CR7959A - Proceso para preparar derivados de feniletilamina - Google Patents

Proceso para preparar derivados de feniletilamina

Info

Publication number
CR7959A
CR7959A CR7959A CR7959A CR7959A CR 7959 A CR7959 A CR 7959A CR 7959 A CR7959 A CR 7959A CR 7959 A CR7959 A CR 7959A CR 7959 A CR7959 A CR 7959A
Authority
CR
Costa Rica
Prior art keywords
alkyl
hydrogen
prepare
compound
formula
Prior art date
Application number
CR7959A
Other languages
English (en)
Inventor
Keun-Sik Kim
Kwang-Il Kim
Ki-Byung Chai
Original Assignee
Wyeth Corp
Elan Pharma Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32990789&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR7959(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Corp, Elan Pharma Int Ltd filed Critical Wyeth Corp
Publication of CR7959A publication Critical patent/CR7959A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Proceso para preparar un compuesto de formula (I), en donde R1 y R2 son sustituyentes en posicion orto o para, seleccionados independientemente entre el grupo integrado por hidrogeno, hidroxilo, alquilo de 1a 6 C, alcoxilo de 1 a 6 C, arilalcoxilo de 7 a 9 C, alcanoiloxilo de 2 a 7 C, alquilmercapto de 1 a 6 C, halogeno y trifluorometilo; R3 es hidrogeno o alquilo de 1 a 6 C; R4 es hidrogeno, alquilo de 1 a 6 C, formilo o alcanoilo de 2 a 7 C; n es un numero entero que puede ser 0,1,2,3, o 4; y la linea de puntos representa una instauracion olefinica opcional; que comprende la hidrogenacion de un compuesto de formula (III), en presencia de un catalizador de niquel o de cobalto a una temperatura entre aproximadamente 5 C y 25 C.
CR7959A 2003-03-11 2005-08-23 Proceso para preparar derivados de feniletilamina CR7959A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45358303P 2003-03-11 2003-03-11

Publications (1)

Publication Number Publication Date
CR7959A true CR7959A (es) 2006-05-31

Family

ID=32990789

Family Applications (1)

Application Number Title Priority Date Filing Date
CR7959A CR7959A (es) 2003-03-11 2005-08-23 Proceso para preparar derivados de feniletilamina

Country Status (20)

Country Link
US (2) US7179944B2 (es)
EP (1) EP1601640A2 (es)
JP (1) JP2006520391A (es)
KR (1) KR20050106102A (es)
CN (1) CN100480231C (es)
AR (1) AR043538A1 (es)
AU (1) AU2004220055A1 (es)
BR (1) BRPI0408300A (es)
CA (1) CA2517164A1 (es)
CL (1) CL2004000492A1 (es)
CO (1) CO5611119A2 (es)
CR (1) CR7959A (es)
EC (1) ECSP056012A (es)
MX (1) MXPA05009555A (es)
NO (1) NO20054300L (es)
RU (1) RU2005131420A (es)
SG (1) SG160193A1 (es)
TW (1) TWI306092B (es)
WO (1) WO2004080934A2 (es)
ZA (1) ZA200507297B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6342533B1 (en) 1998-12-01 2002-01-29 Sepracor, Inc. Derivatives of (−)-venlafaxine and methods of preparing and using the same
PL350924A1 (en) * 1999-04-06 2003-02-10 Sepracor Inc Derivatives of venlafaxine and methods of preparing and using the same
DE60221642T3 (de) 2001-02-12 2017-10-26 Wyeth LLC (n.d.Ges.d. Staates Delaware) O-desmethyl-venlafaxine succinat salz
WO2006067808A1 (en) * 2004-12-22 2006-06-29 Calyx Chemicals & Pharmaceuticals Private Limited An improved process for production of intermediate of antidepressant agent
US7196223B2 (en) * 2005-05-03 2007-03-27 Solutia, Inc. Higher alcohols for solvents in amine production
CN1955159B (zh) 2005-06-17 2010-11-24 山东绿叶制药有限公司 用于阻断5-羟色胺以及去甲基肾上腺素再摄取的化合物,其制备方法及其用途
JP2009500420A (ja) * 2005-07-06 2009-01-08 セプラコア インコーポレーテッド エスゾピクロン及びｏ−デスメチルベンラファキシンの組み合わせ、並びに閉経期並びに気分、不安、及び認知障害の治療方法
KR20080056311A (ko) * 2005-10-19 2008-06-20 테바 파마슈티컬 인더스트리즈 리미티드 고순도1-[2-디메틸아미노-(4-메톡시페닐)에틸)시클로헥산올염산염의 제조 방법
WO2007069277A2 (en) * 2005-11-30 2007-06-21 Aarti Healthcare Limited A process for the preparation of venlafaxine hydrochloride
MX2007016179A (es) 2006-04-17 2008-03-11 Teva Pharma Formas cristalinas de o-desmetilvenlafaxina.
US20080221356A1 (en) * 2006-07-26 2008-09-11 Valerie Niddam-Hildesheim Processes for the synthesis of O-desmethylvenlafaxine
EP1934167A2 (en) * 2006-07-26 2008-06-25 Teva Pharmaceutical Industries Ltd. Processes for the synthesis of o-desmethylvenlafaxine
CA2656285A1 (en) * 2006-07-26 2008-01-31 Teva Pharmaceutical Industries Ltd. Processes for the synthesis of o-desmethylvenlafaxine
US20090137846A1 (en) * 2006-07-26 2009-05-28 Valerie Niddam-Hildesheim Processes for the synthesis of O-Desmethylvenlafaxine
WO2008015584A2 (en) * 2006-08-04 2008-02-07 Medichem, S.A. Improved process for synthesizing desvenlafaxine free base and salts or solvates thereof
WO2008109093A1 (en) * 2007-03-06 2008-09-12 Exxonmobil Research And Engineering Company Fiber reinforced polypropylene composite front end modules
KR20100132069A (ko) * 2008-06-16 2010-12-16 테바 파마슈티컬 인더스트리즈 리미티드 Ｏ-데스메틸벤라팍신염의 고체 상태
US20100016638A1 (en) * 2008-07-21 2010-01-21 Zdenko Hamersak Method for preparation of o-desmethylvenlafaxine using polythiolates
WO2010100520A1 (en) * 2009-03-04 2010-09-10 Hikal Limited A process for preparation of phenethylamine derivative
WO2011121452A2 (en) * 2010-03-29 2011-10-06 Pliva Hrvatska D.O.O. Crystal forms of o-desmethylvenlafaxine fumarate
CZ303249B6 (cs) 2010-04-06 2012-06-20 Zentiva, K.S. Zpusob výroby 4-(2-(substituovaných)-1-(1-hydroxycyklohexyl)ethyl)fenolu O-demethylací jejich methyletheru pomocí nepáchnoucích aromatických thiolu
US8933123B2 (en) 2010-10-08 2015-01-13 Cadila Healthcare Limited Polymorphic forms of O-desmethyl-venlafaxine succinate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535186A (en) * 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
JP2811065B2 (ja) 1985-12-02 1998-10-15 ダイセル化学工業株式会社 ベンジルアミンの製造法
PL350924A1 (en) * 1999-04-06 2003-02-10 Sepracor Inc Derivatives of venlafaxine and methods of preparing and using the same
AU2002238421A1 (en) * 2000-12-20 2002-07-01 Ciba Specialty Chemicals Holding Inc. Process for the preparation of phenethylamine derivatives
AU2002220961A1 (en) * 2000-12-21 2002-07-01 Inca International S.P.A. Use of osmotic membranes in therephthalic acid production

Also Published As

Publication number Publication date
RU2005131420A (ru) 2006-04-20
US7179944B2 (en) 2007-02-20
SG160193A1 (en) 2010-04-29
WO2004080934A2 (en) 2004-09-23
EP1601640A2 (en) 2005-12-07
AR043538A1 (es) 2005-08-03
US7563931B2 (en) 2009-07-21
CL2004000492A1 (es) 2005-02-04
US20070149813A1 (en) 2007-06-28
TWI306092B (en) 2009-02-11
CN100480231C (zh) 2009-04-22
CO5611119A2 (es) 2006-02-28
BRPI0408300A (pt) 2006-03-07
CN1756733A (zh) 2006-04-05
KR20050106102A (ko) 2005-11-08
MXPA05009555A (es) 2005-10-19
AU2004220055A1 (en) 2004-09-23
JP2006520391A (ja) 2006-09-07
ZA200507297B (en) 2010-02-24
US20040181093A1 (en) 2004-09-16
NO20054300L (no) 2005-09-30
ECSP056012A (es) 2006-01-27
WO2004080934A3 (en) 2004-10-28
TW200427657A (en) 2004-12-16
CA2517164A1 (en) 2004-09-23

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)