JPS5287191A - Process for preparing semiisynthetic penicillin antibiotics - Google Patents
Process for preparing semiisynthetic penicillin antibioticsInfo
- Publication number
- JPS5287191A JPS5287191A JP252077A JP252077A JPS5287191A JP S5287191 A JPS5287191 A JP S5287191A JP 252077 A JP252077 A JP 252077A JP 252077 A JP252077 A JP 252077A JP S5287191 A JPS5287191 A JP S5287191A
- Authority
- JP
- Japan
- Prior art keywords
- semiisynthetic
- preparing
- penicillin antibiotics
- penicillin
- antibiotics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229930182555 Penicillin Natural products 0.000 title 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 title 1
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229940049954 penicillin Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
- C07D499/48—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
- C07D499/58—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
- C07D499/64—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms
- C07D499/68—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms with aromatic rings as additional substituents on the carbon chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/04—Preparation
- C07D499/10—Modification of an amino radical directly attached in position 6
- C07D499/12—Acylation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT47643/76A IT1053313B (it) | 1976-01-15 | 1976-01-15 | Procedimento per produrre antibiotici semisintetici |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5287191A true JPS5287191A (en) | 1977-07-20 |
Family
ID=11261624
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP252077A Pending JPS5287191A (en) | 1976-01-15 | 1977-01-14 | Process for preparing semiisynthetic penicillin antibiotics |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5287191A (da) |
| AU (1) | AU512150B2 (da) |
| BE (1) | BE850382A (da) |
| CH (1) | CH627182A5 (da) |
| DE (1) | DE2701406A1 (da) |
| DK (1) | DK13977A (da) |
| ES (1) | ES455026A1 (da) |
| FR (1) | FR2338279A1 (da) |
| GB (1) | GB1569427A (da) |
| IT (1) | IT1053313B (da) |
| NL (1) | NL7700396A (da) |
| SE (1) | SE437989B (da) |
| YU (1) | YU9277A (da) |
| ZA (1) | ZA77195B (da) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS523093A (en) * | 1975-06-26 | 1977-01-11 | Dobfar Spa | Production of 66aminopencillanic acid and 77 aminodexethoxycephalospolanic acid derivative |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB958478A (en) * | 1962-03-13 | 1964-05-21 | Beecham Res Lab | Production of penicillins |
| FR68F (da) * | 1962-10-17 | |||
| US3351597A (en) * | 1966-11-23 | 1967-11-07 | Lilly Co Eli | Process for acylating 7-amino cephalosporanic acid |
| ZA695612B (en) * | 1968-08-23 | 1971-03-31 | Lilly Co Eli | Preparation of cephalosporin compounds |
| US3595855A (en) * | 1968-12-05 | 1971-07-27 | American Home Prod | Process for producing aminopenicillins |
| IT1043957B (it) * | 1970-12-31 | 1980-02-29 | Lorenzini Sas Inst Biochim | Processo per la preparazione della forma anidra dell acido 6, d, meno alfa aminofenilacetamido penicillanico |
| GB1494902A (en) * | 1974-05-09 | 1977-12-14 | Glaxo Lab Ltd | Penicillins |
-
1976
- 1976-01-15 IT IT47643/76A patent/IT1053313B/it active
-
1977
- 1977-01-13 CH CH43377A patent/CH627182A5/de not_active IP Right Cessation
- 1977-01-14 BE BE174079A patent/BE850382A/xx not_active IP Right Cessation
- 1977-01-14 ES ES455026A patent/ES455026A1/es not_active Expired
- 1977-01-14 ZA ZA770195A patent/ZA77195B/xx unknown
- 1977-01-14 FR FR7701123A patent/FR2338279A1/fr active Granted
- 1977-01-14 NL NL7700396A patent/NL7700396A/xx not_active Application Discontinuation
- 1977-01-14 DE DE19772701406 patent/DE2701406A1/de not_active Withdrawn
- 1977-01-14 YU YU00092/77A patent/YU9277A/xx unknown
- 1977-01-14 SE SE7700393A patent/SE437989B/xx unknown
- 1977-01-14 AU AU21340/77A patent/AU512150B2/en not_active Expired
- 1977-01-14 JP JP252077A patent/JPS5287191A/ja active Pending
- 1977-01-14 GB GB1542/77A patent/GB1569427A/en not_active Expired
- 1977-01-14 DK DK13977A patent/DK13977A/da not_active Application Discontinuation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS523093A (en) * | 1975-06-26 | 1977-01-11 | Dobfar Spa | Production of 66aminopencillanic acid and 77 aminodexethoxycephalospolanic acid derivative |
Also Published As
| Publication number | Publication date |
|---|---|
| DK13977A (da) | 1977-07-16 |
| NL7700396A (nl) | 1977-07-19 |
| ZA77195B (en) | 1977-11-30 |
| AU512150B2 (en) | 1980-09-25 |
| SE7700393L (sv) | 1977-07-16 |
| CH627182A5 (en) | 1981-12-31 |
| SE437989B (sv) | 1985-03-25 |
| IT1053313B (it) | 1981-08-31 |
| FR2338279B1 (da) | 1980-09-05 |
| YU9277A (en) | 1982-06-30 |
| FR2338279A1 (fr) | 1977-08-12 |
| ES455026A1 (es) | 1977-12-16 |
| GB1569427A (en) | 1980-06-18 |
| AU2134077A (en) | 1978-07-20 |
| BE850382A (fr) | 1977-07-14 |
| DE2701406A1 (de) | 1977-07-21 |
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