|
US4179337A
(en)
|
1973-07-20 |
1979-12-18 |
Davis Frank F |
Non-immunogenic polypeptides
|
|
US4275149A
(en)
|
1978-11-24 |
1981-06-23 |
Syva Company |
Macromolecular environment control in specific receptor assays
|
|
US4318980A
(en)
|
1978-04-10 |
1982-03-09 |
Miles Laboratories, Inc. |
Heterogenous specific binding assay employing a cycling reactant as label
|
|
JPS6023084B2
(ja)
|
1979-07-11 |
1985-06-05 |
味の素株式会社 |
代用血液
|
|
WO1981001145A1
(en)
|
1979-10-18 |
1981-04-30 |
Univ Illinois |
Hydrolytic enzyme-activatible pro-drugs
|
|
US4419446A
(en)
|
1980-12-31 |
1983-12-06 |
The United States Of America As Represented By The Department Of Health And Human Services |
Recombinant DNA process utilizing a papilloma virus DNA as a vector
|
|
US4485045A
(en)
|
1981-07-06 |
1984-11-27 |
Research Corporation |
Synthetic phosphatidyl cholines useful in forming liposomes
|
|
NZ201705A
(en)
|
1981-08-31 |
1986-03-14 |
Genentech Inc |
Recombinant dna method for production of hepatitis b surface antigen in yeast
|
|
US4640835A
(en)
|
1981-10-30 |
1987-02-03 |
Nippon Chemiphar Company, Ltd. |
Plasminogen activator derivatives
|
|
US4741900A
(en)
|
1982-11-16 |
1988-05-03 |
Cytogen Corporation |
Antibody-metal ion complexes
|
|
US4601978A
(en)
|
1982-11-24 |
1986-07-22 |
The Regents Of The University Of California |
Mammalian metallothionein promoter system
|
|
US4560655A
(en)
|
1982-12-16 |
1985-12-24 |
Immunex Corporation |
Serum-free cell culture medium and process for making same
|
|
US4657866A
(en)
|
1982-12-21 |
1987-04-14 |
Sudhir Kumar |
Serum-free, synthetic, completely chemically defined tissue culture media
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
DD266710A3
(de)
|
1983-06-06 |
1989-04-12 |
Ve Forschungszentrum Biotechnologie |
Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase
|
|
US4544545A
(en)
|
1983-06-20 |
1985-10-01 |
Trustees University Of Massachusetts |
Liposomes containing modified cholesterol for organ targeting
|
|
US4767704A
(en)
|
1983-10-07 |
1988-08-30 |
Columbia University In The City Of New York |
Protein-free culture medium
|
|
US4496689A
(en)
|
1983-12-27 |
1985-01-29 |
Miles Laboratories, Inc. |
Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
|
|
US4965199A
(en)
|
1984-04-20 |
1990-10-23 |
Genentech, Inc. |
Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
|
|
US4879231A
(en)
|
1984-10-30 |
1989-11-07 |
Phillips Petroleum Company |
Transformation of yeasts of the genus pichia
|
|
US4737456A
(en)
|
1985-05-09 |
1988-04-12 |
Syntex (U.S.A.) Inc. |
Reducing interference in ligand-receptor binding assays
|
|
EP0206448B1
(en)
|
1985-06-19 |
1990-11-14 |
Ajinomoto Co., Inc. |
Hemoglobin combined with a poly(alkylene oxide)
|
|
GB8516415D0
(en)
|
1985-06-28 |
1985-07-31 |
Celltech Ltd |
Culture of animal cells
|
|
US4927762A
(en)
|
1986-04-01 |
1990-05-22 |
Cell Enterprises, Inc. |
Cell culture medium with antioxidant
|
|
GB8610600D0
(en)
|
1986-04-30 |
1986-06-04 |
Novo Industri As |
Transformation of trichoderma
|
|
US4791192A
(en)
|
1986-06-26 |
1988-12-13 |
Takeda Chemical Industries, Ltd. |
Chemically modified protein with polyethyleneglycol
|
|
GB8705477D0
(en)
|
1987-03-09 |
1987-04-15 |
Carlton Med Prod |
Drug delivery systems
|
|
US4975278A
(en)
|
1988-02-26 |
1990-12-04 |
Bristol-Myers Company |
Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells
|
|
WO1990003430A1
(en)
|
1988-09-23 |
1990-04-05 |
Cetus Corporation |
Cell culture medium for enhanced cell growth, culture longevity and product expression
|
|
FR2646437B1
(fr)
|
1989-04-28 |
1991-08-30 |
Transgene Sa |
Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant
|
|
EP0402226A1
(en)
|
1989-06-06 |
1990-12-12 |
Institut National De La Recherche Agronomique |
Transformation vectors for yeast yarrowia
|
|
US5013556A
(en)
|
1989-10-20 |
1991-05-07 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
US5122469A
(en)
|
1990-10-03 |
1992-06-16 |
Genentech, Inc. |
Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
|
|
WO1994004679A1
(en)
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
|
EP0590058B1
(en)
|
1991-06-14 |
2003-11-26 |
Genentech, Inc. |
HUMANIZED Heregulin ANTIBODy
|
|
CA2140933A1
(en)
|
1992-08-21 |
1994-02-22 |
Paula M. Jardieu |
Method for treating an lfa-1 mediated disorder
|
|
ATE139900T1
(de)
|
1992-11-13 |
1996-07-15 |
Idec Pharma Corp |
Therapeutische verwendung von chimerischen und markierten antikörper gegen menschlichen b lymphozyt beschränkter differenzierung antigen für die behandlung von b-zell-lymphoma
|
|
JP2000510813A
(ja)
|
1995-02-06 |
2000-08-22 |
ジェネテイックス・インスティテュート・インコーポレイテッド |
Il−12用処方
|
|
US6096871A
(en)
|
1995-04-14 |
2000-08-01 |
Genentech, Inc. |
Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life
|
|
US6037454A
(en)
|
1996-11-27 |
2000-03-14 |
Genentech, Inc. |
Humanized anti-CD11a antibodies
|
|
US5888809A
(en)
|
1997-05-01 |
1999-03-30 |
Icos Corporation |
Hamster EF-1α transcriptional regulatory DNA
|
|
ZA986596B
(en)
|
1997-07-25 |
1999-02-08 |
Schering Corp |
Mammalian cytokine related reagents
|
|
US6060284A
(en)
|
1997-07-25 |
2000-05-09 |
Schering Corporation |
DNA encoding interleukin-B30
|
|
AU2661199A
(en)
|
1998-02-06 |
1999-08-23 |
Schering Corporation |
Mammalian receptor proteins; related reagents and methods
|
|
ATE474849T1
(de)
|
1998-04-14 |
2010-08-15 |
Chugai Pharmaceutical Co Ltd |
Neues cytokinartiges protein
|
|
US6367172B2
(en)
|
1999-07-02 |
2002-04-09 |
Bbc International Ltd. |
Flex sole
|
|
US7090847B1
(en)
|
1999-09-09 |
2006-08-15 |
Schering Corporation |
Mammalian cytokines; related reagents and methods
|
|
US7422743B2
(en)
|
2000-05-10 |
2008-09-09 |
Schering Corporation |
Mammalian receptor protein DCRS5;methods of treatment
|
|
US6756481B2
(en)
|
2000-05-10 |
2004-06-29 |
Schering Corporation |
IL-23 receptor binding compositions
|
|
JPWO2003034818A1
(ja)
|
2001-10-24 |
2005-02-10 |
中外製薬株式会社 |
Sgrf遺伝子改変非ヒト動物
|
|
US20030138417A1
(en)
|
2001-11-08 |
2003-07-24 |
Kaisheva Elizabet A. |
Stable liquid pharmaceutical formulation of IgG antibodies
|
|
NZ539271A
(en)
|
2002-10-30 |
2008-12-24 |
Genentech Inc |
Inhibition of the production of proinflammatory cytokine interleukin-17 (IL-17) by T cells, using an antagonist of interleukin-23 (IL-23)
|
|
AU2003303384A1
(en)
|
2002-12-23 |
2004-07-22 |
Schering Corporation |
Uses of mammalian cytokine; related reagents
|
|
US20040219150A1
(en)
|
2003-02-06 |
2004-11-04 |
Cua Daniel J. |
Uses of mammalian cytokine; related reagents
|
|
ATE440864T1
(de)
|
2003-03-10 |
2009-09-15 |
Schering Corp |
Verwendung von il-23-antagonisten; verwandte reagenzien
|
|
US7413894B2
(en)
|
2003-07-01 |
2008-08-19 |
University Of Virginia Patent Foundation |
TAG-1 and TAG-2 proteins and uses thereof
|
|
US8277810B2
(en)
|
2003-11-04 |
2012-10-02 |
Novartis Vaccines & Diagnostics, Inc. |
Antagonist anti-CD40 antibodies
|
|
PT1684805E
(pt)
|
2003-11-04 |
2010-10-26 |
Novartis Vaccines & Diagnostic |
Utilização de anticorpos monoclonais antagonistas anti-cd40 para o tratamento do mieloma múltiplo
|
|
AU2004287879C1
(en)
|
2003-11-04 |
2011-05-26 |
Novartis Vaccines And Diagnostics, Inc. |
Antagonist anti-CD40 monoclonal antibodies and methods for their use
|
|
US20050100965A1
(en)
|
2003-11-12 |
2005-05-12 |
Tariq Ghayur |
IL-18 binding proteins
|
|
CN1942201B
(zh)
|
2004-02-17 |
2012-06-20 |
先灵公司 |
调节il-23活性的方法;相关试剂
|
|
AU2005241020B2
(en)
|
2004-05-03 |
2008-07-10 |
Merck Sharp & Dohme Corp. |
Use of IL-17 expression to predict skin inflammation; methods of treatment
|
|
US20050287593A1
(en)
|
2004-05-03 |
2005-12-29 |
Schering Corporation |
Use of cytokine expression to predict skin inflammation; methods of treatment
|
|
EP1799700A4
(en)
|
2004-09-27 |
2009-02-11 |
Centocor Inc |
SRAGE MIMETIC BODIES, COMPOSITIONS, PROCESSES AND USES
|
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
|
EP1853707A2
(en)
|
2004-12-20 |
2007-11-14 |
Schering Corporation |
Uses of il-23 antagonists in the treatment of diabetes mellitus
|
|
CA2613818C
(en)
|
2005-06-30 |
2013-08-27 |
Centocor, Inc. |
Anti-il-23 antibodies, compositions, methods and uses
|
|
AU2006265898A1
(en)
|
2005-06-30 |
2007-01-11 |
Archemix Corp. |
Polynucleotides and polypeptides of the IL-12 family of cytokines
|
|
SI1937721T1
(sl)
|
2005-08-25 |
2010-11-30 |
Lilly Co Eli |
Anti il protitelesa
|
|
ME02705B
(me)
|
2005-08-31 |
2017-10-20 |
Merck Sharp & Dohme |
Inženjerisana anti-il-23 antitela
|
|
DE602006009834D1
(de)
|
2005-09-01 |
2009-11-26 |
Schering Corp |
Verwendung von il-23 und il-17-antagonisten zur behandlung von autoimmuner entzündlicher augenerkrankung
|
|
CN101389769A
(zh)
|
2005-12-28 |
2009-03-18 |
森托科尔公司 |
用于评价和治疗银屑病及相关疾病的标记与方法
|
|
SI3219328T1
(sl)
|
2005-12-29 |
2020-10-30 |
Janssen Biotech, Inc. |
Človeška protitelesa proti-IL-23, sestavki, postopki in uporabe
|
|
US7910703B2
(en)
|
2006-03-10 |
2011-03-22 |
Zymogenetics, Inc. |
Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use
|
|
US20080311043A1
(en)
|
2006-06-08 |
2008-12-18 |
Hoffman Rebecca S |
Uses and compositions for treatment of psoriatic arthritis
|
|
JP2009540018A
(ja)
|
2006-06-13 |
2009-11-19 |
ザイモジェネティクス, インコーポレイテッド |
Il−17およびil−23アンタゴニストならびにその使用方法
|
|
CN101472611A
(zh)
|
2006-06-19 |
2009-07-01 |
惠氏公司 |
调节il-22和il-17的方法
|
|
JP5419709B2
(ja)
|
2007-01-09 |
2014-02-19 |
ワイス・エルエルシー |
抗il−13抗体製剤およびその使用
|
|
TWI426918B
(zh)
|
2007-02-12 |
2014-02-21 |
Merck Sharp & Dohme |
Il-23拮抗劑於治療感染之用途
|
|
US20080200591A1
(en)
|
2007-02-15 |
2008-08-21 |
Isao Noda |
Melt Processable Reactive Pellets Capable of Forming Ester Condensates and Process for Forming Melt Processable Reactive Pellets
|
|
AU2008216090A1
(en)
|
2007-02-16 |
2008-08-21 |
Wyeth |
Protein formulations containing sorbitol
|
|
HUE042172T2
(hu)
|
2007-02-23 |
2019-06-28 |
Merck Sharp & Dohme |
Genetikailag elõállított anti-il-23P19 antitestek
|
|
CN103396489A
(zh)
|
2007-02-23 |
2013-11-20 |
默沙东公司 |
工程改造的抗IL-23p19抗体
|
|
MX2009009167A
(es)
|
2007-02-28 |
2009-09-04 |
Schering Corp |
Terapia de combinacion para el tratamiento de trastornos inmunes.
|
|
DK2197903T3
(en)
|
2007-09-04 |
2015-01-05 |
Us Gov Health & Human Serv |
Deletions in Domain II from Pseudomonas exotoxin A that reduce non-specific TOXICITY
|
|
AR068723A1
(es)
|
2007-10-05 |
2009-12-02 |
Glaxo Group Ltd |
Proteina que se une a antigenos que se une a il-23 humana y sus usos
|
|
WO2009053493A1
(en)
|
2007-10-26 |
2009-04-30 |
Galderma Research & Development |
Non-invasive method to perform skin inflammatory disease pharmaco-genomic studies and diagnosis method thereof
|
|
CA2607771A1
(en)
|
2007-11-01 |
2009-05-01 |
Her Majesty The Queen In Right Of Canada As Represented By The Minister Of National Defence |
Humanized anti-venezuelan equine encephalitis virus recombinant antibody
|
|
US8420081B2
(en)
|
2007-11-30 |
2013-04-16 |
Abbvie, Inc. |
Antibody formulations and methods of making same
|
|
WO2009082624A2
(en)
|
2007-12-10 |
2009-07-02 |
Zymogenetics, Inc. |
Antagonists of il-17a, il-17f, and il-23 and methods of using the same
|
|
MX2011001409A
(es)
|
2008-08-14 |
2011-03-29 |
Cephalon Australia Pty Ltd |
Anticuerpos anti-il-12/il-23.
|
|
WO2010027766A1
(en)
|
2008-08-27 |
2010-03-11 |
Schering Corporation |
Lyophilized formulatons of engineered anti-il-23p19 antibodies
|
|
EP2352762A1
(en)
|
2008-11-03 |
2011-08-10 |
Schering Corporation |
Inflammatory bowel disease biomarkers and related methods of treatment
|
|
US8420089B2
(en)
|
2008-11-25 |
2013-04-16 |
Alderbio Holdings Llc |
Antagonists of IL-6 to raise albumin and/or lower CRP
|
|
MX2011005672A
(es)
|
2008-11-28 |
2011-06-20 |
Abbott Lab |
Composiciones de anticuerpo estables y metodos para estabilizar a las mismas.
|
|
WO2010115786A1
(en)
|
2009-04-01 |
2010-10-14 |
Glaxo Group Limited |
Anti-il-23 immunoglobulins
|
|
EP2414546A4
(en)
|
2009-04-02 |
2013-03-13 |
Univ Johns Hopkins |
COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF INFLAMMATORY DISEASE AND COLON CARCINOMA
|
|
US20120269765A1
(en)
|
2009-07-24 |
2012-10-25 |
Garcia K Christopher |
Cytokine compositions and methods of use thereof
|
|
JO3244B1
(ar)
|
2009-10-26 |
2018-03-08 |
Amgen Inc |
بروتينات ربط مستضادات il – 23 البشرية
|
|
EP2504032A4
(en)
|
2009-11-24 |
2013-06-19 |
Alderbio Holdings Llc |
IL-6 ANTAGONISTS FOR PREVENTING OR TREATING THROMBOSIS
|
|
WO2011069000A2
(en)
|
2009-12-02 |
2011-06-09 |
Spartek Medical, Inc. |
Low profile spinal prosthesis incorporating a bone anchor having a deflectable post and a compound spinal rod
|
|
GB201013975D0
(en)
|
2010-08-20 |
2010-10-06 |
Imp Innovations Ltd |
Method of treating desease
|
|
PE20130041A1
(es)
|
2010-02-18 |
2013-01-28 |
Bristol Myers Squibb Co |
Proteinas de dominio de andamiaje de fibronectina que se unen a interleucina 23 (il-23)
|
|
SI3409289T1
(sl)
|
2010-02-26 |
2020-12-31 |
Novo Nordisk A/S |
Stabilni sestavki, ki vsebujejo protitelo
|
|
SG184355A1
(en)
|
2010-03-01 |
2012-11-29 |
Progenics Pharm Inc |
Concentrated protein formulations and uses thereof
|
|
JP2013531499A
(ja)
|
2010-06-15 |
2013-08-08 |
セルジーン コーポレイション |
乾癬の治療のためのバイオマーカー
|
|
US20110311527A1
(en)
|
2010-06-16 |
2011-12-22 |
Allergan, Inc. |
IL23p19 ANTIBODY INHIBITOR FOR TREATING OCULAR AND OTHER CONDITIONS
|
|
JP5972871B2
(ja)
|
2010-07-20 |
2016-08-17 |
テバ・ファーマシューティカルズ・オーストラリア・ピーティワイ・リミテッド |
抗il−23ヘテロ二量体特異的抗体
|
|
CN103261222B
(zh)
|
2010-09-10 |
2017-07-28 |
医疗免疫有限公司 |
抗体衍生物
|
|
KR102049223B1
(ko)
|
2010-11-04 |
2019-11-28 |
베링거 인겔하임 인터내셔날 게엠베하 |
항-il-23 항체
|
|
GB201100282D0
(en)
|
2011-01-07 |
2011-02-23 |
Ucb Pharma Sa |
Biological methods
|
|
TW201309330A
(zh)
|
2011-01-28 |
2013-03-01 |
Abbott Lab |
包含糖基化抗體之組合物及其用途
|
|
WO2012104402A1
(en)
|
2011-02-04 |
2012-08-09 |
Ab Science |
Treatment of severe persitent asthma with masitinib
|
|
CN109206516A
(zh)
|
2012-05-03 |
2019-01-15 |
勃林格殷格翰国际有限公司 |
抗IL-23p19抗体
|
|
EP2863951A1
(en)
|
2012-06-12 |
2015-04-29 |
Boehringer Ingelheim International GmbH |
Pharmaceutical formulation for a therapeutic antibody
|
|
US9803010B2
(en)
*
|
2012-06-27 |
2017-10-31 |
Merck Sharp & Dohme Corp. |
Crystalline anti-human IL-23p19 antibodies
|
|
EP3689369A1
(en)
*
|
2013-03-15 |
2020-08-05 |
Amgen, Inc |
Methods for treating psoriasis using an anti-il-23 antibody
|
|
US20160031983A1
(en)
|
2013-03-15 |
2016-02-04 |
Amgen Inc. |
Methods for treating crohn's disease using an anti-il23 antibody
|
|
KR20140119396A
(ko)
|
2013-03-29 |
2014-10-10 |
삼성전자주식회사 |
단백질 약물의 액상 제형
|
|
EP3172339A1
(en)
|
2014-07-24 |
2017-05-31 |
Boehringer Ingelheim International GmbH |
Biomarkers useful in the treatment of il-23a related diseases
|
|
CA2959629C
(en)
|
2014-09-03 |
2023-10-31 |
Boehringer Ingelheim International Gmbh |
Compound targeting il-23a and tnf-alpha and uses thereof
|
|
KR20170120616A
(ko)
|
2015-02-04 |
2017-10-31 |
베링거 인겔하임 인터내셔날 게엠베하 |
염증성 질환의 치료 방법
|
|
MX2017013156A
(es)
|
2015-04-14 |
2018-02-21 |
Boehringer Ingelheim Int |
Metodos para tratar enfermedades.
|
|
PE20180774A1
(es)
|
2015-07-23 |
2018-05-07 |
Boehringer Ingelheim Int |
Compuesto que se dirige a il-23a y al factor de activacion de linfocitos b (baff) y usos de estos
|
|
TWI811716B
(zh)
|
2015-09-18 |
2023-08-11 |
德商百靈佳殷格翰國際股份有限公司 |
治療發炎性疾病之方法
|
|
AU2017250583A1
(en)
|
2016-04-15 |
2018-08-16 |
Boehringer Ingelheim International Gmbh |
Methods of treating inflammatory diseases
|
|
GB201612317D0
(en)
|
2016-07-15 |
2016-08-31 |
Philogen Spa |
Antibody compositions
|
|
CA3031860A1
(en)
|
2016-08-17 |
2018-02-22 |
Boehringer Ingelheim International Gmbh |
Process for the preparation of highly concentrated liquid formulations containing biomolecules
|
|
WO2018071504A2
(en)
|
2016-10-14 |
2018-04-19 |
Boehringer Ingelheim International Gmbh |
Methods of treating diseases
|
|
WO2019246271A1
(en)
|
2018-06-20 |
2019-12-26 |
Progenity, Inc. |
Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor
|
|
JP7090014B2
(ja)
*
|
2018-11-07 |
2022-06-23 |
株式会社ミツバ |
ロータ、モータ、ブラシレスワイパーモータ及びロータの製造方法
|
|
TW202535466A
(zh)
|
2019-09-09 |
2025-09-16 |
德商百靈佳殷格翰國際股份有限公司 |
抗-il-23p19抗體調配物
|
|
JP2025535439A
(ja)
|
2022-10-21 |
2025-10-24 |
チョン クン ダン ファーマシューティカル コーポレーション |
安定した抗体組成物
|