CA2071537C - Methode et reactif permettant de determiner certaines variations dans les nucleotides - Google Patents

Methode et reactif permettant de determiner certaines variations dans les nucleotides Download PDF

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Publication number
CA2071537C
CA2071537C CA002071537A CA2071537A CA2071537C CA 2071537 C CA2071537 C CA 2071537C CA 002071537 A CA002071537 A CA 002071537A CA 2071537 A CA2071537 A CA 2071537A CA 2071537 C CA2071537 C CA 2071537C
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Prior art keywords
primer
nucleotide
nucleic acid
detection step
acid polymer
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Expired - Fee Related
Application number
CA002071537A
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English (en)
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CA2071537A1 (fr
Inventor
Hans Soederlund
Ann-Christine Syvaenen
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SANGTEC MOLECULAR DIAGNOSTICS AB
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Sangtec Medical AB
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Publication of CA2071537C publication Critical patent/CA2071537C/fr
Anticipated expiration legal-status Critical
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6858Allele-specific amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
CA002071537A 1990-02-16 1991-02-15 Methode et reactif permettant de determiner certaines variations dans les nucleotides Expired - Fee Related CA2071537C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48200590A 1990-02-16 1990-02-16
US482,005 1990-02-16
PCT/FI1991/000046 WO1991013075A2 (fr) 1990-02-16 1991-02-15 Procede et reactif permettant de determiner des variations specifique de nucleotides

Publications (2)

Publication Number Publication Date
CA2071537A1 CA2071537A1 (fr) 1991-08-17
CA2071537C true CA2071537C (fr) 2003-02-11

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Application Number Title Priority Date Filing Date
CA002071537A Expired - Fee Related CA2071537C (fr) 1990-02-16 1991-02-15 Methode et reactif permettant de determiner certaines variations dans les nucleotides

Country Status (18)

Country Link
EP (1) EP0648280B1 (fr)
JP (1) JP2786011B2 (fr)
AT (1) ATE180019T1 (fr)
AU (1) AU642709B2 (fr)
CA (1) CA2071537C (fr)
DE (2) DE69131233T2 (fr)
DK (1) DK0648280T3 (fr)
ES (1) ES2072235T3 (fr)
FI (1) FI102297B (fr)
GR (2) GR950300047T1 (fr)
HU (1) HU211058B (fr)
IE (1) IE910525A1 (fr)
IL (1) IL97222A (fr)
NO (1) NO311529B1 (fr)
NZ (1) NZ237134A (fr)
PT (1) PT96776B (fr)
WO (1) WO1991013075A2 (fr)
ZA (1) ZA911152B (fr)

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Also Published As

Publication number Publication date
ES2072235T3 (es) 1999-07-16
NO923116L (no) 1992-08-10
AU642709B2 (en) 1993-10-28
NO311529B1 (no) 2001-12-03
WO1991013075A2 (fr) 1991-09-05
CA2071537A1 (fr) 1991-08-17
DK0648280T3 (da) 1999-11-01
ATE180019T1 (de) 1999-05-15
FI923653A0 (fi) 1992-08-14
PT96776A (pt) 1991-10-31
FI923653L (fi) 1992-08-14
EP0648280B1 (fr) 1999-05-12
HUT61330A (en) 1992-12-28
NO923116D0 (no) 1992-08-10
HU910516D0 (en) 1991-09-30
IL97222A0 (en) 1992-05-25
JP2786011B2 (ja) 1998-08-13
GR3030790T3 (en) 1999-11-30
HU211058B (en) 1995-10-30
EP0648280A1 (fr) 1995-04-19
AU7235191A (en) 1991-09-18
DE69131233D1 (de) 1999-06-17
WO1991013075A3 (fr) 1991-10-17
IE910525A1 (en) 1991-08-28
NZ237134A (en) 1992-06-25
PT96776B (pt) 1998-05-29
JPH05504477A (ja) 1993-07-15
ZA911152B (en) 1991-11-27
GR950300047T1 (en) 1995-07-31
FI102297B1 (fi) 1998-11-13
FI102297B (fi) 1998-11-13
IL97222A (en) 1995-08-31
DE648280T1 (de) 1995-11-30
DE69131233T2 (de) 1999-11-04
ES2072235T1 (es) 1995-07-16

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