CL2013003229A1 - Compuestos inhibidores del virus de la hepatitis c (vhc); composicion farmaceutica que los comprende; y uso en el tratamiento de una infeccion por vhc. - Google Patents
Compuestos inhibidores del virus de la hepatitis c (vhc); composicion farmaceutica que los comprende; y uso en el tratamiento de una infeccion por vhc.Info
- Publication number
- CL2013003229A1 CL2013003229A1 CL2013003229A CL2013003229A CL2013003229A1 CL 2013003229 A1 CL2013003229 A1 CL 2013003229A1 CL 2013003229 A CL2013003229 A CL 2013003229A CL 2013003229 A CL2013003229 A CL 2013003229A CL 2013003229 A1 CL2013003229 A1 CL 2013003229A1
- Authority
- CL
- Chile
- Prior art keywords
- vhc
- hepatitis
- virus
- infection
- treatment
- Prior art date
Links
- 241000711549 Hepacivirus C Species 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161485224P | 2011-05-12 | 2011-05-12 | |
| US13/465,298 US9546160B2 (en) | 2011-05-12 | 2012-05-07 | Hepatitis C virus inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2013003229A1 true CL2013003229A1 (es) | 2014-09-05 |
Family
ID=46147738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2013003229A CL2013003229A1 (es) | 2011-05-12 | 2013-11-11 | Compuestos inhibidores del virus de la hepatitis c (vhc); composicion farmaceutica que los comprende; y uso en el tratamiento de una infeccion por vhc. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9546160B2 (es) |
| EP (1) | EP2707365B1 (es) |
| JP (1) | JP5977819B2 (es) |
| KR (1) | KR20140037114A (es) |
| CN (1) | CN103827108B (es) |
| AR (1) | AR086389A1 (es) |
| AU (1) | AU2012253578A1 (es) |
| BR (1) | BR112013028679A2 (es) |
| CA (1) | CA2835688A1 (es) |
| CL (1) | CL2013003229A1 (es) |
| CO (1) | CO6821952A2 (es) |
| EA (1) | EA024201B1 (es) |
| IL (1) | IL229331A0 (es) |
| MA (1) | MA35104B1 (es) |
| MX (1) | MX2013012870A (es) |
| PE (1) | PE20150105A1 (es) |
| PH (1) | PH12013502177A1 (es) |
| SG (1) | SG194846A1 (es) |
| TW (1) | TW201249834A (es) |
| UY (1) | UY34066A (es) |
| WO (1) | WO2012154777A1 (es) |
| ZA (1) | ZA201309356B (es) |
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| US8303944B2 (en) * | 2006-08-11 | 2012-11-06 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US8552047B2 (en) | 2011-02-07 | 2013-10-08 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US9326973B2 (en) | 2012-01-13 | 2016-05-03 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| CN104884455B (zh) * | 2012-10-24 | 2017-09-12 | 百时美施贵宝公司 | 丙型肝炎病毒抑制剂 |
| US9717712B2 (en) | 2013-07-02 | 2017-08-01 | Bristol-Myers Squibb Company | Combinations comprising tricyclohexadecahexaene derivatives for use in the treatment of hepatitis C virus |
| US20150023913A1 (en) | 2013-07-02 | 2015-01-22 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| US9775831B2 (en) | 2013-07-17 | 2017-10-03 | Bristol-Myers Squibb Company | Combinations comprising biphenyl derivatives for use in the treatment of HCV |
| EP3080104A1 (en) * | 2013-12-11 | 2016-10-19 | Bristol-Myers Squibb Company | 4,4'-biphenyldiyl-bis-(1 h-imidazolyl) derivatives as hepatitis hcv inhibitors |
| CN104725365B (zh) * | 2013-12-23 | 2019-02-26 | 南京圣和药业股份有限公司 | 丙型肝炎病毒抑制剂及其应用 |
| CN104860931A (zh) * | 2014-02-21 | 2015-08-26 | 常州寅盛药业有限公司 | 丙肝病毒抑制剂及其制药用途 |
| WO2017023631A1 (en) | 2015-08-06 | 2017-02-09 | Bristol-Myers Squibb Company | Hepatitis c virus inhibitors |
| CN115073308A (zh) * | 2021-03-15 | 2022-09-20 | 苏州信礼发医药技术有限公司 | 1-氨甲基-1-环丙醇的合成方法 |
| CA3226162A1 (en) | 2021-07-09 | 2023-01-12 | Plexium, Inc. | Aryl compounds and pharmaceutical compositions that modulate ikzf2 |
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-
2012
- 2012-05-07 US US13/465,298 patent/US9546160B2/en active Active
- 2012-05-09 PE PE2013002484A patent/PE20150105A1/es not_active Application Discontinuation
- 2012-05-09 BR BR112013028679A patent/BR112013028679A2/pt not_active IP Right Cessation
- 2012-05-09 JP JP2014510419A patent/JP5977819B2/ja not_active Expired - Fee Related
- 2012-05-09 CA CA2835688A patent/CA2835688A1/en not_active Abandoned
- 2012-05-09 WO PCT/US2012/037012 patent/WO2012154777A1/en not_active Ceased
- 2012-05-09 PH PH1/2013/502177A patent/PH12013502177A1/en unknown
- 2012-05-09 EA EA201391685A patent/EA024201B1/ru not_active IP Right Cessation
- 2012-05-09 SG SG2013082730A patent/SG194846A1/en unknown
- 2012-05-09 CN CN201280034345.8A patent/CN103827108B/zh not_active Expired - Fee Related
- 2012-05-09 AU AU2012253578A patent/AU2012253578A1/en not_active Abandoned
- 2012-05-09 MX MX2013012870A patent/MX2013012870A/es unknown
- 2012-05-09 EP EP12723010.0A patent/EP2707365B1/en not_active Not-in-force
- 2012-05-09 KR KR1020137032604A patent/KR20140037114A/ko not_active Withdrawn
- 2012-05-11 TW TW101116982A patent/TW201249834A/zh unknown
- 2012-05-11 AR ARP120101698A patent/AR086389A1/es unknown
- 2012-05-11 UY UY0001034066A patent/UY34066A/es unknown
-
2013
- 2013-11-07 IL IL229331A patent/IL229331A0/en unknown
- 2013-11-07 MA MA36399A patent/MA35104B1/fr unknown
- 2013-11-11 CL CL2013003229A patent/CL2013003229A1/es unknown
- 2013-12-09 CO CO13288206A patent/CO6821952A2/es not_active Application Discontinuation
- 2013-12-11 ZA ZA2013/09356A patent/ZA201309356B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PE20150105A1 (es) | 2015-02-06 |
| CN103827108A (zh) | 2014-05-28 |
| JP2014513690A (ja) | 2014-06-05 |
| UY34066A (es) | 2012-11-30 |
| MX2013012870A (es) | 2014-02-20 |
| JP5977819B2 (ja) | 2016-08-24 |
| CO6821952A2 (es) | 2013-12-31 |
| PH12013502177A1 (en) | 2014-01-13 |
| EA024201B1 (ru) | 2016-08-31 |
| TW201249834A (en) | 2012-12-16 |
| SG194846A1 (en) | 2013-12-30 |
| WO2012154777A1 (en) | 2012-11-15 |
| AR086389A1 (es) | 2013-12-11 |
| CN103827108B (zh) | 2018-05-15 |
| US20130121957A1 (en) | 2013-05-16 |
| CA2835688A1 (en) | 2012-11-15 |
| EA201391685A1 (ru) | 2014-03-31 |
| US9546160B2 (en) | 2017-01-17 |
| IL229331A0 (en) | 2014-01-30 |
| BR112013028679A2 (pt) | 2017-01-24 |
| AU2012253578A1 (en) | 2014-01-16 |
| ZA201309356B (en) | 2015-05-27 |
| MA35104B1 (fr) | 2014-05-02 |
| KR20140037114A (ko) | 2014-03-26 |
| EP2707365A1 (en) | 2014-03-19 |
| EP2707365B1 (en) | 2018-10-17 |
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