CA2095152C - Methode d'aspiration d'un echantillon par pipette - Google Patents

Methode d'aspiration d'un echantillon par pipette Download PDF

Info

Publication number: CA2095152C
Authority: CA; Canada
Prior art keywords: sample; pipettor; pressure; aspiration; fluid
Prior art date: 1990-11-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

CA002095152A

Other languages

English (en)

Other versions

CA2095152A1 (fr

Inventor

Charles W. Brentz

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Abbott Laboratories

Original Assignee

Abbott Laboratories

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-11-09

Filing date

1991-11-08

Publication date

2003-02-18

1991-11-08 Application filed by Abbott Laboratories filed Critical Abbott Laboratories

1992-05-10 Publication of CA2095152A1 publication Critical patent/CA2095152A1/fr

2003-02-18 Application granted granted Critical

2003-02-18 Publication of CA2095152C publication Critical patent/CA2095152C/fr

2011-11-08 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

238000000034 method Methods 0.000 title claims abstract description 51
239000012530 fluid Substances 0.000 claims abstract description 57
230000008859 change Effects 0.000 claims abstract description 9
238000012544 monitoring process Methods 0.000 claims abstract description 9
239000003570 air Substances 0.000 claims description 39
239000012080 ambient air Substances 0.000 claims description 7
238000012360 testing method Methods 0.000 abstract description 16
239000000523 sample Substances 0.000 description 181
238000009530 blood pressure measurement Methods 0.000 description 17
239000006260 foam Substances 0.000 description 15
210000002966 serum Anatomy 0.000 description 14
244000309466 calf Species 0.000 description 12
238000006243 chemical reaction Methods 0.000 description 7
238000001514 detection method Methods 0.000 description 5
230000000694 effects Effects 0.000 description 5
238000012545 processing Methods 0.000 description 5
238000000429 assembly Methods 0.000 description 4
230000000712 assembly Effects 0.000 description 4
238000007664 blowing Methods 0.000 description 4
238000012864 cross contamination Methods 0.000 description 4
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230000008569 process Effects 0.000 description 4
239000000443 aerosol Substances 0.000 description 3
238000003556 assay Methods 0.000 description 3
239000003153 chemical reaction reagent Substances 0.000 description 3
230000009977 dual effect Effects 0.000 description 3
235000003642 hunger Nutrition 0.000 description 3
239000007788 liquid Substances 0.000 description 3
238000005259 measurement Methods 0.000 description 3
239000002245 particle Substances 0.000 description 3
210000002381 plasma Anatomy 0.000 description 3
230000002441 reversible effect Effects 0.000 description 3
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
239000004743 Polypropylene Substances 0.000 description 2
239000013060 biological fluid Substances 0.000 description 2
239000012472 biological sample Substances 0.000 description 2
235000013365 dairy product Nutrition 0.000 description 2
238000007654 immersion Methods 0.000 description 2
230000000737 periodic effect Effects 0.000 description 2
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238000010008 shearing Methods 0.000 description 2
210000002700 urine Anatomy 0.000 description 2
238000005406 washing Methods 0.000 description 2
206010003445 Ascites Diseases 0.000 description 1
241000283707 Capra Species 0.000 description 1
239000004698 Polyethylene Substances 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
210000004369 blood Anatomy 0.000 description 1
239000008280 blood Substances 0.000 description 1
239000007853 buffer solution Substances 0.000 description 1
210000004027 cell Anatomy 0.000 description 1
230000010261 cell growth Effects 0.000 description 1
210000001175 cerebrospinal fluid Anatomy 0.000 description 1
HGAZMNJKRQFZKS-UHFFFAOYSA-N chloroethene;ethenyl acetate Chemical compound ClC=C.CC(=O)OC=C HGAZMNJKRQFZKS-UHFFFAOYSA-N 0.000 description 1
238000004891 communication Methods 0.000 description 1
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230000008878 coupling Effects 0.000 description 1
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230000001419 dependent effect Effects 0.000 description 1
230000008030 elimination Effects 0.000 description 1
238000003379 elimination reaction Methods 0.000 description 1
238000002474 experimental method Methods 0.000 description 1
239000000284 extract Substances 0.000 description 1
239000001963 growth medium Substances 0.000 description 1
239000006194 liquid suspension Substances 0.000 description 1
230000007246 mechanism Effects 0.000 description 1
239000002184 metal Substances 0.000 description 1
239000011859 microparticle Substances 0.000 description 1
239000000203 mixture Substances 0.000 description 1
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Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
- G—PHYSICS
- G01—MEASURING; TESTING
- G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01F23/00—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm
- G01F23/14—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measurement of pressure
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/143—Quality control, feedback systems
- B01L2200/146—Employing pressure sensors
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/02—Identification, exchange or storage of information
- B01L2300/025—Displaying results or values with integrated means
- B01L2300/027—Digital display, e.g. LCD, LED
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
- G01N2035/1018—Detecting inhomogeneities, e.g. foam, bubbles, clots
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N2035/1025—Fluid level sensing

Landscapes

Physics & Mathematics (AREA)
General Physics & Mathematics (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Clinical Laboratory Science (AREA)
Immunology (AREA)
Pathology (AREA)
Fluid Mechanics (AREA)
Automatic Analysis And Handling Materials Therefor (AREA)
Sampling And Sample Adjustment (AREA)
Devices For Use In Laboratory Experiments (AREA)
Analysing Materials By The Use Of Radiation (AREA)

CA002095152A 1990-11-09 1991-11-08 Methode d'aspiration d'un echantillon par pipette Expired - Lifetime CA2095152C (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US61216090A	1990-11-09	1990-11-09
US612,160		1990-11-09
PCT/US1991/008375 WO1992008545A1 (fr)	1990-11-09	1991-11-08	Procede de prelevement d'echantillons par pipette

Publications (2)

Publication Number	Publication Date
CA2095152A1 CA2095152A1 (fr)	1992-05-10
CA2095152C true CA2095152C (fr)	2003-02-18

Family

ID=24451979

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002095152A Expired - Lifetime CA2095152C (fr)	1990-11-09	1991-11-08	Methode d'aspiration d'un echantillon par pipette

Country Status (6)

Country	Link
EP (1)	EP0556336A1 (fr)
JP (1)	JP3065100B2 (fr)
KR (1)	KR930702072A (fr)
AU (1)	AU652014B2 (fr)
CA (1)	CA2095152C (fr)
WO (1)	WO1992008545A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1995006878A1 (fr) *	1993-08-31	1995-03-09	Aloka Co., Ltd.	Appareil de pipettage dote d'une fonction de detection de fermeture
US5503036A (en) *	1994-05-09	1996-04-02	Ciba Corning Diagnostics Corp.	Obstruction detection circuit for sample probe
US5537880A (en) *	1995-06-07	1996-07-23	Abbott Laboratories	Automatic pipetting apparatus with leak detection and method of detecting a leak
US6158269A (en) *	1995-07-13	2000-12-12	Bayer Corporation	Method and apparatus for aspirating and dispensing sample fluids
US5750881A (en) *	1995-07-13	1998-05-12	Chiron Diagnostics Corporation	Method and apparatus for aspirating and dispensing sample fluids
US5965828A (en) *	1995-12-14	1999-10-12	Abbott Laboratories	Fluid handler and method of handling a fluid
US5915282A (en) *	1995-12-14	1999-06-22	Abbott Laboratories	Fluid handler and method of handling a fluid
US5723795A (en) *	1995-12-14	1998-03-03	Abbott Laboratories	Fluid handler and method of handling a fluid
JP3343038B2 (ja) *	1996-10-03	2002-11-11	ダイナボット株式会社	自動検体検査測定装置における分注方法
WO2001073396A1 (fr) *	2000-03-28	2001-10-04	Caliper Technologies, Corp.	Procedes permettant de reduire un report fluidique dans des dispositifs microfluidiques
JP4677076B2 (ja) *	2000-04-19	2011-04-27	アークレイ株式会社	液面検知装置
US7439076B1 (en) *	2000-06-30	2008-10-21	Hitachi, Ltd.	Liquid dispensing method and device
ES2250644T3 (es) *	2001-03-09	2006-04-16	Hamilton Bonaduz Ag	Procedimiento y dispositivo para evaluar un proceso de dosificacion de liquido.
EP1506413B1 (fr)	2002-05-17	2016-07-06	Becton Dickinson and Company	Systeme automatise destine a isoler, amplifier et detecter une sequence d'acides nucleiques cibles
WO2006123771A1 (fr)	2005-05-19	2006-11-23	Universal Bio Research Co., Ltd.	Procédé de détection de quantité injectée, et appareil d’injection et de surveillance d’aspiration de liquide
EP2031403B1 (fr)	2007-08-27	2016-02-17	Roche Diagnostics GmbH	Procédé de surveillance d'un procédé de transfert de fluides
US20100047898A1 (en) *	2008-08-19	2010-02-25	Biomerieux, Inc.	Mixing pipette
FR2977317B1 (fr) *	2011-06-28	2013-08-02	Gilson Sas	Procede de detection d'anomalies lors du remplissage d'un dispositif de dosage de liquide et dispositif de dosage de liquide
DE102011081186A1 (de) *	2011-08-18	2013-02-21	Hamilton Bonaduz Ag	Verfahren zum Detektieren der Oberfläche einer Flüssigkeitsprobe in einem Probenbehälter
JP5761753B2 (ja) *	2011-09-20	2015-08-12	株式会社日立ハイテクノロジーズ	自動分析装置及びその動作不良判定方法
JP7181821B2 (ja) *	2019-03-15	2022-12-01	株式会社日立ハイテク	自動分析装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4794085A (en) *	1984-07-19	1988-12-27	Eastman Kodak Company	Apparatus and method for detecting liquid penetration by a container used for aspirating and dispensing the liquid
JPS6375565A (ja) *	1986-09-18	1988-04-05	Toshiba Corp	サンプリングモニタ
JPS63109330A (ja) *	1986-10-27	1988-05-14	Kyoto Daiichi Kagaku:Kk	液面検出方法及びその装置
EP0341438A3 (fr) *	1988-05-13	1990-11-28	Abbott Laboratories	Capteur pneumatique
JPH087222B2 (ja) *	1990-01-18	1996-01-29	持田製薬株式会社	自動分注希釈装置

1991
- 1991-11-08 AU AU90758/91A patent/AU652014B2/en not_active Ceased
- 1991-11-08 EP EP92902011A patent/EP0556336A1/fr not_active Ceased
- 1991-11-08 CA CA002095152A patent/CA2095152C/fr not_active Expired - Lifetime
- 1991-11-08 WO PCT/US1991/008375 patent/WO1992008545A1/fr not_active Ceased
- 1991-11-08 KR KR1019930701367A patent/KR930702072A/ko not_active Withdrawn
- 1991-11-08 JP JP4501066A patent/JP3065100B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPH06501558A (ja)	1994-02-17
AU9075891A (en)	1992-06-11
AU652014B2 (en)	1994-08-11
EP0556336A1 (fr)	1993-08-25
JP3065100B2 (ja)	2000-07-12
CA2095152A1 (fr)	1992-05-10
WO1992008545A1 (fr)	1992-05-29
EP0556336A4 (fr)	1994-02-23
KR930702072A (ko)	1993-09-08

Legal Events

Date	Code	Title	Description
1998-08-11	EEER	Examination request
2011-11-08	MKEX	Expiry

Publication	Publication Date	Title
US5463895A (en)	1995-11-07	Sample pipetting method
CA2095152C (fr)	2003-02-18	Methode d'aspiration d'un echantillon par pipette
US7477997B2 (en)	2009-01-13	Method for ascertaining interferants in small liquid samples in an automated clinical analyzer
EP1295132B1 (fr)	2017-08-16	Technique de verification de l'integrite d'un transfert de liquide
US7926325B2 (en)	2011-04-19	Differentiating between abnormal sample viscosities and pipette clogging during aspiration
JP5123390B2 (ja)	2013-01-23	臨床サンプリング・ピペットにおける詰まりの検出
EP1059535B1 (fr)	2007-11-07	Procédé pour vérifier un volume aspiré de fluide dans un système diagnostique automatisé
US7634378B2 (en)	2009-12-15	Detection of insufficient sample during aspiration with a pipette
US7222526B2 (en)	2007-05-29	Liquid measurements using capacitive monitoring
US7804599B2 (en)	2010-09-28	Fluid volume verification system
US5965828A (en)	1999-10-12	Fluid handler and method of handling a fluid
CN102713607B (zh)	2014-08-20	用以在样本吸出和分配期间的探针缩回时确定凝块带出条件的方法、系统和设备
EP3058352B1 (fr)	2019-03-06	Procédés et appareil pour mesurer une pression d'aspiration
WO2004071931A2 (fr)	2004-08-26	Procede et appareil permettant d'aspirer le liquide contenu dans un recipient
EP2207039A2 (fr)	2010-07-14	Procédé et système de mesure de volumes de liquides pour contrôler les procédés de pipetage
JP7200357B2 (ja)	2023-01-06	実験器具の動作方法
US11815523B2 (en)	2023-11-14	Multi-point filtering liquid level detection methods and apparatus
WO2024252827A1 (fr)	2024-12-12	Dispositif d'analyse automatisé et procédé de détermination d'anomalie associé