CL2015000209A1 - Compuestos arilos biciclicos sustituidos, modulares de autotaxina (atx); composicion farmaceutica que los comprende; metodo para prevenir, tratar o reducir los sintomas de una condicion seleccionada de un trastorno inflamatorio, autoinmune, fibrosis de pulmon o una malignidad de pulmon. - Google Patents

Compuestos arilos biciclicos sustituidos, modulares de autotaxina (atx); composicion farmaceutica que los comprende; metodo para prevenir, tratar o reducir los sintomas de una condicion seleccionada de un trastorno inflamatorio, autoinmune, fibrosis de pulmon o una malignidad de pulmon.

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Publication number
CL2015000209A1
CL2015000209A1 CL2015000209A CL2015000209A CL2015000209A1 CL 2015000209 A1 CL2015000209 A1 CL 2015000209A1 CL 2015000209 A CL2015000209 A CL 2015000209A CL 2015000209 A CL2015000209 A CL 2015000209A CL 2015000209 A1 CL2015000209 A1 CL 2015000209A1
Authority
CL
Chile
Prior art keywords
autotaxin
atx
symptoms
modular
inflammatory
Prior art date
Application number
CL2015000209A
Other languages
English (en)
Inventor
Sha Mi
Bin Ma
Kevin Guckian
Deping Wang
Lei Zhang
Gnanasambandam Kumaravel
Hairuo Peng
Zhaohul Shao
Lihong Sun
Arthur Taveras
Zhili Xin
Original Assignee
Biogen Idec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49997862&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2015000209(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Idec Inc filed Critical Biogen Idec Inc
Publication of CL2015000209A1 publication Critical patent/CL2015000209A1/es

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    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
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    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
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    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/22—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by carbon atoms having at least two bonds to oxygen atoms
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CL2015000209A 2012-07-27 2015-01-27 Compuestos arilos biciclicos sustituidos, modulares de autotaxina (atx); composicion farmaceutica que los comprende; metodo para prevenir, tratar o reducir los sintomas de una condicion seleccionada de un trastorno inflamatorio, autoinmune, fibrosis de pulmon o una malignidad de pulmon. CL2015000209A1 (es)

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