CR8698A - Anticuerpos monoclonales al factor de crecimiento de hepatocito - Google Patents

Anticuerpos monoclonales al factor de crecimiento de hepatocito

Info

Publication number
CR8698A
CR8698A CR8698A CR8698A CR8698A CR 8698 A CR8698 A CR 8698A CR 8698 A CR8698 A CR 8698A CR 8698 A CR8698 A CR 8698A CR 8698 A CR8698 A CR 8698A
Authority
CR
Costa Rica
Prior art keywords
growth factor
hepatocite
monoclonal antibodies
pharmaceutical composition
administering
Prior art date
Application number
CR8698A
Other languages
English (en)
Inventor
Kyung Jin Kim
Yi-Chi Su
Original Assignee
Galaxy Biotech Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35320045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR8698(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Galaxy Biotech Llc filed Critical Galaxy Biotech Llc
Publication of CR8698A publication Critical patent/CR8698A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invencion es concerniente con un anticuerpo monoclonal neutralizante al factor crecimiento de hepatocito, una composicion farmaceutica que comprende el mismo y metodo de tratamiento que comprenden administrar tal composicion farmaceutica a un paciente, tal como para inhibir glioblastoma.
CR8698A 2004-04-15 2006-10-19 Anticuerpos monoclonales al factor de crecimiento de hepatocito CR8698A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/825,060 US20040208876A1 (en) 2003-04-18 2004-04-15 Monoclonal antibodies to hepatocyte growth factor

Publications (1)

Publication Number Publication Date
CR8698A true CR8698A (es) 2007-12-17

Family

ID=35320045

Family Applications (1)

Application Number Title Priority Date Filing Date
CR8698A CR8698A (es) 2004-04-15 2006-10-19 Anticuerpos monoclonales al factor de crecimiento de hepatocito

Country Status (25)

Country Link
US (5) US20040208876A1 (es)
EP (2) EP1734995B1 (es)
JP (2) JP4594381B2 (es)
KR (1) KR101072736B1 (es)
CN (1) CN1964738A (es)
AT (1) ATE473760T1 (es)
AU (1) AU2004319276C1 (es)
BR (1) BRPI0418745A (es)
CA (1) CA2563080C (es)
CR (1) CR8698A (es)
CY (1) CY1110783T1 (es)
DE (1) DE602004028168D1 (es)
DK (1) DK1734995T3 (es)
ES (1) ES2346886T3 (es)
HR (1) HRP20100521T1 (es)
IL (1) IL178474A (es)
MX (1) MXPA06011822A (es)
NO (1) NO20065227L (es)
NZ (1) NZ550324A (es)
PL (1) PL1734995T3 (es)
PT (1) PT1734995E (es)
RU (1) RU2361879C2 (es)
SI (1) SI1734995T1 (es)
WO (1) WO2005107800A1 (es)
ZA (1) ZA200609407B (es)

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AR059922A1 (es) * 2006-04-01 2008-05-07 Galaxy Biotech Llc Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos
JP5754875B2 (ja) 2006-04-07 2015-07-29 国立大学法人大阪大学 筋再生促進剤
US7649083B2 (en) 2006-06-02 2010-01-19 Aveo Pharmaceuticals, Inc. Hepatocyte growth factor (HGF) binding antibody
AU2007254853B2 (en) 2006-06-02 2011-11-17 Aveo Pharmaceuticals, Inc. Hepatocyte growth factor (HGF) binding proteins
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CL2009000843A1 (es) * 2008-04-11 2009-07-24 Galaxy Biotech Llc Metodo para tratar cancer en un paciente que comprende la administracion de un primer agente que es inhibidor de factor de crecimiento de hepatocito (hgf) en combinacion con un segundo agente que es inhibidor de una ruta de senalizacion celular diferente de la ruta hgf/cmet.
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KR20140067052A (ko) 2011-09-09 2014-06-03 암젠 인코퍼레이티드 식도암 및 위암 환자들에서 항-간세포 성장 인자（“ｈｇｆ”） 항체들의 유효성을 예측하기 위한 ｃ―ｍｅｔ 단백질의 용도
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WO2014153166A2 (en) * 2013-03-14 2014-09-25 Alder Biopharmaceuticals, Inc. Therapeutic use of antibodies to hgf
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WO2018203545A1 (ja) 2017-05-02 2018-11-08 国立研究開発法人国立精神・神経医療研究センター Ｉｌ－６及び好中球の関連する疾患の治療効果の予測及び判定方法
JP7235249B2 (ja) 2017-10-20 2023-03-08 学校法人兵庫医科大学 抗ｉｌ－６受容体抗体を含有する術後の癒着を抑制するための医薬組成物
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Also Published As

Publication number Publication date
ATE473760T1 (de) 2010-07-15
US7494650B2 (en) 2009-02-24
US20040208876A1 (en) 2004-10-21
IL178474A0 (en) 2007-02-11
IL178474A (en) 2011-04-28
HRP20100521T1 (hr) 2010-10-31
EP1734995B1 (en) 2010-07-14
US20090104192A1 (en) 2009-04-23
US20070160613A1 (en) 2007-07-12
AU2004319276C1 (en) 2011-03-03
AU2004319276B2 (en) 2010-08-26
NZ550324A (en) 2009-12-24
EP2204191A1 (en) 2010-07-07
CA2563080C (en) 2015-01-27
HK1094167A1 (en) 2007-03-23
CY1110783T1 (el) 2015-06-10
SI1734995T1 (sl) 2010-09-30
CA2563080A1 (en) 2005-11-17
KR20070012711A (ko) 2007-01-26
EP1734995A1 (en) 2006-12-27
EP1734995A4 (en) 2007-04-25
KR101072736B1 (ko) 2011-10-11
AU2004319276A1 (en) 2005-11-17
NO20065227L (no) 2007-01-10
US7687063B2 (en) 2010-03-30
WO2005107800A1 (en) 2005-11-17
BRPI0418745A (pt) 2007-12-11
ES2346886T3 (es) 2010-10-21
DE602004028168D1 (de) 2010-08-26
JP2011012067A (ja) 2011-01-20
PL1734995T3 (pl) 2010-12-31
ZA200609407B (en) 2008-07-30
JP2007532643A (ja) 2007-11-15
RU2361879C2 (ru) 2009-07-20
MXPA06011822A (es) 2007-03-23
US20080019966A1 (en) 2008-01-24
RU2006140257A (ru) 2008-05-20
CN1964738A (zh) 2007-05-16
PT1734995E (pt) 2010-08-18
US20120064066A1 (en) 2012-03-15
JP4594381B2 (ja) 2010-12-08
DK1734995T3 (da) 2010-10-25

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