CR20190131A - 1-arilnaftiridin-3-carboxamidas 7-sustituidas y su uso - Google Patents
1-arilnaftiridin-3-carboxamidas 7-sustituidas y su usoInfo
- Publication number
- CR20190131A CR20190131A CR20190131A CR20190131A CR20190131A CR 20190131 A CR20190131 A CR 20190131A CR 20190131 A CR20190131 A CR 20190131A CR 20190131 A CR20190131 A CR 20190131A CR 20190131 A CR20190131 A CR 20190131A
- Authority
- CR
- Costa Rica
- Prior art keywords
- para
- diseases
- naphthyridine
- aryl
- substituted
- Prior art date
Links
- 230000002265 prevention Effects 0.000 abstract 3
- 238000011282 treatment Methods 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000017169 kidney disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Braking Arrangements (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16188728.6A EP3296298A1 (de) | 2016-09-14 | 2016-09-14 | 7-substituierte 1-aryl-naphthyridin-3-carbonsäureamide und ihre verwendung |
| EP16202509 | 2016-12-06 | ||
| PCT/EP2017/072339 WO2018050510A1 (de) | 2016-09-14 | 2017-09-06 | 7-substituierte 1-aryl-naphthyridin-3-carbonsäureamide und ihre verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR20190131A true CR20190131A (es) | 2019-05-15 |
Family
ID=59966701
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR20190131A CR20190131A (es) | 2016-09-14 | 2017-09-06 | 1-arilnaftiridin-3-carboxamidas 7-sustituidas y su uso |
Country Status (40)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20180252A1 (es) | 2015-06-09 | 2018-02-02 | Bayer Pharma AG | Moduladores alostericos positivos del receptor muscarinico m2 |
| CN109689654A (zh) | 2016-07-11 | 2019-04-26 | 拜耳医药股份有限公司 | 7-取代的1-吡啶基-萘啶-3-甲酰胺类及其用途 |
| JOP20190045A1 (ar) | 2016-09-14 | 2019-03-14 | Bayer Ag | مركبات أميد حمض 1- أريل-نفثيريدين-3-كربوكسيليك مستبدلة في الموضع 7 واستخدامها. |
| CN115605609A (zh) * | 2020-04-08 | 2023-01-13 | 拜耳公司（De） | 使用rt-pcr的病毒感染的快速检测 |
| US12569481B2 (en) | 2020-06-12 | 2026-03-10 | Vanderbilt University | Methods of treatment for gastrointestinal motility disorders |
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| DE3508816A1 (de) | 1985-01-10 | 1986-07-10 | Bayer Ag, 5090 Leverkusen | 6,7-disubstituierte 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphtyridin-3-carbonsaeuren |
| DE3906365A1 (de) * | 1988-07-15 | 1990-01-18 | Bayer Ag | 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe |
| DE4301246A1 (de) | 1993-01-19 | 1994-07-21 | Bayer Ag | Chinolon- und Naphthyridoncarbonsäurederivate |
| EP0713487B1 (en) * | 1993-08-13 | 2000-04-19 | Dong Wha Pharmaceutical Industrial Co. Ltd. | Novel quinolone carboxylic acid derivatives |
| US6136823A (en) | 1996-11-28 | 2000-10-24 | Wakunaga Pharmaceutical Co., Ltd. | Pyridonecarboxylic acid derivatives or salts thereof and drugs containing the same as the active ingredient |
| DE19834044A1 (de) | 1998-07-29 | 2000-02-03 | Bayer Ag | Neue substituierte Pyrazolderivate |
| DE19834047A1 (de) | 1998-07-29 | 2000-02-03 | Bayer Ag | Substituierte Pyrazolderivate |
| DE19943636A1 (de) | 1999-09-13 | 2001-03-15 | Bayer Ag | Neuartige Dicarbonsäurederivate mit pharmazeutischen Eigenschaften |
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| DE19943639A1 (de) | 1999-09-13 | 2001-03-15 | Bayer Ag | Dicarbonsäurederivate mit neuartigen pharmazeutischen Eigenschaften |
| AR031176A1 (es) | 2000-11-22 | 2003-09-10 | Bayer Ag | Nuevos derivados de pirazolpiridina sustituidos con piridina |
| DE10110749A1 (de) | 2001-03-07 | 2002-09-12 | Bayer Ag | Substituierte Aminodicarbonsäurederivate |
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| DE10220570A1 (de) | 2002-05-08 | 2003-11-20 | Bayer Ag | Carbamat-substituierte Pyrazolopyridine |
| JP2005012561A (ja) | 2003-06-19 | 2005-01-13 | Sony Corp | 画像処理装置、画像処理方法および画像投射装置 |
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| CN102964350A (zh) * | 2012-09-20 | 2013-03-13 | 杨文� | 一种7-六氢吡咯并[1,2-a]吡嗪基喹诺酮羧酸衍生物及其在治疗幽门螺杆菌感染应用 |
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| JP6549735B2 (ja) | 2015-06-09 | 2019-07-24 | アッヴィ・インコーポレイテッド | 核内受容体調節剤 |
| MX375707B (es) | 2015-06-09 | 2025-03-06 | Onconic Therapeutics Inc | Compuesto derivativo triciclico, metodo para prepararlo y composicion farmaceutica que comprende el mismo. |
| PE20180252A1 (es) * | 2015-06-09 | 2018-02-02 | Bayer Pharma AG | Moduladores alostericos positivos del receptor muscarinico m2 |
| CN109689654A (zh) | 2016-07-11 | 2019-04-26 | 拜耳医药股份有限公司 | 7-取代的1-吡啶基-萘啶-3-甲酰胺类及其用途 |
| JOP20190045A1 (ar) | 2016-09-14 | 2019-03-14 | Bayer Ag | مركبات أميد حمض 1- أريل-نفثيريدين-3-كربوكسيليك مستبدلة في الموضع 7 واستخدامها. |
-
2017
- 2017-06-16 JO JOP/2019/0045A patent/JOP20190045A1/ar unknown
- 2017-09-06 BR BR112019004982A patent/BR112019004982A2/pt not_active IP Right Cessation
- 2017-09-06 MY MYPI2019001243A patent/MY196473A/en unknown
- 2017-09-06 PL PL17772322T patent/PL3512849T3/pl unknown
- 2017-09-06 CN CN202211273380.7A patent/CN115429798A/zh active Pending
- 2017-09-06 TN TNP/2019/000083A patent/TN2019000083A1/en unknown
- 2017-09-06 ES ES17772322T patent/ES2887674T3/es active Active
- 2017-09-06 EP EP17772322.8A patent/EP3512849B1/de active Active
- 2017-09-06 DK DK17772322.8T patent/DK3512849T3/da active
- 2017-09-06 CN CN202211273001.4A patent/CN115477649A/zh active Pending
- 2017-09-06 LT LTEPPCT/EP2017/072339T patent/LT3512849T/lt unknown
- 2017-09-06 UA UAA201903730A patent/UA125627C2/uk unknown
- 2017-09-06 GE GEAP202115045A patent/GEAP202115045A/en unknown
- 2017-09-06 CU CU2019000020A patent/CU24618B1/es unknown
- 2017-09-06 SI SI201730869T patent/SI3512849T1/sl unknown
- 2017-09-06 HR HRP20211396TT patent/HRP20211396T1/hr unknown
- 2017-09-06 MA MA46235A patent/MA46235B1/fr unknown
- 2017-09-06 PE PE2019000524A patent/PE20190803A1/es unknown
- 2017-09-06 NZ NZ751297A patent/NZ751297A/en not_active IP Right Cessation
- 2017-09-06 MX MX2019003007A patent/MX379715B/es unknown
- 2017-09-06 CN CN202211273015.6A patent/CN115554294A/zh active Pending
- 2017-09-06 GE GEAP201715045A patent/GEP20217332B/en unknown
- 2017-09-06 AU AU2017326297A patent/AU2017326297B2/en not_active Ceased
- 2017-09-06 CN CN201780056605.4A patent/CN109689656B/zh not_active Expired - Fee Related
- 2017-09-06 KR KR1020197007039A patent/KR20190046851A/ko not_active Withdrawn
- 2017-09-06 SG SG11201901973RA patent/SG11201901973RA/en unknown
- 2017-09-06 CR CR20190131A patent/CR20190131A/es unknown
- 2017-09-06 KR KR1020237006804A patent/KR20230035437A/ko not_active Abandoned
- 2017-09-06 WO PCT/EP2017/072339 patent/WO2018050510A1/de not_active Ceased
- 2017-09-06 JP JP2019535448A patent/JP7295019B2/ja active Active
- 2017-09-06 US US16/333,079 patent/US10927109B2/en not_active Expired - Fee Related
- 2017-09-06 CA CA3036497A patent/CA3036497A1/en active Pending
- 2017-09-06 RS RS20211093A patent/RS62299B1/sr unknown
- 2017-09-06 HU HUE17772322A patent/HUE056343T2/hu unknown
- 2017-09-14 TW TW106131572A patent/TWI758325B/zh not_active IP Right Cessation
- 2017-09-14 UY UY0001037403A patent/UY37403A/es unknown
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2019
- 2019-02-28 IL IL265106A patent/IL265106B/en unknown
- 2019-03-12 PH PH12019500535A patent/PH12019500535A1/en unknown
- 2019-03-14 CO CONC2019/0002361A patent/CO2019002361A2/es unknown
- 2019-03-14 DO DO2019000060A patent/DOP2019000060A/es unknown
- 2019-03-14 NI NI201900023A patent/NI201900023A/es unknown
- 2019-03-14 CL CL2019000670A patent/CL2019000670A1/es unknown
- 2019-03-14 EC ECSENADI201918116A patent/ECSP19018116A/es unknown
- 2019-04-12 ZA ZA2019/02325A patent/ZA201902325B/en unknown
-
2021
- 2021-01-28 US US17/161,186 patent/US20220089591A1/en not_active Abandoned
- 2021-01-28 US US17/161,201 patent/US11472803B2/en active Active
- 2021-09-02 CY CY20211100782T patent/CY1124492T1/el unknown
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