CR11819A - Compuestos de isoindolina 5-sustituidos - Google Patents

Compuestos de isoindolina 5-sustituidos

Info

Publication number
CR11819A
CR11819A CR11819A CR11819A CR11819A CR 11819 A CR11819 A CR 11819A CR 11819 A CR11819 A CR 11819A CR 11819 A CR11819 A CR 11819A CR 11819 A CR11819 A CR 11819A
Authority
CR
Costa Rica
Prior art keywords
substituted isoindoline
isoindoline compounds
compounds
substituted
prodrugs
Prior art date
Application number
CR11819A
Other languages
English (en)
Inventor
George W Muller
Roger S Chen
Alexander L Ruchelman
Hon-Wah Man
Weihong Zhang
Ehab M Khalil
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of CR11819A publication Critical patent/CR11819A/es

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
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Abstract

La invención se refiere a compuestos de isoindolina 5-sustituida, y las sales, solvatos, estereoisómeros, y profármacos de los mismos aceptables farmacéuticamente. Se describen métodos de uso, y composiciones farmacéuticas de estos compuestos.
CR11819A 2008-05-30 2010-11-30 Compuestos de isoindolina 5-sustituidos CR11819A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/130,445 US8877780B2 (en) 2006-08-30 2008-05-30 5-substituted isoindoline compounds

Publications (1)

Publication Number Publication Date
CR11819A true CR11819A (es) 2011-03-23

Family

ID=41048037

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IL209664A0 (en) 2011-02-28
BRPI0912111A2 (pt) 2015-10-06
JP2011522803A (ja) 2011-08-04
JP5990379B2 (ja) 2016-09-14
MX2010013107A (es) 2010-12-21
WO2009145899A1 (en) 2009-12-03
EP3061758B1 (en) 2018-01-31
US20090142297A1 (en) 2009-06-04
ES2665964T3 (es) 2018-04-30
AU2009251815A8 (en) 2011-01-20
ZA201008486B (en) 2012-01-25
JP2015227331A (ja) 2015-12-17
CA2725603C (en) 2016-10-25
EP2291365B1 (en) 2015-03-11
US9447070B2 (en) 2016-09-20
RU2010154130A (ru) 2012-07-10
MX341197B (es) 2016-08-11
EP3327013B1 (en) 2019-04-24
US20160346264A1 (en) 2016-12-01
US20150005303A1 (en) 2015-01-01
EP2749559A1 (en) 2014-07-02
EP2291365A1 (en) 2011-03-09
EP2749559B1 (en) 2016-04-27
NI201000205A (es) 2011-08-29
CN102112463A (zh) 2011-06-29
KR20110019761A (ko) 2011-02-28
AU2009251815A1 (en) 2009-12-03
ECSP10010724A (es) 2011-02-28
CO6331337A2 (es) 2011-10-20
ES2736450T3 (es) 2019-12-30
EP3327013A1 (en) 2018-05-30
MX346608B (es) 2017-03-27
JP6215253B2 (ja) 2017-10-18
US8877780B2 (en) 2014-11-04
HK1202856A1 (en) 2015-10-09
ES2577454T3 (es) 2016-07-15
CA2725603A1 (en) 2009-12-03
US9801868B2 (en) 2017-10-31
ES2535290T3 (es) 2015-05-08

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