CH653346A5 - Analoga der neurohypophysaeren hormone oxytocin und vasopressin mit inhibierungseigenschaften gegenueber der aktivitaet dieser natuerlichen hormone. - Google Patents

Analoga der neurohypophysaeren hormone oxytocin und vasopressin mit inhibierungseigenschaften gegenueber der aktivitaet dieser natuerlichen hormone. Download PDF

Info

Publication number: CH653346A5
Authority: CH; Switzerland
Prior art keywords: hormones; oxytocin; mixture; analogs; inhibitory
Prior art date: 1982-05-10

Application number

CH2530/83A

Other languages

German (de)

English (en)

Inventor

Tomislav Dr Barth

Karel Dr Dr Sc Jost

Michal Lebl

Alena Dr Machova

Linda Dr Servitova

Jirina Dr Slaninova

Original Assignee

Ceskoslovenska Akademie Ved

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-05-10

Filing date

1983-05-09

Publication date

1985-12-31

1982-05-10 Priority claimed from CS823340A external-priority patent/CS226923B1/cs

1982-08-26 Priority claimed from CS620482A external-priority patent/CS229894B1/cs

1982-08-26 Priority claimed from CS620582A external-priority patent/CS229895B1/cs

1982-08-27 Priority claimed from CS627182A external-priority patent/CS230327B1/cs

1983-05-09 Application filed by Ceskoslovenska Akademie Ved filed Critical Ceskoslovenska Akademie Ved

1985-12-31 Publication of CH653346A5 publication Critical patent/CH653346A5/de

Links

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229960001723 oxytocin Drugs 0.000 title description 10
XNOPRXBHLZRZKH-UHFFFAOYSA-N Oxytocin Natural products N1C(=O)C(N)CSSCC(C(=O)N2C(CCC2)C(=O)NC(CC(C)C)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(C(C)CC)NC(=O)C1CC1=CC=C(O)C=C1 XNOPRXBHLZRZKH-UHFFFAOYSA-N 0.000 title description 9
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125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 8
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125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 3
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XKUKSGPZAADMRA-UHFFFAOYSA-N glycyl-glycyl-glycine Chemical compound NCC(=O)NCC(=O)NCC(O)=O XKUKSGPZAADMRA-UHFFFAOYSA-N 0.000 description 2
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VVNCNSJFMMFHPL-GSVOUGTGSA-N L-penicillamine Chemical compound CC(C)(S)[C@H](N)C(O)=O VVNCNSJFMMFHPL-GSVOUGTGSA-N 0.000 description 1
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HTLZVHNRZJPSMI-UHFFFAOYSA-N N-ethylpiperidine Chemical compound CCN1CCCCC1 HTLZVHNRZJPSMI-UHFFFAOYSA-N 0.000 description 1
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108700027018 deaminooxytocin Proteins 0.000 description 1
GTYWGUNQAMYZPF-QPLNMOKZSA-N demoxytocin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSCCC(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 GTYWGUNQAMYZPF-QPLNMOKZSA-N 0.000 description 1
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230000003054 hormonal effect Effects 0.000 description 1
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/16—Oxytocins; Vasopressins; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pyrrole Compounds (AREA)

CH2530/83A 1982-05-10 1983-05-09 Analoga der neurohypophysaeren hormone oxytocin und vasopressin mit inhibierungseigenschaften gegenueber der aktivitaet dieser natuerlichen hormone. CH653346A5 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
CS823340A CS226923B1 (cs)	1982-05-10	1982-05-10	Analogy oxytocínu s inhibičnlm účinkem a způsob jejicb výroby
CS620482A CS229894B1 (cs)	1982-08-26	1982-08-26	Analog vasopresinu a způsob jeho výroby
CS620582A CS229895B1 (cs)	1982-08-26	1982-08-26	Analog oxytocinu a způsob jeho výroby
CS627182A CS230327B1 (en)	1982-08-27	1982-08-27	Oxytocine analogue and method of preparing same

Publications (1)

Publication Number	Publication Date
CH653346A5 true CH653346A5 (de)	1985-12-31

Family

ID=27430101

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH2530/83A CH653346A5 (de)	1982-05-10	1983-05-09	Analoga der neurohypophysaeren hormone oxytocin und vasopressin mit inhibierungseigenschaften gegenueber der aktivitaet dieser natuerlichen hormone.

Country Status (9)

Country	Link
BE (1)	BE896685A (fr)
CH (1)	CH653346A5 (fr)
DE (1)	DE3317092A1 (fr)
DK (1)	DK199983A (fr)
FR (1)	FR2526318B1 (fr)
GB (1)	GB2121052B (fr)
IT (1)	IT1164212B (fr)
NL (1)	NL8301663A (fr)
SE (1)	SE460051B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT398767B (de) *	1988-05-26	1995-01-25	Gebro Broschek Gmbh	Verfahren zur reinigung eines rohpeptids mittels präparativer mitteldruckflüssigkeitschromatographie
JP2003335797A (ja) *	2000-06-28	2003-11-28	Daicel Chem Ind Ltd	ペプチド化合物及びそれを有効成分とする医薬組成物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CS216722B1 (en) *	1980-06-24	1982-11-26	Michal Lebl	Oxytocine analogues and method of making the same

1983
- 1983-05-05 GB GB08312320A patent/GB2121052B/en not_active Expired
- 1983-05-05 DK DK199983A patent/DK199983A/da not_active Application Discontinuation
- 1983-05-06 BE BE0/210719A patent/BE896685A/fr not_active IP Right Cessation
- 1983-05-09 IT IT21002/83A patent/IT1164212B/it active
- 1983-05-09 FR FR8307696A patent/FR2526318B1/fr not_active Expired
- 1983-05-09 CH CH2530/83A patent/CH653346A5/de not_active IP Right Cessation
- 1983-05-09 SE SE8302643A patent/SE460051B/sv not_active IP Right Cessation
- 1983-05-10 NL NL8301663A patent/NL8301663A/nl not_active Application Discontinuation
- 1983-05-10 DE DE19833317092 patent/DE3317092A1/de not_active Withdrawn

Also Published As

Publication number	Publication date
DK199983D0 (da)	1983-05-05
NL8301663A (nl)	1983-12-01
DE3317092A1 (de)	1983-11-10
SE460051B (sv)	1989-09-04
GB2121052B (en)	1985-08-14
GB2121052A (en)	1983-12-14
DK199983A (da)	1983-11-11
FR2526318A1 (fr)	1983-11-10
SE8302643L (sv)	1983-11-11
SE8302643D0 (sv)	1983-05-09
FR2526318B1 (fr)	1986-11-14
GB8312320D0 (en)	1983-06-08
IT1164212B (it)	1987-04-08
IT8321002A0 (it)	1983-05-09
BE896685A (fr)	1983-09-01
IT8321002A1 (it)	1984-11-09

Legal Events

Date	Code	Title	Description
1992-01-31	PL	Patent ceased
2024-10-31	PL	Patent ceased

Publication	Publication Date	Title
CA1185235A (fr)	1985-04-09	Antagonistes de l'action antidiuretique et (ou) vasoconstrictrice de l'arginine-vasopressine
EP0001295B1 (fr)	1982-03-17	Cyclopeptides analogues à la somatostatine, procédé pour leur préparation, compositions pharmaceutiques les contenant et leur application thérapeutique
CH632738A5 (de)	1982-10-29	Peptide mit gonadoliberin-wirkung und verfahren zu ihrer herstellung.
DE2256445C3 (de)	1981-11-05	Heptapeptide, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
DE2528935C2 (de)	1986-06-26	Verfahren zur Herstellung Arginylreste enthaltender Peptide und hierbei eingesetzte Zwischenprodukte
CH653345A5 (de)	1985-12-31	Analoga des vasopressins.
CH622287A5 (en)	1981-03-31	Method for the determination of thrombin or of enzymes which cleave the substrates in the same way as thrombin, and use of the method
CH633523A5 (de)	1982-12-15	Verfahren zur herstellung von peptiden und peptidderivaten.
US4483794A (en)	1984-11-20	Analogs of neurohypophysial hormones
CH649090A5 (de)	1985-04-30	Analoga von oxytocin und ihr herstellungsverfahren.
CH664968A5 (de)	1988-04-15	Gonadoliberin-derivate und verfahren zu ihrer herstellung.
EP0095557B1 (fr)	1985-12-27	Polypeptides avec activité antagoniste contre la substance P, procédé pour leur préparation, leur utilisation et procédé pour la purification de polypeptides
DE2342862C3 (de)	1981-01-15	An beiden Kettenenden Reste von a -Aminooxycarbonsäuren aufweisende Peptide mit ACTH-Wirkung, Verfahren zu ihrer Herstellung und diese Peptide enthaltende Arzneimittel
CH422813A (de)	1966-10-31	Verfahren zur Herstellung neuer Polypeptide
EP0258784B1 (fr)	1992-12-09	Composés chromogènes, leur procédé de préparation et leur emploi
DE2341775C3 (de)	1980-12-18	In N-terminaler Stellung den Rest einer Aminooxysäure aufweisende Peptide mit ACTH-Wirkung, Verfahren zu ihrer Herstellung sowie diese Peptide enthaltende Arzneimittel
CH658061A5 (de)	1986-10-15	Analoga von neurohypophysaeren hormonen mit inhibierungswirkungen.
DE3317092A1 (de)	1983-11-10	Analoga von neurohypophysaeren hormonen mit inhibierungseigenschaften, ihre herstellung und pharmazeutische mittel
EP0003122B1 (fr)	1981-04-29	Procédé de préparation de peptides contenant des restes cystéiniques
EP0001075B1 (fr)	1980-11-26	Chaîne A de l'insuline humaine, partiellement protégée, et procédé pour son obtention
Mezö et al.	1993	New Gaba-containing analogues of human growth hormone-releasing hormone (1–30)-amide: I. Synthesis and in vitro biological activity
DE2347456A1 (de)	1974-04-11	Polypeptide und verfahren zu deren herstellung
Zaoral et al.	1979	[1-β-Mercaptopropionic acid, 8-norarginine] vasopressin and [1-β-mercaptopropionic acid, 8-D-norarginine] vasopressin. Two analogs with strong biological effects
AT249282B (de)	1966-09-12	Verfahren zur Herstellung neuer Heneikosapeptide
CH608788A5 (en)	1979-01-31	Process for the preparation of novel peptides having a high adrenocorticotropic action