ATE290526T1 - Vitamin-d3?-derivate und aus diesen hergestellte heilmittel gegen entzündliche erkrankungen der atemwege - Google Patents
Vitamin-d3?-derivate und aus diesen hergestellte heilmittel gegen entzündliche erkrankungen der atemwegeInfo
- Publication number
- ATE290526T1 ATE290526T1 AT98929661T AT98929661T ATE290526T1 AT E290526 T1 ATE290526 T1 AT E290526T1 AT 98929661 T AT98929661 T AT 98929661T AT 98929661 T AT98929661 T AT 98929661T AT E290526 T1 ATE290526 T1 AT E290526T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- hydrogen atom
- derivatives
- vitamin
- hydroxyl group
- Prior art date
Links
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 210000002345 respiratory system Anatomy 0.000 title 1
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 7
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000004423 acyloxy group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- 201000004384 Alopecia Diseases 0.000 abstract 1
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 1
- 201000004624 Dermatitis Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 231100000360 alopecia Toxicity 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000004184 methoxymethyl group Chemical group [H]C([H])([H])OC([H])([H])* 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 abstract 1
- 125000004665 trialkylsilyl group Chemical group 0.000 abstract 1
- 150000003704 vitamin D3 derivatives Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16880397 | 1997-06-25 | ||
| PCT/JP1998/002813 WO1998058909A1 (en) | 1997-06-25 | 1998-06-24 | Vitamin d3 derivatives and remedies for inflammatory respiratory diseases prepared from the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE290526T1 true ATE290526T1 (de) | 2005-03-15 |
Family
ID=15874785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98929661T ATE290526T1 (de) | 1997-06-25 | 1998-06-24 | Vitamin-d3?-derivate und aus diesen hergestellte heilmittel gegen entzündliche erkrankungen der atemwege |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6028208A (de) |
| EP (1) | EP0970948B1 (de) |
| JP (1) | JP3992297B2 (de) |
| KR (1) | KR100593238B1 (de) |
| CN (1) | CN1090180C (de) |
| AT (1) | ATE290526T1 (de) |
| AU (1) | AU743399B2 (de) |
| CA (1) | CA2263940A1 (de) |
| DE (1) | DE69829279T2 (de) |
| ES (1) | ES2237841T3 (de) |
| TW (1) | TW473469B (de) |
| WO (1) | WO1998058909A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPP332898A0 (en) * | 1998-05-04 | 1998-05-28 | Unisearch Limited | Pharmaceutical composition |
| WO2000024712A1 (en) * | 1998-10-23 | 2000-05-04 | Teijin Limited | Vitamin d3 derivatives and remedies for inflammatory respiratory diseases containing the same |
| WO2000038692A1 (fr) * | 1998-12-24 | 2000-07-06 | Teijin Limited | Remedes contre la mucoviscidose contenant des derives de la vitamine d¿3? |
| US6627743B1 (en) * | 1999-12-03 | 2003-09-30 | Abbott Laboratories | 6-O-methylerythromycin A crystal form III |
| AU7289801A (en) | 2000-04-11 | 2001-10-23 | Sandia Corp | Microelectromechanical apparatus for elevating and tilting a platform |
| US20030072717A1 (en) * | 2001-02-23 | 2003-04-17 | Vapotronics, Inc. | Inhalation device having an optimized air flow path |
| CN1236831C (zh) * | 2001-05-21 | 2006-01-18 | 茵捷特数码浮质有限公司 | 用于经肺部途径递送蛋白质的组合物 |
| AU2002352726A1 (en) | 2001-11-15 | 2003-06-10 | Galileo Laboratories, Inc. | Formulations and methods for treatment or amelioration of inflammatory conditions |
| CA2499150A1 (en) * | 2002-09-20 | 2004-04-01 | Merck & Co., Inc. | Octahydro-2-h-naphtho[1,2-f] indole-4-carboxamide derivatives as selective glucocorticoid receptor modulators |
| AR041696A1 (es) | 2002-10-23 | 2005-05-26 | Leo Pharm Prod Ltd | Compuestos analogos de vitamina d, composiciones que comprenden dichos compuestos analogos y su uso |
| MXPA05003499A (es) * | 2002-10-23 | 2005-06-17 | Leo Pharma As | Analogos de vitamina d, composiciones que los comprenden y su uso. |
| WO2006019169A1 (ja) * | 2004-08-17 | 2006-02-23 | Teijin Pharma Limited | 3-エピビタミンd3誘導体およびそれを用いる治療剤 |
| ES2344989T3 (es) * | 2004-11-22 | 2010-09-13 | Wisconsin Alumni Research Foundation | Analogos de 17,20(e)-deshidro vitamina d y sus usos. |
| ITMI20071616A1 (it) | 2007-08-03 | 2009-02-04 | Cosmo Spa | Processo enzimatico per l'ottenimento di 17-alfa monoesteri del cortexolone e/o suoi 9,11-deidroderivati. |
| JP2011523401A (ja) * | 2008-04-29 | 2011-08-11 | ワイス・エルエルシー | 炎症を治療するための方法 |
| HUE025554T2 (en) | 2010-10-25 | 2016-02-29 | Teijin Pharma Ltd | Vitamin D3-23-in derivative |
| JP6044540B2 (ja) * | 2011-08-12 | 2016-12-14 | 三菱瓦斯化学株式会社 | 保存安定性に優れたs−アデノシル−l−メチオニン含有組成物 |
| CN103232374B (zh) * | 2013-05-08 | 2014-10-22 | 山东大学 | 一种侧链芳环修饰活性维生素d3类似物及其制备方法与应用 |
| US10328045B2 (en) | 2014-09-12 | 2019-06-25 | Children's Medical Center Corporation, Inc. | Dietary emulsion formulations and methods for using the same |
| EP3108879A1 (de) | 2015-06-25 | 2016-12-28 | Cassiopea S.p.A. | Hochkonzentrierte formulierung |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0412110B1 (de) * | 1988-04-21 | 1993-07-07 | Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) | Vitamin d analoge |
| US4851401A (en) * | 1988-07-14 | 1989-07-25 | Wisconsin Alumni Research Foundation | Novel cyclopentano-vitamin D analogs |
| AU656829B2 (en) * | 1991-12-26 | 1995-02-16 | Wisconsin Alumni Research Foundation | 26, 27-dimethylene-1 alpha, 25-dihydroxyvitamin D2 and 26,27-dihydroxyvitamin D2 and methods for preparing same |
| GB9203535D0 (en) * | 1992-02-19 | 1992-04-08 | Leo Pharm Prod Ltd | Novel treatment iii |
| DE4220757A1 (de) * | 1992-06-24 | 1994-01-05 | Schering Ag | Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln |
| US5373004A (en) * | 1993-11-24 | 1994-12-13 | Wisconsin Alumni Research Foundation | 26,28-methylene-1α, 25-dihydroxyvitamin D2 compounds |
| ATE201397T1 (de) * | 1994-06-07 | 2001-06-15 | Teijin Ltd | Vitamin d3 derivate und ein verfahren zu ihrer herstellung |
| JP3595025B2 (ja) * | 1994-06-07 | 2004-12-02 | 帝人株式会社 | ビタミンd3 誘導体およびその製造法 |
-
1998
- 1998-06-24 AT AT98929661T patent/ATE290526T1/de not_active IP Right Cessation
- 1998-06-24 ES ES98929661T patent/ES2237841T3/es not_active Expired - Lifetime
- 1998-06-24 EP EP98929661A patent/EP0970948B1/de not_active Expired - Lifetime
- 1998-06-24 TW TW087110184A patent/TW473469B/zh not_active IP Right Cessation
- 1998-06-24 US US09/242,665 patent/US6028208A/en not_active Expired - Fee Related
- 1998-06-24 DE DE69829279T patent/DE69829279T2/de not_active Expired - Fee Related
- 1998-06-24 AU AU79328/98A patent/AU743399B2/en not_active Ceased
- 1998-06-24 KR KR1019997001474A patent/KR100593238B1/ko not_active Expired - Fee Related
- 1998-06-24 CN CN98801176A patent/CN1090180C/zh not_active Expired - Fee Related
- 1998-06-24 JP JP50417599A patent/JP3992297B2/ja not_active Expired - Fee Related
- 1998-06-24 CA CA002263940A patent/CA2263940A1/en not_active Abandoned
- 1998-06-24 WO PCT/JP1998/002813 patent/WO1998058909A1/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CN1090180C (zh) | 2002-09-04 |
| KR100593238B1 (ko) | 2006-06-26 |
| EP0970948A4 (de) | 2002-02-06 |
| EP0970948B1 (de) | 2005-03-09 |
| AU743399B2 (en) | 2002-01-24 |
| DE69829279D1 (de) | 2005-04-14 |
| CN1236360A (zh) | 1999-11-24 |
| EP0970948A1 (de) | 2000-01-12 |
| KR20000068317A (ko) | 2000-11-25 |
| AU7932898A (en) | 1999-01-04 |
| US6028208A (en) | 2000-02-22 |
| CA2263940A1 (en) | 1998-12-30 |
| JP3992297B2 (ja) | 2007-10-17 |
| TW473469B (en) | 2002-01-21 |
| ES2237841T3 (es) | 2005-08-01 |
| DE69829279T2 (de) | 2006-03-30 |
| WO1998058909A1 (en) | 1998-12-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0970948 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |