CA2267497C - Compositions comestibles basses calories d'un excipient et d'un ingredient actif et leurs procedes de preparation - Google Patents
Compositions comestibles basses calories d'un excipient et d'un ingredient actif et leurs procedes de preparation Download PDFInfo
- Publication number
- CA2267497C CA2267497C CA002267497A CA2267497A CA2267497C CA 2267497 C CA2267497 C CA 2267497C CA 002267497 A CA002267497 A CA 002267497A CA 2267497 A CA2267497 A CA 2267497A CA 2267497 C CA2267497 C CA 2267497C
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- Canada
- Prior art keywords
- gel
- water
- glass
- acid
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 239000000203 mixture Substances 0.000 title claims abstract description 54
- 238000000034 method Methods 0.000 title claims abstract description 26
- 239000004480 active ingredient Substances 0.000 title claims description 30
- 238000002360 preparation method Methods 0.000 title description 20
- 239000011521 glass Substances 0.000 claims abstract description 67
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 44
- 150000001413 amino acids Chemical class 0.000 claims abstract description 30
- 239000000796 flavoring agent Substances 0.000 claims abstract description 21
- 150000001455 metallic ions Chemical class 0.000 claims abstract description 18
- 239000003765 sweetening agent Substances 0.000 claims abstract description 16
- 239000007795 chemical reaction product Substances 0.000 claims abstract description 10
- 235000013355 food flavoring agent Nutrition 0.000 claims abstract description 8
- 239000003814 drug Substances 0.000 claims abstract description 5
- 229940124597 therapeutic agent Drugs 0.000 claims abstract description 5
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- 235000021311 artificial sweeteners Nutrition 0.000 claims description 18
- 150000001732 carboxylic acid derivatives Chemical class 0.000 claims description 18
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- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Substances OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 15
- 235000021092 sugar substitutes Nutrition 0.000 claims description 14
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 claims description 10
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims description 10
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- 239000011777 magnesium Substances 0.000 claims description 9
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- 239000000047 product Substances 0.000 claims description 9
- 239000004471 Glycine Substances 0.000 claims description 8
- WBZFUFAFFUEMEI-UHFFFAOYSA-M Acesulfame k Chemical group [K+].CC1=CC(=O)[N-]S(=O)(=O)O1 WBZFUFAFFUEMEI-UHFFFAOYSA-M 0.000 claims description 7
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 7
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- JJMDCOVWQOJGCB-UHFFFAOYSA-N 5-aminopentanoic acid Chemical compound [NH3+]CCCCC([O-])=O JJMDCOVWQOJGCB-UHFFFAOYSA-N 0.000 claims description 4
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- 239000001384 succinic acid Substances 0.000 claims description 4
- SLXKOJJOQWFEFD-UHFFFAOYSA-N 6-aminohexanoic acid Chemical compound NCCCCCC(O)=O SLXKOJJOQWFEFD-UHFFFAOYSA-N 0.000 claims description 3
- 229960002684 aminocaproic acid Drugs 0.000 claims description 3
- 150000003628 tricarboxylic acids Chemical class 0.000 claims description 3
- HFVMEOPYDLEHBR-UHFFFAOYSA-N (2-fluorophenyl)-phenylmethanol Chemical compound C=1C=CC=C(F)C=1C(O)C1=CC=CC=C1 HFVMEOPYDLEHBR-UHFFFAOYSA-N 0.000 claims description 2
- GMKMEZVLHJARHF-UHFFFAOYSA-N (2R,6R)-form-2.6-Diaminoheptanedioic acid Natural products OC(=O)C(N)CCCC(N)C(O)=O GMKMEZVLHJARHF-UHFFFAOYSA-N 0.000 claims description 2
- PXRKCOCTEMYUEG-UHFFFAOYSA-N 5-aminoisoindole-1,3-dione Chemical compound NC1=CC=C2C(=O)NC(=O)C2=C1 PXRKCOCTEMYUEG-UHFFFAOYSA-N 0.000 claims description 2
- XDOLZJYETYVRKV-UHFFFAOYSA-N 7-Aminoheptanoic acid Chemical compound NCCCCCCC(O)=O XDOLZJYETYVRKV-UHFFFAOYSA-N 0.000 claims description 2
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- AHLPHDHHMVZTML-UHFFFAOYSA-N Orn-delta-NH2 Natural products NCCCC(N)C(O)=O AHLPHDHHMVZTML-UHFFFAOYSA-N 0.000 claims description 2
- UTJLXEIPEHZYQJ-UHFFFAOYSA-N Ornithine Natural products OC(=O)C(C)CCCN UTJLXEIPEHZYQJ-UHFFFAOYSA-N 0.000 claims description 2
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- GMKMEZVLHJARHF-SYDPRGILSA-N meso-2,6-diaminopimelic acid Chemical compound [O-]C(=O)[C@@H]([NH3+])CCC[C@@H]([NH3+])C([O-])=O GMKMEZVLHJARHF-SYDPRGILSA-N 0.000 claims description 2
- 229960003104 ornithine Drugs 0.000 claims description 2
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- 235000002906 tartaric acid Nutrition 0.000 claims description 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims description 2
- PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 claims 5
- IPCXNCATNBAPKW-UHFFFAOYSA-N zinc;hydrate Chemical compound O.[Zn] IPCXNCATNBAPKW-UHFFFAOYSA-N 0.000 claims 2
- UCMIRNVEIXFBKS-UHFFFAOYSA-N beta-alanine Chemical compound NCCC(O)=O UCMIRNVEIXFBKS-UHFFFAOYSA-N 0.000 claims 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical group C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 claims 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract description 2
- 239000002537 cosmetic Substances 0.000 abstract description 2
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- 239000000891 luminescent agent Substances 0.000 abstract description 2
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- 235000000346 sugar Nutrition 0.000 description 26
- CPLXHLVBOLITMK-UHFFFAOYSA-N magnesium oxide Inorganic materials [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 description 21
- ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical compound NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 description 16
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- HZRUTVAFDWTKGD-JEDNCBNOSA-N (2s)-2,6-diaminohexanoic acid;hydrate Chemical compound O.NCCCC[C@H](N)C(O)=O HZRUTVAFDWTKGD-JEDNCBNOSA-N 0.000 description 10
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- 239000005337 ground glass Substances 0.000 description 8
- 239000005720 sucrose Substances 0.000 description 8
- YASYEJJMZJALEJ-UHFFFAOYSA-N Citric acid monohydrate Chemical compound O.OC(=O)CC(O)(C(O)=O)CC(O)=O YASYEJJMZJALEJ-UHFFFAOYSA-N 0.000 description 6
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- 150000003445 sucroses Chemical class 0.000 description 1
- 235000019630 tart taste sensations Nutrition 0.000 description 1
- 229940116411 terpineol Drugs 0.000 description 1
- 230000036962 time dependent Effects 0.000 description 1
- 235000015149 toffees Nutrition 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 235000013337 tricalcium citrate Nutrition 0.000 description 1
- 229940057402 undecyl alcohol Drugs 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 235000020234 walnut Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/70—Fixation, conservation, or encapsulation of flavouring agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Food Science & Technology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Polymers & Plastics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Physiology (AREA)
- Mycology (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Seasonings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Des compositions comestibles basses calories contiennent, en plus d'un ingrédient actif, tel que des agents aromatisants, et des agents édulcorants, des agents thérapeutiques, des agents cosmétiques et des agents luminescents, un excipient se présentant sous forme de gel ou de verre, lequel est le produit de réaction amorphe d'un acide aminé de base, d'un acide carboxylique, d'une source d'ions métalliques et d'eau. L'invention concerne également des procédés de production desdites compositions.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1996/015972 WO1998014173A1 (fr) | 1996-10-04 | 1996-10-04 | Compositions comestibles basses calories d'un excipient et d'un ingredient actif et leurs procedes de preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2267497A1 CA2267497A1 (fr) | 1998-04-09 |
| CA2267497C true CA2267497C (fr) | 2004-05-25 |
Family
ID=22255911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002267497A Expired - Fee Related CA2267497C (fr) | 1996-10-04 | 1996-10-04 | Compositions comestibles basses calories d'un excipient et d'un ingredient actif et leurs procedes de preparation |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1006814A1 (fr) |
| JP (1) | JP2000509997A (fr) |
| CA (1) | CA2267497C (fr) |
| WO (1) | WO1998014173A1 (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU3483299A (en) * | 1998-04-10 | 1999-11-01 | Natura, Inc. | Use of exalt or sucrelesse in a lozenge, syrup or spray |
| US6294207B1 (en) * | 1999-11-01 | 2001-09-25 | Albion International, Inc. | Calcium fortification of oleaginous foods |
| BR0015182A (pt) * | 1999-11-01 | 2002-07-16 | Albion Int | Composições e métodos para fortificação de cálcio de produtos de leiteria e alimentos oleaginosos |
| US20030035875A1 (en) * | 2001-04-03 | 2003-02-20 | Dulebohn Joel I. | Composition for improving the taste and sweetness profile of beverages having intense sweeteners |
| HUP0202482A2 (hu) * | 2002-07-25 | 2004-09-28 | István Horváth | Eljárás flavintartalmú édesipari termékek készítésére és az eljárással létrehozott édesipari termékek |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4981698A (en) * | 1986-12-23 | 1991-01-01 | Warner-Lambert Co. | Multiple encapsulated sweetener delivery system and method of preparation |
| US5387431A (en) * | 1991-10-25 | 1995-02-07 | Fuisz Technologies Ltd. | Saccharide-based matrix |
-
1996
- 1996-10-04 CA CA002267497A patent/CA2267497C/fr not_active Expired - Fee Related
- 1996-10-04 WO PCT/US1996/015972 patent/WO1998014173A1/fr not_active Ceased
- 1996-10-04 EP EP96936201A patent/EP1006814A1/fr not_active Withdrawn
- 1996-10-04 JP JP10516469A patent/JP2000509997A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1006814A4 (fr) | 2000-06-14 |
| CA2267497A1 (fr) | 1998-04-09 |
| WO1998014173A1 (fr) | 1998-04-09 |
| EP1006814A1 (fr) | 2000-06-14 |
| JP2000509997A (ja) | 2000-08-08 |
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| Sträter | Marie-Christel Wijers |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |