CL2017002241A1 - Método de tratamiento de cáncer asociado con una mutación de ras - Google Patents

Método de tratamiento de cáncer asociado con una mutación de ras

Info

Publication number
CL2017002241A1
CL2017002241A1 CL2017002241A CL2017002241A CL2017002241A1 CL 2017002241 A1 CL2017002241 A1 CL 2017002241A1 CL 2017002241 A CL2017002241 A CL 2017002241A CL 2017002241 A CL2017002241 A CL 2017002241A CL 2017002241 A1 CL2017002241 A1 CL 2017002241A1
Authority
CL
Chile
Prior art keywords
cancer treatment
ras mutation
treatment associated
cancer
ras
Prior art date
Application number
CL2017002241A
Other languages
English (en)
Inventor
Lan Huang
Original Assignee
Beyondspring Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56878960&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2017002241(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Beyondspring Pharmaceuticals Inc filed Critical Beyondspring Pharmaceuticals Inc
Publication of CL2017002241A1 publication Critical patent/CL2017002241A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

<p>Se describen en la presente métodos para tratar un cáncer caracterizado por expresar una forma mutante de una proteína RAS. Algunas modalidades se refieren al tratamiento de cáncer mediante la administración de Plinabulina a un sujeto que lo necesite.</p>
CL2017002241A 2015-03-06 2017-09-04 Método de tratamiento de cáncer asociado con una mutación de ras CL2017002241A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562129654P 2015-03-06 2015-03-06
US201562249788P 2015-11-02 2015-11-02

Publications (1)

Publication Number Publication Date
CL2017002241A1 true CL2017002241A1 (es) 2018-04-02

Family

ID=56878960

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2017002241A CL2017002241A1 (es) 2015-03-06 2017-09-04 Método de tratamiento de cáncer asociado con una mutación de ras

Country Status (16)

Country Link
US (4) US10238650B2 (es)
EP (1) EP3265090A4 (es)
JP (1) JP6769982B2 (es)
KR (1) KR102626155B1 (es)
CN (1) CN107530341B (es)
AU (2) AU2016229294B2 (es)
BR (1) BR112017018954A2 (es)
CA (1) CA2978567A1 (es)
CL (1) CL2017002241A1 (es)
HK (1) HK1249052A1 (es)
IL (1) IL254256A0 (es)
MX (1) MX383691B (es)
MY (1) MY190034A (es)
RU (1) RU2736045C2 (es)
SG (2) SG10202008673WA (es)
WO (1) WO2016144635A1 (es)

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WO2024088275A1 (zh) * 2022-10-25 2024-05-02 中国科学院上海药物研究所 一种萘酰胺化合物治疗耐药性肿瘤的用途
CN117919235A (zh) * 2022-10-25 2024-04-26 上海润石医药科技有限公司 一种萘酰胺化合物治疗kras突变相关疾病的用途
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