CL2014001963A1 - Anticuerpo contra la molecula de guia repulsiva (rgma); composición que la comprende y método para el diagnóstico y el tratamiento de las enfermedades asociadas a la degeneración de las neuritas. - Google Patents

Anticuerpo contra la molecula de guia repulsiva (rgma); composición que la comprende y método para el diagnóstico y el tratamiento de las enfermedades asociadas a la degeneración de las neuritas.

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Publication number
CL2014001963A1
CL2014001963A1 CL2014001963A CL2014001963A CL2014001963A1 CL 2014001963 A1 CL2014001963 A1 CL 2014001963A1 CL 2014001963 A CL2014001963 A CL 2014001963A CL 2014001963 A CL2014001963 A CL 2014001963A CL 2014001963 A1 CL2014001963 A1 CL 2014001963A1
Authority
CL
Chile
Prior art keywords
rgma
neurites
degeneration
diagnosis
treatment
Prior art date
Application number
CL2014001963A
Other languages
English (en)
Inventor
Yuliya Kutskova
John Memmott
Bernhard Mueller
Lili Huang
Philip D Bardwell
Original Assignee
Abbvie Deustschland Gmbh & Co Kg
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Deustschland Gmbh & Co Kg, Abbvie Inc filed Critical Abbvie Deustschland Gmbh & Co Kg
Publication of CL2014001963A1 publication Critical patent/CL2014001963A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K51/1018—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against material from animals or humans
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    • A61K51/04—Organic compounds
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C07K2317/55—Fab or Fab'
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CL2014001963A 2012-01-27 2014-07-24 Anticuerpo contra la molecula de guia repulsiva (rgma); composición que la comprende y método para el diagnóstico y el tratamiento de las enfermedades asociadas a la degeneración de las neuritas. CL2014001963A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261591324P 2012-01-27 2012-01-27

Publications (1)

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CL2014001963A1 true CL2014001963A1 (es) 2014-12-26

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CL2014001963A CL2014001963A1 (es) 2012-01-27 2014-07-24 Anticuerpo contra la molecula de guia repulsiva (rgma); composición que la comprende y método para el diagnóstico y el tratamiento de las enfermedades asociadas a la degeneración de las neuritas.

Country Status (35)

Country Link
US (6) US20130330347A1 (es)
EP (3) EP2807192B1 (es)
JP (4) JP6271441B2 (es)
KR (1) KR102129234B1 (es)
CN (2) CN107880124B (es)
AU (4) AU2013211939C1 (es)
BR (1) BR112014018592B1 (es)
CA (1) CA2857967C (es)
CL (1) CL2014001963A1 (es)
CO (1) CO7020876A2 (es)
CR (1) CR20140360A (es)
CY (1) CY1120390T1 (es)
DK (1) DK2807192T3 (es)
DO (1) DOP2014000174A (es)
EC (1) ECSP14010817A (es)
ES (1) ES2676725T3 (es)
GT (1) GT201400162A (es)
HR (1) HRP20181087T1 (es)
HU (1) HUE039611T2 (es)
IL (7) IL305223A (es)
LT (1) LT2807192T (es)
MX (3) MX352772B (es)
MY (2) MY176695A (es)
NZ (2) NZ714482A (es)
PE (2) PE20190907A1 (es)
PH (1) PH12014501682B1 (es)
PL (1) PL2807192T3 (es)
PT (1) PT2807192T (es)
RS (1) RS57603B1 (es)
RU (2) RU2644337C2 (es)
SG (3) SG11201404263TA (es)
SI (1) SI2807192T1 (es)
TR (1) TR201809967T4 (es)
UA (1) UA118083C2 (es)
WO (1) WO2013112922A1 (es)

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WO2017044862A1 (en) * 2015-09-11 2017-03-16 Abbvie Inc. Methods for treating relapsing forms of multiple sclerosis
WO2017161327A1 (en) * 2016-03-17 2017-09-21 Diazyme Laboratories, Inc. Use of fusion proteins to improve the availability of antigenic peptide epitopes in immunoassays
EP3448874A4 (en) 2016-04-29 2020-04-22 Voyager Therapeutics, Inc. COMPOSITIONS FOR TREATING A DISEASE
EP3448987A4 (en) 2016-04-29 2020-05-27 Voyager Therapeutics, Inc. COMPOSITIONS FOR TREATING A DISEASE
CN109496218A (zh) * 2016-06-01 2019-03-19 艾伯维公司 用于治疗脊髓损伤和疼痛的抗反义导向分子a（rgma）拮抗性抗体
GB201618432D0 (en) * 2016-11-01 2016-12-14 Matn Scient Ltd Detection and treatment of demyelinating diseases
CN108558997B (zh) * 2017-10-20 2021-10-08 中国人民解放军第四军医大学 一种重组融合蛋白TIGIT-Fc及其抗移植排斥反应的应用
US20210269516A1 (en) * 2018-07-10 2021-09-02 Mitsubishi Tanabe Pharma Corporation Prevention or treatment method for peripheral neuropathy or pain accompanying disease in which peripheral neuropathy or astrocyte disorder is recognized
AR120898A1 (es) 2019-12-26 2022-03-30 Univ Osaka Agente para tratar o prevenir neuromielitis óptica en fase aguda
WO2021145432A1 (ja) 2020-01-15 2021-07-22 国立大学法人大阪大学 糖尿病性自律神経障害の予防又は治療剤
CN114945385A (zh) * 2020-01-15 2022-08-26 国立大学法人大阪大学 痴呆症的预防或治疗剂
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TW202434285A (zh) 2022-11-07 2024-09-01 國立大學法人大阪大學 與異常蛋白質之聚集體形成相關之疾病的預防或治療劑
CN121925273A (zh) * 2023-09-29 2026-04-24 田边制药株式会社 由脊髄或脑的障碍引起的疾病所相伴的伴随症状的预防或治疗剂

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