CH656308A5 - Compositions pharmaceutiques contenant du salbutamol. - Google Patents

Compositions pharmaceutiques contenant du salbutamol. Download PDF

Info

Publication number: CH656308A5
Authority: CH; Switzerland
Prior art keywords: pharmaceutical composition; cellulose; composition according; salbutamol; liquid
Prior art date: 1982-05-27

Application number

CH2779/83A

Other languages

English (en)

French (fr)

Inventor

John Malcolm Padfield

Cheryl Vanessa Groom

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-05-27

Filing date

1983-05-20

Publication date

1986-06-30

1983-05-20 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1986-06-30 Publication of CH656308A5 publication Critical patent/CH656308A5/fr

Links

239000008194 pharmaceutical composition Substances 0.000 title claims description 23
NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 title claims description 19
229960002052 salbutamol Drugs 0.000 title claims description 16
229920002678 cellulose Polymers 0.000 claims description 19
239000001913 cellulose Substances 0.000 claims description 19
150000003839 salts Chemical class 0.000 claims description 11
239000007788 liquid Substances 0.000 claims description 9
239000001866 hydroxypropyl methyl cellulose Chemical class 0.000 claims description 7
229920003088 hydroxypropyl methyl cellulose Chemical class 0.000 claims description 7
235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 7
UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical class OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims description 7
238000002360 preparation method Methods 0.000 claims description 7
229920000663 Hydroxyethyl cellulose Chemical class 0.000 claims description 5
239000004354 Hydroxyethyl cellulose Chemical class 0.000 claims description 5
235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 5
229920002134 Carboxymethyl cellulose Chemical class 0.000 claims description 3
239000001768 carboxy methyl cellulose Chemical class 0.000 claims description 3
235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 3
239000008112 carboxymethyl-cellulose Chemical class 0.000 claims description 3
239000006185 dispersion Substances 0.000 claims description 3
239000001856 Ethyl cellulose Substances 0.000 claims description 2
ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical class CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims description 2
229920001479 Hydroxyethyl methyl cellulose Chemical class 0.000 claims description 2
229920002153 Hydroxypropyl cellulose Chemical class 0.000 claims description 2
125000000217 alkyl group Chemical group 0.000 claims description 2
229920001249 ethyl cellulose Polymers 0.000 claims description 2
235000019325 ethyl cellulose Nutrition 0.000 claims description 2
239000001761 ethyl methyl cellulose Chemical class 0.000 claims description 2
235000010944 ethyl methyl cellulose Nutrition 0.000 claims description 2
229920013819 hydroxyethyl ethylcellulose Chemical class 0.000 claims description 2
229920003063 hydroxymethyl cellulose Chemical class 0.000 claims description 2
229940031574 hydroxymethyl cellulose Drugs 0.000 claims description 2
239000001863 hydroxypropyl cellulose Chemical class 0.000 claims description 2
235000010977 hydroxypropyl cellulose Nutrition 0.000 claims description 2
229920000609 methyl cellulose Chemical class 0.000 claims description 2
239000001923 methylcellulose Chemical class 0.000 claims description 2
235000010981 methylcellulose Nutrition 0.000 claims description 2
RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 1
239000012458 free base Substances 0.000 claims 1
-1 hydroxyalkyl ether Chemical compound 0.000 claims 1
239000000203 mixture Substances 0.000 description 13
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 13
BNPSSFBOAGDEEL-UHFFFAOYSA-N albuterol sulfate Chemical compound OS(O)(=O)=O.CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1.CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 BNPSSFBOAGDEEL-UHFFFAOYSA-N 0.000 description 6
238000009472 formulation Methods 0.000 description 6
YASYEJJMZJALEJ-UHFFFAOYSA-N Citric acid monohydrate Chemical compound O.OC(=O)CC(O)(C(O)=O)CC(O)=O YASYEJJMZJALEJ-UHFFFAOYSA-N 0.000 description 3
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
229960002303 citric acid monohydrate Drugs 0.000 description 3
238000001246 colloidal dispersion Methods 0.000 description 3
239000012153 distilled water Substances 0.000 description 3
239000000243 solution Substances 0.000 description 3
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 2
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
229930006000 Sucrose Natural products 0.000 description 2
239000002253 acid Substances 0.000 description 2
WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
239000000796 flavoring agent Substances 0.000 description 2
235000013355 food flavoring agent Nutrition 0.000 description 2
235000003599 food sweetener Nutrition 0.000 description 2
NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 2
239000001509 sodium citrate Substances 0.000 description 2
229960000999 sodium citrate dihydrate Drugs 0.000 description 2
239000000600 sorbitol Substances 0.000 description 2
239000005720 sucrose Substances 0.000 description 2
239000003765 sweetening agent Substances 0.000 description 2
239000002562 thickening agent Substances 0.000 description 2
HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 2
FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 description 1
LNAZSHAWQACDHT-XIYTZBAFSA-N (2r,3r,4s,5r,6s)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2s,3r,4s,5r,6r)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6r)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical compound CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 description 1
239000005711 Benzoic acid Substances 0.000 description 1
QFOHBWFCKVYLES-UHFFFAOYSA-N Butylparaben Chemical compound CCCCOC(=O)C1=CC=C(O)C=C1 QFOHBWFCKVYLES-UHFFFAOYSA-N 0.000 description 1
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
UDIPTWFVPPPURJ-UHFFFAOYSA-M Cyclamate Chemical compound [Na+].[O-]S(=O)(=O)NC1CCCCC1 UDIPTWFVPPPURJ-UHFFFAOYSA-M 0.000 description 1
WINXNKPZLFISPD-UHFFFAOYSA-M Saccharin sodium Chemical compound [Na+].C1=CC=C2C(=O)[N-]S(=O)(=O)C2=C1 WINXNKPZLFISPD-UHFFFAOYSA-M 0.000 description 1
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
239000004480 active ingredient Substances 0.000 description 1
229920013820 alkyl cellulose Polymers 0.000 description 1
150000005215 alkyl ethers Chemical class 0.000 description 1
230000000845 anti-microbial effect Effects 0.000 description 1
239000004599 antimicrobial Substances 0.000 description 1
239000013011 aqueous formulation Substances 0.000 description 1
239000007864 aqueous solution Substances 0.000 description 1
235000010233 benzoic acid Nutrition 0.000 description 1
239000000872 buffer Substances 0.000 description 1
239000000337 buffer salt Substances 0.000 description 1
239000011575 calcium Substances 0.000 description 1
229910052791 calcium Inorganic materials 0.000 description 1
229960004106 citric acid Drugs 0.000 description 1
239000003086 colorant Substances 0.000 description 1
239000000470 constituent Substances 0.000 description 1
239000000625 cyclamic acid and its Na and Ca salt Substances 0.000 description 1
230000006866 deterioration Effects 0.000 description 1
150000002170 ethers Chemical class 0.000 description 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
229920013821 hydroxy alkyl cellulose Polymers 0.000 description 1
125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
238000011065 in-situ storage Methods 0.000 description 1
238000001990 intravenous administration Methods 0.000 description 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
230000002335 preservative effect Effects 0.000 description 1
125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
239000008213 purified water Substances 0.000 description 1
229940085605 saccharin sodium Drugs 0.000 description 1
WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
235000010234 sodium benzoate Nutrition 0.000 description 1
239000004299 sodium benzoate Substances 0.000 description 1
229960001462 sodium cyclamate Drugs 0.000 description 1
159000000000 sodium salts Chemical class 0.000 description 1
239000007787 solid Substances 0.000 description 1
239000000126 substance Substances 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Inorganic Chemistry (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

CH2779/83A 1982-05-27 1983-05-20 Compositions pharmaceutiques contenant du salbutamol. CH656308A5 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB8215502		1982-05-27

Publications (1)

Publication Number	Publication Date
CH656308A5 true CH656308A5 (fr)	1986-06-30

Family

ID=10530673

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH2779/83A CH656308A5 (fr)	1982-05-27	1983-05-20	Compositions pharmaceutiques contenant du salbutamol.

Country Status (25)

Country	Link
JP (1)	JPH0629181B2 (ja)
AT (1)	AT390191B (ja)
AU (1)	AU567675B2 (ja)
BE (1)	BE896870A (ja)
CA (1)	CA1203176A (ja)
CH (1)	CH656308A5 (ja)
DE (1)	DE3319356C2 (ja)
DK (1)	DK167558B1 (ja)
ES (1)	ES8502336A1 (ja)
FI (1)	FI81257C (ja)
FR (1)	FR2527442B1 (ja)
GR (1)	GR82681B (ja)
IE (1)	IE55139B1 (ja)
IL (1)	IL68805A0 (ja)
IT (1)	IT1174759B (ja)
LU (1)	LU84828A1 (ja)
MY (1)	MY8700275A (ja)
NL (1)	NL192663C (ja)
NO (1)	NO163166C (ja)
NZ (1)	NZ204385A (ja)
PH (1)	PH19601A (ja)
PT (1)	PT76773B (ja)
SE (1)	SE454946B (ja)
ZA (1)	ZA833854B (ja)
ZW (1)	ZW11883A1 (ja)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3624213A (en) *	1963-10-30	1971-11-30	Merck & Co Inc	Method of sterilizing aqueous pharmaceutical solutions employing propylene oxide and entrained air
GB1200886A (en) *	1966-09-23	1970-08-05	Allen & Hanburys Ltd	Phenylaminoethanol derivatives
GB1453034A (en) *	1972-12-15	1976-10-20	Boehringer Sohn Ingelheim	Pharmaceutical composition for treating spasticity
JPS5831210B2 (ja) *	1973-04-09	1983-07-05	武田薬品工業株式会社	アンテイナスイセイケンダクエキノセイゾウホウ
DE2714065A1 (de) *	1977-03-30	1978-10-12	Boehringer Mannheim Gmbh	Instillationszubereitung

1983
- 1983-05-20 CH CH2779/83A patent/CH656308A5/fr not_active IP Right Cessation
- 1983-05-24 GR GR71454A patent/GR82681B/el unknown
- 1983-05-26 NO NO831875A patent/NO163166C/no not_active IP Right Cessation
- 1983-05-26 FR FR8308722A patent/FR2527442B1/fr not_active Expired
- 1983-05-27 PH PH28974A patent/PH19601A/en unknown
- 1983-05-27 DE DE3319356A patent/DE3319356C2/de not_active Expired - Lifetime
- 1983-05-27 NL NL8301900A patent/NL192663C/nl not_active IP Right Cessation
- 1983-05-27 FI FI831893A patent/FI81257C/fi not_active IP Right Cessation
- 1983-05-27 IE IE1267/83A patent/IE55139B1/en not_active IP Right Cessation
- 1983-05-27 ZW ZW118/83A patent/ZW11883A1/xx unknown
- 1983-05-27 BE BE0/210866A patent/BE896870A/fr not_active IP Right Cessation
- 1983-05-27 AU AU15039/83A patent/AU567675B2/en not_active Expired
- 1983-05-27 SE SE8303012A patent/SE454946B/sv not_active IP Right Cessation
- 1983-05-27 AT AT0195283A patent/AT390191B/de not_active IP Right Cessation
- 1983-05-27 NZ NZ204385A patent/NZ204385A/en unknown
- 1983-05-27 IL IL68805A patent/IL68805A0/xx not_active IP Right Cessation
- 1983-05-27 JP JP58093896A patent/JPH0629181B2/ja not_active Expired - Lifetime
- 1983-05-27 LU LU84828A patent/LU84828A1/fr unknown
- 1983-05-27 IT IT48384/83A patent/IT1174759B/it active Protection Beyond IP Right Term
- 1983-05-27 CA CA000429095A patent/CA1203176A/en not_active Expired
- 1983-05-27 PT PT76773A patent/PT76773B/pt unknown
- 1983-05-27 DK DK241783A patent/DK167558B1/da not_active IP Right Cessation
- 1983-05-27 ZA ZA833854A patent/ZA833854B/xx unknown
- 1983-05-27 ES ES522752A patent/ES8502336A1/es not_active Expired
1987
- 1987-12-30 MY MY275/87A patent/MY8700275A/xx unknown

Also Published As

Publication number	Publication date
CA1203176A (en)	1986-04-15
FI81257C (fi)	1990-10-10
NZ204385A (en)	1986-07-11
DK241783A (da)	1983-11-28
DK241783D0 (da)	1983-05-27
AT390191B (de)	1990-03-26
NL192663C (nl)	1997-12-02
LU84828A1 (fr)	1985-03-21
FI831893A0 (fi)	1983-05-27
SE8303012D0 (sv)	1983-05-27
DK167558B1 (da)	1993-11-22
IL68805A0 (en)	1983-09-30
PT76773A (en)	1983-06-01
AU567675B2 (en)	1987-12-03
MY8700275A (en)	1987-12-31
IT1174759B (it)	1987-07-01
ES522752A0 (es)	1985-01-01
SE8303012L (sv)	1983-11-28
ZW11883A1 (en)	1984-12-19
PH19601A (en)	1986-05-27
ATA195283A (de)	1989-09-15
AU1503983A (en)	1983-12-01
PT76773B (en)	1986-03-27
SE454946B (sv)	1988-06-13
DE3319356C2 (de)	1996-07-04
NL8301900A (nl)	1983-12-16
NL192663B (ja)	1997-08-01
DE3319356A1 (de)	1983-12-01
BE896870A (fr)	1983-11-28
IE55139B1 (en)	1990-06-06
NO163166B (no)	1990-01-08
NO831875L (no)	1983-11-28
IE831267L (en)	1983-11-27
FR2527442B1 (fr)	1987-07-17
ES8502336A1 (es)	1985-01-01
JPH0629181B2 (ja)	1994-04-20
JPS591411A (ja)	1984-01-06
ZA833854B (en)	1985-01-30
NO163166C (no)	1990-05-02
IT8348384A0 (it)	1983-05-27
FR2527442A1 (fr)	1983-12-02
FI831893L (fi)	1983-11-28
GR82681B (ja)	1985-02-07
FI81257B (fi)	1990-06-29

Legal Events

Date	Code	Title	Description
2003-06-13	PL	Patent ceased

Publication	Publication Date	Title
FR2464714A1 (fr)	1981-03-20	Composition pharmaceutique topique contenant de la triethylenetetramine
FR2560523A1 (fr)	1985-09-06	Solution ophtalmique contenant du pranoprofene et de l'acide borique
KR20050057251A (ko)	2005-06-16	라타노프로스트를 유효 성분으로 하는 투명한 점안액
BE1000624A5 (fr)	1989-02-21	Composition pharmaceutique contenant de la ranitidine.
BG63031B1 (bg)	2001-02-28	Противовъзпалителни състави,съдържащи пироксикам,за локално приложение
CA1242458A (fr)	1988-09-27	Ethers-oxydes et ethers-oximes d'alcoylaminoalcools comme medicaments, produits nouveaux et procedes pour leur preparation
JPH0327532B2 (ja)	1991-04-16
FR2609394A1 (fr)	1988-07-15	Solution aqueuse contenant un acide quinolone carboxylique
US4594359A (en)	1986-06-10	Pharmaceutical compositions
WO1996014840A1 (en)	1996-05-23	Use of menthyl lactate as a pain reliever
EP0445540B1 (en)	1995-04-19	Antimycotic external imidazole preparations
GB2120942A (en)	1983-12-14	Salbutamol compositions
HUT63060A (en)	1993-07-28	Process for producing pharmaceutical compositions locally applicable on nose and eye, comprising bradykinin antagonists
US5061486A (en)	1991-10-29	Dithranol composition containing no oily ingredients
FR2527442A1 (fr)	1983-12-02	Composition pharmaceutique contenant du salbutamol
CH638975A5 (fr)	1983-10-31	Composition medicamenteuse pour le traitement des ulceres gastro-duodenaux.
JP4156793B2 (ja)	2008-09-24	デキサメタゾンゲル
JPS5899414A (ja)	1983-06-13	アルド−スレダクタ−ゼの阻害剤
JP2613113B2 (ja)	1997-05-21	イミダゾール系抗真菌性クリーム製剤
JPH0832626B2 (ja)	1996-03-29	アズレン系抗炎症剤
CA2222566A1 (en)	1996-12-05	Hydrogels that contain sorbic acid
JPS647967B2 (ja)	1989-02-10
Rodu et al.	1988	In vitro virucidal activity components of a forming medication
FR2803515A1 (fr)	2001-07-13	Solution aqueuse stable de deoxyfructosazine
FR2707163A1 (fr)	1995-01-13	Composition hydroalcoolique contenant un parfum.