CH201873A - Process for the preparation of 3,6-diamino-10-methylacridinium acetate. - Google Patents

Process for the preparation of 3,6-diamino-10-methylacridinium acetate.

Info

Publication number
CH201873A
CH201873A CH201873DA CH201873A CH 201873 A CH201873 A CH 201873A CH 201873D A CH201873D A CH 201873DA CH 201873 A CH201873 A CH 201873A
Authority
CH
Switzerland
Prior art keywords
sep
diamino
methylacridinium
acetate
preparation
Prior art date
Application number
Other languages
German (de)
Inventor
Aktiengesellsc Farbenindustrie
Original Assignee
Ig Farbenindustrie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ig Farbenindustrie Ag filed Critical Ig Farbenindustrie Ag
Publication of CH201873A publication Critical patent/CH201873A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

  

  Verfahren zur     llersteltung    von     3,6-Diamino-10-methylacridiniumacetat.       Die     vorliegende        Erfindung        bezieht    sich  auf     ein.    Verfahren zur Herstellung von     3,6-          Diamino-10-methylacri-diniumacetat,    welches       daiduroh        gekennzeichnet    ist,     dass,    man die  <B>,</B>     J,

          6-        Dia        mino@-10    -     mathylacridiniumacetonver-          bindung    in     wässriger    Lösung mit     Acetamid     erhitzt.  



       Das    so     erhältliche        3,6-Diamino-10-m-ethyl-          a.cri@diniumacetat    stellt eine neue     -#Tarbindung     dar, ,die nachdem     Eindampfen    und Ausfällen  ein rotbraunes Pulver     bildet,    das in Äther,  Benzol und     Chloroform        unlöslich,    in Aceton  schwer löslich und     in    Äthanol, Methanol und  Wasser leicht löslich ist; sie soll für pharma  zeutische Zwecke     Verwendung    finden.

    
EMI0001.0031     
  
    <I>Beispiel:</I>     
EMI0001.0032     
  
    1:40 <SEP> #g <SEP> 3;6-Diamino-10-m-ethylacri.dinium  acetonverbindung <SEP> werden, <SEP> mit <SEP> 2 <SEP> Liter <SEP> Wasser
<tb>  und <SEP> 3,0 <SEP> .g <SEP> Acetamid <SEP> 5 <SEP> .Stunden <SEP> auf <SEP> dem
<tb>  Wasserbad <SEP> erwärmt. <SEP> Unter <SEP> Entwicklung <SEP> von     
EMI0001.0033     
  
    Aceton <SEP> und <SEP> Ammoniak <SEP> ,geht <SEP> alles <SEP> in <SEP> Lösung.
<tb>  Man <SEP> dampft <SEP> fast <SEP> zur <SEP> Trockne <SEP> und <SEP> fällt <SEP> :das
<tb>  3,6-Diamino <SEP> 1,0-methylaeridiniumacetat <SEP> mit  tels <SEP> Aoeton <SEP> als <SEP> rotbraunes <SEP> Pulver.



  Process for the preparation of 3,6-diamino-10-methylacridinium acetate. The present invention relates to a. Process for the preparation of 3,6-diamino-10-methylacri-dinium acetate, which is characterized daiduroh that, one the <B>, </B> J,

          6- Dia mino @ -10 - mathylacridinium acetone compound in aqueous solution heated with acetamide.



       The 3,6-diamino-10-m-ethyl-a.cri@diniumacetat available in this way represents a new - # Tarbünden, which after evaporation and precipitation forms a red-brown powder that is insoluble in ether, benzene and chloroform, in acetone sparingly soluble and easily soluble in ethanol, methanol and water; it should be used for pharmaceutical purposes.

    
EMI0001.0031
  
    <I> Example: </I>
EMI0001.0032
  
    1:40 <SEP> #g <SEP> 3; 6-Diamino-10-m-ethylacri.dinium acetone compound <SEP>, <SEP> with <SEP> 2 <SEP> liters of <SEP> water
<tb> and <SEP> 3.0 <SEP> .g <SEP> Acetamide <SEP> 5 <SEP> .hours <SEP> on <SEP> dem
<tb> Water bath <SEP> heated. <SEP> Under <SEP> development <SEP> from
EMI0001.0033
  
    Acetone <SEP> and <SEP> ammonia <SEP>, <SEP> everything goes <SEP> in <SEP> solution.
<tb> Man <SEP> steams <SEP> almost <SEP> to the <SEP> dryness <SEP> and <SEP> falls <SEP>: that
<tb> 3,6-Diamino <SEP> 1,0-methylaeridinium acetate <SEP> with <SEP> Aoeton <SEP> as <SEP> red-brown <SEP> powder.

Claims (1)

PATENTANSPRUCH: EMI0001.0034 Verfahren <SEP> zur <SEP> Herstellung <SEP> von <SEP> 3-,6-Di amino-10-methylacridiniumacetat, <SEP> dadurch <tb> gekennzeichnet,,dass <SEP> man <SEP> 3;6-Diamino-10-me thylacridiniumacetonverbiudung <SEP> in <SEP> wässriger <tb> Lösung <SEP> mit <SEP> Acetamid <SEP> erhitzt. <tb> Die <SEP> neue <SEP> Verbindung <SEP> stellt <SEP> ein <SEP> rotbraun <tb> Pulver <SEP> dar; <SEP> das <SEP> in. <SEP> Äther, <SEP> Benzol <SEP> und <SEP> Chloro form <SEP> unlöslich, <SEP> in <SEP> Aceton <SEP> schwer <SEP> löslioh <SEP> und <tb> in <SEP> Äthanol, <SEP> Methanol <SEP> und <SEP> Wasser <SEP> leicht <SEP> lös lich <SEP> ist; <SEP> sie <SEP> soll <SEP> für <SEP> pharmazeutische <SEP> Zwecke <tb> Verwendung <SEP> finden. PATENT CLAIM: EMI0001.0034 Method <SEP> for <SEP> production <SEP> of <SEP> 3-, 6-diamino-10-methylacridinium acetate, <SEP> thereby <tb> marked, that <SEP> one <SEP> 3; 6-diamino-10-methylacridinium acetone compound <SEP> in <SEP> aqueous <tb> Solution <SEP> heated with <SEP> acetamide <SEP>. <tb> The <SEP> new <SEP> connection <SEP> sets <SEP> to <SEP> red-brown <tb> powder <SEP> represents; <SEP> the <SEP> in. <SEP> ether, <SEP> benzene <SEP> and <SEP> chloroform <SEP> insoluble, <SEP> in <SEP> acetone <SEP> poorly <SEP> soluble <SEP > and <tb> in <SEP> ethanol, <SEP> methanol <SEP> and <SEP> water <SEP> is slightly <SEP> soluble <SEP>; <SEP> you <SEP> should <SEP> for <SEP> pharmaceutical <SEP> purposes <tb> Find use <SEP>.
CH201873D 1935-04-20 1936-04-18 Process for the preparation of 3,6-diamino-10-methylacridinium acetate. CH201873A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE201873X 1935-04-20
CH197431T 1936-04-18

Publications (1)

Publication Number Publication Date
CH201873A true CH201873A (en) 1938-12-15

Family

ID=25722989

Family Applications (1)

Application Number Title Priority Date Filing Date
CH201873D CH201873A (en) 1935-04-20 1936-04-18 Process for the preparation of 3,6-diamino-10-methylacridinium acetate.

Country Status (1)

Country Link
CH (1) CH201873A (en)

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