CL2004000366A1 - USO DE UNA COMBINACION DE UN COMPUESTO DERIVADO DE PIRAZOL INHIBIDOR DE QUINASA p38, Y UN INHIBIDOR DE ACE PARA TRATAR DISFUNCION RENAL, ENFERMEDAD CARDIOVASCULAR Y VASCULAR, RETINOPATIA, NEUROPATIA, EDEMA, DISFUNCION ENDOTELIAL O INSULINOPATIA. - Google Patents
USO DE UNA COMBINACION DE UN COMPUESTO DERIVADO DE PIRAZOL INHIBIDOR DE QUINASA p38, Y UN INHIBIDOR DE ACE PARA TRATAR DISFUNCION RENAL, ENFERMEDAD CARDIOVASCULAR Y VASCULAR, RETINOPATIA, NEUROPATIA, EDEMA, DISFUNCION ENDOTELIAL O INSULINOPATIA.Info
- Publication number
- CL2004000366A1 CL2004000366A1 CL200400366A CL2004000366A CL2004000366A1 CL 2004000366 A1 CL2004000366 A1 CL 2004000366A1 CL 200400366 A CL200400366 A CL 200400366A CL 2004000366 A CL2004000366 A CL 2004000366A CL 2004000366 A1 CL2004000366 A1 CL 2004000366A1
- Authority
- CL
- Chile
- Prior art keywords
- quinasa
- combination
- cardiovascular
- neuropatia
- insotunatio
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
USO DE UN INHIBIDOR QUINASA p38 (POR EJEMPLO, UN INHIBIDOR DE QUINASA p38 D EPIRAZOL SUSTITUIDO) Y UNA COMBINACION DE UN INHIBIDOR DE QUINASA p38 CON UN INHIBIDOR DE ENZIMA CONVERTIDORA DE ANGIOTENSINA (ACE) UTILES PARA PREPARAR UN MEDICAMENTO PARA TRATAR UNA CONDICION CARDIOVASCULAR, ES DECIR, HIPERTENSION O FALLA CARDIACA O UNA CONDICION ASOCIADA CON UNA CONDICION CARDIOVASCULAR. COMPRENDE TAMBIEN COMPOSICIONES FARMACEUTICAS QUE CONTIENEN LAS ANTEDICHAS COMBINACIONES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45052903P | 2003-02-26 | 2003-02-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2004000366A1 true CL2004000366A1 (es) | 2005-01-07 |
Family
ID=32927663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL200400366A CL2004000366A1 (es) | 2003-02-26 | 2004-02-25 | USO DE UNA COMBINACION DE UN COMPUESTO DERIVADO DE PIRAZOL INHIBIDOR DE QUINASA p38, Y UN INHIBIDOR DE ACE PARA TRATAR DISFUNCION RENAL, ENFERMEDAD CARDIOVASCULAR Y VASCULAR, RETINOPATIA, NEUROPATIA, EDEMA, DISFUNCION ENDOTELIAL O INSULINOPATIA. |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US20040167197A1 (es) |
| CL (1) | CL2004000366A1 (es) |
| TW (2) | TW200508226A (es) |
| WO (2) | WO2004075852A2 (es) |
Families Citing this family (26)
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| US6979686B1 (en) * | 2001-12-07 | 2005-12-27 | Pharmacia Corporation | Substituted pyrazoles as p38 kinase inhibitors |
| WO2005061486A1 (en) * | 2003-12-19 | 2005-07-07 | Pharmacia Corporation | Crystalline form of 2-{4-‘3-(4-chloro-2-fluorophenyl)-4-pyrimidin-4-yl-1h-pyrazol-5-yl!piperidin-1-yl}-2-oxoethanol |
| GB0405381D0 (en) * | 2004-03-10 | 2004-04-21 | Univ Wales Medicine | A method and means for treating heart failure |
| EP1778686B9 (en) * | 2004-08-12 | 2009-07-08 | Pfizer Limited | Triazolopyridinylsulfanyl derivatives as p38 map kinase inhibitors |
| DE602005020462D1 (de) * | 2004-08-25 | 2010-05-20 | Essentialis Inc | Pharmazeutische formulierungen von kalium-atp-kanalöffnern und deren verwendungen |
| US20060281791A1 (en) * | 2005-04-29 | 2006-12-14 | Children's Medical Center Corporation | Methods of increasing proliferation of adult mammalian cardiomyocytes through p38 map kinase inhibition |
| US7799777B2 (en) | 2006-01-05 | 2010-09-21 | Essentialis, Inc. | Salts of potassium ATP channel openers and uses thereof |
| AU2012203517B2 (en) * | 2006-01-05 | 2014-04-24 | Soleno Therapeutics, Inc. | Salts of potassium ATP channel openers and uses thereof |
| ES2329419T3 (es) | 2006-01-31 | 2009-11-25 | F. Hoffmann-La Roche Ag | 7h-pirido(3,4-d)pirimidin-8-onas, su preparacion y uso como inhibidores de proteinas cinasas. |
| US9090604B2 (en) | 2006-07-27 | 2015-07-28 | E I Du Pont De Nemours And Company | Fungicidal azocyclic amides |
| WO2008013622A2 (en) * | 2006-07-27 | 2008-01-31 | E. I. Du Pont De Nemours And Company | Fungicidal azocyclic amides |
| US8293481B2 (en) * | 2006-11-10 | 2012-10-23 | Mayo Foundation For Medical Education And Research | Biomarkers for chronic vascular dysfunction |
| MX2009013176A (es) * | 2007-06-05 | 2011-03-02 | Western States Biopharmaceuticals Inc | Moleculas superficiales que inducen citosinas de celulas t y metodos de uso. |
| US20080318909A1 (en) * | 2007-06-14 | 2008-12-25 | Sparagna Genevieve C | Use Of Linoleic Compounds Against Heart Failure |
| FR2917975B1 (fr) * | 2007-06-26 | 2009-10-16 | Ceva Sante Animale Sa | Compositions et traitement de l'insuffisance cardiaque chez les animaux mammiferes non humains |
| CN101795691A (zh) * | 2007-07-02 | 2010-08-04 | 伊森舍丽斯有限公司 | 钾atp通道开放剂的盐及其用途 |
| JP2010533147A (ja) * | 2007-07-13 | 2010-10-21 | アデックス ファルマ エス.エイ. | 代謝調節型グルタミン酸レセプターのモジュレーターとしてのピラゾール誘導体 |
| FR2921063B1 (fr) * | 2007-09-13 | 2009-12-11 | Sod Conseils Rech Applic | Ligands des recepteurs cannabinoides |
| US20090270356A1 (en) * | 2008-04-28 | 2009-10-29 | Ceva Sante Animale Sa | Compositions and treatments of heart failure in non-human mammal animals |
| GB0908193D0 (en) | 2009-05-13 | 2009-06-24 | Albright Patents | Treatment of disease state |
| AU2009346606B2 (en) | 2009-05-20 | 2016-06-02 | Heart Metabolics Limited | Treatment of heart failure with normal ejection fraction |
| TWI730959B (zh) | 2015-05-19 | 2021-06-21 | 英商葛蘭素史克智慧財產發展有限公司 | 作為激酶抑制劑之雜環醯胺 |
| US10286036B2 (en) | 2017-05-12 | 2019-05-14 | Aurinia Pharmaceuticals Inc. | Protocol for treatment of lupus nephritis |
| US20190224275A1 (en) | 2017-05-12 | 2019-07-25 | Aurinia Pharmaceuticals Inc. | Protocol for treatment of lupus nephritis |
| WO2018224037A1 (zh) * | 2017-06-09 | 2018-12-13 | 南京明德新药研发股份有限公司 | 作为at2r受体拮抗剂的羧酸衍生物 |
| WO2025254418A1 (ko) * | 2024-06-03 | 2025-12-11 | 동아에스티 주식회사 | 아미노피리미딘 유도체의 결정다형 및 이의 제조방법 |
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| IL58849A (en) * | 1978-12-11 | 1983-03-31 | Merck & Co Inc | Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them |
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| US20040082551A1 (en) * | 2002-06-05 | 2004-04-29 | Benson Alan G. | Novel pyrazoles and their use as p38 kinase inhibitors |
-
2004
- 2004-02-25 CL CL200400366A patent/CL2004000366A1/es unknown
- 2004-02-26 TW TW093104934A patent/TW200508226A/zh unknown
- 2004-02-26 WO PCT/US2004/005609 patent/WO2004075852A2/en not_active Ceased
- 2004-02-26 TW TW093104944A patent/TW200500361A/zh unknown
- 2004-02-26 WO PCT/US2004/005799 patent/WO2004075857A2/en not_active Ceased
- 2004-02-26 US US10/788,220 patent/US20040167197A1/en not_active Abandoned
- 2004-02-26 US US10/787,721 patent/US20050203072A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| TW200500361A (en) | 2005-01-01 |
| WO2004075857A2 (en) | 2004-09-10 |
| US20040167197A1 (en) | 2004-08-26 |
| WO2004075857A3 (en) | 2005-08-18 |
| US20050203072A1 (en) | 2005-09-15 |
| WO2004075852A2 (en) | 2004-09-10 |
| TW200508226A (en) | 2005-03-01 |
| WO2004075852A3 (en) | 2005-07-28 |
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