ATE290526T1 - Vitamin-d3?-derivate und aus diesen hergestellte heilmittel gegen entzündliche erkrankungen der atemwege - Google Patents

Vitamin-d3?-derivate und aus diesen hergestellte heilmittel gegen entzündliche erkrankungen der atemwege

Info

Publication number: ATE290526T1
Authority: AT; Austria
Prior art keywords: group; hydrogen atom; derivatives; vitamin; hydroxyl group
Prior art date: 1997-06-25

Application number

AT98929661T

Other languages

English (en)

Inventor

Hiroko Tanaka

Qingzhi Gao

Kenji Manabe

Minoru Furuya

Masayasu Tabe

Seiichi Ishizuka

Manabu Chokki

Hiroaki Mitsuhashi

Tadashi Kishimoto

Atsuo Hazato

Yasuji Sakuma

Original Assignee

Teijin Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-06-25

Filing date

1998-06-24

Publication date

2005-03-15

1998-06-24 Application filed by Teijin Ltd filed Critical Teijin Ltd

2005-03-15 Application granted granted Critical

2005-03-15 Publication of ATE290526T1 publication Critical patent/ATE290526T1/de

Links

208000027866 inflammatory disease Diseases 0.000 title 1
210000002345 respiratory system Anatomy 0.000 title 1
QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 7
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 5
125000000217 alkyl group Chemical group 0.000 abstract 4
125000004423 acyloxy group Chemical group 0.000 abstract 3
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000004414 alkyl thio group Chemical group 0.000 abstract 2
208000002874 Acne Vulgaris Diseases 0.000 abstract 1
201000004384 Alopecia Diseases 0.000 abstract 1
CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 1
201000004624 Dermatitis Diseases 0.000 abstract 1
206010020772 Hypertension Diseases 0.000 abstract 1
208000001132 Osteoporosis Diseases 0.000 abstract 1
201000004681 Psoriasis Diseases 0.000 abstract 1
125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
206010000496 acne Diseases 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
231100000360 alopecia Toxicity 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
206010012601 diabetes mellitus Diseases 0.000 abstract 1
230000002757 inflammatory effect Effects 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000004184 methoxymethyl group Chemical group [H]C([H])([H])OC([H])([H])* 0.000 abstract 1
208000023504 respiratory system disease Diseases 0.000 abstract 1
206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
125000001412 tetrahydropyranyl group Chemical group 0.000 abstract 1
125000004665 trialkylsilyl group Chemical group 0.000 abstract 1
150000003704 vitamin D3 derivatives Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Otolaryngology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT98929661T 1997-06-25 1998-06-24 Vitamin-d3?-derivate und aus diesen hergestellte heilmittel gegen entzündliche erkrankungen der atemwege ATE290526T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP16880397		1997-06-25
PCT/JP1998/002813 WO1998058909A1 (en)	1997-06-25	1998-06-24	Vitamin d3 derivatives and remedies for inflammatory respiratory diseases prepared from the same

Publications (1)

Publication Number	Publication Date
ATE290526T1 true ATE290526T1 (de)	2005-03-15

Family

ID=15874785

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98929661T ATE290526T1 (de)	1997-06-25	1998-06-24	Vitamin-d3?-derivate und aus diesen hergestellte heilmittel gegen entzündliche erkrankungen der atemwege

Country Status (12)

Country	Link
US (1)	US6028208A (de)
EP (1)	EP0970948B1 (de)
JP (1)	JP3992297B2 (de)
KR (1)	KR100593238B1 (de)
CN (1)	CN1090180C (de)
AT (1)	ATE290526T1 (de)
AU (1)	AU743399B2 (de)
CA (1)	CA2263940A1 (de)
DE (1)	DE69829279T2 (de)
ES (1)	ES2237841T3 (de)
TW (1)	TW473469B (de)
WO (1)	WO1998058909A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AUPP332898A0 (en) *	1998-05-04	1998-05-28	Unisearch Limited	Pharmaceutical composition
US6531460B1 (en)	1998-10-23	2003-03-11	Teijin Limited	Vitamin D, derivatives and remedies for inflammatory respiratory diseases containing the same
AU1798600A (en) *	1998-12-24	2000-07-31	Teijin Limited	Cystic fibrosis remedies containing vitamin D3 derivatives
US6627743B1 (en) *	1999-12-03	2003-09-30	Abbott Laboratories	6-O-methylerythromycin A crystal form III
WO2001077001A2 (en)	2000-04-11	2001-10-18	Sandia Corporation	Microelectromechanical apparatus for elevating and tilting a platform
US20030072717A1 (en) *	2001-02-23	2003-04-17	Vapotronics, Inc.	Inhalation device having an optimized air flow path
EP1389137B1 (de) *	2001-05-21	2006-07-19	InJet Digital Aerosols Limited	Zusammensetzungen für die freisetzung von protein auf dem pulmonalen weg
EP1450787A4 (de)	2001-11-15	2006-01-25	Galileo Pharmaceuticals Inc	Formulierungen und verfahren zur behandlung oder linderung von entzündlichen zuständen
EP1542996A4 (de) *	2002-09-20	2009-11-18	Merck & Co Inc	OCTAHYDRO-2H-NAPHTOç1,2-F INDOL-4-CARBONSûUREAMIDDERIVATE ALS SELEKTIVE MODULATOREN DES GLUCOCORTICOIDREZEPTORS
AR041696A1 (es) *	2002-10-23	2005-05-26	Leo Pharm Prod Ltd	Compuestos analogos de vitamina d, composiciones que comprenden dichos compuestos analogos y su uso
CA2500640A1 (en) *	2002-10-23	2004-05-06	Leo Pharma A/S	Vitamin d analogues, compositions comprising said analogues and their use
WO2006019169A1 (ja) *	2004-08-17	2006-02-23	Teijin Pharma Limited	３－エピビタミンｄ３誘導体およびそれを用いる治療剤
ATE469883T1 (de) *	2004-11-22	2010-06-15	Wisconsin Alumni Res Found	2-methylen-19-nor-1alpha-hydroxy-17- enhormopregnacalziferol und anwendungen davon
ITMI20071616A1 (it)	2007-08-03	2009-02-04	Cosmo Spa	Processo enzimatico per l'ottenimento di 17-alfa monoesteri del cortexolone e/o suoi 9,11-deidroderivati.
WO2009134917A2 (en) *	2008-04-29	2009-11-05	Wyeth	Methods for treating inflammation
US9006220B2 (en)	2010-10-25	2015-04-14	Teijin Pharma Limited	23-yne-vitamin D3 derivative
US9700629B2 (en) *	2011-08-12	2017-07-11	Mitsubishi Gas Chemical Company, Inc.	Composition containing S-adenosyl-L-methionine with excellent storage stability
CN103232374B (zh) *	2013-05-08	2014-10-22	山东大学	一种侧链芳环修饰活性维生素d3类似物及其制备方法与应用
US10328045B2 (en)	2014-09-12	2019-06-25	Children's Medical Center Corporation, Inc.	Dietary emulsion formulations and methods for using the same
EP3108879A1 (de)	2015-06-25	2016-12-28	Cassiopea S.p.A.	Hochkonzentrierte formulierung

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0412110B1 (de) *	1988-04-21	1993-07-07	Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab)	Vitamin d analoge
US4851401A (en) *	1988-07-14	1989-07-25	Wisconsin Alumni Research Foundation	Novel cyclopentano-vitamin D analogs
DE69214617T2 (de) *	1991-12-26	1997-05-28	Wisconsin Alumni Res Found	26,27-Dimethylen-1-Alpha, 25-Dihydroxyvitamin-D2 und 26,27-Dihydroxyvitamin-D2 und Verfahren zu ihrer Herstellung
GB9203535D0 (en) *	1992-02-19	1992-04-08	Leo Pharm Prod Ltd	Novel treatment iii
DE4220757A1 (de) *	1992-06-24	1994-01-05	Schering Ag	Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
US5373004A (en) *	1993-11-24	1994-12-13	Wisconsin Alumni Research Foundation	26,28-methylene-1α, 25-dihydroxyvitamin D2 compounds
JP3595025B2 (ja) *	1994-06-07	2004-12-02	帝人株式会社	ビタミンｄ３誘導体およびその製造法
DE69522589T2 (de) *	1994-06-07	2002-04-18	Teijin Ltd., Osaka	Vitamin D3-Derivate und ein Verfahren zu ihrer Herstellung

1998
- 1998-06-24 EP EP98929661A patent/EP0970948B1/de not_active Expired - Lifetime
- 1998-06-24 JP JP50417599A patent/JP3992297B2/ja not_active Expired - Fee Related
- 1998-06-24 CA CA002263940A patent/CA2263940A1/en not_active Abandoned
- 1998-06-24 ES ES98929661T patent/ES2237841T3/es not_active Expired - Lifetime
- 1998-06-24 WO PCT/JP1998/002813 patent/WO1998058909A1/ja not_active Ceased
- 1998-06-24 AT AT98929661T patent/ATE290526T1/de not_active IP Right Cessation
- 1998-06-24 KR KR1019997001474A patent/KR100593238B1/ko not_active Expired - Fee Related
- 1998-06-24 DE DE69829279T patent/DE69829279T2/de not_active Expired - Fee Related
- 1998-06-24 CN CN98801176A patent/CN1090180C/zh not_active Expired - Fee Related
- 1998-06-24 AU AU79328/98A patent/AU743399B2/en not_active Ceased
- 1998-06-24 TW TW087110184A patent/TW473469B/zh not_active IP Right Cessation
- 1998-06-24 US US09/242,665 patent/US6028208A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0970948A4 (de)	2002-02-06
EP0970948B1 (de)	2005-03-09
CN1090180C (zh)	2002-09-04
TW473469B (en)	2002-01-21
CN1236360A (zh)	1999-11-24
JP3992297B2 (ja)	2007-10-17
DE69829279T2 (de)	2006-03-30
US6028208A (en)	2000-02-22
KR100593238B1 (ko)	2006-06-26
CA2263940A1 (en)	1998-12-30
AU7932898A (en)	1999-01-04
AU743399B2 (en)	2002-01-24
EP0970948A1 (de)	2000-01-12
KR20000068317A (ko)	2000-11-25
WO1998058909A1 (en)	1998-12-30
ES2237841T3 (es)	2005-08-01
DE69829279D1 (de)	2005-04-14

Legal Events

Date

Code

Title

Description

2006-11-15

UEP

Publication of translation of european patent specification

Ref document number: 0970948

Country of ref document: EP

2009-03-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE290526T1 (de)	2005-03-15	Vitamin-d3?-derivate und aus diesen hergestellte heilmittel gegen entzündliche erkrankungen der atemwege
ATE126219T1 (de)	1995-08-15	Benzimidazolderivate, verfahren zu deren herstellung und anwendung.
UA74367C2 (uk)	2005-12-15	ПОХІДНІ 4,5-ДИГІДРО-1Н-ПІРАЗОЛУ, ЩО ВИЯВЛЯЮТЬ АНТАГОНІСТИЧНУ АКТИВНІСТЬ ЩОДО СВ<sub>1</sub>, СПОСІБ ЇХ ОДЕРЖАННЯ, ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ТА СПОСІБ ЇЇ ВИГОТОВЛЕННЯ, СПОСІБ ЛІКУВАННЯ ЗАХВОРЮВАНЬ (ВАРІАНТИ)
NO20092832L (no)	2003-02-17	Fremgangsmate for karbonylering av en forbindelse
NO932870D0 (no)	1993-08-12	Ny fremgangsmaate for fremstilling av 9-amino-6-demetyl-6-deoksyetracykliner
MXPA02009643A (es)	2003-03-10	Sintesis acortada de derivados de 3,3-diarilpropilamina.
ATE201397T1 (de)	2001-06-15	Vitamin d3 derivate und ein verfahren zu ihrer herstellung
ATE157966T1 (de)	1997-09-15	22-oxacholecalziferol-derivate und ihre herstellung
FI971227A0 (fi)	1997-03-24	Pyramidinyylipyratsolijohdannaisia
DK0768084T3 (da)	2002-10-14	Kræftmetastaseinhibitor
HUT57694A (en)	1991-12-30	Process for producing new beta-diketones and pharmaceutical compositions comprising same
ATE131061T1 (de)	1995-12-15	Förderung der osteogenese durch verwendung von vitamin d-derivaten.
DE60234024D1 (de)	2009-11-26	Neue retinoidderivate und eine pharmazeutische anti-krebs-zusammensetzung, die diese verbindungen enthält
ATE229937T1 (de)	2003-01-15	Vitamin d 3? derivate und verfahren zur herstellung derselben
ATE332907T1 (de)	2006-08-15	Racemoselektive herstellung rac- diorganosilylbis(2- methylbenzo eöindenyl)zirconium-verbindungen
ATE160566T1 (de)	1997-12-15	Amphotere tricyclische verbindungen als antihistaminische und antiallergische mittel
DE69708679D1 (de)	2002-01-10	Verfahren zur herstellung von steroidverbindungen
EP0250755A3 (en)	1988-03-30	Fluorine derivatives of vitamin d3 and process for producing the same
ATE23147T1 (de)	1986-11-15	Ungesaettigte verbindungen, ihre herstellung und anwendung.
DK0441515T3 (da)	1996-02-05	Tetralin- og chromanderivater i behandlingen af astma, artritis og beslægtede sygdomme
EP0623608A4 (de)	1995-04-19	Benzopyran-derivate, deren herstellung sowie diese als aktive bestandteile enthaltende arzneimittel.
MX9707911A (es)	1998-07-31	Derivados de amina 1-[w-(3,4-dihidro-2-naftalenil)alquil]- ciclica, proceso para su preparacion y composiciones farmaceuticas que contienen los mismos.