CA2302647A1 - Expression of gonadotropins in dictyostelium - Google Patents

Expression of gonadotropins in dictyostelium Download PDF

Info

Publication number
CA2302647A1
CA2302647A1 CA002302647A CA2302647A CA2302647A1 CA 2302647 A1 CA2302647 A1 CA 2302647A1 CA 002302647 A CA002302647 A CA 002302647A CA 2302647 A CA2302647 A CA 2302647A CA 2302647 A1 CA2302647 A1 CA 2302647A1
Authority
CA
Canada
Prior art keywords
dictyostelium
hcg
gonadotropin
gonadotropins
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002302647A
Other languages
English (en)
French (fr)
Inventor
Peter Diederik Jan Grootenhuis
Judith Christina Heikoop
Maarten Herman Karel Linskens
Petrus Johannes Maria Van Haastert
Mieke Blaauw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo Nobel NV
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2302647A1 publication Critical patent/CA2302647A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA002302647A 1997-09-08 1998-09-02 Expression of gonadotropins in dictyostelium Abandoned CA2302647A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97202757 1997-09-08
EP97202757.7 1997-09-08
PCT/EP1998/005717 WO1999013081A1 (en) 1997-09-08 1998-09-02 EXPRESSION OF GONADOTROPINS IN $i(DICTYOSTELIUM)

Publications (1)

Publication Number Publication Date
CA2302647A1 true CA2302647A1 (en) 1999-03-18

Family

ID=8228713

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002302647A Abandoned CA2302647A1 (en) 1997-09-08 1998-09-02 Expression of gonadotropins in dictyostelium

Country Status (16)

Country Link
EP (1) EP1012290A1 (tr)
JP (1) JP2001515721A (tr)
KR (1) KR20010023749A (tr)
CN (1) CN1269834A (tr)
AR (1) AR013468A1 (tr)
AU (1) AU746780B2 (tr)
BR (1) BR9812043A (tr)
CA (1) CA2302647A1 (tr)
HU (1) HUP0004599A3 (tr)
IL (1) IL134589A0 (tr)
NO (1) NO20001178L (tr)
NZ (1) NZ502964A (tr)
PL (1) PL339259A1 (tr)
TR (1) TR200000618T2 (tr)
WO (1) WO1999013081A1 (tr)
ZA (1) ZA987497B (tr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014159813A1 (en) 2013-03-13 2014-10-02 Moderna Therapeutics, Inc. Long-lived polynucleotide molecules

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001058493A1 (en) * 2000-02-11 2001-08-16 Maxygen Aps Conjugates of follicle stimulating hormones
CA2412882A1 (en) * 2000-06-30 2002-01-10 Maxygen Aps Peptide extended glycosylated polypeptides
RS21004A (sr) * 2001-09-12 2006-12-15 Aplied Research Systems Ars Holding N.V. Upotreba hcg u kontrolisanoj hiperstimulaciji ovarijuma
MXPA04002257A (es) 2001-09-12 2004-07-23 Applied Research Systems Uso de gonadotropina corionica humana (gch) y su hormona de liberacion (hl) en hiperestimulacion ovarica controlada.
AU2002324183B2 (en) * 2001-09-12 2007-10-25 Merck Serono Sa Use of hCG and LH in controlled ovarian hyperstimulation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE342061T1 (de) * 1994-02-18 2006-11-15 Applied Research Systems Verwendung eines nicht-neutralisierenden antikörpers spezifisch für die beta-untereinheit von luteinisierendem hormon zur erhöhung der fertilität
US5691455A (en) * 1995-10-24 1997-11-25 Akzo Nobel N.V. Gonadotropins with non-native disulfide bridges

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014159813A1 (en) 2013-03-13 2014-10-02 Moderna Therapeutics, Inc. Long-lived polynucleotide molecules

Also Published As

Publication number Publication date
AR013468A1 (es) 2000-12-27
ZA987497B (en) 1999-02-23
HUP0004599A2 (hu) 2001-04-28
PL339259A1 (en) 2000-12-04
NZ502964A (en) 2001-08-31
TR200000618T2 (tr) 2000-09-21
AU746780B2 (en) 2002-05-02
AU9538198A (en) 1999-03-29
JP2001515721A (ja) 2001-09-25
NO20001178L (no) 2000-05-05
EP1012290A1 (en) 2000-06-28
WO1999013081A1 (en) 1999-03-18
HUP0004599A3 (en) 2002-09-30
CN1269834A (zh) 2000-10-11
NO20001178D0 (no) 2000-03-07
BR9812043A (pt) 2000-10-03
KR20010023749A (ko) 2001-03-26
IL134589A0 (en) 2001-04-30

Similar Documents

Publication Publication Date Title
JP6762916B2 (ja) アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ
EP1032688B1 (en) Single-chain bifunctional glycoprotein hormones
US20020160944A1 (en) Multifunctional single chain glycoprotein hormones
US11292824B2 (en) Pharmaceutical preparation comprising recombinant hCG
JPS62190084A (ja) ミュレル管抑制物質の活性を示すポリペプチドをコードするｄｎａ，組換ｄｎａおよび形質転換宿主
AU746780B2 (en) Expression of gonadotropins in dictyostelium
US7956034B2 (en) FSH glycosylation variant D3N
RU2668174C2 (ru) Суперагонисты гликопротеинового гормона длительного действия
IL192096A (en) Nucleic acid encoding fsh mutant, its preparation and pharmaceutical compositions containing it
ZA200601803B (en) FSH glycosylation mutant
RU2174407C2 (ru) Гонадотропины с ненативными дисульфидными мостиками
MXPA00002336A (en) Expression of gonadotropins in dictyostelium
CZ2000860A3 (cs) Gonadotropiny získané expresí v Dictyostelium
WO2002057443A1 (fr) Methode de production de ligand zaq
MXPA96005048A (en) Gonadotropinas with nonati disulfide bridges
MX2008009199A (en) Novel fsh glycosylation variant d3n

Legal Events

Date Code Title Description
FZDE Discontinued