CH627182A5 - Process for the preparation of semisynthetic penicillin antibiotics - Google Patents
Process for the preparation of semisynthetic penicillin antibiotics Download PDFInfo
- Publication number
- CH627182A5 CH627182A5 CH43377A CH43377A CH627182A5 CH 627182 A5 CH627182 A5 CH 627182A5 CH 43377 A CH43377 A CH 43377A CH 43377 A CH43377 A CH 43377A CH 627182 A5 CH627182 A5 CH 627182A5
- Authority
- CH
- Switzerland
- Prior art keywords
- group
- alkyl
- acid chloride
- formula
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
- C07D499/48—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
- C07D499/58—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
- C07D499/64—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
- C07D499/68—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms with aromatic rings as additional substituents on the carbon chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/04—Preparation
- C07D499/10—Modification of an amino radical directly attached in position 6
- C07D499/12—Acylation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT47643/76A IT1053313B (it) | 1976-01-15 | 1976-01-15 | Procedimento per produrre antibiotici semisintetici |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH627182A5 true CH627182A5 (en) | 1981-12-31 |
Family
ID=11261624
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH43377A CH627182A5 (en) | 1976-01-15 | 1977-01-13 | Process for the preparation of semisynthetic penicillin antibiotics |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5287191A (da) |
| AU (1) | AU512150B2 (da) |
| BE (1) | BE850382A (da) |
| CH (1) | CH627182A5 (da) |
| DE (1) | DE2701406A1 (da) |
| DK (1) | DK13977A (da) |
| ES (1) | ES455026A1 (da) |
| FR (1) | FR2338279A1 (da) |
| GB (1) | GB1569427A (da) |
| IT (1) | IT1053313B (da) |
| NL (1) | NL7700396A (da) |
| SE (1) | SE437989B (da) |
| YU (1) | YU9277A (da) |
| ZA (1) | ZA77195B (da) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB958478A (en) * | 1962-03-13 | 1964-05-21 | Beecham Res Lab | Production of penicillins |
| FR68F (da) * | 1962-10-17 | |||
| US3351597A (en) * | 1966-11-23 | 1967-11-07 | Lilly Co Eli | Process for acylating 7-amino cephalosporanic acid |
| ZA695612B (en) * | 1968-08-23 | 1971-03-31 | Lilly Co Eli | Preparation of cephalosporin compounds |
| US3595855A (en) * | 1968-12-05 | 1971-07-27 | American Home Prod | Process for producing aminopenicillins |
| IT1043957B (it) * | 1970-12-31 | 1980-02-29 | Lorenzini Sas Inst Biochim | Processo per la preparazione della forma anidra dell acido 6, d, meno alfa aminofenilacetamido penicillanico |
| GB1494902A (en) * | 1974-05-09 | 1977-12-14 | Glaxo Lab Ltd | Penicillins |
| IT1039495B (it) * | 1975-06-26 | 1979-12-10 | Dobfar Spa | Procedimento per la preparazione di sostanze antibiotiche |
-
1976
- 1976-01-15 IT IT47643/76A patent/IT1053313B/it active
-
1977
- 1977-01-13 CH CH43377A patent/CH627182A5/de not_active IP Right Cessation
- 1977-01-14 BE BE174079A patent/BE850382A/xx not_active IP Right Cessation
- 1977-01-14 ES ES455026A patent/ES455026A1/es not_active Expired
- 1977-01-14 ZA ZA770195A patent/ZA77195B/xx unknown
- 1977-01-14 FR FR7701123A patent/FR2338279A1/fr active Granted
- 1977-01-14 NL NL7700396A patent/NL7700396A/xx not_active Application Discontinuation
- 1977-01-14 DE DE19772701406 patent/DE2701406A1/de not_active Withdrawn
- 1977-01-14 YU YU00092/77A patent/YU9277A/xx unknown
- 1977-01-14 SE SE7700393A patent/SE437989B/xx unknown
- 1977-01-14 AU AU21340/77A patent/AU512150B2/en not_active Expired
- 1977-01-14 JP JP252077A patent/JPS5287191A/ja active Pending
- 1977-01-14 GB GB1542/77A patent/GB1569427A/en not_active Expired
- 1977-01-14 DK DK13977A patent/DK13977A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DK13977A (da) | 1977-07-16 |
| JPS5287191A (en) | 1977-07-20 |
| NL7700396A (nl) | 1977-07-19 |
| ZA77195B (en) | 1977-11-30 |
| AU512150B2 (en) | 1980-09-25 |
| SE7700393L (sv) | 1977-07-16 |
| SE437989B (sv) | 1985-03-25 |
| IT1053313B (it) | 1981-08-31 |
| FR2338279B1 (da) | 1980-09-05 |
| YU9277A (en) | 1982-06-30 |
| FR2338279A1 (fr) | 1977-08-12 |
| ES455026A1 (es) | 1977-12-16 |
| GB1569427A (en) | 1980-06-18 |
| AU2134077A (en) | 1978-07-20 |
| BE850382A (fr) | 1977-07-14 |
| DE2701406A1 (de) | 1977-07-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased | ||
| PL | Patent ceased |