CA2853258A1 - Immunobinders directed against sclerostin - Google Patents

Immunobinders directed against sclerostin Download PDF

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Publication number
CA2853258A1
CA2853258A1 CA2853258A CA2853258A CA2853258A1 CA 2853258 A1 CA2853258 A1 CA 2853258A1 CA 2853258 A CA2853258 A CA 2853258A CA 2853258 A CA2853258 A CA 2853258A CA 2853258 A1 CA2853258 A1 CA 2853258A1
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CA
Canada
Prior art keywords
seq
residues
binding protein
sclerostin
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2853258A
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English (en)
French (fr)
Inventor
Chung-Ming Hsieh
Alexander Ivanov
Wendy Waegell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AbbVie Inc
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AbbVie Inc
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Filing date
Publication date
Application filed by AbbVie Inc filed Critical AbbVie Inc
Publication of CA2853258A1 publication Critical patent/CA2853258A1/en
Abandoned legal-status Critical Current

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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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AR088513A1 (es) 2014-06-18
US8999331B2 (en) 2015-04-07
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UY34411A (es) 2013-05-31
JP2014533659A (ja) 2014-12-15
US20130171096A1 (en) 2013-07-04
MX2014004977A (es) 2014-09-11
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EP2771360A1 (en) 2014-09-03
CN104203978A (zh) 2014-12-10

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