CL2015003801A1 - Formulaciones de anticuerpos y metodos - Google Patents

Formulaciones de anticuerpos y metodos

Info

Publication number
CL2015003801A1
CL2015003801A1 CL2015003801A CL2015003801A CL2015003801A1 CL 2015003801 A1 CL2015003801 A1 CL 2015003801A1 CL 2015003801 A CL2015003801 A CL 2015003801A CL 2015003801 A CL2015003801 A CL 2015003801A CL 2015003801 A1 CL2015003801 A1 CL 2015003801A1
Authority
CL
Chile
Prior art keywords
methods
antibody formulations
antibody
synucleipathy
liofilized
Prior art date
Application number
CL2015003801A
Other languages
English (en)
Inventor
Patrick Garidel
Andreas Langer
Michael Grundman
Original Assignee
Prothena Biosciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51355583&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2015003801(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Prothena Biosciences Ltd filed Critical Prothena Biosciences Ltd
Publication of CL2015003801A1 publication Critical patent/CL2015003801A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Analytical Chemistry (AREA)
  • Inorganic Chemistry (AREA)

Abstract

FORMULACION FARMACÉUTICA QUE COMPRENDE ANTICUERPO 9E4; FORMULACIÓN LIOFILIZADA DE ANTICUERPO 9E4; USO PARA TRATAR SINUCLEIPATÍA, TAL COMO ENFERMEDAD DE PARKINSON; Y MÉTODO DE PURIFICACIÓN DE ANTICUERPO.
CL2015003801A 2013-07-04 2015-12-31 Formulaciones de anticuerpos y metodos CL2015003801A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361843011P 2013-07-04 2013-07-04
US201461979886P 2014-04-15 2014-04-15

Publications (1)

Publication Number Publication Date
CL2015003801A1 true CL2015003801A1 (es) 2016-07-15

Family

ID=51355583

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015003801A CL2015003801A1 (es) 2013-07-04 2015-12-31 Formulaciones de anticuerpos y metodos

Country Status (17)

Country Link
US (2) US10513555B2 (es)
EP (2) EP3524264A1 (es)
JP (3) JP6404338B2 (es)
KR (1) KR20160030247A (es)
CN (1) CN105492019B (es)
AU (1) AU2014285719A1 (es)
CA (1) CA2917097C (es)
CL (1) CL2015003801A1 (es)
CU (2) CU20170039A7 (es)
ES (1) ES2704440T3 (es)
IL (1) IL243425A0 (es)
MX (1) MX2016000201A (es)
PE (1) PE20160868A1 (es)
PH (1) PH12015502788A1 (es)
RU (1) RU2016103079A (es)
SG (1) SG11201510601TA (es)
WO (1) WO2015001504A2 (es)

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US10562973B2 (en) 2014-04-08 2020-02-18 Prothena Bioscience Limited Blood-brain barrier shuttles containing antibodies recognizing alpha-synuclein
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Also Published As

Publication number Publication date
ES2704440T3 (es) 2019-03-18
EP3524264A1 (en) 2019-08-14
JP2019011339A (ja) 2019-01-24
EP3016677B1 (en) 2018-12-19
CU20170039A7 (es) 2017-06-05
EP3016677A2 (en) 2016-05-11
CA2917097A1 (en) 2015-01-08
JP2016534052A (ja) 2016-11-04
PE20160868A1 (es) 2016-09-24
JP6854266B2 (ja) 2021-04-07
CU20160001A7 (es) 2016-08-31
WO2015001504A2 (en) 2015-01-08
WO2015001504A3 (en) 2015-08-06
PH12015502788A1 (en) 2016-03-21
AU2014285719A1 (en) 2016-01-21
JP2021020941A (ja) 2021-02-18
HK1223544A1 (zh) 2017-08-04
US10513555B2 (en) 2019-12-24
US20150079074A1 (en) 2015-03-19
CA2917097C (en) 2022-05-03
CN105492019A (zh) 2016-04-13
RU2016103079A (ru) 2017-08-07
MX2016000201A (es) 2016-05-31
SG11201510601TA (en) 2016-01-28
IL243425A0 (en) 2016-03-31
US20200140534A1 (en) 2020-05-07
KR20160030247A (ko) 2016-03-16
JP6404338B2 (ja) 2018-10-10
CN105492019B (zh) 2020-02-11

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