CH675728A5 - - Google Patents

Download PDF

Info

Publication number
CH675728A5
CH675728A5 CH3210/87A CH321087A CH675728A5 CH 675728 A5 CH675728 A5 CH 675728A5 CH 3210/87 A CH3210/87 A CH 3210/87A CH 321087 A CH321087 A CH 321087A CH 675728 A5 CH675728 A5 CH 675728A5
Authority
CH
Switzerland
Prior art keywords
hiv
thr
peptide
antibodies
arg
Prior art date
Application number
CH3210/87A
Other languages
German (de)
English (en)
Inventor
Mary Kathleen Shriver
Elaine K Thomas
Westley L Cosand
Larry H Gosting
Edna S Dickinson
Janela Mcclure
George J Todaro
Robert C Nowinski
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Publication of CH675728A5 publication Critical patent/CH675728A5/de

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B25/00—Multi-stage pumps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/112—Retroviridae (F), e.g. leukemia viruses
    • C07K16/114—Lentivirus (G), e.g. human immunodeficiency virus [HIV], feline immunodeficiency virus [FIV] or simian immunodeficiency virus [SIV]
    • C07K16/1143—Gag-pol proteins, e.g. p17or p24
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • AIDS & HIV (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Mechanical Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CH3210/87A 1986-08-20 1987-08-20 CH675728A5 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89827386A 1986-08-20 1986-08-20
US4502687A 1987-05-01 1987-05-01
US6799687A 1987-06-29 1987-06-29

Publications (1)

Publication Number Publication Date
CH675728A5 true CH675728A5 (fr) 1990-10-31

Family

ID=27366600

Family Applications (1)

Application Number Title Priority Date Filing Date
CH3210/87A CH675728A5 (fr) 1986-08-20 1987-08-20

Country Status (28)

Country Link
JP (1) JPS6485928A (fr)
KR (1) KR920008744B1 (fr)
AT (1) AT398080B (fr)
AU (1) AU616156B2 (fr)
BE (1) BE1000811A4 (fr)
CH (1) CH675728A5 (fr)
CS (1) CS275838B6 (fr)
DE (1) DE3727703A1 (fr)
DK (1) DK433087A (fr)
ES (1) ES2010727A6 (fr)
FI (1) FI873553L (fr)
FR (1) FR2603107B1 (fr)
GB (1) GB2196634B (fr)
GR (1) GR871298B (fr)
HU (1) HU214439B (fr)
IE (1) IE60671B1 (fr)
IL (1) IL83580A (fr)
IT (1) IT1222518B (fr)
LU (1) LU86972A1 (fr)
NL (1) NL8701950A (fr)
NO (2) NO300462B1 (fr)
NZ (1) NZ221440A (fr)
OA (1) OA08652A (fr)
PL (1) PL155084B1 (fr)
PT (1) PT85567B (fr)
SE (1) SE506025C2 (fr)
YU (1) YU152587A (fr)
ZW (1) ZW15487A1 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP96A (en) * 1986-06-03 1990-08-12 The Usa Dept Of Commerce Small peptides which inhibit binding to T-4 receptors and act as immunogens.
AU625720B2 (en) * 1987-05-01 1992-07-16 Genetic Systems Corporation Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use
US5981278A (en) * 1987-05-29 1999-11-09 Tanox, Inc. Chimeric monoclonal antibodies which neutralize HIV-1 infection and their applications in therapy and prevention for AIDS
EP0366718B1 (fr) * 1987-05-29 1995-05-10 Tanox Biosystems, Inc. Anticorps monoclonaux neutralisant le hiv-1
US6657050B1 (en) 1987-05-29 2003-12-02 Tanox, Inc. Chimeric viral-neutralizing immunoglobulins
US5834599A (en) * 1987-05-29 1998-11-10 Tanox Biosystems, Inc. Immunoconjugates which neutralize HIV-1 infection
JP2569185B2 (ja) * 1988-01-26 1997-01-08 アメリカ合衆国 抗ｈｉｖ応答を喚起する合成抗原
CA1341285C (fr) * 1988-02-12 2001-08-14 Chang Yi Wang Peptides synthetiques servant a la detection d'anticorps de la proteine de surface gp120 du virus hiv, destines au diagnostic du sida, ainsi que d'etats pre-sidatiques, ou aux fins de vaccins
IL90048A0 (en) * 1988-04-25 1989-12-15 Merck & Co Inc Recombinant gag precursor of hiv,its preparation and its use as aids vaccine
US5562905A (en) * 1988-04-26 1996-10-08 E. I. Du Pont De Nemours And Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
EP0339504A3 (fr) * 1988-04-26 1990-09-12 The Du Pont Merck Pharmaceutical Company Virus d'immunodéficience humaine (HIV) peptide env-codé capable de provoquer les anticorps inhibiteurs du HIV dans les mammifères
FR2632310B1 (fr) * 1988-06-06 1992-04-10 Pasteur Institut Peptides ayant des proprietes protectrices d'un virus pathogene du type hiv dans des cellules sensibles
IL91843A0 (en) * 1988-10-03 1990-06-10 Repligen Corp Hiv proteins and peptides useful in the diagnosis,prophylaxis aids or therapy of aids
EP0421626A1 (fr) * 1989-09-19 1991-04-10 Merck & Co. Inc. Vaccin contre le SIDA et l'hépatite B
SE9000333D0 (sv) * 1990-01-31 1990-01-31 Britta Wahren Monoklonal antikropp
SE468168B (sv) * 1990-02-20 1992-11-16 Replico Medical Ab Hiv-1, p24 peptider, diagnostiska antigener och foerfarande foer saerskiljande diagnostik av preliminaert hiv-1 positiva serumprov
JPH03271233A (ja) * 1990-03-19 1991-12-03 Inst Pasteur ウイルスエンベロープ糖タンパク質及びその糖タンパク質の中和エピトープに対応するペプチドの間の相乗作用による、ウイルス性感染に対する防御の誘発
CA2047078A1 (fr) * 1990-07-19 1992-01-20 Steven S. Bondy Peptides cycliques neutralisant le vih
CA2047042A1 (fr) * 1990-07-19 1992-01-20 John Hannah Peptides cycliques neutralisant le vih
JPH05310785A (ja) * 1991-09-30 1993-11-22 Nitto Denko Corp Ｈｉｖ関連環状ペプチドおよびこれを固定化した吸着体
DE69333537T2 (de) * 1992-03-27 2005-06-16 Advanced Immuni T, Inc. T-peptid und damit verwandte Peptide in der Behandlung von entzündungen einschlies slich der Multiplen Sklerose
AU2006322656B2 (en) 2005-12-09 2012-03-08 Vectus Biosystems Limited VIP fragments and methods of use
JP5165751B2 (ja) 2008-09-02 2013-03-21 日本特殊陶業株式会社 スパークプラグ
KR102727239B1 (ko) * 2022-09-07 2024-11-07 한국세라믹기술원 산화 마그네슘　분말 및 그의 제조방법

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9328391B1 (en) * 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
GB8501473D0 (en) * 1985-01-21 1985-02-20 Pasteur Institut Cloned dna sequences
KR930000189B1 (ko) * 1984-10-18 1993-01-11 앵스뛰띠 빠스뙤르 임파선증과 후천성 면역 결핍증 바이러스의 항원을 제조하는 방법 및 이 항원에 대한 항체의 생산 방법
CA1341482C (fr) * 1984-10-31 2005-05-10 Paul A. Luciw Procede de preparation de fragments de retrovirus du groupe du sida
WO1986006099A1 (fr) * 1985-04-08 1986-10-23 Genetic Systems Corporation EXPRESSION ET UTILISATION DIAGNOSTIQUE DE PEPTIDES CODES gag ET IMMUNOLOGIQUEMENT REACTIFS A DES ANTICORPS DU LAV
IE64785B1 (en) * 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
DK171119B1 (da) * 1985-04-19 1996-06-17 Hoffmann La Roche AIDS-viruskappeprotein, ekspressionsvektor bærende viruskappeproteinet, transformanter transformeret med ekspressionsvektoren, fremgangsmåde til fremstilling af viruskappeproteinet, fremgangsmåde til detektion af AIDS-antistoffer, fremgangsmåde til bestemmelse af AIDS-virus, vaccine mod AIDS, antistoffer mod viruskappeproteinet samt anvendelse af dette til fremstilling af en vaccine og til testnin
WO1986006414A1 (fr) * 1985-04-29 1986-11-06 Genetic Systems Corporation Antigenes synthetiques permettant la detection d'une infection apparentee au sida
GB8525615D0 (en) * 1985-10-17 1985-11-20 Hoffmann La Roche Polypeptides
WO1987002775A1 (fr) * 1985-10-24 1987-05-07 Southwest Foundation For Biomedical Research Peptides synthetiques et leur utilisation pour le diagnostic et la vaccination contre le sida et son complexe associe
EP0245459B1 (fr) * 1985-11-07 1993-09-29 The President And Fellows Of Harvard College Proteine de cellules infectees par le virus lymphotrophique des cellules t, et son analyse
US4772547A (en) * 1986-02-03 1988-09-20 Hoffmann-La Roche Inc. HTLV-III envelope peptides
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
US4925784A (en) * 1986-04-04 1990-05-15 Hoffmann-La Roche Inc. Expression and purification of an HTLV-III gag/env gene protein
IE63109B1 (en) * 1986-06-23 1995-03-22 Genetic Systems Corp Human monoclonal antibody to lymphadenopathy-associated virus
EP0525828A3 (en) * 1986-08-01 1993-02-24 Repligen Corporation Recombinant polypeptides and their uses, including assay for aids virus
AU592258B2 (en) * 1986-12-30 1990-01-04 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Synthetic peptides which induce cellular immunity to the aids virus and aids viral proteins

Also Published As

Publication number Publication date
BE1000811A4 (fr) 1989-04-11
PL267401A1 (en) 1988-07-21
ES2010727A6 (es) 1989-12-01
GB2196634B (en) 1991-05-15
HUT44619A (en) 1988-03-28
PT85567A (en) 1987-09-01
AT398080B (de) 1994-09-26
NO300462B1 (no) 1997-06-02
PT85567B (pt) 1991-02-08
GB2196634A (en) 1988-05-05
IL83580A (en) 1992-11-15
IT8721678A0 (it) 1987-08-19
NZ221440A (en) 1991-11-26
OA08652A (fr) 1988-11-30
KR920008744B1 (ko) 1992-10-09
DE3727703A1 (de) 1988-05-05
AU616156B2 (en) 1991-10-24
DK433087A (da) 1988-02-21
FR2603107B1 (fr) 1992-04-24
IL83580A0 (en) 1988-01-31
HU214439B (hu) 1998-03-30
IT1222518B (it) 1990-09-05
FI873553A0 (fi) 1987-08-17
GR871298B (en) 1988-01-12
CS8706136A2 (en) 1990-08-14
NO934897L (no) 1993-12-29
JPS6485928A (en) 1989-03-30
YU152587A (sh) 1992-09-07
ATA208987A (de) 1994-01-15
NO873495D0 (no) 1987-08-19
NO302176B1 (no) 1998-02-02
NO873495L (no) 1988-02-22
SE8703225L (sv) 1988-02-21
SE506025C2 (sv) 1997-11-03
FI873553A7 (fi) 1988-02-21
IE60671B1 (en) 1994-08-10
DK433087D0 (da) 1987-08-19
ZW15487A1 (en) 1988-09-14
FR2603107A1 (fr) 1988-02-26
FI873553L (fi) 1988-02-21
PL155084B1 (en) 1991-10-31
KR890002547A (ko) 1989-04-10
IE872219L (en) 1988-02-20
CS275838B6 (en) 1992-03-18
GB8719587D0 (en) 1987-09-23
SE8703225D0 (sv) 1987-08-19
LU86972A1 (fr) 1988-03-02
AU7720187A (en) 1988-05-19
NL8701950A (nl) 1988-03-16
NO934897D0 (no) 1993-12-29

Similar Documents

Publication Publication Date Title
AT398080B (de) Immortalisierte zellinie, verfahren zu ihrer herstellung und verfahren zur herstellung von monoklonalen antikörpern sowie diagnoseverfahren und -mittel
DE3587181T2 (de) F antigene vom menschlichen immunodefizienz-virus und deren verwendungen.
DE3855947T2 (de) Peptide mit den immunologischen Eigenschaften von HIV-2
US5166050A (en) Monoclonal antibodies and peptides useful in treating and diagnosing HIV infections
DE3853779T2 (de) Hiv-1 neutralisierende monoklonale antikörper.
DE69133242T2 (de) Peptide zur verwendung in impfung und anregung von antikörperbildung gegen menschliches immunschwäche virus
JPH06502539A (ja) Ｈｉｖ−１　ｇｐ１２０のｖ３ループおよびｃｄ−４結合部位に特異的な中和ヒトモノクローナル抗体
JPH05262667A (ja) ウイルス抗原を用いるワクチン
US5854400A (en) Monoclonal antibodies which neutralize HIV-1 infection
JPH05503629A (ja) 抗ウィルス剤及び免疫原として使用される、非複製組換え製レトロウィルス粒子
EP0542998A1 (fr) Vaccin et procede de traitememt contre les infections dues au virus de l'immunodeficience humaine
EP0554446A1 (fr) Anticorps monoclonaux utiles dans la thérapie d'une infection à HIV-1
DE69527708T2 (de) Synthetischer impfstoff zum schutz gegen infektionen mit dem menschlichen immunschwächevirus
AU733234B2 (en) Conjugated peptides, immunological reagent containing same and use thereof for treatment of immunological disorders
DE69433057T2 (de) Peptide zur verwendung bei der impfung und induktion neutralisierender antikörper gegen das menschliche immunschwäche-virus
DE69433787T2 (de) HTLV-I UND HTLV-II gp21 abgeleitete Peptide zur diagnostischen Verwendung
DE69707680T2 (de) Caprin arthritis-enzephalitis virus enthaltende vakzine und verwendung zur immunschutz gegen hiv-1 infektion
US6290963B1 (en) Anti-HIV compositions containing native and recombinant peptides
DD284089A5 (de) Verfahren zur bestimmung der anwesenheit von hiv in einer biologischen probe
DE68925202T2 (de) HIV-2-EHO-Retrovirus-Proteine und -Glycoproteine, Antikörper gegen sie, Verwendung für diagnostische Zwecke
AT403050B (de) Peptide, die antikörper binden
PL161520B1 (pl) Sposób wytwarzania nowego peptydu PL
HU211505A9 (hu) HIV-fertőzés kezelésére szolgáló vakcinakészítmény Az átmeneti oltalom az 1-15. igénypontokra vonatkozik.
AU2004201321A1 (en) Compositions and methods for treating viral infections
SI9200420A (sl) Vakcina proti infekciji, ki jo povzroča človeški virus imunodeficience

Legal Events

Date Code Title Description
PL Patent ceased