CL2015003602A1 - Composiciones y métodos para tratar anemia. - Google Patents

Composiciones y métodos para tratar anemia.

Info

Publication number
CL2015003602A1
CL2015003602A1 CL2015003602A CL2015003602A CL2015003602A1 CL 2015003602 A1 CL2015003602 A1 CL 2015003602A1 CL 2015003602 A CL2015003602 A CL 2015003602A CL 2015003602 A CL2015003602 A CL 2015003602A CL 2015003602 A1 CL2015003602 A1 CL 2015003602A1
Authority
CL
Chile
Prior art keywords
treat anemia
compositions
methods
hif
alfa
Prior art date
Application number
CL2015003602A
Other languages
English (en)
Inventor
Robert Shalwitz
Charlotte Hartman
Akshay Buch
Isaiah Shalwitz
John Janusz
Joseph Gardner
Original Assignee
Akebia Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52022903&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2015003602(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akebia Therapeutics Inc filed Critical Akebia Therapeutics Inc
Publication of CL2015003602A1 publication Critical patent/CL2015003602A1/es
Priority to CL2018002372A priority Critical patent/CL2018002372A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1816—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pyridine Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

FORMA DE DOSIFICACION QUE COMPRENDE ACIDO {[5-(3-CLOROFENIL)-3-HIDROXIPIRIDIN-2-CARBONIL]AMINO}-ACETICO; USO PARA TRATAR ANEMIA; METODO PARA TRATAR ANEMIA; USO DE UN INHIBIDOR DE HIF PROLIL HIDROXILASA O ESTABILIZADOR DE HIF-ALFA; USO PARA INCREMENTAR LA PRODUCCION DE EPO ENDOGENA E INDUCIR RESPUESTA; COMPOSICION FARMACEUTICA.
CL2015003602A 2013-06-13 2015-12-11 Composiciones y métodos para tratar anemia. CL2015003602A1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CL2018002372A CL2018002372A1 (es) 2013-06-13 2018-08-17 Composiciones y métodos para tratar anemia (divisional solicitud 201503602)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361834808P 2013-06-13 2013-06-13
US201361889478P 2013-10-10 2013-10-10
US201361898885P 2013-11-01 2013-11-01
US201361898890P 2013-11-01 2013-11-01
US201361912185P 2013-12-05 2013-12-05

Publications (1)

Publication Number Publication Date
CL2015003602A1 true CL2015003602A1 (es) 2016-07-29

Family

ID=52022903

Family Applications (2)

Application Number Title Priority Date Filing Date
CL2015003602A CL2015003602A1 (es) 2013-06-13 2015-12-11 Composiciones y métodos para tratar anemia.
CL2018002372A CL2018002372A1 (es) 2013-06-13 2018-08-17 Composiciones y métodos para tratar anemia (divisional solicitud 201503602)

Family Applications After (1)

Application Number Title Priority Date Filing Date
CL2018002372A CL2018002372A1 (es) 2013-06-13 2018-08-17 Composiciones y métodos para tratar anemia (divisional solicitud 201503602)

Country Status (37)

Country Link
US (2) US11857543B2 (es)
EP (2) EP3007695B1 (es)
JP (6) JP2016521747A (es)
KR (4) KR102660040B1 (es)
CN (3) CN114404413A (es)
AU (4) AU2014278543B2 (es)
BR (1) BR112015031027A2 (es)
CA (2) CA2914662C (es)
CL (2) CL2015003602A1 (es)
CY (2) CY1126699T1 (es)
DK (1) DK3007695T3 (es)
DO (1) DOP2015000297A (es)
EC (1) ECSP20058592A (es)
ES (1) ES2974273T3 (es)
FI (2) FI3007695T3 (es)
FR (1) FR24C1025I2 (es)
HR (1) HRP20240319T1 (es)
HU (2) HUE066123T2 (es)
IL (3) IL243047B (es)
LT (2) LT3007695T (es)
MX (3) MX391198B (es)
MY (1) MY204336A (es)
NL (1) NL301278I2 (es)
NO (1) NO2024025I1 (es)
NZ (3) NZ753905A (es)
PE (2) PE20201496A1 (es)
PH (2) PH12015502738B1 (es)
PL (1) PL3007695T3 (es)
PT (1) PT3007695T (es)
RS (1) RS65341B1 (es)
RU (2) RU2705206C2 (es)
SG (2) SG11201509998WA (es)
SI (1) SI3007695T1 (es)
SM (1) SMT202400092T1 (es)
TW (4) TWI650126B (es)
WO (1) WO2014200773A2 (es)
ZA (1) ZA201509024B (es)

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SMT202400092T1 (it) 2013-06-13 2024-05-14 Akebia Therapeutics Inc Composizioni e metodi per il trattamento dell'anemia
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HK1247201A1 (zh) 2015-01-23 2018-09-21 阿克比治疗有限公司 2-(5-(3-氟苯基)-3-羟基吡啶甲醯胺)乙酸的固体形式、其组合物及用途
PL3277270T3 (pl) * 2015-04-01 2022-02-14 Akebia Therapeutics, Inc. Kompozycje i sposoby leczenia niedokrwistości
CN108401429A (zh) * 2016-12-06 2018-08-14 深圳市塔吉瑞生物医药有限公司 一种取代的杂芳基酰胺化合物及包含该化合物的组合物及其用途
WO2019028150A1 (en) * 2017-08-01 2019-02-07 Akebia Therapeutics, Inc. COMPOSITIONS FOR USE IN METHODS OF TREATING HEMOGLOBINOPATHIES
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JP2023501221A (ja) 2019-10-31 2023-01-18 アケビア セラピューティクス インコーポレイテッド バダデュスタットを使用する治療方法
US11524939B2 (en) 2019-11-13 2022-12-13 Akebia Therapeutics, Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid
US12612367B2 (en) 2019-12-10 2026-04-28 Akebia Therapeutics, Inc. Method for producing nitrogen-containing heteroarylcarboxamide acetic acid derivative
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JP2023524035A (ja) * 2020-04-29 2023-06-08 バイオエイジ ラブス， インコーポレイテッド 加齢性状態を処置するための低酸素誘導因子プロリルヒドロキシラーゼ阻害剤
WO2021257800A1 (en) 2020-06-19 2021-12-23 Akebia Therapeutics, Inc. Modulation of drug-drug interactions of vadadustat
AU2022206302A1 (en) * 2021-01-08 2023-08-17 Akebia Therapeutics, Inc. Therapeutic methods using vadadustat
WO2022150623A1 (en) 2021-01-08 2022-07-14 Akebia Therapeutics, Inc. Compounds and composition for the treatment of anemia
WO2022187142A1 (en) 2021-03-01 2022-09-09 Akebia Therapeutics, Inc. Modulation of drug-drug interactions of vadadustat
EP4308120A4 (en) 2021-03-19 2024-11-27 Zydus Lifesciences Limited TREATMENT OF SICKLE CELL ANEMIA

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