CH558374A - Verfahren zur herstellung von arylsubstituierten piperazinylalkyl- bezw. alkenyl- chinazolon-(4)-derivaten. - Google Patents

Verfahren zur herstellung von arylsubstituierten piperazinylalkyl- bezw. alkenyl- chinazolon-(4)-derivaten.

Info

Publication number
CH558374A
CH558374A CH450074A CH450074A CH558374A CH 558374 A CH558374 A CH 558374A CH 450074 A CH450074 A CH 450074A CH 450074 A CH450074 A CH 450074A CH 558374 A CH558374 A CH 558374A
Authority
CH
Switzerland
Prior art keywords
chinazolone
alkenyl
aryl
derivatives
production
Prior art date
Application number
CH450074A
Other languages
German (de)
English (en)
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of CH558374A publication Critical patent/CH558374A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH450074A 1970-06-05 1971-06-02 Verfahren zur herstellung von arylsubstituierten piperazinylalkyl- bezw. alkenyl- chinazolon-(4)-derivaten. CH558374A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702027645 DE2027645A1 (de) 1970-06-05 1970-06-05 Piperazinylalkyl chinazolon (4) den vate, Verfahren zu deren Herstellung und sie enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
CH558374A true CH558374A (de) 1975-01-31

Family

ID=5773104

Family Applications (3)

Application Number Title Priority Date Filing Date
CH450074A CH558374A (de) 1970-06-05 1971-06-02 Verfahren zur herstellung von arylsubstituierten piperazinylalkyl- bezw. alkenyl- chinazolon-(4)-derivaten.
CH450174A CH569732A5 (2) 1970-06-05 1971-06-02
CH802071A CH557829A (de) 1970-06-05 1971-06-02 Verfahren zur herstellung von arylsubstituierten piperazinyl-alkyl- bzw. -alkenyl-chinazolon-(4)-derivaten.

Family Applications After (2)

Application Number Title Priority Date Filing Date
CH450174A CH569732A5 (2) 1970-06-05 1971-06-02
CH802071A CH557829A (de) 1970-06-05 1971-06-02 Verfahren zur herstellung von arylsubstituierten piperazinyl-alkyl- bzw. -alkenyl-chinazolon-(4)-derivaten.

Country Status (10)

Country Link
US (1) US3984555A (2)
AT (3) AT318628B (2)
BE (1) BE768137A (2)
CA (1) CA951319A (2)
CH (3) CH558374A (2)
DE (1) DE2027645A1 (2)
FR (1) FR2100726B1 (2)
GB (1) GB1331522A (2)
LU (1) LU63267A1 (2)
NL (1) NL7107695A (2)

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US4287341A (en) * 1979-11-01 1981-09-01 Pfizer Inc. Alkoxy-substituted-6-chloro-quinazoline-2,4-diones
US6723727B1 (en) * 1996-12-20 2004-04-20 Hoechst Aktiengesellschaft Substituted purine derivatives, processes for their preparation, their use, and compositions comprising them
EP0903344B1 (en) * 1997-08-21 2011-01-26 Shiseido Co., Ltd. Quinazolin-4-one derivatives, their preparation and their use as hair growth promoters or in external compositions for skin
US6355637B1 (en) 1999-10-01 2002-03-12 Advanced Medicine, Inc. Local anesthetic compounds
GEP20084317B (en) 2000-04-25 2008-02-25 Icos Corp Inhibitors of human phosphatidyl-inositol 3-kinase delta
US6667300B2 (en) * 2000-04-25 2003-12-23 Icos Corporation Inhibitors of human phosphatidylinositol 3-kinase delta
AUPR201600A0 (en) * 2000-12-11 2001-01-11 Fujisawa Pharmaceutical Co., Ltd. Quinazolinone derivative
EP2329822A1 (en) 2001-09-05 2011-06-08 Minerva Biotechnologies Corporation Compositions and methods of treatment of cancer
WO2003020280A2 (en) * 2001-09-05 2003-03-13 Minerva Biotechnologies Corporation Compositions and use thereof in the treatment of cancer
JP2005511581A (ja) * 2001-11-07 2005-04-28 メルク　エンド　カムパニー　インコーポレーテッド 有糸分裂キネシン阻害剤
AUPS019702A0 (en) * 2002-01-29 2002-02-21 Fujisawa Pharmaceutical Co., Ltd. Condensed heterocyclic compounds
WO2004018058A2 (en) * 2002-08-21 2004-03-04 Cytokinetics, Inc. Compounds, compositions, and methods
MXPA05004328A (es) * 2002-11-04 2005-08-02 Nps Pharma Inc Compuestos de quinazolinona como calciliticos.
EP1646615B1 (en) * 2003-06-06 2009-08-26 Vertex Pharmaceuticals Incorporated Pyrimidine derivatives as modulators of atp-binding cassette transporters
WO2005016348A1 (en) * 2003-08-14 2005-02-24 Icos Corporation Method of inhibiting immune responses stimulated by an endogenous factor
US20050054614A1 (en) * 2003-08-14 2005-03-10 Diacovo Thomas G. Methods of inhibiting leukocyte accumulation
WO2005113556A1 (en) 2004-05-13 2005-12-01 Icos Corporation Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
WO2005117889A1 (en) * 2004-05-25 2005-12-15 Icos Corporation Methods for treating and/or preventing aberrant proliferation of hematopoietic
WO2006089106A2 (en) * 2005-02-17 2006-08-24 Icos Corporation Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
EP2010505B1 (en) * 2006-03-28 2012-12-05 Atir Holding S.A. Heterocyclic compounds and uses thereof in the treatment of sexual disorders
US9492449B2 (en) 2008-11-13 2016-11-15 Gilead Calistoga Llc Therapies for hematologic malignancies
KR20160091440A (ko) 2008-11-13 2016-08-02 길리아드 칼리스토가 엘엘씨 혈액 종양에 대한 요법
BRPI1012333A2 (pt) 2009-03-24 2016-03-29 Gilead Calistoga Llc atropisômeros de derivados de 2-purinil-3-tolil-quinazolinonas e métodos de uso
AP2011005956A0 (en) * 2009-04-20 2011-10-31 Gilead Calistoga Llc Methods of treatment for solid tumors.
CA2768843A1 (en) 2009-07-21 2011-01-27 Gilead Calistoga Llc Treatment of liver disorders with pi3k inhibitors
BRPI1003506B1 (pt) 2010-09-24 2019-12-03 Ache Int Bvi Ltd composto alquil-piperazino-fenil-4(3h)quinazolinonas e uso do composto alquil-piperazino-fenil-4(3h)quinazolinonas associado aos receptores serotoninérgicos 5-ht1a e 5-ht2a
EP2697206B1 (en) 2011-04-10 2019-04-03 Atir Holding S.A. Heterocyclic compounds and uses thereof in the treatment of sexual disorders
NZ629684A (en) 2012-03-05 2016-10-28 Gilead Calistoga Llc Polymorphic forms of (s)-2-(1-(9h-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3h)-one
ES2595240T3 (es) 2012-07-09 2016-12-28 Lupin Limited Derivados de tetrahidroquinazolinona como inhibidores de PARP
WO2015095605A1 (en) 2013-12-20 2015-06-25 Gilead Calistoga Llc Polymorphic forms of a hydrochloride salt of (s) -2-(9h-purin-6-ylamino) propyl) -5-fluoro-3-phenylquinazolin-4 (3h) -one
NZ736970A (en) 2013-12-20 2018-11-30 Gilead Calistoga Llc Process methods for phosphatidylinositol 3-kinase inhibitors
MA40059A (fr) 2014-06-13 2015-12-17 Gilead Sciences Inc Inhibiteurs de la phosphatidylinositol 3-kinase

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1053063A (2) * 1963-05-18

Also Published As

Publication number Publication date
AT318628B (de) 1974-11-11
CH569732A5 (2) 1975-11-28
AT318615B (de) 1974-11-11
CH557829A (de) 1975-01-15
NL7107695A (2) 1971-12-07
FR2100726A1 (2) 1972-03-24
DE2027645A1 (de) 1971-12-09
FR2100726B1 (2) 1975-10-10
LU63267A1 (2) 1972-08-23
US3984555A (en) 1976-10-05
CA951319A (en) 1974-07-16
BE768137A (fr) 1971-12-06
AT317899B (de) 1974-09-25
GB1331522A (en) 1973-09-26

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