CA2651002A1 - Use of escitalopram for improving cognition - Google Patents
Use of escitalopram for improving cognition Download PDFInfo
- Publication number
- CA2651002A1 CA2651002A1 CA002651002A CA2651002A CA2651002A1 CA 2651002 A1 CA2651002 A1 CA 2651002A1 CA 002651002 A CA002651002 A CA 002651002A CA 2651002 A CA2651002 A CA 2651002A CA 2651002 A1 CA2651002 A1 CA 2651002A1
- Authority
- CA
- Canada
- Prior art keywords
- condition
- use according
- escitalopram
- medicament
- unit dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- WSEQXVZVJXJVFP-FQEVSTJZSA-N escitalopram Chemical compound C1([C@]2(C3=CC=C(C=C3CO2)C#N)CCCN(C)C)=CC=C(F)C=C1 WSEQXVZVJXJVFP-FQEVSTJZSA-N 0.000 title claims abstract description 69
- 229960004341 escitalopram Drugs 0.000 title claims abstract description 67
- 230000019771 cognition Effects 0.000 title claims abstract description 50
- 239000003814 drug Substances 0.000 claims abstract description 26
- 230000003292 diminished effect Effects 0.000 claims abstract description 25
- 238000002360 preparation method Methods 0.000 claims abstract description 23
- 150000001875 compounds Chemical class 0.000 claims abstract description 22
- 150000003839 salts Chemical class 0.000 claims abstract description 21
- 238000011282 treatment Methods 0.000 claims description 22
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- 239000000164 antipsychotic agent Substances 0.000 claims description 12
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- 230000000561 anti-psychotic effect Effects 0.000 claims description 11
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- PMXMIIMHBWHSKN-UHFFFAOYSA-N 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one Chemical compound FC1=CC=C2C(C3CCN(CC3)CCC=3C(=O)N4CCCC(O)C4=NC=3C)=NOC2=C1 PMXMIIMHBWHSKN-UHFFFAOYSA-N 0.000 claims description 6
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- PXUIZULXJVRBPC-UHFFFAOYSA-N 1'-[3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]hexahydro-2H-spiro[imidazo[1,2-a]pyridine-3,4'-piperidin]-2-one Chemical compound C12=CC(Cl)=CC=C2CCC2=CC=CC=C2N1CCCN1CCC2(C(NC3CCCCN32)=O)CC1 PXUIZULXJVRBPC-UHFFFAOYSA-N 0.000 claims description 5
- DKMFBWQBDIGMHM-UHFFFAOYSA-N 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone Chemical compound C1CC(C)CCN1CCCC(=O)C1=CC=C(F)C=C1 DKMFBWQBDIGMHM-UHFFFAOYSA-N 0.000 claims description 5
- MDLAAYDRRZXJIF-UHFFFAOYSA-N 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol Chemical compound C1CC(O)(C=2C=C(C(Cl)=CC=2)C(F)(F)F)CCN1CCCC(C=1C=CC(F)=CC=1)C1=CC=C(F)C=C1 MDLAAYDRRZXJIF-UHFFFAOYSA-N 0.000 claims description 5
- FEBOTPHFXYHVPL-UHFFFAOYSA-N 3-[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1H-benzimidazol-2-one Chemical compound C1=CC(F)=CC=C1C(=O)CCCN1CCC(N2C(NC3=CC=CC=C32)=O)CC1 FEBOTPHFXYHVPL-UHFFFAOYSA-N 0.000 claims description 5
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- ILMHNKKMKWQVCE-UHFFFAOYSA-N 8-fluoro-12-(4-methylpiperazin-1-yl)-6h-[1]benzothiolo[2,3-b][1,5]benzodiazepine Chemical compound C1CN(C)CCN1C1=NC2=CC=C(F)C=C2NC2=C1C1=CC=CC=C1S2 ILMHNKKMKWQVCE-UHFFFAOYSA-N 0.000 claims description 5
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- RKLNONIVDFXQRX-UHFFFAOYSA-N Bromperidol Chemical compound C1CC(O)(C=2C=CC(Br)=CC=2)CCN1CCCC(=O)C1=CC=C(F)C=C1 RKLNONIVDFXQRX-UHFFFAOYSA-N 0.000 claims description 5
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- JNNOSTQEZICQQP-UHFFFAOYSA-N N-desmethylclozapine Chemical compound N=1C2=CC(Cl)=CC=C2NC2=CC=CC=C2C=1N1CCNCC1 JNNOSTQEZICQQP-UHFFFAOYSA-N 0.000 claims description 5
- XCWPUUGSGHNIDZ-UHFFFAOYSA-N Oxypertine Chemical compound C1=2C=C(OC)C(OC)=CC=2NC(C)=C1CCN(CC1)CCN1C1=CC=CC=C1 XCWPUUGSGHNIDZ-UHFFFAOYSA-N 0.000 claims description 5
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- ZGUGWUXLJSTTMA-UHFFFAOYSA-N Promazinum Chemical compound C1=CC=C2N(CCCN(C)C)C3=CC=CC=C3SC2=C1 ZGUGWUXLJSTTMA-UHFFFAOYSA-N 0.000 claims description 5
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- Psychology (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200600621 | 2006-05-02 | ||
| DKPA200600621 | 2006-05-02 | ||
| PCT/DK2007/050050 WO2007124757A2 (en) | 2006-05-02 | 2007-04-30 | Use of escitalopram for improving cognition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2651002A1 true CA2651002A1 (en) | 2007-11-08 |
Family
ID=38134951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002651002A Abandoned CA2651002A1 (en) | 2006-05-02 | 2007-04-30 | Use of escitalopram for improving cognition |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP2026793A2 (pt) |
| JP (1) | JP2009535367A (pt) |
| KR (1) | KR20090009820A (pt) |
| CN (1) | CN101426494A (pt) |
| AR (1) | AR060732A1 (pt) |
| AU (1) | AU2007245983A1 (pt) |
| BR (1) | BRPI0710230A2 (pt) |
| CA (1) | CA2651002A1 (pt) |
| EA (1) | EA200870491A1 (pt) |
| IL (1) | IL194628A0 (pt) |
| MX (1) | MX2008013911A (pt) |
| NO (1) | NO20085009L (pt) |
| TW (1) | TW200812993A (pt) |
| WO (1) | WO2007124757A2 (pt) |
| ZA (1) | ZA200808632B (pt) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1535616B1 (en) | 2002-08-22 | 2009-05-13 | Dainippon Sumitomo Pharma Co., Ltd. | Remedy for integration dysfunction syndrome |
| KR101113630B1 (ko) | 2003-06-23 | 2012-02-13 | 다이닛본 스미토모 세이야꾸 가부시끼가이샤 | 노인성 치매 치료제 |
| US20070160537A1 (en) | 2004-02-20 | 2007-07-12 | Takeo Ishiyama | In vivo screening method of therapeutic agent for memory/learning dysfunctions by schizophrenia |
| US20090036468A1 (en) * | 2007-08-03 | 2009-02-05 | Forest Laboratories Holdings Limited | Pharmaceutical compositions containing dopamine receptor ligands and methods of treatment using dopamine receptor ligands |
| EP2236138A1 (en) * | 2009-03-30 | 2010-10-06 | PharmaNeuroBoost N.V. | Low dose pipamperone in treating mood and anxiety disorders |
| US8258139B2 (en) * | 2010-11-08 | 2012-09-04 | Dainippon Sumitomo Pharma Co., Ltd. | Method of treatment for mental disorders |
| EP3069718A1 (en) * | 2015-03-17 | 2016-09-21 | Universidade do Minho | Citalopram or escitalopram for use in the treatment of neurodegenerative diseases |
| CN115813888A (zh) | 2016-12-20 | 2023-03-21 | 罗曼治疗系统股份公司 | 包含阿塞那平的透皮治疗系统 |
| EP3558276B1 (en) | 2016-12-20 | 2024-11-06 | LTS Lohmann Therapie-Systeme AG | Transdermal therapeutic system containing asenapine and polysiloxane or polyisobutylene |
| WO2019002204A1 (en) | 2017-06-26 | 2019-01-03 | Lts Lohmann Therapie-Systeme Ag | TRANSDERMAL THERAPEUTIC SYSTEM CONTAINING ASENAPINE AND SILICONE-TYPE ACRYLIC HYBRID POLYMER |
| AU2019291060B2 (en) | 2018-06-20 | 2024-09-05 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
| US12329862B2 (en) | 2018-06-20 | 2025-06-17 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
| KR102051624B1 (ko) * | 2018-11-30 | 2019-12-02 | 아밀로이드솔루션 주식회사 | 트리플루프로마진 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 퇴행성 뇌질환 치료용 약학 조성물 |
| CN109464436A (zh) * | 2019-01-10 | 2019-03-15 | 高智玉 | 西酞普兰或艾司西酞普兰分别和喹硫平联合在制备治疗精神障碍类疾病的复方制剂中的应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK213290D0 (da) * | 1990-09-06 | 1990-09-06 | Lundbeck & Co As H | Treatment of cerebrovascular disorders |
| SE9803157D0 (sv) * | 1998-09-16 | 1998-09-16 | Astra Ab | A new composition |
| SE9803158D0 (sv) * | 1998-09-16 | 1998-09-16 | Astra Ab | A new composition |
| US6617361B2 (en) * | 1999-11-05 | 2003-09-09 | Be Able, Llc | Behavior chemotherapy |
| ATE329620T1 (de) * | 2000-12-01 | 2006-07-15 | Be Able Llc | Verhaltenchemotherapie |
| WO2002076461A1 (en) * | 2001-03-26 | 2002-10-03 | Serdar Murat Dursun | Combination of reboxetine and citalopram |
| WO2002087566A1 (en) * | 2001-05-01 | 2002-11-07 | H. Lundbeck A/S | The use of enantiomeric pure escitalopram |
| US20050014848A1 (en) * | 2002-01-23 | 2005-01-20 | Pfizer Inc. | Combination of serotonin reuptake inhibitors and norephinephrine reuptake inhibitors |
| CA2529857A1 (en) * | 2002-07-30 | 2004-02-05 | Peter Migaly | Combination therapy for depression, prevention of suicide, and varous medical and psychiatric conditions |
| AU2003287919B2 (en) * | 2002-12-23 | 2009-11-12 | H. Lundbeck A/S | Escitalopram hydrobromide and a method for the preparation thereof |
| WO2005023243A1 (en) * | 2003-09-04 | 2005-03-17 | H. Lundbeck A/S | The combination of a serotonin reuptake inhibitor and loxapine |
| JP2009511607A (ja) * | 2005-10-14 | 2009-03-19 | ハー・ルンドベック・アクチエゼルスカベット | エスシタロプラムおよびブプロピオンを含有する安定な医薬製剤 |
| EA200801081A1 (ru) * | 2005-10-14 | 2008-10-30 | Х. Лундбекк А/С | Способы лечения расстройств центральной нервной системы комбинацией малых доз эсциталопрама и бупропиона |
| US20070134322A1 (en) * | 2005-12-14 | 2007-06-14 | Forest Laboratories, Inc. | Modified and pulsatile release pharmaceutical formulations of escitalopram |
-
2007
- 2007-04-25 TW TW096114520A patent/TW200812993A/zh unknown
- 2007-04-30 KR KR1020087025797A patent/KR20090009820A/ko not_active Withdrawn
- 2007-04-30 AR ARP070101874A patent/AR060732A1/es unknown
- 2007-04-30 MX MX2008013911A patent/MX2008013911A/es not_active Application Discontinuation
- 2007-04-30 CN CNA200780014675XA patent/CN101426494A/zh active Pending
- 2007-04-30 AU AU2007245983A patent/AU2007245983A1/en not_active Abandoned
- 2007-04-30 JP JP2009508134A patent/JP2009535367A/ja not_active Withdrawn
- 2007-04-30 BR BRPI0710230-5A patent/BRPI0710230A2/pt not_active IP Right Cessation
- 2007-04-30 EA EA200870491A patent/EA200870491A1/ru unknown
- 2007-04-30 WO PCT/DK2007/050050 patent/WO2007124757A2/en not_active Ceased
- 2007-04-30 EP EP07722705A patent/EP2026793A2/en not_active Withdrawn
- 2007-04-30 CA CA002651002A patent/CA2651002A1/en not_active Abandoned
-
2008
- 2008-10-07 IL IL194628A patent/IL194628A0/en unknown
- 2008-10-09 ZA ZA2008/08632A patent/ZA200808632B/en unknown
- 2008-12-02 NO NO20085009A patent/NO20085009L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101426494A (zh) | 2009-05-06 |
| IL194628A0 (en) | 2009-08-03 |
| KR20090009820A (ko) | 2009-01-23 |
| AR060732A1 (es) | 2008-07-10 |
| TW200812993A (en) | 2008-03-16 |
| ZA200808632B (en) | 2009-12-30 |
| AU2007245983A1 (en) | 2007-11-08 |
| WO2007124757A3 (en) | 2008-07-24 |
| JP2009535367A (ja) | 2009-10-01 |
| WO2007124757A2 (en) | 2007-11-08 |
| EP2026793A2 (en) | 2009-02-25 |
| MX2008013911A (es) | 2008-11-12 |
| BRPI0710230A2 (pt) | 2011-08-02 |
| EA200870491A1 (ru) | 2009-04-28 |
| NO20085009L (no) | 2008-12-16 |
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Legal Events
| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Discontinued |