CH653890A5 - Composizioni farmaceutiche ad attivita antineoplastica. - Google Patents

Composizioni farmaceutiche ad attivita antineoplastica. Download PDF

Info

Publication number: CH653890A5
Authority: CH; Switzerland
Prior art keywords: pharmaceutical compositions; compositions according; formula; cholesterol; parts
Prior art date: 1982-05-28

Application number

CH2772/83A

Other languages

English (en)

Italian (it)

Inventor

Emanuel Revici

Original Assignee

Fcn Srl

Alphatime Limited Company Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-05-28

Filing date

1983-05-20

Publication date

1986-01-31

1983-05-20 Application filed by Fcn Srl, Alphatime Limited Company Inc filed Critical Fcn Srl

1986-01-31 Publication of CH653890A5 publication Critical patent/CH653890A5/it

Links

239000008194 pharmaceutical composition Substances 0.000 title claims description 15
230000000118 anti-neoplastic effect Effects 0.000 title claims description 4
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims description 22
235000012000 cholesterol Nutrition 0.000 claims description 11
KUGBQWBWWNPMIT-UHFFFAOYSA-N 1,1,2,2,3,3,4,4-octafluoropentan-1-ol Chemical compound CC(F)(F)C(F)(F)C(F)(F)C(O)(F)F KUGBQWBWWNPMIT-UHFFFAOYSA-N 0.000 claims description 8
GUAMVMSOIYAUSK-UHFFFAOYSA-N 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-hexadecafluorononan-1-ol Chemical compound CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(O)(F)F GUAMVMSOIYAUSK-UHFFFAOYSA-N 0.000 claims description 7
239000008159 sesame oil Substances 0.000 claims description 6
235000011803 sesame oil Nutrition 0.000 claims description 6
125000001028 difluoromethyl group Chemical group [H]C(F)(F)* 0.000 claims description 2
150000001298 alcohols Chemical class 0.000 claims 2
239000002904 solvent Substances 0.000 claims 2
239000000203 mixture Substances 0.000 description 12
241001465754 Metazoa Species 0.000 description 8
241000699670 Mus sp. Species 0.000 description 4
206010028980 Neoplasm Diseases 0.000 description 4
230000001925 catabolic effect Effects 0.000 description 4
241000700159 Rattus Species 0.000 description 3
238000005303 weighing Methods 0.000 description 3
231100000403 acute toxicity Toxicity 0.000 description 2
230000007665 chronic toxicity Effects 0.000 description 2
231100000160 chronic toxicity Toxicity 0.000 description 2
239000000470 constituent Substances 0.000 description 2
230000002349 favourable effect Effects 0.000 description 2
230000009543 pathological alteration Effects 0.000 description 2
238000003756 stirring Methods 0.000 description 2
231100000456 subacute toxicity Toxicity 0.000 description 2
238000010254 subcutaneous injection Methods 0.000 description 2
239000007929 subcutaneous injection Substances 0.000 description 2
208000024891 symptom Diseases 0.000 description 2
BYKNGMLDSIEFFG-UHFFFAOYSA-N 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptan-1-ol Chemical compound OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F BYKNGMLDSIEFFG-UHFFFAOYSA-N 0.000 description 1
206010052428 Wound Diseases 0.000 description 1
208000027418 Wounds and injury Diseases 0.000 description 1
230000002159 abnormal effect Effects 0.000 description 1
230000005856 abnormality Effects 0.000 description 1
238000009825 accumulation Methods 0.000 description 1
239000004480 active ingredient Substances 0.000 description 1
230000001154 acute effect Effects 0.000 description 1
230000007059 acute toxicity Effects 0.000 description 1
230000001195 anabolic effect Effects 0.000 description 1
230000009286 beneficial effect Effects 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
230000034994 death Effects 0.000 description 1
238000004090 dissolution Methods 0.000 description 1
230000001747 exhibiting effect Effects 0.000 description 1
239000012530 fluid Substances 0.000 description 1
230000035876 healing Effects 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
238000010255 intramuscular injection Methods 0.000 description 1
239000007927 intramuscular injection Substances 0.000 description 1
230000003902 lesion Effects 0.000 description 1
238000000034 method Methods 0.000 description 1
230000017074 necrotic cell death Effects 0.000 description 1
231100000252 nontoxic Toxicity 0.000 description 1
230000003000 nontoxic effect Effects 0.000 description 1
239000000243 solution Substances 0.000 description 1
238000007920 subcutaneous administration Methods 0.000 description 1
231100000331 toxic Toxicity 0.000 description 1
230000002588 toxic effect Effects 0.000 description 1
231100000419 toxicity Toxicity 0.000 description 1
230000001988 toxicity Effects 0.000 description 1
239000003981 vehicle Substances 0.000 description 1
238000012795 verification Methods 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C31/34—Halogenated alcohols
- C07C31/38—Halogenated alcohols containing only fluorine as halogen

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

CH2772/83A 1982-05-28 1983-05-20 Composizioni farmaceutiche ad attivita antineoplastica. CH653890A5 (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT8221553A IT8221553A0 (it)	1982-05-28	1982-05-28	Composizioni farmaceutiche adattivita' antineoplastica.

Publications (1)

Publication Number	Publication Date
CH653890A5 true CH653890A5 (it)	1986-01-31

Family

ID=11183507

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH2772/83A CH653890A5 (it)	1982-05-28	1983-05-20	Composizioni farmaceutiche ad attivita antineoplastica.

Country Status (16)

Country	Link
JP (1)	JPS591414A (fr)
AU (2)	AU552557B2 (fr)
BE (1)	BE896838A (fr)
CH (1)	CH653890A5 (fr)
DE (1)	DE3319304A1 (fr)
FR (1)	FR2527439A1 (fr)
GB (1)	GB2121280B (fr)
IE (1)	IE55137B1 (fr)
IL (1)	IL68796A0 (fr)
IN (1)	IN157042B (fr)
IT (1)	IT8221553A0 (fr)
LU (1)	LU84827A1 (fr)
NL (1)	NL8301899A (fr)
NZ (1)	NZ204393A (fr)
SE (1)	SE8302976L (fr)
ZA (1)	ZA833871B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3836971C1 (fr) *	1988-10-31	1990-05-17	Weck, Wolfgang, Dr.Med., 6990 Bad Mergentheim, De

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3219004C1 (de) *	1982-05-19	1984-03-01	Philippine Dr. 8000 München Hartmann	Arzneimittel zur Behandlung von Tumoren

1982
- 1982-05-28 IT IT8221553A patent/IT8221553A0/it unknown
1983
- 1983-05-20 CH CH2772/83A patent/CH653890A5/it not_active IP Right Cessation
- 1983-05-26 GB GB08314540A patent/GB2121280B/en not_active Expired
- 1983-05-26 JP JP58093889A patent/JPS591414A/ja active Pending
- 1983-05-26 AU AU15000/83A patent/AU552557B2/en not_active Expired - Fee Related
- 1983-05-26 BE BE2/60100A patent/BE896838A/nl not_active IP Right Cessation
- 1983-05-26 IL IL68796A patent/IL68796A0/xx unknown
- 1983-05-26 SE SE8302976A patent/SE8302976L/ not_active Application Discontinuation
- 1983-05-27 IN IN673/CAL/83A patent/IN157042B/en unknown
- 1983-05-27 IE IE1259/83A patent/IE55137B1/en unknown
- 1983-05-27 LU LU84827A patent/LU84827A1/fr unknown
- 1983-05-27 ZA ZA833871A patent/ZA833871B/xx unknown
- 1983-05-27 DE DE19833319304 patent/DE3319304A1/de not_active Ceased
- 1983-05-27 FR FR8308776A patent/FR2527439A1/fr not_active Withdrawn
- 1983-05-27 NL NL8301899A patent/NL8301899A/nl not_active Application Discontinuation
- 1983-05-27 NZ NZ204393A patent/NZ204393A/en unknown
1988
- 1988-05-04 AU AU15570/88A patent/AU1557088A/en not_active Abandoned

Also Published As

Publication number	Publication date
AU1557088A (en)	1988-11-10
NL8301899A (nl)	1983-12-16
ZA833871B (en)	1984-07-25
IN157042B (fr)	1986-01-04
IE55137B1 (en)	1990-06-06
LU84827A1 (fr)	1983-11-17
BE896838A (nl)	1983-09-16
GB8314540D0 (en)	1983-06-29
FR2527439A1 (fr)	1983-12-02
GB2121280B (en)	1985-08-29
SE8302976D0 (sv)	1983-05-26
SE8302976L (sv)	1983-11-29
GB2121280A (en)	1983-12-21
IE831259L (en)	1983-11-28
AU552557B2 (en)	1986-06-05
IT8221553A0 (it)	1982-05-28
JPS591414A (ja)	1984-01-06
IL68796A0 (en)	1983-09-30
DE3319304A1 (de)	1983-12-01
NZ204393A (en)	1986-03-14
AU1500083A (en)	1983-12-01

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Legal Events

Date	Code	Title	Description
1988-01-29	PL	Patent ceased
2024-10-31	PL	Patent ceased