Right Cessation
- 1990-04-04 WO PCT/GB1990/000501 patent/WO1990012002A1/fr not_active Ceased
- 1990-04-04 ES ES90905245T patent/ES2057549T3/es not_active Expired - Lifetime
- 1990-04-04 HU HU902080A patent/HU207991B/hu unknown
- 1990-04-04 GB GB9007568A patent/GB2230526B/en not_active Expired - Lifetime
- 1990-04-04 AT AT90905245T patent/ATE110055T1/de not_active IP Right Cessation
- 1990-04-04 JP JP2505189A patent/JP3003946B2/ja not_active Expired - Fee Related
- 1990-04-04 IL IL9400290A patent/IL94002A/en not_active IP Right Cessation
- 1990-04-04 ES ES9000971A patent/ES2019246A6/es not_active Expired - Fee Related
- 1990-04-04 SE SE9001236A patent/SE509459C2/sv not_active IP Right Cessation
1991
- 1991-11-25 IN IN871MA1991 patent/IN173647B/en unknown
- 1991-11-25 IN IN872MA1991 patent/IN173648B/en unknown

Also Published As

Publication number	Publication date
IT9047829A0 (it)	1990-04-04
IN173648B (fr)	1994-06-18
FI901696A0 (fi)	1990-04-04
FR2645535A1 (fr)	1990-10-12
GR900100250A (en)	1991-09-27
JP3003946B2 (ja)	2000-01-31
DE4010888A1 (de)	1990-10-11
IE65395B1 (en)	1995-10-18
JPH04504254A (ja)	1992-07-30
GR1001302B (el)	1993-07-30
GB2230526A (en)	1990-10-24
DK84390A (da)	1990-10-06
DK0466733T3 (da)	1994-09-19
JPH0368569A (ja)	1991-03-25
NL194699B (nl)	2002-08-01
IN170319B (fr)	1992-03-14
ATE110055T1 (de)	1994-09-15
IT9047829A1 (it)	1991-10-04
EP0466733B1 (fr)	1994-08-17
KR0147820B1 (ko)	1998-08-17
NL9000790A (nl)	1990-11-01
CA2013841C (fr)	1999-10-12
DE69011677T2 (de)	1995-02-09
ZA902592B (en)	1991-04-24
NL194699C (nl)	2002-12-03
HUT58285A (en)	1992-02-28
KR900016119A (ko)	1990-11-12
CA2013841A1 (fr)	1990-10-05
BE1003124A5 (fr)	1991-12-03
HU902080D0 (en)	1990-07-28
DK84390D0 (da)	1990-04-04
DE4010888C2 (de)	2001-01-18
SE9001236L (sv)	1990-10-06
PT93659B (pt)	1996-08-30
HUT54977A (en)	1991-04-29
AT400030B (de)	1995-09-25
JP2954270B2 (ja)	1999-09-27
US5371247A (en)	1994-12-06
EP0466733A1 (fr)	1992-01-22
FR2645535B1 (fr)	1992-06-19
IE61894B1 (en)	1994-11-30
SE9001236D0 (sv)	1990-04-04
DE69011677D1 (de)	1994-09-22
IL94002A (en)	1994-11-11
GB8907700D0 (en)	1989-05-17
IT1242481B (it)	1994-03-17
CA2046293C (fr)	1999-01-05
ES2057549T3 (es)	1994-10-16
FI110939B (fi)	2003-04-30
GB2230526B (en)	1992-05-27
WO1990012002A1 (fr)	1990-10-18
HU207991B (en)	1993-07-28
IE901222L (en)	1990-10-05
IE901221L (en)	1990-10-05
ATA80090A (fr)	1995-01-15
ES2019246A6 (es)	1991-06-01
IL94002A0 (en)	1991-01-31
IN173647B (fr)	1994-06-18
KR920701140A (ko)	1992-08-11
PT93659A (pt)	1990-11-20
CH681008A5 (fr)	1992-12-31
FI914672A7 (fi)	1991-10-04
HU902945D0 (en)	1991-12-30
SE509459C2 (sv)	1999-02-01
HU9203905D0 (en)	1993-04-28
GB9007568D0 (en)	1990-05-30
US5112995A (en)	1992-05-12
FI914672A0 (fi)	1991-10-04

Legal Events

Date	Code	Title	Description
1991-11-20	EEER	Examination request
2005-04-04	MKLA	Lapsed

Publication	Publication Date	Title
KR880012526A (ko)	1988-11-28	l-페닐-3-나프탈레닐옥시프로판아민
IL123212A0 (en)	1998-09-24	Preparation of acid salts of amine compounds
ES2052714T3 (es)	1994-07-16	Un proceso para la preparacion de un compuesto denominado "cornexistina".
CA2046293A1 (fr)	1990-10-06	Preparation d'ethenes a substitution
CA2080221A1 (fr)	1991-10-18	Procede d'obtention de derives d'indolone a substituant
NZ508179A (en)	2002-10-25	Process for preparing crystalline salts of amoxycillin
ES2056072T3 (es)	1994-10-01	Procedimientos de preparacion del acido (+/-)-1,2-dihidro-3h-pirrolo (1,2-a) pirrol-1-carboxilico y compuestos relacionados.
IE820275L (en)	1982-08-09	Preparing pirbuterol
ES471356A1 (es)	1979-09-16	Procedimiento de obtencion de r,s-2,3,5,6-tetrahidro-6-fenil-imidazo (2,1-b)-tiazole (tetramisole)
GR81771B (fr)	1984-12-12
JPS5770847A (en)	1982-05-01	Preparation of 3-aminoglutaric acid dialkyl ester
PT81014A (en)	1985-09-01	Process for preparing the crystalline sodium salt of d-6-<alpha-<(2-oxo-3-furfurylideneamine-imidazolidin-1-yl)-carbonylamino>-2-thienyl-acetamido> -penicillanic acid useful as medicament
ES2014041A6 (es)	1990-06-16	Un procedimiento para preparar un derivado de amina.
JPS57120574A (en)	1982-07-27	Production of guanidine derivative
SG43092A1 (en)	1997-10-17	Process for preparing 5-arylhydantoin
JPS5463077A (en)	1979-05-21	Preparation of imidazoline derivative
JPS5663945A (en)	1981-05-30	Preparation of novel alkanolamine derivative
EP0098951A3 (fr)	1985-01-23	Dérivés d'aminobenzamide et leur préparation
JPS54125678A (en)	1979-09-29	Preparation of 4-hydroxy-6-methylnicotinic acid
JPS5557592A (en)	1980-04-28	Preparation of 3-carbamoyloxymethyl-2- or -3-cephem-4- carboxylic acid derivative
ES2003299A6 (es)	1988-10-16	Procedimiento de preparacion de derivados triazinas asimetricos condensados y de isomeros de los mismos