CR10778A - Derivados de sulfonil-fenil-2h-[1,2,4]oxadiaxol-5-ona, procedimientos para su preparacion y su uso como agentes farmaceuticos - Google Patents

Derivados de sulfonil-fenil-2h-[1,2,4]oxadiaxol-5-ona, procedimientos para su preparacion y su uso como agentes farmaceuticos

Info

Publication number
CR10778A
CR10778A CR10778A CR10778A CR10778A CR 10778 A CR10778 A CR 10778A CR 10778 A CR10778 A CR 10778A CR 10778 A CR10778 A CR 10778A CR 10778 A CR10778 A CR 10778A
Authority
CR
Costa Rica
Prior art keywords
derivatives
oxadiaxol
sulfonil
fenil
ona
Prior art date
Application number
CR10778A
Other languages
English (en)
Inventor
Stefanie Keil
Matthias Urmann
Karl Schoenafinger
Wolfgang Wendler
Maike Glien
Hans-Ludwing Schaefer
Eugen Falk
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37998695&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR10778(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of CR10778A publication Critical patent/CR10778A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P35/00—Antineoplastic agents
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    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Reproductive Health (AREA)
  • Ophthalmology & Optometry (AREA)

Abstract

La invencion se refiere a sulfonil-fenil-oxadiazolonas y a sus sales fisiologicamente aceptables y derivados fisiologicamente funcionales que muestran actividad agonista de PPARdelta o PPARdelta o PPARdelta y PPARgamma. Lo que se describe son compuestos de la formula I, en la que los radicales son como se han definido, y sus sales fisiologicamente aceptables, y procedimientos para sus preparaciones.
CR10778A 2006-12-14 2009-05-07 Derivados de sulfonil-fenil-2h-[1,2,4]oxadiaxol-5-ona, procedimientos para su preparacion y su uso como agentes farmaceuticos CR10778A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06025880A EP1932843A1 (en) 2006-12-14 2006-12-14 Sulfonyl-phenyl-2H-(1,2,4) oxadiazole-5-one derivatives, processes for their preparation and their use as pharmaceuticals

Publications (1)

Publication Number Publication Date
CR10778A true CR10778A (es) 2009-06-24

Family

ID=37998695

Family Applications (1)

Application Number Title Priority Date Filing Date
CR10778A CR10778A (es) 2006-12-14 2009-05-07 Derivados de sulfonil-fenil-2h-[1,2,4]oxadiaxol-5-ona, procedimientos para su preparacion y su uso como agentes farmaceuticos

Country Status (24)

Country Link
US (1) US8173674B2 (es)
EP (2) EP1932843A1 (es)
JP (1) JP2010512352A (es)
KR (1) KR20090087922A (es)
CN (1) CN101558064A (es)
AR (1) AR064299A1 (es)
AU (1) AU2007331805A1 (es)
BR (1) BRPI0720416A2 (es)
CA (1) CA2672347A1 (es)
CL (1) CL2007003614A1 (es)
CO (1) CO6210729A2 (es)
CR (1) CR10778A (es)
EC (1) ECSP099409A (es)
MA (1) MA30981B1 (es)
MX (1) MX2009005535A (es)
NO (1) NO20092293L (es)
PE (1) PE20081404A1 (es)
RU (1) RU2009126745A (es)
SV (1) SV2009003293A (es)
TN (1) TN2009000242A1 (es)
TW (1) TW200843749A (es)
UY (1) UY30783A1 (es)
WO (1) WO2008071311A1 (es)
ZA (1) ZA200903160B (es)

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JPWO2004080943A1 (ja) * 2003-03-11 2006-06-08 小野薬品工業株式会社 シンナミルアルコール誘導体化合物およびその化合物を有効成分として含有する薬剤
US20060258683A1 (en) 2003-04-07 2006-11-16 Liu Kevin Para-sulfonyl substituted phenyl compounds as modulators of ppars
DE10335449A1 (de) 2003-08-02 2005-02-17 Bayer Healthcare Ag Bicyclische Indolinsulfonamid-Derivate
EP1586573B1 (en) * 2004-04-01 2007-02-07 Sanofi-Aventis Deutschland GmbH Oxadiazolones, processes for their preparation and their use as pharmaceuticals

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NO20092293L (no) 2009-09-08
EP2102198A1 (en) 2009-09-23
AU2007331805A1 (en) 2008-06-19
US8173674B2 (en) 2012-05-08
WO2008071311A1 (en) 2008-06-19
EP2102198B1 (en) 2015-02-25
MA30981B1 (fr) 2009-12-01
MX2009005535A (es) 2009-06-05
TW200843749A (en) 2008-11-16
AR064299A1 (es) 2009-03-25
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EP1932843A1 (en) 2008-06-18
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CL2007003614A1 (es) 2008-06-20
BRPI0720416A2 (pt) 2013-12-31
CO6210729A2 (es) 2010-10-20
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RU2009126745A (ru) 2011-01-20
CA2672347A1 (en) 2008-06-19
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