CS275838B6 - Method for production of hybridoms used for monoclonal antigen against hiv virus producing - Google Patents

Method for production of hybridoms used for monoclonal antigen against hiv virus producing Download PDF

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Publication number
CS275838B6
CS275838B6 CS876136A CS613687A CS275838B6 CS 275838 B6 CS275838 B6 CS 275838B6 CS 876136 A CS876136 A CS 876136A CS 613687 A CS613687 A CS 613687A CS 275838 B6 CS275838 B6 CS 275838B6
Authority
CS
Czechoslovakia
Prior art keywords
hiv
antibodies
peptide
peptides
virus
Prior art date
Application number
CS876136A
Other languages
Czech (cs)
English (en)
Other versions
CS8706136A2 (en
Inventor
Kathleen Mary Shriver
Elaine K Thomas
Wesley L Cosand
Larry H Gosting
Edna S Dickinson
Janela Mcclure
George J Todaro
Robert C Nowinski
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Publication of CS8706136A2 publication Critical patent/CS8706136A2/cs
Publication of CS275838B6 publication Critical patent/CS275838B6/cs

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B25/00—Multi-stage pumps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/112—Retroviridae (F), e.g. leukemia viruses
    • C07K16/114—Lentivirus (G), e.g. human immunodeficiency virus [HIV], feline immunodeficiency virus [FIV] or simian immunodeficiency virus [SIV]
    • C07K16/1143—Gag-pol proteins, e.g. p17or p24
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Mechanical Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CS876136A 1986-08-20 1987-08-20 Method for production of hybridoms used for monoclonal antigen against hiv virus producing CS275838B6 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89827386A 1986-08-20 1986-08-20
US4502687A 1987-05-01 1987-05-01
US6799687A 1987-06-29 1987-06-29

Publications (2)

Publication Number Publication Date
CS8706136A2 CS8706136A2 (en) 1990-08-14
CS275838B6 true CS275838B6 (en) 1992-03-18

Family

ID=27366600

Family Applications (1)

Application Number Title Priority Date Filing Date
CS876136A CS275838B6 (en) 1986-08-20 1987-08-20 Method for production of hybridoms used for monoclonal antigen against hiv virus producing

Country Status (28)

Country Link
JP (1) JPS6485928A (fr)
KR (1) KR920008744B1 (fr)
AT (1) AT398080B (fr)
AU (1) AU616156B2 (fr)
BE (1) BE1000811A4 (fr)
CH (1) CH675728A5 (fr)
CS (1) CS275838B6 (fr)
DE (1) DE3727703A1 (fr)
DK (1) DK433087A (fr)
ES (1) ES2010727A6 (fr)
FI (1) FI873553L (fr)
FR (1) FR2603107B1 (fr)
GB (1) GB2196634B (fr)
GR (1) GR871298B (fr)
HU (1) HU214439B (fr)
IE (1) IE60671B1 (fr)
IL (1) IL83580A (fr)
IT (1) IT1222518B (fr)
LU (1) LU86972A1 (fr)
NL (1) NL8701950A (fr)
NO (2) NO300462B1 (fr)
NZ (1) NZ221440A (fr)
OA (1) OA08652A (fr)
PL (1) PL155084B1 (fr)
PT (1) PT85567B (fr)
SE (1) SE506025C2 (fr)
YU (1) YU152587A (fr)
ZW (1) ZW15487A1 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP96A (en) * 1986-06-03 1990-08-12 The Usa Dept Of Commerce Small peptides which inhibit binding to T-4 receptors and act as immunogens.
AU625720B2 (en) * 1987-05-01 1992-07-16 Genetic Systems Corporation Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use
US5981278A (en) * 1987-05-29 1999-11-09 Tanox, Inc. Chimeric monoclonal antibodies which neutralize HIV-1 infection and their applications in therapy and prevention for AIDS
DE3853779T2 (de) * 1987-05-29 1995-09-07 Baylor College Medicine Hiv-1 neutralisierende monoklonale antikörper.
US6657050B1 (en) 1987-05-29 2003-12-02 Tanox, Inc. Chimeric viral-neutralizing immunoglobulins
US5834599A (en) * 1987-05-29 1998-11-10 Tanox Biosystems, Inc. Immunoconjugates which neutralize HIV-1 infection
EP0400076B1 (fr) * 1988-01-26 1996-05-15 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Antigene synthetique suscitant une reaction anti-vih
CA1341285C (fr) * 1988-02-12 2001-08-14 Chang Yi Wang Peptides synthetiques servant a la detection d'anticorps de la proteine de surface gp120 du virus hiv, destines au diagnostic du sida, ainsi que d'etats pre-sidatiques, ou aux fins de vaccins
IL90048A0 (en) * 1988-04-25 1989-12-15 Merck & Co Inc Recombinant gag precursor of hiv,its preparation and its use as aids vaccine
EP0339504A3 (fr) * 1988-04-26 1990-09-12 The Du Pont Merck Pharmaceutical Company Virus d'immunodéficience humaine (HIV) peptide env-codé capable de provoquer les anticorps inhibiteurs du HIV dans les mammifères
US5562905A (en) * 1988-04-26 1996-10-08 E. I. Du Pont De Nemours And Company Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals
FR2632310B1 (fr) * 1988-06-06 1992-04-10 Pasteur Institut Peptides ayant des proprietes protectrices d'un virus pathogene du type hiv dans des cellules sensibles
KR900701836A (ko) * 1988-10-03 1990-12-04 라메쉬 엘. 라탄 신규 hiv 단백질 및 aids의 진단, 예방 또는 치료에 유용한 펩티드
EP0421626A1 (fr) * 1989-09-19 1991-04-10 Merck & Co. Inc. Vaccin contre le SIDA et l'hépatite B
SE9000333D0 (sv) * 1990-01-31 1990-01-31 Britta Wahren Monoklonal antikropp
SE468168B (sv) * 1990-02-20 1992-11-16 Replico Medical Ab Hiv-1, p24 peptider, diagnostiska antigener och foerfarande foer saerskiljande diagnostik av preliminaert hiv-1 positiva serumprov
JPH03271233A (ja) * 1990-03-19 1991-12-03 Inst Pasteur ウイルスエンベロープ糖タンパク質及びその糖タンパク質の中和エピトープに対応するペプチドの間の相乗作用による、ウイルス性感染に対する防御の誘発
CA2047042A1 (fr) * 1990-07-19 1992-01-20 John Hannah Peptides cycliques neutralisant le vih
CA2047078A1 (fr) * 1990-07-19 1992-01-20 Steven S. Bondy Peptides cycliques neutralisant le vih
JPH05310785A (ja) * 1991-09-30 1993-11-22 Nitto Denko Corp Ｈｉｖ関連環状ペプチドおよびこれを固定化した吸着体
WO1993020102A1 (fr) * 1992-03-27 1993-10-14 Peptide Technology Limited Peptide t et peptides associes destines au traitement des inflammations, notamment la sclerose en plaques
RU2466738C2 (ru) 2005-12-09 2012-11-20 Вектас Байосистемз Лимитед Фрагменты vip и способы их применения
EP2323233B1 (fr) 2008-09-02 2017-10-11 NGK Spark Plug Co., Ltd. Bougie d allumage
KR102727239B1 (ko) * 2022-09-07 2024-11-07 한국세라믹기술원 산화 마그네슘　분말 및 그의 제조방법

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9328391B1 (en) * 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
DE3587512T2 (de) * 1984-10-18 1993-12-02 Centre Nat Rech Scient Hüllenantigene vom menschlichen Immunodefizienz-Virus und deren Verwendungen.
GB8501473D0 (en) * 1985-01-21 1985-02-20 Pasteur Institut Cloned dna sequences
CA1341423C (fr) * 1984-10-31 2003-03-04 Paul A. Luciw Proteines recombinantes de virus associes au syndrome d'adenopathie et/ou au syndrome d'immuno-deficience acquise
IE64785B1 (en) * 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
GR860915B (en) * 1985-04-08 1986-07-11 Genetic Systems Corp Expression and diagnostic use of gag encoded peptides which are immunologically reactive with antibodies to lav
DK171119B1 (da) * 1985-04-19 1996-06-17 Hoffmann La Roche AIDS-viruskappeprotein, ekspressionsvektor bærende viruskappeproteinet, transformanter transformeret med ekspressionsvektoren, fremgangsmåde til fremstilling af viruskappeproteinet, fremgangsmåde til detektion af AIDS-antistoffer, fremgangsmåde til bestemmelse af AIDS-virus, vaccine mod AIDS, antistoffer mod viruskappeproteinet samt anvendelse af dette til fremstilling af en vaccine og til testnin
KR910002374B1 (ko) * 1985-04-29 1991-04-20 제네틱 시스템즈 코포레이션 Aids 관련질병의 검출을 위한 합성항원
GB8525615D0 (en) * 1985-10-17 1985-11-20 Hoffmann La Roche Polypeptides
EP0245362B1 (fr) * 1985-10-24 1994-06-29 Ronald C. Kennedy Peptides synthetiques et leur utilisation pour le diagnostic et la vaccination contre le sida et son complexe associe
JP2837669B2 (ja) * 1985-11-07 1998-12-16 プレジデント アンド フエロウズ オブ ハ−バ−ド カレツジ Ｔ−細胞リンパ趨行性ウイルス蛋白及びその分析
US4772547A (en) * 1986-02-03 1988-09-20 Hoffmann-La Roche Inc. HTLV-III envelope peptides
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
US4925784A (en) * 1986-04-04 1990-05-15 Hoffmann-La Roche Inc. Expression and purification of an HTLV-III gag/env gene protein
DK169582B1 (da) * 1986-06-23 1994-12-12 Squibb Bristol Myers Co Humant monoklonalt antistof, der er i stand til at reagere med en epitop på LAV/HTLV-III kappeglycoproteinet gp41, cellelinier, som producerer sådant antistof, farmaceutisk præparat indeholdende antistoffet samt fremgangsmåde til bestemmelse af nærværelsen af LAV/HTLV-III i en biologisk prøve og fremgangsmåde til separering af specifikke antigendeterminanter af LAV/HTLV-III under anvendelse af ant
EP0525828A3 (en) * 1986-08-01 1993-02-24 Repligen Corporation Recombinant polypeptides and their uses, including assay for aids virus
DE3787002T2 (de) * 1986-12-30 1993-11-25 Us Health Synthetische Peptide, die zelluläre Immunität gegen den AIDS-Virus und dessen Proteine erzeugen.

Also Published As

Publication number Publication date
IT8721678A0 (it) 1987-08-19
NO934897D0 (no) 1993-12-29
PL267401A1 (en) 1988-07-21
NO300462B1 (no) 1997-06-02
IE60671B1 (en) 1994-08-10
FI873553A0 (fi) 1987-08-17
KR920008744B1 (ko) 1992-10-09
PL155084B1 (en) 1991-10-31
SE8703225D0 (sv) 1987-08-19
NZ221440A (en) 1991-11-26
AU616156B2 (en) 1991-10-24
JPS6485928A (en) 1989-03-30
IL83580A0 (en) 1988-01-31
PT85567A (en) 1987-09-01
OA08652A (fr) 1988-11-30
ES2010727A6 (es) 1989-12-01
HUT44619A (en) 1988-03-28
CS8706136A2 (en) 1990-08-14
NO873495D0 (no) 1987-08-19
LU86972A1 (fr) 1988-03-02
IL83580A (en) 1992-11-15
YU152587A (sh) 1992-09-07
DK433087A (da) 1988-02-21
AU7720187A (en) 1988-05-19
SE8703225L (sv) 1988-02-21
SE506025C2 (sv) 1997-11-03
CH675728A5 (fr) 1990-10-31
GR871298B (en) 1988-01-12
BE1000811A4 (fr) 1989-04-11
ATA208987A (de) 1994-01-15
FI873553A7 (fi) 1988-02-21
DE3727703A1 (de) 1988-05-05
GB2196634A (en) 1988-05-05
PT85567B (pt) 1991-02-08
IE872219L (en) 1988-02-20
KR890002547A (ko) 1989-04-10
NO302176B1 (no) 1998-02-02
NO934897L (no) 1993-12-29
GB2196634B (en) 1991-05-15
AT398080B (de) 1994-09-26
DK433087D0 (da) 1987-08-19
FI873553L (fi) 1988-02-21
FR2603107B1 (fr) 1992-04-24
ZW15487A1 (en) 1988-09-14
FR2603107A1 (fr) 1988-02-26
IT1222518B (it) 1990-09-05
HU214439B (hu) 1998-03-30
NL8701950A (nl) 1988-03-16
GB8719587D0 (en) 1987-09-23
NO873495L (no) 1988-02-22

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