CN85107520A - 2-胍基-4-(2-甲基-4-咪唑基)噻唑二氢溴化物的制备方法 - Google Patents

2-胍基-4-(2-甲基-4-咪唑基)噻唑二氢溴化物的制备方法 Download PDF

Info

Publication number: CN85107520A
Authority: CN; China
Prior art keywords: methyl; imidazolyl; temperature; inert; thiazole
Prior art date: 1984-10-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

CN198585107520A

Other languages

English (en)

Chinese (zh)

Inventor

小伯克利·温德尔·丘

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Inc

Original Assignee

Pfizer Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-11

Filing date

1985-10-10

Publication date

1986-07-23

1985-10-10 Application filed by Pfizer Inc filed Critical Pfizer Inc

1986-07-23 Publication of CN85107520A publication Critical patent/CN85107520A/zh

Status Pending legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

CN198585107520A 1984-10-11 1985-10-10 2-胍基-4-(2-甲基-4-咪唑基)噻唑二氢溴化物的制备方法 Pending CN85107520A (zh)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/659,749 US4632993A (en)	1984-10-11	1984-10-11	Process for making 2-guanidino-4-(2-methyl-4-imidazolyl) thiazole dihydrobromide
US659,749		1984-10-11

Publications (1)

Publication Number	Publication Date
CN85107520A true CN85107520A (zh)	1986-07-23

Family

ID=24646672

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CN198585107520A Pending CN85107520A (zh)	1984-10-11	1985-10-10	2-胍基-4-(2-甲基-4-咪唑基)噻唑二氢溴化物的制备方法

Country Status (16)

Country	Link
US (1)	US4632993A (2)
EP (1)	EP0178123A2 (2)
JP (1)	JPS6193181A (2)
KR (1)	KR870000278B1 (2)
CN (1)	CN85107520A (2)
AU (1)	AU558249B2 (2)
DD (1)	DD238234A5 (2)
DK (1)	DK463785A (2)
ES (1)	ES8605268A1 (2)
FI (1)	FI853949L (2)
GR (1)	GR852440B (2)
HU (1)	HUT38633A (2)
IL (1)	IL76648A0 (2)
NO (1)	NO854034L (2)
PL (1)	PL255695A1 (2)
PT (1)	PT81281B (2)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1988003140A1 (en) *	1986-10-29	1988-05-05	Pfizer Inc.	Crystalline 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazole dihydrochloride trihydrate
WO1990002127A1 (en) *	1988-08-30	1990-03-08	Pfizer Inc.	Hemiphosphate hemihydrate of 2-(1-pentyl-3-guanidino-4-imidazolyl)thiazole
CA2629077C (en) *	2005-11-16	2014-03-18	F. Hoffmann-La Roche Ag	Novel process for the preparation of thoc
EP1956018A1 (de) *	2007-02-06	2008-08-13	Boehringer Ingelheim Pharma GmbH & Co. KG	Verfahren zur Herstellung eines Benzimidazolderivats
EP4196793A1 (en)	2020-08-11	2023-06-21	Université de Strasbourg	H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4374843A (en) *	1980-10-14	1983-02-22	Pfizer Inc.	2-Guanidino-4-heteroarylthiazoles
US4435396A (en) *	1982-05-10	1984-03-06	Pfizer Inc.	Antiulcer 2-guanidino-4-(2-substituted-amino-4-imidazolyl)thiazoles and process therefor

1984
- 1984-10-11 US US06/659,749 patent/US4632993A/en not_active Expired - Lifetime
1985
- 1985-10-02 EP EP85307057A patent/EP0178123A2/en not_active Withdrawn
- 1985-10-08 GR GR852440A patent/GR852440B/el unknown
- 1985-10-09 PL PL25569585A patent/PL255695A1/xx unknown
- 1985-10-09 ES ES547713A patent/ES8605268A1/es not_active Expired
- 1985-10-09 PT PT81281A patent/PT81281B/pt unknown
- 1985-10-10 AU AU48487/85A patent/AU558249B2/en not_active Expired - Fee Related
- 1985-10-10 HU HU853943A patent/HUT38633A/hu unknown
- 1985-10-10 KR KR1019850007444A patent/KR870000278B1/ko not_active Expired
- 1985-10-10 NO NO854034A patent/NO854034L/no unknown
- 1985-10-10 DD DD85281621A patent/DD238234A5/de unknown
- 1985-10-10 CN CN198585107520A patent/CN85107520A/zh active Pending
- 1985-10-10 IL IL76648A patent/IL76648A0/xx unknown
- 1985-10-10 DK DK463785A patent/DK463785A/da not_active Application Discontinuation
- 1985-10-10 FI FI853949A patent/FI853949L/fi not_active Application Discontinuation
- 1985-10-11 JP JP60226667A patent/JPS6193181A/ja active Pending

Also Published As

Publication number	Publication date
KR870000278B1 (ko)	1987-02-23
PL255695A1 (en)	1986-07-29
ES8605268A1 (es)	1986-03-16
NO854034L (no)	1986-04-14
ES547713A0 (es)	1986-03-16
PT81281A (en)	1985-11-01
DD238234A5 (de)	1986-08-13
EP0178123A2 (en)	1986-04-16
KR860003246A (ko)	1986-05-21
AU4848785A (en)	1986-04-17
FI853949A7 (fi)	1986-04-12
IL76648A0 (en)	1986-02-28
HUT38633A (en)	1986-06-30
AU558249B2 (en)	1987-01-22
PT81281B (en)	1987-08-31
US4632993A (en)	1986-12-30
FI853949A0 (fi)	1985-10-10
JPS6193181A (ja)	1986-05-12
DK463785A (da)	1986-04-12
GR852440B (2)	1986-02-10
DK463785D0 (da)	1985-10-10
FI853949L (fi)	1986-04-12

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Legal Events

Date	Code	Title
1986-07-23	C06	Publication
1986-07-23	PB01	Publication
1988-05-04	WD01	Invention patent application deemed withdrawn after publication