CH149012A - Process for the preparation of an N-substituted compound of the pyridone series. - Google Patents

Process for the preparation of an N-substituted compound of the pyridone series.

Info

Publication number
CH149012A
CH149012A CH149012DA CH149012A CH 149012 A CH149012 A CH 149012A CH 149012D A CH149012D A CH 149012DA CH 149012 A CH149012 A CH 149012A
Authority
CH
Switzerland
Prior art keywords
preparation
substituted compound
pyridone series
series
pyridone
Prior art date
Application number
Other languages
German (de)
Inventor
Gesellschaft Fuer Chemis Basel
Original Assignee
Chem Ind Basel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Ind Basel filed Critical Chem Ind Basel
Publication of CH149012A publication Critical patent/CH149012A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Description

  

  Verfahren zur Darstellung einer     N-substituierten    Verbindung der     Psridonreihe.       Es wurde gefunden, dass man zu einer       N-substituierten    Verbindung     der\Pyridonreihe          gelangen    kann, wenn man     2-Piperidinoäthoxy-          pyi-idin-3-carborisäureariilid    durch Erwärmen  umlagert.  



  Das entstandene     N-Piperidinoäthyl-2-pyri-          dori-3-carbonsäureariilid    ist in organischen  Lösungsmitteln, sowie in Säuren löslich. Das  farblose     11I'        onochlorhydrat    schmilzt bei<B>215".</B>  



  Die neue Base soll für therapeutische  Zwecke Verwendung finden.  



  <I>Beispiel:</I>       2-Piperidirioäthoxypyridin-3-carbonsäure-          anilid    wird durch Erhitzen auf etwa 220-270    umgelagert.



  Process for the preparation of an N-substituted compound of the psridone series. It has been found that an N-substituted compound of the pyridone series can be obtained if 2-piperidinoethoxypyi-idin-3-carboric acid ailide is rearranged by heating.



  The resulting N-piperidinoethyl-2-pyridori-3-carboxylic acid arylide is soluble in organic solvents and acids. The colorless 11I'onochlorohydrate melts at <B> 215 ". </B>



  The new base will be used for therapeutic purposes.



  <I> Example: </I> 2-piperidirioethoxypyridine-3-carboxylic acid anilide is rearranged to about 220-270 when heated.

Claims (1)

<B>PATENTANSPRUCH:</B> Verfahren zur Darstellung einer N-snbsti- tuierten Verbindung der Pyridonreihe, dadurch gekennzeichnet, dass man 2-Piperidinoätboxy- pyridin-3-carbonsäureanilid durch Erwärmen umlagert. Das entstandene N-Piperidiiioäthyl-2-pyri- dori-3-carbonsäureanilid ist in organischen Lösungsmitteln, sowie in Säuren löslieh. Das farblose lyIonochlorhydrat schmilzt bei<B>215</B> . Die neue Base soll für therapeutische Zwecke Verwendung finden. Claim: Process for the preparation of an N-substituted compound of the pyridone series, characterized in that 2-piperidinoätboxy-pyridine-3-carboxylic anilide is rearranged by heating. The resulting N-piperidiiioäthyl-2-pyridori-3-carboxylic acid anilide is soluble in organic solvents and acids. The colorless lyionochlorohydrate melts at <B> 215 </B>. The new base will be used for therapeutic purposes.
CH149012D 1929-08-10 1929-08-10 Process for the preparation of an N-substituted compound of the pyridone series. CH149012A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH149012T 1929-08-10
CH146709T 1929-08-10

Publications (1)

Publication Number Publication Date
CH149012A true CH149012A (en) 1931-08-15

Family

ID=25714915

Family Applications (1)

Application Number Title Priority Date Filing Date
CH149012D CH149012A (en) 1929-08-10 1929-08-10 Process for the preparation of an N-substituted compound of the pyridone series.

Country Status (1)

Country Link
CH (1) CH149012A (en)

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