CA2263940A1 - Vitamin d3 derivatives and remedies for inflammatory respiratory diseases prepared from the same - Google Patents

Vitamin d3 derivatives and remedies for inflammatory respiratory diseases prepared from the same Download PDF

Info

Publication number: CA2263940A1
Authority: CA; Canada
Prior art keywords: carbonyl; group; double bond; vitamin; derivative
Prior art date: 1997-06-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002263940A

Other languages

English (en)

French (fr)

Inventor

Hiroko Tanaka

Qingzhi Gao

Kenji Manabe

Minoru Furuya

Seiichi Ishizuka

Manabu Chokki

Hiroaki Mitsuhashi

Tadashi Kishimoto

Masayasu Tabe

Atsuo Hazato

Yasuji Sakuma

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Teijin Ltd

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-25

Filing date

1998-06-24

Publication date

1998-12-30

1998-06-24 Application filed by Individual filed Critical Individual

1998-12-30 Publication of CA2263940A1 publication Critical patent/CA2263940A1/en

Status Abandoned legal-status Critical Current

Links

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229940093609 tricaprylin Drugs 0.000 description 1
125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical compound CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 description 1
230000007306 turnover Effects 0.000 description 1
229940099259 vaseline Drugs 0.000 description 1
235000015112 vegetable and seed oil Nutrition 0.000 description 1
239000008158 vegetable oil Substances 0.000 description 1
230000003612 virological effect Effects 0.000 description 1
239000001993 wax Substances 0.000 description 1
229910052727 yttrium Inorganic materials 0.000 description 1
229910052725 zinc Inorganic materials 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Otolaryngology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

CA002263940A 1997-06-25 1998-06-24 Vitamin d3 derivatives and remedies for inflammatory respiratory diseases prepared from the same Abandoned CA2263940A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP16880397		1997-06-25
JP9/168803		1997-06-25
PCT/JP1998/002813 WO1998058909A1 (en)	1997-06-25	1998-06-24	Vitamin d3 derivatives and remedies for inflammatory respiratory diseases prepared from the same

Publications (1)

Publication Number	Publication Date
CA2263940A1 true CA2263940A1 (en)	1998-12-30

Family

ID=15874785

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002263940A Abandoned CA2263940A1 (en)	1997-06-25	1998-06-24	Vitamin d3 derivatives and remedies for inflammatory respiratory diseases prepared from the same

Country Status (12)

Country	Link
US (1)	US6028208A (de)
EP (1)	EP0970948B1 (de)
JP (1)	JP3992297B2 (de)
KR (1)	KR100593238B1 (de)
CN (1)	CN1090180C (de)
AT (1)	ATE290526T1 (de)
AU (1)	AU743399B2 (de)
CA (1)	CA2263940A1 (de)
DE (1)	DE69829279T2 (de)
ES (1)	ES2237841T3 (de)
TW (1)	TW473469B (de)
WO (1)	WO1998058909A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AUPP332898A0 (en)	1998-05-04	1998-05-28	Unisearch Limited	Pharmaceutical composition
AU758792B2 (en)	1998-10-23	2003-03-27	Teijin Limited	Vitamin D3 derivatives and remedies for inflammatory respiratory diseases containing the same
AU1798600A (en) *	1998-12-24	2000-07-31	Teijin Limited	Cystic fibrosis remedies containing vitamin D3 derivatives
US6627743B1 (en) *	1999-12-03	2003-09-30	Abbott Laboratories	6-O-methylerythromycin A crystal form III
AU7289801A (en)	2000-04-11	2001-10-23	Sandia Corp	Microelectromechanical apparatus for elevating and tilting a platform
US20030072717A1 (en) *	2001-02-23	2003-04-17	Vapotronics, Inc.	Inhalation device having an optimized air flow path
AU2002310054B2 (en) *	2001-05-21	2007-02-01	Injet Digital Aerosols Limited	Compositions for protein delivery via the pulmonary route
AU2002352726A1 (en)	2001-11-15	2003-06-10	Galileo Laboratories, Inc.	Formulations and methods for treatment or amelioration of inflammatory conditions
AU2003270783C1 (en) *	2002-09-20	2010-05-20	Merck Sharp & Dohme Corp.	Octahydro-2-H-naphtho[1,2-F] indole-4-carboxamide derivatives as selective glucocorticoid receptor modulators
AR041696A1 (es) *	2002-10-23	2005-05-26	Leo Pharm Prod Ltd	Compuestos analogos de vitamina d, composiciones que comprenden dichos compuestos analogos y su uso
PL376148A1 (en) *	2002-10-23	2005-12-27	Leo Pharma A/S	Vitamin d analogues, compositions comprising said analogues and their use
WO2006019169A1 (ja) *	2004-08-17	2006-02-23	Teijin Pharma Limited	３－エピビタミンｄ３誘導体およびそれを用いる治療剤
JP5161582B2 (ja) *	2004-11-22	2013-03-13	ウィスコンシン・アルムニ・リサーチ・ファウンデーション	１７，２０（ｚ）−デヒドロビタミンｄ類似体およびそれらの使用
ITMI20071616A1 (it)	2007-08-03	2009-02-04	Cosmo Spa	Processo enzimatico per l'ottenimento di 17-alfa monoesteri del cortexolone e/o suoi 9,11-deidroderivati.
US20090274696A1 (en) *	2008-04-29	2009-11-05	Wyeth	Methods for treating inflammation
CN103180293B (zh)	2010-10-25	2015-06-17	帝人制药株式会社	23-炔-维生素d3衍生物
US9700629B2 (en) *	2011-08-12	2017-07-11	Mitsubishi Gas Chemical Company, Inc.	Composition containing S-adenosyl-L-methionine with excellent storage stability
CN103232374B (zh) *	2013-05-08	2014-10-22	山东大学	一种侧链芳环修饰活性维生素d3类似物及其制备方法与应用
WO2016040570A2 (en)	2014-09-12	2016-03-17	Children's Medical Center Corporation	Dietary emulsion formulations and methods for using the same
EP3108879A1 (de)	2015-06-25	2016-12-28	Cassiopea S.p.A.	Hochkonzentrierte formulierung

Family Cites Families (8)

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Publication number	Priority date	Publication date	Assignee	Title
KR0144358B1 (ko) *	1988-04-21	1998-07-15	피. 라이달 크리스텐슨	비타민 d 동족체
US4851401A (en) *	1988-07-14	1989-07-25	Wisconsin Alumni Research Foundation	Novel cyclopentano-vitamin D analogs
ATE144250T1 (de) *	1991-12-26	1996-11-15	Wisconsin Alumni Res Found	26,27-dimethylen-1-alpha, 25-dihydroxyvitamin-d2 und 26,27-dihydroxyvitamin-d2 und verfahren zu ihrer herstellung
GB9203535D0 (en) *	1992-02-19	1992-04-08	Leo Pharm Prod Ltd	Novel treatment iii
DE4220757A1 (de) *	1992-06-24	1994-01-05	Schering Ag	Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
US5373004A (en) *	1993-11-24	1994-12-13	Wisconsin Alumni Research Foundation	26,28-methylene-1α, 25-dihydroxyvitamin D2 compounds
EP0712843B1 (de) *	1994-06-07	1999-11-17	Teijin Limited	Vitamin d3 derivat und verfahren zu dessen herstellung
JP3595025B2 (ja) *	1994-06-07	2004-12-02	帝人株式会社	ビタミンｄ３誘導体およびその製造法

1998
- 1998-06-24 CN CN98801176A patent/CN1090180C/zh not_active Expired - Fee Related
- 1998-06-24 US US09/242,665 patent/US6028208A/en not_active Expired - Fee Related
- 1998-06-24 CA CA002263940A patent/CA2263940A1/en not_active Abandoned
- 1998-06-24 AU AU79328/98A patent/AU743399B2/en not_active Ceased
- 1998-06-24 ES ES98929661T patent/ES2237841T3/es not_active Expired - Lifetime
- 1998-06-24 WO PCT/JP1998/002813 patent/WO1998058909A1/ja not_active Ceased
- 1998-06-24 TW TW087110184A patent/TW473469B/zh not_active IP Right Cessation
- 1998-06-24 KR KR1019997001474A patent/KR100593238B1/ko not_active Expired - Fee Related
- 1998-06-24 EP EP98929661A patent/EP0970948B1/de not_active Expired - Lifetime
- 1998-06-24 DE DE69829279T patent/DE69829279T2/de not_active Expired - Fee Related
- 1998-06-24 AT AT98929661T patent/ATE290526T1/de not_active IP Right Cessation
- 1998-06-24 JP JP50417599A patent/JP3992297B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ATE290526T1 (de)	2005-03-15
EP0970948A4 (de)	2002-02-06
JP3992297B2 (ja)	2007-10-17
DE69829279D1 (de)	2005-04-14
TW473469B (en)	2002-01-21
DE69829279T2 (de)	2006-03-30
AU7932898A (en)	1999-01-04
CN1236360A (zh)	1999-11-24
ES2237841T3 (es)	2005-08-01
CN1090180C (zh)	2002-09-04
EP0970948B1 (de)	2005-03-09
US6028208A (en)	2000-02-22
KR100593238B1 (ko)	2006-06-26
WO1998058909A1 (en)	1998-12-30
AU743399B2 (en)	2002-01-24
EP0970948A1 (de)	2000-01-12
KR20000068317A (ko)	2000-11-25

Legal Events

Date	Code	Title	Description
2002-03-07	EEER	Examination request
2009-03-27	FZDE	Discontinued

Publication	Publication Date	Title
CA2263940A1 (en)	1998-12-30	Vitamin d3 derivatives and remedies for inflammatory respiratory diseases prepared from the same
CA2125476C (en)	2003-02-11	20-methyl-substituted vitamin d derivatives
CA1340614C (en)	1999-06-29	Cyclopentano-vitamin d analogs
US5532391A (en)	1996-07-02	Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US6329538B1 (en)	2001-12-11	Vitamin D3 analogs
CA2044280C (en)	1999-12-21	Vitamin d analogues
JP3957303B2 (ja)	2007-08-15	１α−ヒドロキシ−２−メチレン−１９−ノル−ホモプレグナカルシフェロールの合成法
AU707942B2 (en)	1999-07-22	New vitamin D derivatives with substituents at C-25, process for their production, intermediate products and use for the production of pharmaceutical agents
AU6228199A (en)	2000-05-15	Vitamin D3 derivatives and remedies for inflammatory respiratory diseases containing the same
JP2007326871A (ja)	2007-12-20	ビタミンｄ化合物類
US4973721A (en)	1990-11-27	Production of novel vitamin D3 derivatives
JPWO1998058909A1 (ja)	1999-12-07	ビタミンｄ▲下３▼誘導体、およびそれを用いる炎症性呼吸器疾患治療剤
KR900008120B1 (ko)	1990-10-31	비타민 d₃유도체의 제조방법
US5250523A (en)	1993-10-05	Side chain unsaturated 1α-hydroxyvitanim D homologs
CZ170496A3 (en)	1997-02-12	Amine and amide derivatives of vitamin d
AU755701B2 (en)	2002-12-19	Method for making hydroxy-25-ene-vitamin D compounds
IL90065A (en)	1996-05-14	Hydroxysulfonic intermediates that find use in the synthesis of homologues of A1-Hydroxy Vitamin-D
US5354744A (en)	1994-10-11	Side chain unsaturated 1 alpha-hydroxyvitamin D analogs
IE70239B1 (en)	1996-11-13	Side-chain homologous vitamin D derivatives process for their production pharmaceutical preparations containing these derivatives and their use as pharmaceutical agents
EP1240137B1 (de)	2004-06-09	Verfahren zur herstellung von 24(s)-hydroxyvitamin d2
EP0250755A2 (de)	1988-01-07	Fluorine enthaltende Vitamin-D3-Derivate und Verfahren zu ihrer Herstellung
EP0468037B1 (de)	1995-03-22	Verfahren zur herstellung von vitamin-d2-verbindungen und ihrer 1-alpha hydrogenierten derivate
JPWO2000038692A1 (ja)	2002-04-09	ビタミンｄ３誘導体を用いる嚢胞性線維症治療剤
JPH04211052A (ja)	1992-08-03	ビタミンＤ２　化合物及び対応の１α−ヒドロキシル化誘導体の製造方法
JPH08239360A (ja)	1996-09-17	ビタミンｄ誘導体および製造方法