MA46235A - 1-aryl-naphtyridin-3-ylcarboxamides substitués en position 7 et leur utilisation - Google Patents

1-aryl-naphtyridin-3-ylcarboxamides substitués en position 7 et leur utilisation

Info

Publication number: MA46235A
Authority: MA; Morocco
Prior art keywords: ylcarboxamides; naphtyridin; aryl; substituted; ylcarboxamides substituted
Prior art date: 2016-09-14

Application number

MA046235A

Other languages

English (en)

Other versions

MA46235B1 (fr

Inventor

Arapinis Melissa Boultadakis

Markus Brechmann

Till Freudenberger

Maximilian Andreas Kullmann

Tobias Marquardt

Thomas Mondritzki

Alexander Straub

Henrik Teller

Hanna Tinel

Alexandros Vakalopoulos

Matthias Beat Wittwer

Original Assignee

Bayer Ag

Bayer Pharma AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2016-09-14

Filing date

2017-09-06

Publication date

2021-04-14

2016-09-14 Priority claimed from EP16188728.6A external-priority patent/EP3296298A1/fr

2017-09-06 Application filed by Bayer Ag, Bayer Pharma AG filed Critical Bayer Ag

2021-04-14 Publication of MA46235A publication Critical patent/MA46235A/fr

2021-10-29 Publication of MA46235B1 publication Critical patent/MA46235B1/fr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyridine Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Braking Arrangements (AREA)

MA46235A 2016-09-14 2017-09-06 1-aryl-naphtyridin-3-ylcarboxamides substitués en position 7 et leur utilisation MA46235B1 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP16188728.6A EP3296298A1 (fr)	2016-09-14	2016-09-14	1-aryl-naphtyridin-3-ylcarboxamides substitués en position 7 et leur utilisation
EP16202509		2016-12-06
PCT/EP2017/072339 WO2018050510A1 (fr)	2016-09-14	2017-09-06	Amides de l'acide 1-aryl-naphthyridine-3-carboxylique substitués en position 7 et leur utilisation

Publications (2)

Publication Number	Publication Date
MA46235A true MA46235A (fr)	2021-04-14
MA46235B1 MA46235B1 (fr)	2021-10-29

Family

ID=59966701

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA46235A MA46235B1 (fr)	2016-09-14	2017-09-06	1-aryl-naphtyridin-3-ylcarboxamides substitués en position 7 et leur utilisation

Country Status (40)

Country	Link
US (3)	US10927109B2 (fr)
EP (1)	EP3512849B1 (fr)
JP (1)	JP7295019B2 (fr)
KR (2)	KR20230035437A (fr)
CN (4)	CN115477649A (fr)
AU (1)	AU2017326297B2 (fr)
BR (1)	BR112019004982A2 (fr)
CA (1)	CA3036497A1 (fr)
CL (1)	CL2019000670A1 (fr)
CO (1)	CO2019002361A2 (fr)
CR (1)	CR20190131A (fr)
CU (1)	CU24618B1 (fr)
CY (1)	CY1124492T1 (fr)
DK (1)	DK3512849T3 (fr)
DO (1)	DOP2019000060A (fr)
EC (1)	ECSP19018116A (fr)
ES (1)	ES2887674T3 (fr)
GE (2)	GEAP202115045A (fr)
HR (1)	HRP20211396T1 (fr)
HU (1)	HUE056343T2 (fr)
IL (1)	IL265106B (fr)
JO (1)	JOP20190045A1 (fr)
LT (1)	LT3512849T (fr)
MA (1)	MA46235B1 (fr)
MX (1)	MX379715B (fr)
MY (1)	MY196473A (fr)
NI (1)	NI201900023A (fr)
NZ (1)	NZ751297A (fr)
PE (1)	PE20190803A1 (fr)
PH (1)	PH12019500535A1 (fr)
PL (1)	PL3512849T3 (fr)
RS (1)	RS62299B1 (fr)
SG (1)	SG11201901973RA (fr)
SI (1)	SI3512849T1 (fr)
TN (1)	TN2019000083A1 (fr)
TW (1)	TWI758325B (fr)
UA (1)	UA125627C2 (fr)
UY (1)	UY37403A (fr)
WO (1)	WO2018050510A1 (fr)
ZA (1)	ZA201902325B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2016198342A1 (fr)	2015-06-09	2016-12-15	Bayer Pharma Aktiengesellschaft	Modulateurs positivement allostériques du récepteur muscarinique m2
CA3030204A1 (fr)	2016-07-11	2018-01-18	Bayer Pharma Aktiengesellschaft	Amides de l'acide 1-pyridyl-naphthyridin-3-carboxylique substitues en position 7, et leur utilisation
JOP20190045A1 (ar)	2016-09-14	2019-03-14	Bayer Ag	مركبات أميد حمض 1- أريل-نفثيريدين-3-كربوكسيليك مستبدلة في الموضع 7 واستخدامها.
JP2023521783A (ja) *	2020-04-08	2023-05-25	バイエル、アクチエンゲゼルシャフト	Ｒｔ－ｐｃｒを用いたウイルス感染の迅速な検出
WO2021252951A1 (fr)	2020-06-12	2021-12-16	Vanderbilt University	Méthodes de traitement de troubles de motilité gastro-intestinale

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JP2017538689A (ja)	2014-11-17	2017-12-28	ニーロジョンセラピューティクスインコーポレイテッドＮｉｒｏｇｙｏｎｅＴｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ．	モノカルボン酸輸送修飾薬およびその使用
RS59934B1 (sr)	2015-06-09	2020-03-31	Abbvie Inc	Modulatori nuklearnih receptora (ror) za lečenje inflamatornih i autoimunih oboljenja
WO2016198342A1 (fr) *	2015-06-09	2016-12-15	Bayer Pharma Aktiengesellschaft	Modulateurs positivement allostériques du récepteur muscarinique m2
KR101837047B1 (ko)	2015-06-09	2018-03-09	제일약품주식회사	트리사이클릭 유도체 화합물, 이의 제조방법 및 이를 포함하는 약학적 조성물
CA3030204A1 (fr)	2016-07-11	2018-01-18	Bayer Pharma Aktiengesellschaft	Amides de l'acide 1-pyridyl-naphthyridin-3-carboxylique substitues en position 7, et leur utilisation
JOP20190045A1 (ar)	2016-09-14	2019-03-14	Bayer Ag	مركبات أميد حمض 1- أريل-نفثيريدين-3-كربوكسيليك مستبدلة في الموضع 7 واستخدامها.

2017
- 2017-06-16 JO JOP/2019/0045A patent/JOP20190045A1/ar unknown
- 2017-09-06 TN TNP/2019/000083A patent/TN2019000083A1/en unknown
- 2017-09-06 JP JP2019535448A patent/JP7295019B2/ja active Active
- 2017-09-06 PE PE2019000524A patent/PE20190803A1/es unknown
- 2017-09-06 PL PL17772322T patent/PL3512849T3/pl unknown
- 2017-09-06 CA CA3036497A patent/CA3036497A1/fr active Pending
- 2017-09-06 WO PCT/EP2017/072339 patent/WO2018050510A1/fr not_active Ceased
- 2017-09-06 RS RS20211093A patent/RS62299B1/sr unknown
- 2017-09-06 US US16/333,079 patent/US10927109B2/en not_active Expired - Fee Related
- 2017-09-06 GE GEAP202115045A patent/GEAP202115045A/en unknown
- 2017-09-06 CN CN202211273001.4A patent/CN115477649A/zh active Pending
- 2017-09-06 CN CN202211273015.6A patent/CN115554294A/zh active Pending
- 2017-09-06 AU AU2017326297A patent/AU2017326297B2/en not_active Ceased
- 2017-09-06 NZ NZ751297A patent/NZ751297A/en not_active IP Right Cessation
- 2017-09-06 BR BR112019004982A patent/BR112019004982A2/pt not_active IP Right Cessation
- 2017-09-06 CU CU2019000020A patent/CU24618B1/es unknown
- 2017-09-06 SI SI201730869T patent/SI3512849T1/sl unknown
- 2017-09-06 EP EP17772322.8A patent/EP3512849B1/fr active Active
- 2017-09-06 CR CR20190131A patent/CR20190131A/es unknown
- 2017-09-06 MX MX2019003007A patent/MX379715B/es unknown
- 2017-09-06 CN CN202211273380.7A patent/CN115429798A/zh active Pending
- 2017-09-06 DK DK17772322.8T patent/DK3512849T3/da active
- 2017-09-06 CN CN201780056605.4A patent/CN109689656B/zh not_active Expired - Fee Related
- 2017-09-06 HU HUE17772322A patent/HUE056343T2/hu unknown
- 2017-09-06 KR KR1020237006804A patent/KR20230035437A/ko not_active Abandoned
- 2017-09-06 ES ES17772322T patent/ES2887674T3/es active Active
- 2017-09-06 LT LTEPPCT/EP2017/072339T patent/LT3512849T/lt unknown
- 2017-09-06 UA UAA201903730A patent/UA125627C2/uk unknown
- 2017-09-06 MA MA46235A patent/MA46235B1/fr unknown
- 2017-09-06 KR KR1020197007039A patent/KR20190046851A/ko not_active Withdrawn
- 2017-09-06 SG SG11201901973RA patent/SG11201901973RA/en unknown
- 2017-09-06 GE GEAP201715045A patent/GEP20217332B/en unknown
- 2017-09-06 HR HRP20211396TT patent/HRP20211396T1/hr unknown
- 2017-09-06 MY MYPI2019001243A patent/MY196473A/en unknown
- 2017-09-14 UY UY0001037403A patent/UY37403A/es unknown
- 2017-09-14 TW TW106131572A patent/TWI758325B/zh not_active IP Right Cessation
2019
- 2019-02-28 IL IL265106A patent/IL265106B/en unknown
- 2019-03-12 PH PH12019500535A patent/PH12019500535A1/en unknown
- 2019-03-14 CO CONC2019/0002361A patent/CO2019002361A2/es unknown
- 2019-03-14 NI NI201900023A patent/NI201900023A/es unknown
- 2019-03-14 EC ECSENADI201918116A patent/ECSP19018116A/es unknown
- 2019-03-14 CL CL2019000670A patent/CL2019000670A1/es unknown
- 2019-03-14 DO DO2019000060A patent/DOP2019000060A/es unknown
- 2019-04-12 ZA ZA2019/02325A patent/ZA201902325B/en unknown
2021
- 2021-01-28 US US17/161,201 patent/US11472803B2/en active Active
- 2021-01-28 US US17/161,186 patent/US20220089591A1/en not_active Abandoned
- 2021-09-02 CY CY20211100782T patent/CY1124492T1/el unknown

Also Published As

Publication number	Publication date
KR20230035437A (ko)	2023-03-13
IL265106B (en)	2022-05-01
CY1124492T1 (el)	2022-07-22
NI201900023A (es)	2019-05-23
NZ751297A (en)	2022-12-23
CN115477649A (zh)	2022-12-16
PE20190803A1 (es)	2019-06-10
CN109689656A (zh)	2019-04-26
PH12019500535A1 (en)	2019-11-04
DOP2019000060A (es)	2019-04-15
US20190263805A1 (en)	2019-08-29
ZA201902325B (en)	2022-03-30
PL3512849T3 (pl)	2021-11-29
ECSP19018116A (es)	2019-03-29
MX379715B (es)	2025-03-11
LT3512849T (lt)	2021-08-25
MX2019003007A (es)	2019-07-18
MA46235B1 (fr)	2021-10-29
CA3036497A1 (fr)	2018-03-22
CO2019002361A2 (es)	2019-06-19
KR20190046851A (ko)	2019-05-07
UY37403A (es)	2018-04-30
CN109689656B (zh)	2022-10-04
AU2017326297A1 (en)	2019-03-28
CN115429798A (zh)	2022-12-06
CL2019000670A1 (es)	2019-08-02
CU20190020A7 (es)	2019-11-04
AU2017326297B2 (en)	2021-07-29
US11472803B2 (en)	2022-10-18
US10927109B2 (en)	2021-02-23
BR112019004982A2 (pt)	2019-08-20
GEAP202115045A (en)	2021-08-10
EP3512849A1 (fr)	2019-07-24
HRP20211396T1 (hr)	2021-12-10
CU24618B1 (es)	2022-08-09
SI3512849T1 (sl)	2021-10-29
TWI758325B (zh)	2022-03-21
ES2887674T3 (es)	2021-12-27
GEP20217332B (en)	2021-12-10
JP7295019B2 (ja)	2023-06-20
EP3512849B1 (fr)	2021-06-23
DK3512849T3 (da)	2021-08-16
US20220089591A1 (en)	2022-03-24
JOP20190045A1 (ar)	2019-03-14
MY196473A (en)	2023-04-12
RS62299B1 (sr)	2021-09-30
CN115554294A (zh)	2023-01-03
TN2019000083A1 (en)	2020-07-15
HUE056343T2 (hu)	2022-02-28
JP2019534320A (ja)	2019-11-28
WO2018050510A1 (fr)	2018-03-22
TW201811785A (zh)	2018-04-01
UA125627C2 (uk)	2022-05-04
CR20190131A (es)	2019-05-15
US20210261541A1 (en)	2021-08-26
SG11201901973RA (en)	2019-04-29

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