CA2520400C - Traitement d'infections par aspergillus a l'aide de thymosine alpha 1 - Google Patents
Traitement d'infections par aspergillus a l'aide de thymosine alpha 1 Download PDFInfo
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- CA2520400C CA2520400C CA2520400A CA2520400A CA2520400C CA 2520400 C CA2520400 C CA 2520400C CA 2520400 A CA2520400 A CA 2520400A CA 2520400 A CA2520400 A CA 2520400A CA 2520400 C CA2520400 C CA 2520400C
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- aspergillus
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- dcs
- cells
- treatment
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2292—Thymosin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention concerne une méthode de traitement d'un être humain infecté par Aspergillus au moyen de thymosine alpha 1, en tant qu'immuno-stimulateur, dans l'activation de cellules dendritiques. Ladite méthode est, notamment, utilisée dans la prévention d'une infection par Aspergillus d'un hôte au système immunitaire compromis qui suit un traitement de transplantation de moelle osseuse.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45791103P | 2003-03-28 | 2003-03-28 | |
| US60/457,911 | 2003-03-28 | ||
| PCT/US2004/009550 WO2004087067A2 (fr) | 2003-03-28 | 2004-03-29 | Traitement d'infections par aspergillus a l'aide de thymosine alpha 1 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2520400A1 CA2520400A1 (fr) | 2004-10-14 |
| CA2520400C true CA2520400C (fr) | 2013-02-19 |
Family
ID=42828702
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2520400A Expired - Lifetime CA2520400C (fr) | 2003-03-28 | 2004-03-29 | Traitement d'infections par aspergillus a l'aide de thymosine alpha 1 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US8207294B2 (fr) |
| EP (1) | EP1613340B1 (fr) |
| JP (1) | JP4629033B2 (fr) |
| KR (1) | KR101089145B1 (fr) |
| AT (1) | ATE467422T1 (fr) |
| AU (1) | AU2004226403B2 (fr) |
| BR (1) | BRPI0408892A (fr) |
| CA (1) | CA2520400C (fr) |
| DK (1) | DK1613340T3 (fr) |
| EA (1) | EA008037B1 (fr) |
| IL (1) | IL171118A (fr) |
| MX (1) | MXPA05010391A (fr) |
| NO (1) | NO329997B1 (fr) |
| NZ (1) | NZ542900A (fr) |
| PL (1) | PL1613340T3 (fr) |
| UA (1) | UA80870C2 (fr) |
| WO (1) | WO2004087067A2 (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1613340T3 (da) | 2003-03-28 | 2010-08-30 | Sciclone Pharmaceuticals Inc | Behandling af aspergillus-infektioner med thymosin alfa 1 |
| MX2007006717A (es) * | 2004-12-06 | 2007-08-06 | Sciclone Pharmaceuticals Inc | Peptidos de alfa timocina como adyuvantes en vacunas contra el cancer. |
| JP2009537584A (ja) * | 2006-05-19 | 2009-10-29 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ | 免疫学的疾患の処置のためのチモシンα１の使用 |
| ITRM20060583A1 (it) * | 2006-10-27 | 2008-04-28 | Francesco Bistoni | Uso della timosina alfa 1 per la preparazione di un medicamento per la prevenzione e la cura delle allergie |
| US20140213506A1 (en) * | 2011-02-09 | 2014-07-31 | Cynthia W. TUTHILL | Thymosin alpha peptide for preventing, reducing the severity of, and treating infection |
| AU2016217473B2 (en) * | 2015-02-09 | 2021-07-29 | Sciclone Pharmaceuticals International (Sg) Pte. Ltd. | Thymosin alpha 1 for use in treatment of cystic fibrosis |
| ITUB20153714A1 (it) * | 2015-09-18 | 2017-03-18 | Luigina Romani | Timosina alfa 1 per l?uso nel trattamento della fibrosi cistica. |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4002740A (en) * | 1975-08-21 | 1977-01-11 | Gideon Goldstein | Tridecapeptide compositions and methods |
| US4079127A (en) * | 1976-10-28 | 1978-03-14 | Board Of Regents Of The University Of Texas | Thymosin alpha 1 |
| US4116951A (en) * | 1977-04-22 | 1978-09-26 | Hoffmann-La Roche Inc. | [Asn2 ]-thymosin α1 and analogs thereof |
| DE2919592A1 (de) * | 1979-05-15 | 1981-01-15 | Max Planck Gesellschaft | Verfahren zur herstellung von thymosin- alpha 1 und derivaten davon |
| US4612365A (en) * | 1980-03-25 | 1986-09-16 | Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften | Medicaments containing alpha 1-thymosin and having an immuno regulatory action and alpha 1-thymosin fragments |
| US4374197A (en) * | 1980-10-30 | 1983-02-15 | Hoffmann-La Rocche Inc. | Process for thymosin α1 |
| TW224053B (fr) | 1991-09-13 | 1994-05-21 | Paul B Chretien | |
| CN1058500C (zh) * | 1993-02-03 | 2000-11-15 | 施塞克龙药品公司 | 胸腺素α－1衍生物 |
| CN1072961C (zh) | 1993-03-05 | 2001-10-17 | 施塞克龙药品公司 | 治疗对干扰素治疗无反应者的丙型肝炎的方法 |
| TW252045B (fr) * | 1993-10-07 | 1995-07-21 | Allan L Goldstein | |
| RU2107692C1 (ru) * | 1995-06-07 | 1998-03-27 | Дейгин Владислав Исакович | Пептид и способ его получения |
| US5888980A (en) * | 1994-06-30 | 1999-03-30 | Bio-Logic Research And Development Corporation | Compositions for enhancing immune function |
| US5632983A (en) | 1994-11-17 | 1997-05-27 | University Of South Florida | Method for treating secondary immunodeficiency |
| WO1998035696A1 (fr) * | 1997-02-18 | 1998-08-20 | Sciclone Pharmaceuticals, Inc. | Utilisation de thymosine alpha 1 pour la fabrication d'un medicament destine a favoriser le developpement de cellules souches |
| UA80957C2 (en) * | 2001-11-01 | 2007-11-26 | Sciclone Pharmaceuticals Inc | Method of administering a thymosin alpha 1 peptide |
| DK1613340T3 (da) | 2003-03-28 | 2010-08-30 | Sciclone Pharmaceuticals Inc | Behandling af aspergillus-infektioner med thymosin alfa 1 |
-
2004
- 2004-03-29 DK DK04749495.0T patent/DK1613340T3/da active
- 2004-03-29 EP EP04749495A patent/EP1613340B1/fr not_active Expired - Lifetime
- 2004-03-29 NZ NZ542900A patent/NZ542900A/en not_active IP Right Cessation
- 2004-03-29 BR BRPI0408892-1A patent/BRPI0408892A/pt not_active IP Right Cessation
- 2004-03-29 EA EA200501414A patent/EA008037B1/ru not_active IP Right Cessation
- 2004-03-29 UA UAA200509921A patent/UA80870C2/xx unknown
- 2004-03-29 CA CA2520400A patent/CA2520400C/fr not_active Expired - Lifetime
- 2004-03-29 AU AU2004226403A patent/AU2004226403B2/en not_active Ceased
- 2004-03-29 WO PCT/US2004/009550 patent/WO2004087067A2/fr not_active Ceased
- 2004-03-29 KR KR1020057018335A patent/KR101089145B1/ko not_active Expired - Fee Related
- 2004-03-29 AT AT04749495T patent/ATE467422T1/de active
- 2004-03-29 PL PL04749495T patent/PL1613340T3/pl unknown
- 2004-03-29 US US10/551,341 patent/US8207294B2/en active Active
- 2004-03-29 JP JP2006509423A patent/JP4629033B2/ja not_active Expired - Lifetime
- 2004-03-29 MX MXPA05010391A patent/MXPA05010391A/es active IP Right Grant
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2005
- 2005-09-27 IL IL171118A patent/IL171118A/en not_active IP Right Cessation
- 2005-10-24 NO NO20054912A patent/NO329997B1/no not_active IP Right Cessation
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2012
- 2012-05-29 US US13/482,978 patent/US8389680B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004087067A3 (fr) | 2004-12-29 |
| UA80870C2 (en) | 2007-11-12 |
| AU2004226403B2 (en) | 2008-12-04 |
| MXPA05010391A (es) | 2005-11-04 |
| EP1613340A4 (fr) | 2009-07-01 |
| KR20050114264A (ko) | 2005-12-05 |
| NO20054912D0 (no) | 2005-10-24 |
| DK1613340T3 (da) | 2010-08-30 |
| EP1613340B1 (fr) | 2010-05-12 |
| ATE467422T1 (de) | 2010-05-15 |
| IL171118A (en) | 2011-10-31 |
| KR101089145B1 (ko) | 2011-12-02 |
| US20120295840A1 (en) | 2012-11-22 |
| AU2004226403A1 (en) | 2004-10-14 |
| NO20054912L (no) | 2005-12-20 |
| CA2520400A1 (fr) | 2004-10-14 |
| US8207294B2 (en) | 2012-06-26 |
| NZ542900A (en) | 2007-06-29 |
| EP1613340A2 (fr) | 2006-01-11 |
| BRPI0408892A (pt) | 2006-04-11 |
| PL1613340T3 (pl) | 2010-10-29 |
| US20070129292A1 (en) | 2007-06-07 |
| US8389680B2 (en) | 2013-03-05 |
| NO329997B1 (no) | 2011-02-07 |
| WO2004087067A2 (fr) | 2004-10-14 |
| JP4629033B2 (ja) | 2011-02-09 |
| EA200501414A1 (ru) | 2006-04-28 |
| JP2006521406A (ja) | 2006-09-21 |
| EA008037B1 (ru) | 2007-02-27 |
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