CN1056881C - 编码杀虫剂蛋白的基因、用该基因转化的禾本科植物及其制备方 - Google Patents

编码杀虫剂蛋白的基因、用该基因转化的禾本科植物及其制备方 Download PDF

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Publication number
CN1056881C
CN1056881C CN92115178A CN92115178A CN1056881C CN 1056881 C CN1056881 C CN 1056881C CN 92115178 A CN92115178 A CN 92115178A CN 92115178 A CN92115178 A CN 92115178A CN 1056881 C CN1056881 C CN 1056881C
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gene
plant
ser
dna
codon
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CN1073717A (zh
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藤本英也
伊藤纪美子
山本干博
岛本功
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Mitsubishi Corp
Mitsubishi Chemical Corp
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Mitsubishi Corp
Mitsubishi Chemical Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H6/00—Angiosperms, i.e. flowering plants, characterised by their botanic taxonomy
    • A01H6/46—Gramineae or Poaceae, e.g. ryegrass, rice, wheat or maize

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Physiology (AREA)
  • Botany (AREA)
  • Developmental Biology & Embryology (AREA)
  • Environmental Sciences (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN92115178A 1991-11-29 1992-11-28 编码杀虫剂蛋白的基因、用该基因转化的禾本科植物及其制备方 Expired - Fee Related CN1056881C (zh)

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JP340059/1991 1991-11-29
JP340059/91 1991-11-29
JP34005991 1991-11-29

Publications (2)

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CN1073717A CN1073717A (zh) 1993-06-30
CN1056881C true CN1056881C (zh) 2000-09-27

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CN92115178A Expired - Fee Related CN1056881C (zh) 1991-11-29 1992-11-28 编码杀虫剂蛋白的基因、用该基因转化的禾本科植物及其制备方

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US (1) US5436391A (2)
KR (1) KR100217517B1 (2)
CN (1) CN1056881C (2)
TW (1) TW261517B (2)

Families Citing this family (374)

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Publication number Priority date Publication date Assignee Title
US6403865B1 (en) 1990-08-24 2002-06-11 Syngenta Investment Corp. Method of producing transgenic maize using direct transformation of commercially important genotypes
UA48104C2 (uk) * 1991-10-04 2002-08-15 Новартіс Аг Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника
EP0793717B1 (en) * 1994-10-24 2005-01-26 The Texas A & M University System Oral immunization with transgenic plants
AU724041B2 (en) * 1995-10-12 2000-09-07 Cornell Research Foundation Inc. Production of water stress or salt stress tolerant transgenic cereal plants
IL132580A0 (en) 1997-08-12 2001-03-19 Univ North Carolina State Genetically engineered duckweed
US6121521A (en) * 1998-04-01 2000-09-19 Novartis Ag Chimeric insecticidal protein and DNA coding therefor
US6399857B1 (en) 1999-09-22 2002-06-04 Paradigm Genetics, Inc. Modified nucleotide sequence encoding a LexA DNA binding domain optimized for arabidopsis species
WO2002010190A2 (en) * 2000-07-29 2002-02-07 Genaissance Pharmaceuticals, Inc. Haplotypes of the il12b gene
WO2002010398A2 (en) 2000-07-31 2002-02-07 Hahn Frederick M Manipulation of genes of the mevalonate and isoprenoid pathways to create novel traits in transgenic organisms
EP1349946B1 (en) 2000-08-25 2011-01-26 BASF Plant Science GmbH Plant polynucleotides encoding prenyl proteases
US6875907B2 (en) 2000-09-13 2005-04-05 Pioneer Hi-Bred International, Inc. Antimicrobial peptides and methods of use
BR0210593A (pt) 2001-06-22 2007-01-02 Pioneer Hi Bred Int polinucleotìdeos de defensina e métodos de uso
WO2003020914A2 (en) 2001-09-05 2003-03-13 Basf Plant Science Gmbh Protein phosphatase stress-related polypeptides and methods of use in plants
CA2465951A1 (en) 2001-11-09 2003-05-15 Basf Plant Science Gmbh Transcription factor stress-related polypeptides and methods of use in plants
CA2492167C (en) 2002-07-10 2015-06-16 The Department Of Agriculture, Western Australia Wheat plants having increased resistance to imidazolinone herbicides
US20040268441A1 (en) 2002-07-19 2004-12-30 University Of South Carolina Compositions and methods for the modulation of gene expression in plants
US7460252B2 (en) * 2003-01-13 2008-12-02 Axiohm Transaction Solutions, Inc. Graphical printing system and method using text triggers
CA2516349C (en) 2003-02-20 2014-05-13 Athenix Corporation Delta-endotoxin genes and methods for their use
EP2194134A3 (en) 2003-04-15 2010-10-06 BASF Plant Science GmbH Nucleic acid sequences from yeast encoding proteins associated with abiotic stress response and transformed plant cells and plants with increased tolerance to environmental stress
US9382526B2 (en) 2003-05-28 2016-07-05 Basf Aktiengesellschaft Wheat plants having increased tolerance to imidazolinone herbicides
BRPI0413917B1 (pt) 2003-08-29 2018-09-25 Instituto Nacional De Tech Agropecuaria ácido nucleico ahas de arroz mutagenizado não transgênico, polipeptídeo ahas isolado, e, método de controle de ervas daninhas dentro da vizinhança de uma planta de arroz
US20060260004A1 (en) * 2004-04-01 2006-11-16 Yiwen Fang Par-related protein promoters
CA2571585C (en) 2004-06-30 2011-11-08 Pioneer Hi-Bred International, Inc. Methods of protecting plants from pathogenic fungi
EP1763536B1 (en) 2004-07-02 2010-09-08 Pioneer-Hi-Bred International, Inc. Antifungal polypeptides
CN101495507B (zh) 2004-09-24 2013-07-17 巴斯福植物科学有限公司 编码与非生物性胁迫反应相关的蛋白质的核酸序列和具有增加的环境胁迫抗性的植物细胞和植物
EP1831376A1 (en) 2004-12-28 2007-09-12 Pioneer Hi-Bred International, Inc. Improved grain quality through altered expression of seed proteins
EP3581024A1 (en) 2005-03-02 2019-12-18 Instituto Nacional de Tecnologia Agropecuaria Herbicide-resistant rice plants, polynucleotides encoding herbicide-resistant acetohydroxyacid synthase large subunit proteins, and methods of use
ATE548378T1 (de) 2005-04-01 2012-03-15 Athenix Corp Axmi-036 ein delta-endotoxin-gen und verfahren zur dessen verwendung
EP1871875A2 (en) 2005-04-08 2008-01-02 Athenix Corporation Identification of a new class of epsp synthases
US7880055B2 (en) 2005-06-17 2011-02-01 Basf Plant Science Gmbh Lecitin-like protein kinase stress-related polypeptides and methods of use in plants
US7598367B2 (en) * 2005-06-30 2009-10-06 Ceres, Inc. Early light-induced protein promoters
CN101287836B (zh) 2005-07-01 2013-02-20 巴斯福股份公司 抗除草剂的向日葵植物、编码抗除草剂的乙酰羟酸合酶大亚基蛋白的多核苷酸和使用方法
EP3222729A3 (en) 2005-07-18 2017-11-08 BASF Plant Science GmbH Increase in root length in arabidopsis plants over-expressing the arabidopsis shmt4 (shm4) gene (at4g13930)
CN101228277B (zh) 2005-07-18 2013-11-27 巴斯福植物科学有限公司 过表达accdp基因的植物中的产量增加
CN101365794A (zh) 2005-08-12 2009-02-11 巴斯福植物科学有限公司 编码与非生物性胁迫应答相关的蛋白质的核酸序列和具有增加的环境胁迫耐受性的植物细胞及植物
EP2112223A3 (en) 2005-11-10 2010-01-27 Pioneer Hi-Bred International Inc. DOF (DNA binding with one finger) sequences and method of use
US20070199096A1 (en) 2005-11-14 2007-08-23 E.I. Du Pont De Nemours And Company Compositions and Methods for Altering Alpha- and Beta-Tocotrienol Content
AR057205A1 (es) 2005-12-01 2007-11-21 Athenix Corp Genes grg23 y grg51 que confieren resistencia a herbicidas
US20080313769A9 (en) 2006-01-12 2008-12-18 Athenix Corporation EPSP synthase domains conferring glyphosate resistance
US7622573B2 (en) 2006-01-17 2009-11-24 Biolex, Inc. Expression control elements from the lemnaceae family
US8237014B2 (en) * 2006-02-27 2012-08-07 Edenspace Systems Corporation Energy crops for improved biofuel feedstocks
AU2007223364B2 (en) 2006-03-02 2014-02-13 Athenix Corporation Methods and compositions for improved enzyme activity in transgenic plant
EP2333078A3 (en) 2006-03-24 2012-01-04 BASF Plant Science GmbH Proteins associated with abiotic stress response and homologs
EP2251349A1 (en) 2006-04-19 2010-11-17 Pioneer Hi-Bred International, Inc. Isolated polynucleotide molecules corresponding to mutant and wild-type alleles of the maize D9 gene and methods of use
ATE497539T1 (de) 2006-05-16 2011-02-15 Pioneer Hi Bred Int Antimykotische polypeptide
WO2007137114A2 (en) 2006-05-17 2007-11-29 Pioneer Hi-Bred International, Inc. Artificial plant minichromosomes
EP2455391A3 (en) 2006-06-15 2012-08-22 Athenix Corporation A family of pesticidal proteins and methods for their use
US7994390B2 (en) 2006-09-29 2011-08-09 The Chinese University Of Hong Kong Use of GmRD22-like genes to protect against abiotic stress
US20080104726A1 (en) * 2006-10-05 2008-05-01 Ceres, Inc. Fruit regulatory regions
US20100162433A1 (en) 2006-10-27 2010-06-24 Mclaren James Plants with improved nitrogen utilization and stress tolerance
US7888069B2 (en) * 2006-12-22 2011-02-15 Dow Agrosciences Llc Plant-made west nile virus (WNV) vaccines, vectors and plant codon optimized sequences
WO2008118394A1 (en) * 2007-03-23 2008-10-02 New York University Methods of affecting nitrogen assimilation in plants
CN101652480A (zh) 2007-03-23 2010-02-17 巴斯福植物科学有限公司 具有提高的胁迫耐受性和产量的转基因植物
NZ597327A (en) 2007-04-04 2014-02-28 Basf Se Herbicide-resistant brassica plants and methods of use
CA2682349C (en) 2007-04-04 2017-08-22 Basf Plant Science Gmbh Ahas mutants
US20100154076A1 (en) 2007-05-25 2010-06-17 Cropdesign N.V. Yield Enhancement In Plants By Modulation of Maize Alfins
CA2687320A1 (en) 2007-05-29 2008-12-04 Basf Plant Science Gmbh Transgenic plants with increased stress tolerance and yield
EP2520656A3 (en) 2007-07-13 2013-05-01 BASF Plant Science GmbH Transgenic plants with increased stress tolerance and yield
CN101809155A (zh) 2007-08-02 2010-08-18 巴斯夫植物科学有限公司 具有增加的胁迫耐受性和产量的转基因植物
AR068847A1 (es) 2007-10-10 2009-12-09 Athenix Corp Genes sinteticos que codifican cry1ac
EA201070371A1 (ru) 2007-10-16 2011-02-28 Атеникс Корпорейшн Axmi-066 и axmi-076: дельта-эндотоксиновые белки и способы их применения
DE112008003224T5 (de) 2007-11-27 2010-12-23 Basf Plant Science Gmbh Transgene Pflanzen mit erhöhter Stresstoleranz und erhöhtem Ertrag
CN105368764B (zh) 2007-12-13 2019-03-12 丹尼斯科美国公司 用于生产异戊二烯的组合物和方法
WO2009146015A2 (en) * 2008-03-31 2009-12-03 Ceres, Inc. Promoter, promoter control elements, and combinations, and uses thereof
WO2009132220A2 (en) * 2008-04-23 2009-10-29 Danisco Us Inc. Isoprene synthase variants for improved microbial production of isoprene
MX351227B (es) 2008-06-25 2017-09-14 Athenix Corp Genes de toxinas y métodos para su uso.
WO2010003065A2 (en) 2008-07-02 2010-01-07 Athenix Corporation Axmi-115, axmi-113, axmi-005, axmi-163 and axmi-184: insecticidal proteins and methods for their use
RS54868B1 (sr) 2008-07-31 2016-10-31 Anglo Netherlands Grain Bv Biljke suncokreta rezistentne na herbicide
US20110145948A1 (en) 2008-08-20 2011-06-16 BASG Plant Science GmbH Transgenic Plants Comprising as Transgene a Phosphatidate Cytidylyltransferase
EP2334795B1 (en) 2008-09-08 2014-04-30 Athenix Corporation Compositions and methods for expression of a heterologous nucleotide sequence in plants
MX301701B (es) 2008-09-23 2012-07-26 Basf Plant Science Gmbh Plantas transgenicas con rendimiento incrementado.
EP2733212B1 (en) 2008-09-26 2018-09-05 BASF Agrochemical Products, B.V. Herbicide-resistant ahas-mutants and methods of use
RU2559527C2 (ru) 2008-11-28 2015-08-10 Мериал Лимитед Рекомбинантная вакцина от птичьего гриппа и её применение
CA2743707A1 (en) 2008-12-04 2010-06-10 Pioneer Hi-Bred International, Inc. Methods and compositions for enhanced yield by targeted expression of knotted1
BRPI0923334A2 (pt) 2008-12-15 2021-09-08 Athenix Corporation Gene que codifica toxinas de nematoide.
US8293533B2 (en) * 2008-12-19 2012-10-23 E.I. Du Pont De Nemours And Company Site-specific integration and stacking of transgenes in soybean via DNA recombinase mediated cassette exchange
CA2747812A1 (en) 2008-12-22 2010-07-01 Athenix Corporation Pesticidal genes from brevibacillus and methods for their use
CA2747826A1 (en) 2008-12-23 2010-07-01 Athenix Corporation Axmi-150 delta-endotoxin gene and methods for its use
CN101768213B (zh) 2008-12-30 2012-05-30 中国科学院遗传与发育生物学研究所 一种与植物分蘖数目相关的蛋白及其编码基因与应用
EP2206723A1 (en) 2009-01-12 2010-07-14 Bonas, Ulla Modular DNA-binding domains
US20110239315A1 (en) 2009-01-12 2011-09-29 Ulla Bonas Modular dna-binding domains and methods of use
WO2010086277A2 (en) 2009-01-28 2010-08-05 Basf Plant Science Company Gmbh Engineering nf-yb transcription factors for enhanced drought resistance and increased yield in transgenic plants
CA2750456A1 (en) 2009-01-28 2010-08-05 Basf Plant Science Company Gmbh Transgenic plants having altered nitrogen metabolism
US8299217B2 (en) 2009-02-05 2012-10-30 Athenix Corp. Variant AXMI-R1 delta endotoxin genes and methods for their use
AR075240A1 (es) 2009-02-06 2011-03-16 Syngenta Participations Ag Modificacion de enzima multidominio para la expresion en plantas
US20120058523A1 (en) 2009-02-17 2012-03-08 Edenspace Systems Corporation Tempering of cellulosic biomass
MY189620A (en) * 2009-02-20 2022-02-21 Malaysian Palm Oil Board A constitutive promoter from oil palm
CN101817879A (zh) 2009-02-26 2010-09-01 中国科学院遗传与发育生物学研究所 金属硫蛋白及其编码基因与应用
EP2401380B1 (en) 2009-02-27 2015-08-19 Athenix Corporation Pesticidal proteins and methods for their use
EP2403948A1 (en) 2009-03-06 2012-01-11 Athenix Corporation Methods and compositions for controlling plant pests
MX2011009496A (es) 2009-03-11 2011-10-14 Athenix Corp Axmi-001, axmi-002, axmi-030, axmi-035 y axmi-045: genes de toxina y metodos para su uso.
CN102361988A (zh) 2009-03-23 2012-02-22 巴斯夫植物科学有限公司 具有改变的氧化还原机制和提高的产量的转基因植物
AU2010238770A1 (en) 2009-04-23 2011-11-03 Danisco Us Inc. Three-dimensional structure of isoprene synthase and its use thereof for generating variants
MX2011011678A (es) 2009-05-04 2011-12-06 Pioneer Hi Bred Int Mejora de la produccion en plantas mediante la modulacion del factor de transcripcion ap2.
MY186558A (en) * 2009-05-13 2021-07-27 Malaysian Palm Oil Board A constitutive promoter from oil palm type 2
WO2010132214A1 (en) * 2009-05-15 2010-11-18 University Of Tennessee Research Foundation Environmental stress-inducible promoter and its application in crops
EP2435562A1 (en) 2009-05-26 2012-04-04 Biolex Therapeutics, Inc. Compositions and methods for production of aglycosylated plasminogen
US20120079627A1 (en) 2009-05-29 2012-03-29 Edenspace Systems Corporation Plant gene regulatory elements
CA2765034A1 (en) 2009-06-09 2010-12-23 Pioneer Hi-Bred International, Inc. Early endosperm promoter and methods of use
CN107129998A (zh) 2009-06-10 2017-09-05 淡马锡生命科学研究院有限公司 用于棉花中基因功能性分析的病毒诱导的基因沉默(vigs)
MX346215B (es) 2009-07-02 2017-03-10 Athenix Corp Gen plaguicida axmi-205 y metodos para su uso.
MX354219B (es) 2009-07-31 2018-02-19 Athenix Corp Familia de genes plaguicidas axmi-192 y metodos para su uso.
US8778672B2 (en) 2009-10-26 2014-07-15 Pioneer Hi Bred International Inc Somatic ovule specific promoter and methods of use
CN101818157B (zh) * 2009-12-02 2013-01-02 安徽省农业科学院水稻研究所 一种人工设计的Bt抗虫基因及其应用
CN103260643A (zh) 2009-12-28 2013-08-21 梅里亚有限公司 重组ndv抗原及其用途
AU2010339404B2 (en) 2009-12-30 2016-01-28 Pioneer Hi-Bred International, Inc. Methods and compositions for the introduction and regulated expression of genes in plants
US8704041B2 (en) 2009-12-30 2014-04-22 Pioneer Hi Bred International Inc Methods and compositions for targeted polynucleotide modification
BR112012018616A2 (pt) 2010-01-26 2017-01-10 Pioneer Hi Bred Int marcador de polinucleotídeo, polinucleotídeo isolado, polipeptídeo transportador abc isolado, planta, célula, semente, método para seleção de uma planta ou germoplasma de soja, método de introgressão de um alelo de resistência a herbicida em uma planta de soja, método para conferir tolerância ou tolerância melhorada a um ou mais herbicidas, método para controlar de modo seletivo plantas daninhas em um campo contendo uma cultura
AU2011218130B2 (en) 2010-02-18 2016-03-03 Athenix Corp. AXMI218, AXMI219, AXMI220, AXMI226, AXMI227, AXMI228, AXMI229, AXMI230, and AXMI231 delta-endotoxin genes and methods for their use
CA2790029C (en) 2010-02-18 2019-09-03 Athenix Corp. Axmi221z, axmi222z, axmi223z, axmi224z, and axmi225z delta-endotoxin genes and methods for their use
ES2617743T3 (es) 2010-03-12 2017-06-19 Merial, Inc. Vacunas recombinantes del virus de la lengua azul y sus utilizaciones
WO2011145015A1 (en) 2010-05-04 2011-11-24 Basf Se Plants having increased tolerance to herbicides
AR080745A1 (es) 2010-05-06 2012-05-02 Du Pont Gen y proteina acc (acido 1-aminociclopropano-1-carboxilico) sintasa 3 de maiz y sus usos
US9234208B1 (en) * 2010-05-10 2016-01-12 Dow Agrosciences Llc DIG-13 insecticidal cry toxins
FR2961375B1 (fr) 2010-06-16 2016-05-13 Inst De Rech Pour Le Dev (Ird) Surproduction d'acide jasmonique dans des plantes transgeniques
US20120122223A1 (en) 2010-08-03 2012-05-17 Cibus Us Llc Mutated protoporphyrinogen ix oxidase (ppx) genes
UA112969C2 (uk) 2010-08-03 2016-11-25 Сібас Юс Ллс Рослина, стійка до одного або більше ррх-інгібуючих гербіцидів, яка містить мутантний ген протопорфіриноген ix оксидази (ррх)
CN103237894A (zh) 2010-08-13 2013-08-07 先锋国际良种公司 包含具有羟基苯丙酮酸双加氧酶(hppd)活性的序列的组合物和方法
BR112013003223A2 (pt) 2010-08-23 2016-06-07 Pioneer Hi Bred Int "polinucleotídeo isolado, cassete de expressão, célula hospedeira, micro-organismo, planta ou parte de planta, método de obtenção de uma planta transformada, composição antipatogênica, método para proteger uma planta contra um patógeno ou uso de um polinucleotídeo isolado"
CA2816306A1 (en) 2010-10-27 2012-05-03 Danisco Us Inc. Isoprene synthase variants for improved production of isoprene
CN103562392B (zh) 2010-12-03 2016-07-20 Ms技术有限责任公司 植物细胞中草甘膦抗性编码核酸分子的优化表达
WO2012080975A1 (en) 2010-12-16 2012-06-21 Basf Se Plants having increased tolerance to herbicides
CN103261425B (zh) 2010-12-22 2015-07-15 先锋国际良种公司 病毒启动子、其截短物以及使用方法
CA2821154A1 (en) 2010-12-22 2012-06-28 Pioneer Hi-Bred International, Inc. Viral promoter, truncations thereof, and methods of use
BR112013015515A2 (pt) 2010-12-28 2018-04-24 Pioneer Hi Bred Int molécula de ácido nucleico isolada, construto de dna, célula hospedeira, planta transgênica, semente transformada da planta, polipeptídeo isolado com atividade pesticida, composição, método para controlar uma população de praga de lepidóptero, método para matar uma praga de lepidóptero, método para produzir um polipeptídeo com atividade pesticida, planta que tem incorporado de maneira estável em seu genoma um construto de dna, método para proteger uma planta contra uma praga
AR084844A1 (es) 2011-01-14 2013-06-26 Jones Jeffrey B Arboles de citricos con resistencia a cancro de los citricos
CN107603960A (zh) 2011-02-01 2018-01-19 科罗拉多小麦研究基金会公司 乙酰辅酶a羧化酶除草剂抗性植物
US9109231B2 (en) 2011-02-11 2015-08-18 Pioneer Hi Bred International Inc Synthetic insecticidal proteins active against corn rootworm
EP2675900B1 (en) 2011-02-15 2017-09-06 Pioneer Hi-Bred International, Inc. Root-preferred promoter and methods of use
US8878007B2 (en) 2011-03-10 2014-11-04 Pioneer Hi Bred International Inc Bacillus thuringiensis gene with lepidopteran activity
US8648230B2 (en) 2011-03-18 2014-02-11 Ms Technologies, Llc Regulatory regions preferentially expressing in non-pollen plant tissue
MX2013010911A (es) 2011-03-23 2015-03-03 Pioneer Hi Bred Int Metodos para producir un locus de rasgo transgenico complejo.
BR112013030638A2 (pt) 2011-03-30 2018-08-07 Univ Mexico Nac Autonoma polipeptídeo cry mutante, polinucleotídeo, cassete de expressão, célula hospedeira, planta, semente transgênica, método para proteger uma planta contra uma praga de inseto, composição pesticida, micro-organismo, método para controlar uma praga de inseto de uma área de cultivo
WO2012135501A2 (en) 2011-03-30 2012-10-04 Athenix Corp. Axmi232, axmi233, and axmi249 toxin genes and methods for their use
WO2012135436A1 (en) 2011-03-30 2012-10-04 Athenix Corp. Axmi238 toxin gene and methods for its use
UA120584C2 (uk) 2011-04-05 2020-01-10 Атенікс Корп. Варіантний інсектицидний ген axmi115 та способи його застосування
US9150625B2 (en) 2011-05-23 2015-10-06 E I Du Pont De Nemours And Company Chloroplast transit peptides and methods of their use
US20140216118A1 (en) 2011-06-14 2014-08-07 Synthon Biopharmaceuticals B.V. Compositions and Methods for Making and Biocontaining Auxotrophic Transgenic Plants
AR087167A1 (es) 2011-07-12 2014-02-26 Two Blades Foundation Genes de resistencia al tizon tardio
EP2736923A1 (en) 2011-07-28 2014-06-04 Athenix Corp. Axmi270 toxin gene and methods for its use
EP2737069B1 (en) 2011-07-28 2017-08-23 Athenix Corp. Axmi205 variant proteins and methods for their use
AR087366A1 (es) 2011-07-29 2014-03-19 Athenix Corp Gen plaguicida axmi 279 y sus metodos de empleo
US9951346B2 (en) 2011-08-03 2018-04-24 Pioneer Hi-Bred International, Inc. Methods and compositions for targeted integration in a plant
US12188028B1 (en) 2011-08-30 2025-01-07 Monsanto Technology, Llc Methods for making genetic regulatory elements
US11377663B1 (en) 2011-08-30 2022-07-05 Monsanto Technology Llc Genetic regulatory elements
AU2012301912A1 (en) 2011-08-31 2014-03-06 E. I. Dupont De Nemours & Company Methods for tissue culture and transformation of sugarcane
EP2768955A1 (en) 2011-10-19 2014-08-27 Keygene N.V. Methods and compositions for producing drimenol
US20140298544A1 (en) 2011-10-28 2014-10-02 Pioneer Hi Bred International Inc Engineered PEP carboxylase variants for improved plant productivity
FR2984076A1 (fr) 2011-12-15 2013-06-21 Inst Rech Developpement Ird Surproduction de jasmonates dans des plantes transgeniques
US20130180005A1 (en) 2012-01-06 2013-07-11 Pioneer Hi Bred International Inc Method to Screen Plants for Genetic Elements Inducing Parthenogenesis in Plants
US9006515B2 (en) 2012-01-06 2015-04-14 Pioneer Hi Bred International Inc Pollen preferred promoters and methods of use
EP2800760A1 (en) 2012-01-06 2014-11-12 Pioneer Hi-Bred International Inc. Compositions and methods for the expression of a sequence in a reproductive tissue of a plant
BR112014016791A2 (pt) 2012-01-06 2019-09-24 Pioneer Hi Bred Int molécula de ácido nucléico isolada, cassete de expressão, vetor, célula vegetal, planta, semente transgénica, método para expressão de um polinucleotídeo em uma planta ou célula vegetal, método para expressão de um polinucleotídeo, preferencialmente em tecidos de óvulo de uma planta
BR112014018294B1 (pt) 2012-01-26 2022-01-11 Norfolk Plant Sciences, Ltd Método para produzir uma planta, cassete de expressão, e, célula bacteriana
AR089793A1 (es) 2012-01-27 2014-09-17 Du Pont Metodos y composiciones para generar locus de rasgos transgenicos complejos
AR090274A1 (es) 2012-03-08 2014-10-29 Athenix Corp Gen de la toxina axmi335 de bacillus thuringiensis y sus metodos de empleo
MX362999B (es) 2012-03-08 2019-03-01 Athenix Corp Gen de la delta-endotoxina axmi345 y sus metodos de uso.
US9644213B2 (en) 2012-03-09 2017-05-09 Board Of Trustees Of Michigan State University Method of enhancing plant drought tolerance by expression of NDR1
US9163263B2 (en) 2012-05-02 2015-10-20 The Goodyear Tire & Rubber Company Identification of isoprene synthase variants with improved properties for the production of isoprene
BR112014027468A2 (pt) 2012-05-04 2017-06-27 Du Pont polinucleotídeo isolado ou recombinante, construção de dna recombinante, célula, planta, explante vegetal, semente transgênica, polipeptídeo isolado, composição, métodos de produção de meganuclease, de introdução de rompimento e de integração de um polinucleotídeo.
WO2013180809A1 (en) 2012-05-29 2013-12-05 North Carolina Central University Methods for the production of cytoprotective asialo-erythropoietin in plants and its purification from plant tissues
WO2013184764A2 (en) 2012-06-07 2013-12-12 Dow Agrosciences Llc Construct and method for expressing transgenes using a brassica bidirectional constitutive promoter
WO2013188291A2 (en) 2012-06-15 2013-12-19 E. I. Du Pont De Nemours And Company Methods and compositions involving als variants with native substrate preference
US9347105B2 (en) 2012-06-15 2016-05-24 Pioneer Hi Bred International Inc Genetic loci associated with resistance of soybean to cyst nematode and methods of use
AR091489A1 (es) 2012-06-19 2015-02-11 Basf Se Plantas que tienen una mayor tolerancia a herbicidas inhibidores de la protoporfirinogeno oxidasa (ppo)
US10041087B2 (en) 2012-06-19 2018-08-07 BASF Agro B.V. Plants having increased tolerance to herbicides
CN103998610B (zh) 2012-06-29 2020-03-17 阿森尼克斯公司 Axmi277线虫毒素及其使用方法
IN2014DN11250A (2) 2012-07-26 2015-10-09 Dow Agrosciences Llc
IN2015DN00512A (2) 2012-08-17 2015-06-26 Dow Agrosciences Llc
US9758793B2 (en) 2012-08-30 2017-09-12 Athenix Corp. AXMI-234 and AXMI-235 delta-endotoxin genes and methods for their use
US9816102B2 (en) 2012-09-13 2017-11-14 Indiana University Research And Technology Corporation Compositions and systems for conferring disease resistance in plants and methods of use thereof
UA119532C2 (uk) 2012-09-14 2019-07-10 Байєр Кропсайєнс Лп Варіант hppd та спосіб його застосування
US20150259696A1 (en) 2012-10-11 2015-09-17 Shane E. Abbitt Guard cell promoters and uses thereof
CA2887575A1 (en) 2012-10-15 2014-04-24 Pioneer Hi-Bred International, Inc. Methods and compositions to enhance activity of cry endotoxins
CN102994514B (zh) * 2012-11-07 2015-06-10 武汉禾元生物科技股份有限公司 一种从水稻种子生产和分离纯化重组人抗胰蛋白酶(OsrAAT)的方法
ES2778033T3 (es) 2012-11-16 2020-08-07 Poseida Therapeutics Inc Enzimas específicas de sitio y métodos de uso
US20140173781A1 (en) 2012-12-13 2014-06-19 Pioneer Hi-Bred International, Inc. Methods and compositions for producing and selecting transgenic wheat plants
US10253325B2 (en) 2012-12-19 2019-04-09 Boston Medical Center Corporation Methods for elevating fat/oil content in plants
CA2894213A1 (en) 2012-12-21 2014-06-26 Pioneer Hi-Bred International, Inc. Compositions and methods for auxin-analog conjugation
US20140203176A1 (en) 2013-01-23 2014-07-24 Dow Agrosciences Llc Systems and methods for real-time sampling and analysis of biomolecules beneath the surface of biological tissue
UA115896C2 (uk) 2013-02-13 2018-01-10 Атенікс Корп. Застосування токсину axmi184 для контролю кукурудзяного жука
US9783817B2 (en) 2013-03-04 2017-10-10 Arkansas State University Methods of expressing and detecting activity of expansin in plant cells
DK2964767T3 (da) 2013-03-07 2020-03-23 BASF Agricultural Solutions Seed US LLC Toksingener og fremgangsmåder til anvendelse deraf
BR112015022742A2 (pt) 2013-03-11 2018-11-27 Pionner Hi Bred Int Inc métodos e composições que empregam um domínio de estabilização dependente de sulfonilureia
BR112015022737A2 (pt) 2013-03-11 2018-04-24 Pioneer Hi-Bred International, Inc construto de polinucleotídeo recombinante, célula vegetal, planta, semente, método para regular expressão
US9243258B2 (en) 2013-03-12 2016-01-26 Pioneer Hi Bred International Inc Root-preferred promoter and methods of use
US9803214B2 (en) 2013-03-12 2017-10-31 Pioneer Hi-Bred International, Inc. Breeding pair of wheat plants comprising an MS45 promoter inverted repeat that confers male sterility and a construct that restores fertility
RU2694686C2 (ru) 2013-03-12 2019-07-16 Е.И.Дюпон Де Немур Энд Компани Способы идентификации вариантных сайтов распознавания для редкощепящих сконструированных средств для индукции двунитевого разрыва, и композиции с ними, и их применения
US9273322B2 (en) 2013-03-12 2016-03-01 Pioneer Hi Bred International Inc Root-preferred promoter and methods of use
US9416368B2 (en) 2013-03-13 2016-08-16 E I Du Pont De Nemours And Company Identification of P. pachyrhizi protein effectors and their use in producing Asian soybean rust (ASR) resistant plants
AU2014236154A1 (en) 2013-03-14 2015-09-17 Pioneer Hi-Bred International, Inc. Compositions having dicamba decarboxylase activity and methods of use
BR112015023286A2 (pt) 2013-03-14 2018-03-06 Arzeda Corp polipeptídeo recombinante com atividade da dicamba descarboxilase, construto de polinucleotídeo, célula, método de produção de uma célula hospedeira compreendendo um polinucleotídeo heterólogo que codifica um polipeptídeo tendo atividade da dicamba descarboxilase, método para descarboxilar dicamba, um derivado de dicamba ou um metabolito de dicamba, método para a detecção de um polipeptideo e método para a detecção da presença de um polinucleotideo que codifica um polipeptideo tendo atividade da dicamba descarboxilase
UA119745C2 (uk) 2013-03-14 2019-08-12 Сібас Юс Ллс Мутований ген аленоксидсинтази 2 (aos2)
CA2901316A1 (en) 2013-03-15 2014-09-25 Pioneer Hi-Bred International, Inc. Phi-4 polypeptides and methods for their use
US12331303B2 (en) 2013-03-15 2025-06-17 Cibus Us Llc Methods and compositions for increasing efficiency of targeted gene modification using oligonucleotide-mediated gene repair
ES2702289T3 (es) 2013-03-15 2019-02-28 Bayer Cropscience Lp Promotores de la soja constitutivos
US9957515B2 (en) 2013-03-15 2018-05-01 Cibus Us Llc Methods and compositions for targeted gene modification
HRP20220803T1 (hr) 2013-03-15 2022-09-30 Cibus Us Llc Postupci i kompozicije za povećanje efikasnosti modifikacije ciljanog gena korištenjem genske reparacije posredovane oligonukleotidom
EP3010939A2 (en) 2013-06-17 2016-04-27 Asana BioSciences, LLC 5t4-targeted immunofusion molecule and methods
BR112015032956B1 (pt) 2013-07-09 2022-09-13 Board Of Trustees Of Michigan State University Método para produzir uma planta transgênica e cassete de expressão
US11459579B2 (en) 2013-07-09 2022-10-04 Board Of Trustees Of Michigan State University Transgenic plants produced with a K-domain, and methods and expression cassettes related thereto
BR122022020536B1 (pt) 2013-08-08 2023-11-21 Pioneer Hi-Bred International, Inc. Molécula de ácido nucleico isolada, construto de dna, célula hospedeira bacteriana, polipeptídeo isolado, composição, método para controlar uma população, método para matar uma praga, método para produzir um polipeptídeo, método para produzir uma planta ou célula vegetal, método para proteger uma planta
WO2015038262A2 (en) 2013-08-09 2015-03-19 Athenix Corp. Axmi281 toxin gene and methods for its use
UY35696A (es) 2013-08-09 2015-03-27 Athenix Corp ?molécula de adn recombinante que comprende al gen de toxina axmi440, vector, célula huésped, plantas, composiciones y métodos relacionados?.
EP3033426A4 (en) 2013-08-12 2017-08-02 BASF Agro B.V. Plants having increased tolerance to herbicides
AU2014307664A1 (en) 2013-08-12 2016-02-18 BASF Agro B.V. Plants having increased tolerance to herbicides (PPO)
MX359026B (es) 2013-08-16 2018-09-12 Pioneer Hi Bred Int Proteinas insecticidas y metodos de uso.
CA3109801C (en) 2013-08-22 2024-01-09 Andrew Cigan Plant genome modification using guide rna/cas endonuclease systems and methods of use
EA201690560A1 (ru) 2013-09-11 2016-10-31 Пайонир Хай-Бред Интернэшнл, Инк. Регуляторные элементы растений и способы их применения
CA3223359A1 (en) 2013-09-13 2015-03-19 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
CN105764343B (zh) 2013-11-25 2020-04-17 拜耳作物科学有限合伙公司 使用axmi-011控制半翅目昆虫
AU2014364119C1 (en) 2013-12-09 2021-05-27 BASF Agricultural Solutions Seed US LLC AXMI477, AXMI482, AXMI486 and AXMI525 toxin genes from bacillus thuringiensis and methods for their use
WO2015116680A1 (en) 2014-01-30 2015-08-06 Two Blades Foundation Plants with enhanced resistance to phytophthora
CA3290904A1 (en) 2014-02-07 2026-03-02 E. I. Du Pont De Nemours And Company Insecticidal proteins and methods for their use
WO2015120270A1 (en) 2014-02-07 2015-08-13 Pioneer Hi Bred International, Inc. Insecticidal proteins and methods for their use
BR112016020889B1 (pt) 2014-03-11 2022-10-04 BASF Agricultural Solutions Seed US LLC Molécula de ácido nucleico recombinante, célula hospedeira bacteriana, proteína hppd recombinante, uso do ácido nucleico recombinante e produto de base
EA201691581A1 (ru) 2014-03-14 2017-02-28 Кибус Юс Ллс Способы и композиции для повышения эффективности направленной модификации генов с применением опосредованной олигонуклеотидами репарации генов
WO2015150465A2 (en) 2014-04-03 2015-10-08 Basf Se Plants having increased tolerance to herbicides
WO2015171603A1 (en) 2014-05-06 2015-11-12 Two Blades Foundation Methods for producing plants with enhanced resistance to oomycete pathogens
WO2015189693A1 (en) 2014-06-12 2015-12-17 King Abdullah University Of Science And Technology Targeted viral-mediated plant genome editing using crispr/cas9
AR100874A1 (es) 2014-06-16 2016-11-09 Consejo Nac De Investig Científicas Y Técnicas (Conicet) Genes quiméricos y proteínas de resistencia oxidativa, y plantas transgénicas que incluyen los mismos
AU2015288157A1 (en) 2014-07-11 2017-01-19 E. I. Du Pont De Nemours And Company Compositions and methods for producing plants resistant to glyphosate herbicide
CA2955828A1 (en) 2014-08-08 2016-02-11 Pioneer Hi-Bred International, Inc. Ubiquitin promoters and introns and methods of use
CN108064129A (zh) 2014-09-12 2018-05-22 纳幕尔杜邦公司 玉米和大豆中复合性状基因座的位点特异性整合位点的产生和使用方法
WO2016048891A1 (en) 2014-09-26 2016-03-31 Pioneer Hi-Bred International, Inc. Wheat ms1 polynucleotides, polypeptides, and mehtods of use
BR102014023930A2 (pt) 2014-09-26 2016-05-17 Ctc Ct De Tecnologia Canavieira S A método para transformar uma célula de planta ou tecido de planta usando agrobacterium, planta transgênica, célula transgênica ou tecido transgênico, meio de cultura, e, uso de um método para transformar uma célula de planta ou tecido de planta
CN106852153B (zh) 2014-10-16 2023-06-06 先锋国际良种公司 具有广谱活性的杀昆虫多肽和其用途
RU2737538C2 (ru) 2014-10-16 2020-12-01 Пайонир Хай-Бред Интернэшнл, Инк. Инсектицидные полипептиды, обладающие улучшенным спектром активности, и их применения
CA2963558C (en) 2014-10-16 2023-04-04 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
US20170369902A1 (en) 2014-12-16 2017-12-28 Pioneer Hi-Bred International, Inc. Restoration of male fertility in wheat
WO2016106184A1 (en) 2014-12-22 2016-06-30 AgBiome, Inc. Methods for making a synthetic gene
CN107635396B (zh) 2015-01-15 2021-12-24 先锋国际良种公司 杀昆虫蛋白及其使用方法
MX384801B (es) 2015-01-21 2025-04-01 Basf Se Plantas que tienen una mayor tolerancia a herbicidas.
WO2016137774A1 (en) 2015-02-25 2016-09-01 Pioneer Hi-Bred International Inc Composition and methods for regulated expression of a guide rna/cas endonuclease complex
CN107529763B (zh) 2015-03-11 2021-08-20 先锋国际良种公司 Pip-72的杀昆虫组合及使用方法
WO2016149352A1 (en) 2015-03-19 2016-09-22 Pioneer Hi-Bred International Inc Methods and compositions for accelerated trait introgression
EP3283504A1 (en) 2015-04-17 2018-02-21 Agbiome, Inc. Pesticidal genes and methods of use
AU2016252027B9 (en) 2015-04-22 2022-07-14 AgBiome, Inc. Insecticidal genes and methods of use
CN107709564B (zh) 2015-05-09 2021-11-02 双刃基金会 来自少花龙葵的抗晚疫病基因及使用方法
CN107849546A (zh) 2015-05-15 2018-03-27 先锋国际良种公司 对cas内切核酸酶系统、pam序列和指导rna元件的快速表征
CN116333064A (zh) 2015-05-19 2023-06-27 先锋国际良种公司 杀昆虫蛋白及其使用方法
CN114805503A (zh) 2015-06-03 2022-07-29 农业生物群落股份有限公司 杀虫基因和使用方法
EP3929286A1 (en) 2015-06-17 2021-12-29 Poseida Therapeutics, Inc. Compositions and methods for directing proteins to specific loci in the genome
CA2989531A1 (en) 2015-06-17 2016-12-22 BASF Agro B.V. Plants having increased tolerance to herbicides
BR112017027821A2 (pt) 2015-06-22 2019-05-14 AgBiome, Inc. genes pesticidas e métodos de uso
CA3268091A1 (en) 2015-08-06 2026-03-02 Pioneer Hi-Bred International, Inc. Plant derived insecticidal proteins and methods for their use
WO2017062790A1 (en) 2015-10-09 2017-04-13 Two Blades Foundation Cold shock protein receptors and methods of use
EP3365440B1 (en) 2015-10-20 2022-09-14 Pioneer Hi-Bred International, Inc. Restoring function to a non-functional gene product via guided cas systems and methods of use
CA3001979A1 (en) 2015-10-22 2017-04-27 Basf Se Plants having increased tolerance to herbicides
WO2017068543A1 (en) 2015-10-22 2017-04-27 Basf Se Plants having increased tolerance to herbicides
WO2017079026A1 (en) 2015-11-06 2017-05-11 E. I. Du Pont De Nemours And Company Generation of complex trait loci in soybean and methods of use
WO2017083092A1 (en) 2015-11-10 2017-05-18 Dow Agrosciences Llc Methods and systems for predicting the risk of transgene silencing
EP3384031A1 (en) 2015-11-30 2018-10-10 Pioneer Hi-Bred International, Inc. Plant regulatory elements and methods of use thereof
EP3387134B1 (en) 2015-12-11 2020-10-14 Danisco US Inc. Methods and compositions for enhanced nuclease-mediated genome modification and reduced off-target site effects
WO2017105987A1 (en) 2015-12-18 2017-06-22 Pioneer Hi-Bred International, Inc. Insecticidal proteins and methods for their use
EP3708665A1 (en) 2015-12-18 2020-09-16 Danisco US Inc. Methods and compositions for t-rna based guide rna expression
EP3394268B1 (en) 2015-12-22 2023-07-19 Pioneer Hi-Bred International, Inc. Tissue-preferred promoters and methods of use
BR112018012893A2 (pt) 2015-12-22 2018-12-04 AgBiome, Inc. genes pesticidas e métodos de uso
KR20250117482A (ko) 2016-02-09 2025-08-04 시버스 유에스 엘엘씨 올리고뉴클레오타이드 매개된 유전자 보수를 사용한 표적화된 유전자 변형의 효율을 증가시키기 위한 방법 및 조성물
CA3010628A1 (en) 2016-03-11 2017-09-14 Pioneer Hi-Bred International, Inc. Novel cas9 systems and methods of use
EP3699281A1 (en) 2016-03-11 2020-08-26 Pioneer Hi-Bred International, Inc. Novel cas9 systems and methods of use
WO2017155715A1 (en) 2016-03-11 2017-09-14 Pioneer Hi-Bred International, Inc. Novel cas9 systems and methods of use
CR20180597A (es) 2016-05-20 2019-05-07 Basf Agro Bv Péptidos de tránsito dual para el direccionamiento a polipéptidos
AU2017286122A1 (en) 2016-06-14 2018-11-22 Pioneer Hi-Bred International, Inc. Use of Cpf1 endonuclease for plant genome modifications
CA3018430A1 (en) 2016-06-20 2017-12-28 Pioneer Hi-Bred International, Inc. Novel cas systems and methods of use
AU2017294685B2 (en) 2016-07-15 2023-10-26 Basf Se Plants having increased tolerance to herbicides
WO2018019860A1 (en) 2016-07-27 2018-02-01 BASF Agro B.V. Plants having increased tolerance to herbicides
EP4219528A3 (en) 2016-09-06 2023-09-13 AgBiome, Inc. Pesticidal genes and methods of use
CA3043493A1 (en) 2016-11-23 2018-05-31 BASF Agricultural Solutions Seed US LLC Axmi669 and axmi991 toxin genes and methods for their use
WO2018112356A1 (en) 2016-12-16 2018-06-21 Two Blades Foundation Late blight resistance genes and methods of use
CN110382702A (zh) 2016-12-20 2019-10-25 巴斯夫农业公司 具有增加的除草剂耐性的植物
JP2020504609A (ja) 2016-12-22 2020-02-13 ビーエーエスエフ アグリカルチュラル ソリューションズ シード ユーエス エルエルシー 有害線虫の防除のためのｃｒｙ１４の使用
UY37571A (es) 2017-01-18 2018-08-31 Bayer Cropscience Lp Gen de toxina bp005 y procedimientos para su uso
BR112019014720A2 (pt) 2017-01-18 2020-04-07 BASF Agricultural Solutions Seed US LLC métodos para conferir resistência a doença em uma planta e para aumentar o rendimento em uma planta
WO2018140859A2 (en) 2017-01-30 2018-08-02 AgBiome, Inc. Pesticidal genes and methods of use
BR112019018056A2 (pt) 2017-03-07 2020-08-11 BASF Agricultural Solutions Seed US LLC molécula de ácido nucleico recombinante, cassete de expressão, célula hospedeira, plantas, sementes transgênicas, polipeptídeo recombinante, métodos para conferir tolerância e para controlar ervas daninhas, produto de utilidade e uso da sequência de nucleotídeos
BR112019018059A2 (pt) 2017-03-07 2020-08-04 BASF Agricultural Solutions Seed US LLC molécula de ácido nucleico recombinante, célula hospedeira, plantas, sementes transgênicas, polipeptídeo recombinante, método para produzir um polipeptídeo, método de controle de ervas daninhas, uso do ácido nucleico e produto de utilidade
CA3055389A1 (en) 2017-03-07 2018-09-13 BASF Agricultural Solutions Seed US LLC Hppd variants and methods of use
BR112019021380A2 (pt) 2017-04-11 2020-05-05 AgBiome, Inc. genes pesticidas e métodos de uso
EP3615552A1 (en) 2017-04-24 2020-03-04 DuPont Nutrition Biosciences ApS Methods and compositions of anti-crispr proteins for use in plants
WO2018202800A1 (en) 2017-05-03 2018-11-08 Kws Saat Se Use of crispr-cas endonucleases for plant genome engineering
WO2018209209A1 (en) 2017-05-12 2018-11-15 Two Blades Foundation Methods for screening proteins for pattern recognition receptor function in plant protoplasts
EP3658675A1 (en) 2017-07-28 2020-06-03 Two Blades Foundation Potyvirus resistance genes and methods of use
CN111247164A (zh) 2017-08-03 2020-06-05 农业生物群落股份有限公司 杀有害生物基因及其使用方法
JP2020536515A (ja) 2017-09-25 2020-12-17 パイオニア ハイ−ブレッド インターナショナル， インコーポレイテッド 組織優先的プロモーター及びその使用方法
WO2019083808A1 (en) 2017-10-24 2019-05-02 Basf Se IMPROVING HERBICIDE TOLERANCE AGAINST HPPD INHIBITORS BY REGULATION OF PUTATIVE REDUCED 4-HYDROXYPHENYLPYRUVATE REDUCES IN SOYBEANS
BR112020008092A2 (pt) 2017-10-24 2020-09-15 BASF Agricultural Solutions Seed US LLC método para conferir tolerância a um herbicida e planta de soja transgênica
WO2019108619A1 (en) 2017-11-28 2019-06-06 Two Blades Foundation Methods and compositions for enhancing the disease resistance of plants
WO2019106568A1 (en) 2017-11-29 2019-06-06 Basf Se Plants having increased tolerance to herbicides
CN111465689B (zh) 2017-12-15 2024-07-12 丹尼斯科美国公司 Cas9变体和使用方法
WO2019125651A1 (en) 2017-12-19 2019-06-27 Pioneer Hi-Bred International, Inc. Insecticidal polypeptides and uses thereof
WO2019126578A1 (en) 2017-12-20 2019-06-27 Poseida Therapeutics, Inc. Compositions and methods for directing proteins to specific loci in the genome
WO2019126479A1 (en) 2017-12-22 2019-06-27 AgBiome, Inc. Pesticidal genes and methods of use
WO2019133371A1 (en) 2017-12-27 2019-07-04 Pioneer Hi-Bred International, Inc. Transformation of dicot plants
WO2019140009A1 (en) 2018-01-09 2019-07-18 Cibus Us Llc Shatterproof genes and mutations
EP3737226A1 (en) 2018-01-12 2020-11-18 Two Blades Foundation Stem rust resistance genes and methods of use
AU2019210093B2 (en) 2018-01-17 2025-03-20 Basf Se Plants having increased tolerance to herbicides
WO2019157522A1 (en) 2018-02-12 2019-08-15 Curators Of The University Of Missouri Small auxin upregulated (saur) gene for the improvement of plant root system architecture, waterlogging tolerance, drought resistance and yield
KR20200124702A (ko) 2018-02-23 2020-11-03 파이어니어 하이 부렛드 인터내쇼날 인코포레이팃드 신규한 cas9 오르소로그
EP4549576A3 (en) 2018-03-12 2025-07-30 Pioneer Hi-Bred International, Inc. Methods for plant transformation
CN111954462A (zh) 2018-04-04 2020-11-17 希博斯美国有限公司 Fad2基因和突变
US11021717B2 (en) 2018-04-20 2021-06-01 AgBiome, Inc. Pesticidal genes and methods of use
CN108660151A (zh) * 2018-05-25 2018-10-16 中国林业科学研究院亚热带林业研究所 一种毛竹遗传转化的方法
BR112020024863A2 (pt) 2018-06-05 2022-02-01 Lifeedit Inc Nucleases guiadas por rna, fragmentos ativos e variantes das mesmas e métodos de uso
US20210277409A1 (en) 2018-06-28 2021-09-09 Pioneer Hi-Bred International, Inc. Methods for selecting transformed plants
US20210324398A1 (en) 2018-06-29 2021-10-21 Pioneer Hi-Bred International, Inc. Edited nac genes in plants
US20210395758A1 (en) 2018-10-31 2021-12-23 Pioneer Hi-Bred International, Inc. Compositions and methods for ochrobactrum-mediated plant transformation
US12365888B2 (en) 2018-12-14 2025-07-22 Pioneer Hi-Bred International, Inc. CRISPR-Cas systems for genome editing
ES2970169T3 (es) 2018-12-27 2024-05-27 Lifeedit Therapeutics Inc Polipéptidos útiles para edición génica y métodos de uso
BR112021017998A2 (pt) 2019-03-11 2021-11-16 Pioneer Hi Bred Int Métodos para a produção de plantas clonais
US20220170033A1 (en) 2019-03-27 2022-06-02 Pioneer Hi-Bred International, Inc. Plant explant transformation
EP3947696A1 (en) 2019-03-28 2022-02-09 Pioneer Hi-Bred International, Inc. Modified agrobacterium strains and use thereof for plant transformation
CA3136113A1 (en) 2019-04-05 2020-10-08 Danisco Us Inc. Methods for polynucleotide integration into the genome of bacillus using dual circular recombinant dna constructs and compositions thereof
US20220177923A1 (en) 2019-04-05 2022-06-09 Danisco Us Inc Methods for integrating a donor DNA sequence into the genome of bacillus using linear recombinant DNA constructs and compositions thereof
CA3131547A1 (en) 2019-04-18 2020-10-22 Pioneer Hi-Bred International, Inc. Embryogenesis factors for cellular reprogramming of a plant cell
BR112021026248A2 (pt) 2019-06-27 2022-03-03 Two Blades Found Molécula de ácido nucleico isolada que codifica uma proteína atrlp23 engenheirada, proteína atrlp23 engenheirada, cassete de expressão, vetor, célula hospedeira, planta ou célula vegetal, métodos para fazer uma proteína atrlp23 engenheirada, para fazer uma molécula de ácido nucleico que codifica uma proteína atrlp23 engenheirada e para intensificar a resistência de uma planta
WO2021011348A1 (en) 2019-07-12 2021-01-21 The Regents Of The University Of California Plants with enhanced resistance to bacterial pathogens
KR20220062289A (ko) 2019-08-12 2022-05-16 라이프에디트 테라퓨틱스, 인크. Rna-가이드된 뉴클레아제 및 그의 활성 단편 및 변이체 및 사용 방법
BR112022007119A2 (pt) 2019-10-14 2022-07-05 BASF Agricultural Solutions Seed US LLC Molécula de ácido nucleico, ácido nucleico, polipeptídeos, vetor, célula hospedeira, planta transgênica, semente transgênica, composição, métodos para controlar uma população de pragas, para matar uma praga, para produzir um polipeptídeo, para proteger uma planta e para aumentar o rendimento em uma planta, planta, uso do ácido nucleico e produto básico
AU2020367523A1 (en) 2019-10-14 2022-04-28 BASF Agricultural Solutions Seed US LLC Novel insect resistant genes and methods of use
JP2023502967A (ja) 2019-11-19 2023-01-26 ダニスコ・ユーエス・インク バチルス（Ｂａｃｉｌｌｕｓ）のゲノムを改変するための、選択マーカーを使用しない方法及びその組成物
US20230203463A1 (en) 2019-12-30 2023-06-29 LifeEDIT Therapeutics, Inc. Rna-guided nucleases and active fragments and variants thereof and methods of use
US20230056396A1 (en) * 2020-01-17 2023-02-23 Asklepios Biopharmaceutical, Inc. Systems and methods for synthetic regulatory sequence design or production
EP4110905A4 (en) 2020-02-24 2024-03-27 Pioneer Hi-Bred International, Inc. HOMOLOGOUS INTRAGENOMIC RECOMBINATION
TW202208626A (zh) 2020-04-24 2022-03-01 美商生命編輯公司 Rna引導核酸酶及其活性片段與變體，以及使用方法
CA3173882A1 (en) 2020-05-11 2021-11-18 Alexandra Briner CRAWLEY Rna-guided nucleic acid binding proteins and active fragments and variants thereof and methods of use
JP2023534693A (ja) 2020-07-15 2023-08-10 ライフエディット セラピューティクス，インコーポレイティド ウラシル安定化タンパク質並びにその活性断片及びバリアント並びに使用方法
TWI910226B (zh) 2020-09-11 2026-01-01 美商生命編輯治療學公司 Ｄｎａ修飾酶及活性片段，及其變異體與使用方法
IL301685A (en) 2020-09-30 2023-05-01 Corteva Agriscience Llc Rapid transformation of monocot leaf explants
CA3197678A1 (en) 2020-10-21 2022-04-28 Pioneer Hi-Bred International, Inc. Doubled haploid inducer
EP4231816A1 (en) 2020-10-21 2023-08-30 Pioneer Hi-Bred International, Inc. Parthenogenesis factors and methods of using same
WO2022115524A2 (en) 2020-11-24 2022-06-02 AgBiome, Inc. Pesticidal genes and methods of use
CN117295817A (zh) 2021-03-22 2023-12-26 生命编辑制药股份有限公司 Dna修饰酶及其活性片段和变体以及使用方法
CA3214227A1 (en) 2021-05-06 2022-11-10 Rebekah Deter Kelly Pesticidal genes and methods of use
BR112023023667A2 (pt) 2021-05-11 2024-01-30 Two Blades Found Métodos para preparar uma biblioteca de genes de resistência à doença de planta e à praga de planta, para identificar um gene de resistência à doença de planta e à praga de planta, para produzir uma planta com resistência aprimorada a uma doença de planta e para limitar uma doença de planta na produção de safras agrícolas, biblioteca de genes de resistência candidatos, planta transgênica, coleção de plantas transgênicas, planta ou célula de planta resistente compreendendo um gene de resistência, gene de resistência isolado, célula hospedeira, molécula de ácido nucleico, cassete de expressão, vetor, planta de trigo, semente de trigo ou célula de trigo, planta ou semente transgênica, planta, semente da planta, uso da planta ou semente, produto alimentício humano ou animal, e, polipeptídeo
AU2022290278A1 (en) 2021-06-11 2024-01-04 LifeEDIT Therapeutics, Inc. Rna polymerase iii promoters and methods of use
AU2022340861A1 (en) 2021-09-03 2024-03-14 BASF Agricultural Solutions Seed US LLC Plants having increased tolerance to herbicides
AU2022356378A1 (en) 2021-09-30 2024-05-02 Two Blades Foundation Plant disease resistance genes against stem rust and methods of use
AU2021470884A1 (en) 2021-11-01 2024-05-02 The University Of Manchester Error prone dna polymerase for organelle mutation
GB202116307D0 (en) 2021-11-12 2021-12-29 Syngenta Crop Protection Ag Herbicide resistance
US20250354160A1 (en) 2021-12-07 2025-11-20 AgBiome, Inc. Pesticidal genes and methods of use
WO2023141464A1 (en) 2022-01-18 2023-07-27 AgBiome, Inc. Method for designing synthetic nucleotide sequences
CN119317713A (zh) 2022-01-24 2025-01-14 生命编辑制药股份有限公司 Rna引导核酸酶、其活性片段与变体，及使用方法
WO2023183918A1 (en) 2022-03-25 2023-09-28 Pioneer Hi-Bred International, Inc. Methods of parthenogenic haploid induction and haploid chromosome doubling
CA3264752A1 (en) 2022-08-12 2024-02-15 Life Edit Therapeutics, Inc. RNA-GUIDED NUCLEASE AND ACTIVE FRAGMENTS, ASSOCIATED VARIANTS AND METHODS OF USE
WO2024044596A1 (en) 2022-08-23 2024-02-29 AgBiome, Inc. Pesticidal genes and methods of use
TW202424186A (zh) 2022-08-25 2024-06-16 美商生命編輯治療學公司 Rna引導核酸酶中介基因編輯用之具鎖核酸引導 rna之化學修飾
AU2023337091A1 (en) 2022-09-09 2025-03-06 Eidgenössische Technische Hochschule Zürich Plant regulatory elements and uses thereof
EP4612284A2 (en) 2022-11-04 2025-09-10 Life Edit Therapeutics, Inc. Evolved adenine deaminases and rna-guided nuclease fusion proteins with internal insertion sites and methods of use
EP4627078A1 (en) 2022-12-01 2025-10-08 Danisco US Inc. Iterative muliplex genome engineering in microbial cells using a bidirectional selection marker system
WO2024118882A1 (en) 2022-12-01 2024-06-06 Genencor International Bv Iterative multiplex genome engineering in microbial cells using a selection marker swapping system
WO2024118876A1 (en) 2022-12-01 2024-06-06 Genencor International Bv Iterative multiplex genome engineering in microbial cells using a recombinant self-excisable selection marker system
AU2023398330A1 (en) 2022-12-12 2025-06-19 Basf Agricultural Solutions Us Llc Plants having increased tolerance to herbicides
WO2024129674A1 (en) 2022-12-13 2024-06-20 AgBiome, Inc. Pesticidal genes and methods of use
AU2023408197A1 (en) 2022-12-19 2025-06-26 Basf Agricultural Solutions Us Llc Insect toxin genes and methods for their use
EP4658770A1 (en) 2023-02-03 2025-12-10 Syngenta Crop Protection AG Herbicide resistant plants
CN121152874A (zh) 2023-03-20 2025-12-16 先锋国际良种公司 具有改变的PAM识别的Cas多肽
EP4698556A1 (en) 2023-04-19 2026-02-25 Syngenta Crop Protection AG Herbicide resistant plants
WO2025111030A2 (en) 2023-07-07 2025-05-30 Basf Agricultural Solutions Us Llc Use of novel genes for the control of nematode pests
WO2025019283A1 (en) 2023-07-14 2025-01-23 Two Blades Foundation Methods of improving the thermostability of plant immune receptors
WO2025019221A1 (en) 2023-07-15 2025-01-23 Two Blades Foundation Broad-spectrum polerovirus resistance gene
WO2025022367A2 (en) 2023-07-27 2025-01-30 Life Edit Therapeutics, Inc. Rna-guided nucleases and active fragments and variants thereof and methods of use
US20250075226A1 (en) 2023-08-29 2025-03-06 University Of Freiburg Proteins for regulation of symbiotic infection and associated regulatory elements
WO2025052302A1 (en) 2023-09-05 2025-03-13 Mazen Animal Health, Inc. Methods and compositions for the production of mannanase in plants
GB202314578D0 (en) 2023-09-22 2023-11-08 Univ Manchester Methods of producing homoplasmic modified plants or parts thereof
WO2025074304A1 (en) 2023-10-03 2025-04-10 Mazen Animal Health, Inc. Compositions and methods for in planta production of a porcine circovirus vaccine
WO2025083619A1 (en) 2023-10-18 2025-04-24 Life Edit Therapeutics, Inc. Rna-guided nucleases and acive fragments and variants thereof and methods of use
WO2025090606A1 (en) 2023-10-27 2025-05-01 Basf Agricultural Solutions Us Llc Use of novel genes for the control of nematode pests
WO2025153657A2 (en) 2024-01-17 2025-07-24 Basf Se Plants having increased tolerance to herbicides
WO2025153595A1 (en) 2024-01-17 2025-07-24 Basf Se Plants having increased tolerance to herbicides
TW202546224A (zh) 2024-02-12 2025-12-01 美商生命編輯治療學公司 新穎的ｒｎａ引導之核酸酶及用於聚合酶編輯之蛋白質
WO2026003754A1 (en) 2024-06-25 2026-01-02 Life Edit Therapeutics, Inc. Novel reverse transcriptases and uses thereof
WO2026003150A1 (en) 2024-06-28 2026-01-02 Basf Se Plants with mutated tubulin polypeptide having increased tolerance to herbicides
WO2026010930A1 (en) 2024-07-05 2026-01-08 BASF Agricultural Solutions Seed US LLC Use of axmi277 for the control of rotylenchulus reniformis nematode pests

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0359472A2 (en) * 1988-09-09 1990-03-21 Mycogen Plant Science, Inc. Synthetic insecticidal crystal protein gene
WO1990010076A1 (en) * 1989-02-24 1990-09-07 Monsanto Company Synthetic plant genes and method for preparation

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR8404834A (pt) * 1983-09-26 1985-08-13 Agrigenetics Res Ass Metodo para modificar geneticamente uma celula vegetal
CA1301094C (en) * 1984-08-31 1992-05-19 Helen Riaboff Whiteley Bacillus thuringiensis crystal protein gene toxin segment
BR8600161A (pt) * 1985-01-18 1986-09-23 Plant Genetic Systems Nv Gene quimerico,vetores de plasmidio hibrido,intermediario,processo para controlar insetos em agricultura ou horticultura,composicao inseticida,processo para transformar celulas de plantas para expressar uma toxina de polipeptideo produzida por bacillus thuringiensis,planta,semente de planta,cultura de celulas e plasmidio
US4771131A (en) * 1985-08-16 1988-09-13 Mycogen Corporation Cloning and expression of Bacillus thuringiensis toxin gene encoding a protein toxic to beetles of the order Coleoptera
KR870004140A (ko) * 1985-10-28 1987-05-07 모리 히데오 살충성 단백질 유전자의 숙주 세포내 발현에 의한 바실러스 튜린지엔시스아이자와이 ipl 아종의 살충성 단백질 제조방법
CA1341092C (en) * 1985-12-12 2000-09-05 David L. Edwards Process for altering the host range of bacillus thuringiensis toxins, and novel toxins produced thereby
ZA878674B (en) * 1986-11-20 1988-08-31 Monsanto Co Insect-resistant tomato plants
SG43288A1 (en) * 1987-04-16 1997-10-17 Ecogen Inc Bacillus thuringiensis p-2 toxin gene protein and related insecticide compositions
TR27832A (tr) * 1987-04-29 1995-08-31 Monsanto Co Zararli ucucu hasarata mukavim bitkiler.
US4948734A (en) * 1987-08-12 1990-08-14 Mycogen Corporation Novel isolates of bacillus thuringiensis having activity against nematodes
TR24186A (tr) * 1988-04-11 1991-05-30 Monsanto Co Hasere zehirlerinin etkinligini arttirmak icin yoentem
EP0400246A1 (en) * 1989-05-31 1990-12-05 Plant Genetic Systems, N.V. Prevention of Bt resistance development
US5187091A (en) * 1990-03-20 1993-02-16 Ecogen Inc. Bacillus thuringiensis cryiiic gene encoding toxic to coleopteran insects
TR26973A (tr) * 1990-04-16 1994-09-12 Ecogen Inc Bacillus thuringiensis cryie geni ve lepidoptera takimindan böceklere karsi zehirli protein.
JPH05506578A (ja) * 1990-04-18 1993-09-30 プラント・ジエネテイツク・システムズ・エヌ・ベー 変性ｂａｃｉｌｌｕｓ　ｔｈｕｒｉｎｇｉｅｎｓｉｓ殺虫性結晶タンパク質遺伝子及びそれらの植物細胞中での発現
PL295547A1 (2) * 1990-04-26 1992-10-05 Plant Genetic Systems Nv
CA2064017A1 (en) * 1990-05-24 1991-11-25 Dennis E. Mccabe Particle-mediated transformation of woody plant species
CA2042868A1 (en) * 1990-06-11 1991-12-12 Kenneth E. Narva Bacillus thuringiensis microbes active against nematodes, and genes encoding novel nematode-active toxins cloned from bacillus thuringiensis isolates

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0359472A2 (en) * 1988-09-09 1990-03-21 Mycogen Plant Science, Inc. Synthetic insecticidal crystal protein gene
WO1990010076A1 (en) * 1989-02-24 1990-09-07 Monsanto Company Synthetic plant genes and method for preparation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BIO TECHNOLOGY 8 1990.1.1;BIO TECHNOLOGY 9 1991.10.1 CHRESTOU ET AL *
SCIENCL 48 1986.1.1 *

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