CA2468048A1 - Procede de purification de rna synthetise par voie chimique - Google Patents

Procede de purification de rna synthetise par voie chimique Download PDF

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Publication number
CA2468048A1
CA2468048A1 CA002468048A CA2468048A CA2468048A1 CA 2468048 A1 CA2468048 A1 CA 2468048A1 CA 002468048 A CA002468048 A CA 002468048A CA 2468048 A CA2468048 A CA 2468048A CA 2468048 A1 CA2468048 A1 CA 2468048A1
Authority
CA
Canada
Prior art keywords
rna
ribozyme
ribozymes
column
eluate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002468048A
Other languages
English (en)
Inventor
Pamela Pavco
Leonid Beigelman
Bharat Chowrira
Anthony Direnzo
Anil Modak
Sean M. Sullivan
Kenneth G. Draper
David Sweedler
Francine E. Wincott
Tod Woolf
James A. Mcswiggen
Alexander Karpeisky
Susan Grimm
Lech W. Dudycz
Kevin Kisich
Jasenka Matulic-Adamic
Nassim Usman
James D. Thompson
Dan T. Stinchcomb
Danuta Tracz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sirna Therapeutics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/218,934 external-priority patent/US5639647A/en
Priority claimed from US08/291,932 external-priority patent/US5658780A/en
Priority claimed from US08/292,620 external-priority patent/US5837542A/en
Priority claimed from US08/311,486 external-priority patent/US5811300A/en
Priority claimed from US08/319,492 external-priority patent/US5616488A/en
Priority claimed from US08/321,993 external-priority patent/US5631359A/en
Priority claimed from US08/334,847 external-priority patent/US5693532A/en
Priority claimed from US08/337,608 external-priority patent/US5902880A/en
Priority claimed from US08/357,577 external-priority patent/US5783425A/en
Priority claimed from US08/363,233 external-priority patent/US5714383A/en
Application filed by Individual filed Critical Individual
Priority claimed from CA 2183992 external-priority patent/CA2183992A1/fr
Publication of CA2468048A1 publication Critical patent/CA2468048A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002468048A 1994-02-23 1995-02-23 Procede de purification de rna synthetise par voie chimique Abandoned CA2468048A1 (fr)

Applications Claiming Priority (53)

Application Number Priority Date Filing Date Title
US20110994A 1994-02-23 1994-02-23
US08/218,934 US5639647A (en) 1994-03-29 1994-03-29 2'-deoxy-2'alkylnucleotide containing nucleic acid
US22279594A 1994-04-04 1994-04-04
US22448394A 1994-04-07 1994-04-07
US08/224,483 1994-04-07
US22795894A 1994-04-15 1994-04-15
US22804194A 1994-04-15 1994-04-15
US24573694A 1994-05-18 1994-05-18
US27128094A 1994-07-06 1994-07-06
US08/291,932 US5658780A (en) 1992-12-07 1994-08-15 Rel a targeted ribozymes
US29143394A 1994-08-16 1994-08-16
US08/292,620 US5837542A (en) 1992-12-07 1994-08-17 Intercellular adhesion molecule-1 (ICAM-1) ribozymes
US29352094A 1994-08-19 1994-08-19
US30000094A 1994-09-02 1994-09-02
US30303994A 1994-09-08 1994-09-08
US08/303,039 1994-09-08
US31174994A 1994-09-23 1994-09-23
US08/311,486 US5811300A (en) 1992-12-07 1994-09-23 TNF-α ribozymes
US31439794A 1994-09-28 1994-09-28
US31677194A 1994-10-03 1994-10-03
US08/319,492 US5616488A (en) 1992-12-07 1994-10-07 IL-5 targeted ribozymes
US08/321,993 US5631359A (en) 1994-10-11 1994-10-11 Hairpin ribozymes
US08/334,847 US5693532A (en) 1994-11-04 1994-11-04 Respiratory syncytial virus ribozymes
US08/337,608 US5902880A (en) 1994-08-19 1994-11-10 RNA polymerase III-based expression of therapeutic RNAs
US33451694A 1994-11-28 1994-11-28
US08/334,516 1994-11-28
US08/357,577 US5783425A (en) 1993-10-27 1994-12-16 Amino and peptido modified enzymatic nucleic acid
US08/363,233 US5714383A (en) 1992-05-14 1994-12-23 Method and reagent for treating chronic myelogenous leukemia
US38073495A 1995-01-30 1995-01-30
US08/293,520 1995-01-30
US08/319,492 1995-01-30
US08/245,736 1995-01-30
US08/363,233 1995-01-30
US08/337,608 1995-01-30
US08/222,795 1995-01-30
US08/316,771 1995-01-30
US08/380,734 1995-01-30
US08/311,749 1995-01-30
US08/291,433 1995-01-30
US08/321,993 1995-01-30
US08/311,486 1995-01-30
US08/201,109 1995-01-30
US08/334,847 1995-01-30
US08/228,041 1995-01-30
US08/218,934 1995-01-30
US08/292,620 1995-01-30
US08/227,958 1995-01-30
US08/271,280 1995-01-30
US08/300,000 1995-01-30
US08/314,397 1995-01-30
US08/291,932 1995-01-30
US08/357,577 1995-01-30
CA 2183992 CA2183992A1 (fr) 1994-02-23 1995-02-23 Procede et reactif inhibiteur de l'expression de genes concernant une affection

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA 2183992 Division CA2183992A1 (fr) 1994-02-23 1995-02-23 Procede et reactif inhibiteur de l'expression de genes concernant une affection

Publications (1)

Publication Number Publication Date
CA2468048A1 true CA2468048A1 (fr) 1995-08-31

Family

ID=32660292

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002468048A Abandoned CA2468048A1 (fr) 1994-02-23 1995-02-23 Procede de purification de rna synthetise par voie chimique

Country Status (1)

Country Link
CA (1) CA2468048A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008077592A1 (fr) * 2006-12-22 2008-07-03 Curevac Gmbh Procédé de purification d'arn à l'échelle préparative par hplc
US10017826B2 (en) 2015-05-08 2018-07-10 Curevac Ag Method for producing RNA
US11667910B2 (en) 2015-05-29 2023-06-06 CureVac Manufacturing GmbH Method for producing and purifying RNA, comprising at least one step of tangential flow filtration

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008077592A1 (fr) * 2006-12-22 2008-07-03 Curevac Gmbh Procédé de purification d'arn à l'échelle préparative par hplc
US8383340B2 (en) 2006-12-22 2013-02-26 Curevac Gmbh Method for purifying RNA on a preparative scale by means of HPLC
US10017826B2 (en) 2015-05-08 2018-07-10 Curevac Ag Method for producing RNA
US10711315B2 (en) 2015-05-08 2020-07-14 Curevac Real Estate Gmbh Method for producing RNA
US11268157B2 (en) 2015-05-08 2022-03-08 Curevac Real Estate Gmbh Method for producing RNA
US11661634B2 (en) 2015-05-08 2023-05-30 CureVac Manufacturing GmbH Method for producing RNA
US11667910B2 (en) 2015-05-29 2023-06-06 CureVac Manufacturing GmbH Method for producing and purifying RNA, comprising at least one step of tangential flow filtration
US11760992B2 (en) 2015-05-29 2023-09-19 CureVac Manufacturing GmbH Method for producing and purifying RNA, comprising at least one step of tangential flow filtration
US11834651B2 (en) 2015-05-29 2023-12-05 CureVac Manufacturing GmbH Method for producing and purifying RNA, comprising at least one step of tangential flow filtration
US12221605B2 (en) 2015-05-29 2025-02-11 CureVac Manufacturing GmbH Method for producing and purifying RNA, comprising at least one step of tangential flow filtration

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead