CL2019000392A1 - Métodos para detectar aav. - Google Patents

Métodos para detectar aav.

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Publication number
CL2019000392A1
CL2019000392A1 CL2019000392A CL2019000392A CL2019000392A1 CL 2019000392 A1 CL2019000392 A1 CL 2019000392A1 CL 2019000392 A CL2019000392 A CL 2019000392A CL 2019000392 A CL2019000392 A CL 2019000392A CL 2019000392 A1 CL2019000392 A1 CL 2019000392A1
Authority
CL
Chile
Prior art keywords
methods
aav
particles
heterogeneity
particle
Prior art date
Application number
CL2019000392A
Other languages
English (en)
Inventor
Xiaoying Jin
Catherine R O'riordan
Lin Liu
Kate Zhang
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=59762045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2019000392(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of CL2019000392A1 publication Critical patent/CL2019000392A1/es

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    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
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    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
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    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
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    • G01N30/72—Mass spectrometers
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    • G01N30/02—Column chromatography
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
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    • C12N2750/14011—Parvoviridae
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    • C12N2750/00011—Details
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151—Methods of production or purification of viral material
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    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
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    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses
    • G01N2333/075—Adenoviridae

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Abstract

EN LA PRESENTE MEMORIA SE PROPORCIONAN MÉTODOS PARA DETERMINAR EL SEROTIPO DE UNA PARTÍCULA DE VIRUS Y/O PARA DETERMINAR LA HETEROGENEIDAD DE UNA PARTÍCULA DE VIRUS (P. EJ., UNA PARTÍCULA DE AAV). EN OTRAS REALIZACIONES, LA INVENCIÓN PROPORCIONA MÉTODOS PARA DETERMINAR LA HETEROGENEIDAD DE PARTÍCULAS DE AAV. EN ALGUNOS ASPECTOS, LA INVENCIÓN PROPORCIONA PARTÍCULAS VIRALES (P. EJ., PARTÍCULAS DE AAVR) CON ESTABILIDAD MEJORADA Y/O EFICIENCIA DE LA TRANSDUCCIÓN MEJORADA MEDIANTE EL INCREMENTO DE LA ACETILACIÓN Y/O DESAMIDACIÓN DE LAS PROTEÍNAS DE LA CÁPSIDE.
CL2019000392A 2016-08-15 2019-02-13 Métodos para detectar aav. CL2019000392A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662375314P 2016-08-15 2016-08-15

Publications (1)

Publication Number Publication Date
CL2019000392A1 true CL2019000392A1 (es) 2019-05-10

Family

ID=59762045

Family Applications (2)

Application Number Title Priority Date Filing Date
CL2019000392A CL2019000392A1 (es) 2016-08-15 2019-02-13 Métodos para detectar aav.
CL2019002912A CL2019002912A1 (es) 2016-08-15 2019-10-14 Métodos para detectar aav. (divisional solicitud 201900392).

Family Applications After (1)

Application Number Title Priority Date Filing Date
CL2019002912A CL2019002912A1 (es) 2016-08-15 2019-10-14 Métodos para detectar aav. (divisional solicitud 201900392).

Country Status (23)

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US (5) US11698377B2 (es)
EP (2) EP3851449A1 (es)
JP (3) JP7021191B2 (es)
KR (5) KR102538037B1 (es)
CN (2) CN110168080B (es)
AU (2) AU2017312951B2 (es)
CA (1) CA3033856A1 (es)
CL (2) CL2019000392A1 (es)
CR (1) CR20190127A (es)
CY (1) CY1124364T1 (es)
DK (1) DK3497207T3 (es)
ES (1) ES2863674T3 (es)
HU (1) HUE053747T2 (es)
IL (3) IL264819B2 (es)
MA (1) MA55748A (es)
MX (2) MX2019001938A (es)
NZ (3) NZ791267A (es)
PH (1) PH12019500316A1 (es)
SG (2) SG10201913002QA (es)
TN (1) TN2019000047A1 (es)
TW (2) TW202309068A (es)
WO (1) WO2018035059A1 (es)
ZA (2) ZA201900945B (es)

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CA3033856A1 (en) 2018-02-22
US12123880B2 (en) 2024-10-22
US20210041451A1 (en) 2021-02-11
TW202309068A (zh) 2023-03-01
KR20260036296A (ko) 2026-03-16
NZ791263A (en) 2025-11-28
CL2019002912A1 (es) 2020-03-06
HUE053747T2 (hu) 2021-07-28
KR102738219B1 (ko) 2024-12-05
KR20190039253A (ko) 2019-04-10
US20240044910A1 (en) 2024-02-08
KR102922101B1 (ko) 2026-02-03
US12298313B1 (en) 2025-05-13
IL264819B1 (en) 2024-06-01
IL323969A (en) 2025-12-01
KR20230078834A (ko) 2023-06-02
EP3497207B1 (en) 2021-01-06
CN118688363A (zh) 2024-09-24
JP2022064980A (ja) 2022-04-26
WO2018035059A1 (en) 2018-02-22
CY1124364T1 (el) 2022-07-22
RU2019107207A3 (es) 2021-04-29
MX2019001938A (es) 2019-07-04
IL312792B1 (en) 2025-11-01
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BR112019002934A2 (pt) 2019-05-14
RU2019107207A (ru) 2020-09-15
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AU2024200349A1 (en) 2024-02-08
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