JPS591414A - 少なくとも１種のポリフルオロ化されたアルコ−ルを含有する医薬 - Google Patents

少なくとも１種のポリフルオロ化されたアルコ−ルを含有する医薬

Info

Publication number: JPS591414A
Authority: JP; Japan
Prior art keywords: formula; medicament; medicament according; component; parts
Prior art date: 1982-05-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP58093889A

Other languages

English (en)

Japanese (ja)

Inventor

エマヌエル・レビチ

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

ARUFUATAIMU Ltd CO Inc

ETSUFUE CHI ENNE ETSUSE ERURE ERURE

FCN Srl

Original Assignee

ARUFUATAIMU Ltd CO Inc

ETSUFUE CHI ENNE ETSUSE ERURE ERURE

FCN Srl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-05-28

Filing date

1983-05-26

Publication date

1984-01-06

1983-05-26 Application filed by ARUFUATAIMU Ltd CO Inc, ETSUFUE CHI ENNE ETSUSE ERURE ERURE, FCN Srl filed Critical ARUFUATAIMU Ltd CO Inc

1984-01-06 Publication of JPS591414A publication Critical patent/JPS591414A/ja

Status Pending legal-status Critical Current

Links

239000003814 drug Substances 0.000 title claims description 31
150000001298 alcohols Chemical class 0.000 title claims description 5
229940079593 drug Drugs 0.000 title description 6
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims description 18
235000012000 cholesterol Nutrition 0.000 claims description 9
239000008159 sesame oil Substances 0.000 claims description 6
235000011803 sesame oil Nutrition 0.000 claims description 6
KUGBQWBWWNPMIT-UHFFFAOYSA-N 1,1,2,2,3,3,4,4-octafluoropentan-1-ol Chemical compound CC(F)(F)C(F)(F)C(F)(F)C(O)(F)F KUGBQWBWWNPMIT-UHFFFAOYSA-N 0.000 claims description 5
239000004480 active ingredient Substances 0.000 claims description 3
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 2
239000004615 ingredient Substances 0.000 claims description 2
239000002552 dosage form Substances 0.000 claims 2
239000002904 solvent Substances 0.000 claims 2
230000000259 anti-tumor effect Effects 0.000 claims 1
238000007911 parenteral administration Methods 0.000 claims 1
241001465754 Metazoa Species 0.000 description 7
GUAMVMSOIYAUSK-UHFFFAOYSA-N 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-hexadecafluorononan-1-ol Chemical compound CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(O)(F)F GUAMVMSOIYAUSK-UHFFFAOYSA-N 0.000 description 6
150000001875 compounds Chemical class 0.000 description 6
206010028980 Neoplasm Diseases 0.000 description 5
241000699670 Mus sp. Species 0.000 description 4
230000001925 catabolic effect Effects 0.000 description 4
238000005303 weighing Methods 0.000 description 4
241000700159 Rattus Species 0.000 description 3
230000007059 acute toxicity Effects 0.000 description 3
231100000403 acute toxicity Toxicity 0.000 description 3
230000001195 anabolic effect Effects 0.000 description 3
241000283086 Equidae Species 0.000 description 2
AMQJEAYHLZJPGS-UHFFFAOYSA-N N-Pentanol Chemical compound CCCCCO AMQJEAYHLZJPGS-UHFFFAOYSA-N 0.000 description 2
230000007665 chronic toxicity Effects 0.000 description 2
231100000160 chronic toxicity Toxicity 0.000 description 2
230000000694 effects Effects 0.000 description 2
230000002349 favourable effect Effects 0.000 description 2
231100000915 pathological change Toxicity 0.000 description 2
230000036285 pathological change Effects 0.000 description 2
238000003756 stirring Methods 0.000 description 2
208000024891 symptom Diseases 0.000 description 2
231100000419 toxicity Toxicity 0.000 description 2
230000001988 toxicity Effects 0.000 description 2
241000699666 Mus <mouse, genus> Species 0.000 description 1
206010070863 Toxicity to various agents Diseases 0.000 description 1
206010052428 Wound Diseases 0.000 description 1
208000027418 Wounds and injury Diseases 0.000 description 1
230000002159 abnormal effect Effects 0.000 description 1
239000000654 additive Substances 0.000 description 1
230000000996 additive effect Effects 0.000 description 1
230000009286 beneficial effect Effects 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
230000034994 death Effects 0.000 description 1
230000001934 delay Effects 0.000 description 1
230000037213 diet Effects 0.000 description 1
235000005911 diet Nutrition 0.000 description 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
230000009977 dual effect Effects 0.000 description 1
238000002474 experimental method Methods 0.000 description 1
235000013305 food Nutrition 0.000 description 1
230000002496 gastric effect Effects 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
238000010255 intramuscular injection Methods 0.000 description 1
239000007927 intramuscular injection Substances 0.000 description 1
230000017074 necrotic cell death Effects 0.000 description 1
231100000956 nontoxicity Toxicity 0.000 description 1
230000000144 pharmacologic effect Effects 0.000 description 1
230000035479 physiological effects, processes and functions Effects 0.000 description 1
239000000243 solution Substances 0.000 description 1
231100000456 subacute toxicity Toxicity 0.000 description 1
238000007920 subcutaneous administration Methods 0.000 description 1
238000010254 subcutaneous injection Methods 0.000 description 1
239000007929 subcutaneous injection Substances 0.000 description 1
239000000126 substance Substances 0.000 description 1
238000010792 warming Methods 0.000 description 1
230000037303 wrinkles Effects 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C31/34—Halogenated alcohols
- C07C31/38—Halogenated alcohols containing only fluorine as halogen

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

JP58093889A 1982-05-28 1983-05-26 少なくとも１種のポリフルオロ化されたアルコ−ルを含有する医薬 Pending JPS591414A (ja)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT21553A/82		1982-05-28
IT8221553A IT8221553A0 (it)	1982-05-28	1982-05-28	Composizioni farmaceutiche adattivita' antineoplastica.

Publications (1)

Publication Number	Publication Date
JPS591414A true JPS591414A (ja)	1984-01-06

Family

ID=11183507

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP58093889A Pending JPS591414A (ja)	1982-05-28	1983-05-26	少なくとも１種のポリフルオロ化されたアルコ−ルを含有する医薬

Country Status (16)

Country	Link
JP (1)	JPS591414A (fr)
AU (2)	AU552557B2 (fr)
BE (1)	BE896838A (fr)
CH (1)	CH653890A5 (fr)
DE (1)	DE3319304A1 (fr)
FR (1)	FR2527439A1 (fr)
GB (1)	GB2121280B (fr)
IE (1)	IE55137B1 (fr)
IL (1)	IL68796A0 (fr)
IN (1)	IN157042B (fr)
IT (1)	IT8221553A0 (fr)
LU (1)	LU84827A1 (fr)
NL (1)	NL8301899A (fr)
NZ (1)	NZ204393A (fr)
SE (1)	SE8302976L (fr)
ZA (1)	ZA833871B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3836971C1 (fr) *	1988-10-31	1990-05-17	Weck, Wolfgang, Dr.Med., 6990 Bad Mergentheim, De

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3219004C1 (de) *	1982-05-19	1984-03-01	Philippine Dr. 8000 München Hartmann	Arzneimittel zur Behandlung von Tumoren

1982
- 1982-05-28 IT IT8221553A patent/IT8221553A0/it unknown
1983
- 1983-05-20 CH CH2772/83A patent/CH653890A5/it not_active IP Right Cessation
- 1983-05-26 GB GB08314540A patent/GB2121280B/en not_active Expired
- 1983-05-26 JP JP58093889A patent/JPS591414A/ja active Pending
- 1983-05-26 AU AU15000/83A patent/AU552557B2/en not_active Expired - Fee Related
- 1983-05-26 BE BE2/60100A patent/BE896838A/nl not_active IP Right Cessation
- 1983-05-26 IL IL68796A patent/IL68796A0/xx unknown
- 1983-05-26 SE SE8302976A patent/SE8302976L/ not_active Application Discontinuation
- 1983-05-27 IN IN673/CAL/83A patent/IN157042B/en unknown
- 1983-05-27 IE IE1259/83A patent/IE55137B1/en unknown
- 1983-05-27 LU LU84827A patent/LU84827A1/fr unknown
- 1983-05-27 ZA ZA833871A patent/ZA833871B/xx unknown
- 1983-05-27 DE DE19833319304 patent/DE3319304A1/de not_active Ceased
- 1983-05-27 FR FR8308776A patent/FR2527439A1/fr not_active Withdrawn
- 1983-05-27 NL NL8301899A patent/NL8301899A/nl not_active Application Discontinuation
- 1983-05-27 NZ NZ204393A patent/NZ204393A/en unknown
1988
- 1988-05-04 AU AU15570/88A patent/AU1557088A/en not_active Abandoned

Also Published As

Publication number	Publication date
AU1557088A (en)	1988-11-10
NL8301899A (nl)	1983-12-16
ZA833871B (en)	1984-07-25
IN157042B (fr)	1986-01-04
IE55137B1 (en)	1990-06-06
LU84827A1 (fr)	1983-11-17
BE896838A (nl)	1983-09-16
GB8314540D0 (en)	1983-06-29
FR2527439A1 (fr)	1983-12-02
GB2121280B (en)	1985-08-29
SE8302976D0 (sv)	1983-05-26
SE8302976L (sv)	1983-11-29
GB2121280A (en)	1983-12-21
IE831259L (en)	1983-11-28
AU552557B2 (en)	1986-06-05
IT8221553A0 (it)	1982-05-28
IL68796A0 (en)	1983-09-30
DE3319304A1 (de)	1983-12-01
CH653890A5 (it)	1986-01-31
NZ204393A (en)	1986-03-14
AU1500083A (en)	1983-12-01

Publication	Publication Date	Title
TW386877B (en)	2000-04-11	Antitumour compositions containing taxane derivatives
JPH05505615A (ja)	1993-08-19	医薬組成物
Barrowman et al.	1975	Diarrhoeae in thyroid medullary carcinoma: role of prostaglandins and therapeutic effect of nutmeg.
CN101590057A (zh)	2009-12-02	含有紫杉烷衍生物的抗肿瘤组合物
CA2286557A1 (fr)	1998-10-22	Phorbol esters utilises en tant qu'agents anti-neoplasiques
Ariel	1970	Therapeutic effects of hydroxyurea. Experience with 118 patients with inoperable solid tumors
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Almersjö et al.	1975	Concentration of biologically active 5-fluorouracil in general circulation during continuous portal infusion in man: a preliminary report
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Kondo et al.	1961	Production of metastases by treatment with carcinostatic agents I. Effects of carcinostatic agents on the host
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Cyriax	1961	Epidural local anaesthesia
EP3127544B1 (fr)	2021-09-15	Médicament antitumoral contenant un complexe de platine antitumoral et promoteur de l'effet antitumoral
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Bliss et al.	1940	Effect of Sulfapyridine, Sulfathiazole and Sulfamethylthiazole upon Severe Staphylococcal Infection in Mice.
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Killen et al.	1982	Phase II studies of methyl glyoxal bis‐guanylhydrazone (NSC 32946) in carcinoma of the colon and lung
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