CN1149191C - 氮杂环丁烷衍生物,它们的制备以及含有它们的药物 - Google Patents

氮杂环丁烷衍生物,它们的制备以及含有它们的药物 Download PDF

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Publication number
CN1149191C
CN1149191C CNB99810762XA CN99810762A CN1149191C CN 1149191 C CN1149191 C CN 1149191C CN B99810762X A CNB99810762X A CN B99810762XA CN 99810762 A CN99810762 A CN 99810762A CN 1149191 C CN1149191 C CN 1149191C
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China
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methyl
methylsulfonyl
azetidine
chlorophenyl
phenyl
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Expired - Fee Related
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CNB99810762XA
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Chinese (zh)
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CN1316991A (zh
Inventor
D
D·阿查德
H·布查德
J·布克里尔
M·卡佩特
S·格里索尼
J－L·马伦
S·米格纳尼
A·希丁格
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Aventis Pharma SA
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Aventis Pharma SA
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
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    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
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    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Medicinal Chemistry (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Psychology (AREA)
  • Diabetes (AREA)
  • Addiction (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
CNB99810762XA 1998-09-11 1999-09-09 氮杂环丁烷衍生物,它们的制备以及含有它们的药物 Expired - Fee Related CN1149191C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9811342A FR2783246B1 (fr) 1998-09-11 1998-09-11 Derives d'azetidine, leur preparation et les medicaments les contenant
FR98/11342 1998-09-11
US11992999P 1999-02-12 1999-02-12
US60/119,929 1999-02-12

Publications (2)

Publication Number Publication Date
CN1316991A CN1316991A (zh) 2001-10-10
CN1149191C true CN1149191C (zh) 2004-05-12

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ID=9530327

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CNB99810762XA Expired - Fee Related CN1149191C (zh) 1998-09-11 1999-09-09 氮杂环丁烷衍生物,它们的制备以及含有它们的药物

Country Status (26)

Country Link
EP (1) EP1112251B1 (fr)
JP (1) JP4767413B2 (fr)
CN (1) CN1149191C (fr)
AR (1) AR021483A1 (fr)
AT (1) ATE239703T1 (fr)
AU (1) AU772025B2 (fr)
BR (1) BR9913592A (fr)
CA (1) CA2342739C (fr)
CO (1) CO5150230A1 (fr)
CZ (1) CZ301446B6 (fr)
DE (1) DE69907698T2 (fr)
DK (1) DK1112251T3 (fr)
DZ (1) DZ2887A1 (fr)
ES (1) ES2197666T3 (fr)
FR (1) FR2783246B1 (fr)
HU (1) HUP0103341A3 (fr)
MA (1) MA26685A1 (fr)
MY (1) MY119150A (fr)
PL (1) PL198526B1 (fr)
PT (1) PT1112251E (fr)
RU (1) RU2230739C2 (fr)
TN (1) TNSN99168A1 (fr)
TR (1) TR200100693T2 (fr)
TW (1) TW530046B (fr)
WO (1) WO2000015609A1 (fr)
ZA (1) ZA200102003B (fr)

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EP2582709B1 (fr) 2010-06-18 2018-01-24 Sanofi Dérivés d'azolopyridin-3-one en tant qu'inhibiteurs de lipases et de phospholipases
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WO2012120058A1 (fr) 2011-03-08 2012-09-13 Sanofi Dérivés d'oxathiazine substitués par des groupes benzyle ou hétérométhylène, leur procédé de production, leur utilisation comme médicament ainsi que produits pharmaceutiques les contenant et leur utilisation
EP2766349B1 (fr) 2011-03-08 2016-06-01 Sanofi Dérivés d'oxathiazine substitués par des carbocycles ou des hétérocycles, leur procédé de préparation, médicaments contenant ces composés et leur utilisation
WO2012120051A1 (fr) 2011-03-08 2012-09-13 Sanofi Dérivés benzyl-oxathiazine substitués avec adamantane ou noradamantane, médicaments contenant ces composés et leur utilisation
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DE69907698D1 (de) 2003-06-12
PL198526B1 (pl) 2008-06-30
RU2230739C2 (ru) 2004-06-20
CO5150230A1 (es) 2002-04-29
ZA200102003B (en) 2002-08-28
EP1112251B1 (fr) 2003-05-07
DZ2887A1 (fr) 2003-12-15
DE69907698T2 (de) 2004-03-25
JP4767413B2 (ja) 2011-09-07
AU772025B2 (en) 2004-04-08
HUP0103341A3 (en) 2002-10-28
WO2000015609A1 (fr) 2000-03-23
PT1112251E (pt) 2003-09-30
FR2783246A1 (fr) 2000-03-17
HUP0103341A2 (hu) 2002-02-28
CA2342739C (fr) 2009-09-08
AR021483A1 (es) 2002-07-24
ATE239703T1 (de) 2003-05-15
MA26685A1 (fr) 2004-12-20
BR9913592A (pt) 2001-06-12
TW530046B (en) 2003-05-01
TR200100693T2 (tr) 2001-07-23
FR2783246B1 (fr) 2000-11-17
TNSN99168A1 (fr) 2005-11-10
AU5523299A (en) 2000-04-03
CZ301446B6 (cs) 2010-03-03
JP2002525267A (ja) 2002-08-13
EP1112251A1 (fr) 2001-07-04
CN1316991A (zh) 2001-10-10
DK1112251T3 (da) 2003-09-01
MY119150A (en) 2005-04-30

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