CR8918A - Derivados de triazolopiridinilsulfanilo como inhibidores de quinasa map p38 - Google Patents

Derivados de triazolopiridinilsulfanilo como inhibidores de quinasa map p38

Info

Publication number
CR8918A
CR8918A CR8918A CR8918A CR8918A CR 8918 A CR8918 A CR 8918A CR 8918 A CR8918 A CR 8918A CR 8918 A CR8918 A CR 8918A CR 8918 A CR8918 A CR 8918A
Authority
CR
Costa Rica
Prior art keywords
triazolopiridinilsulfanilo
quinasa
inhibitors
map
derivatives
Prior art date
Application number
CR8918A
Other languages
English (en)
Inventor
Paul Mathias John
Simon Millan David
Andrew Lewthwaite Rusell
Phillips Chistopher
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0418015A external-priority patent/GB0418015D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of CR8918A publication Critical patent/CR8918A/es

Links

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Reproductive Health (AREA)

Abstract

Un compuesto de formula (I), o un sal y/o solvato (incluyendo un hidrato) farmaceuticamente aceptable del mismo; y el uso de un compuesto de formula (I) en el tratamiento de una enfermedad, trastorno o afeccion mediada por TNF, o una enfermedad, trastorno o afeccion mediada por p38, en particular las enfermedades alergicas y no alergicas de las vias respiratorias, mas particularmente enfermedades obstructivas o inflamatorias de las vias respiratorias, preferiblemente la enfermedad pulmonar obstructiva cronica.
CR8918A 2004-08-12 2007-02-09 Derivados de triazolopiridinilsulfanilo como inhibidores de quinasa map p38 CR8918A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0418015A GB0418015D0 (en) 2004-08-12 2004-08-12 New compounds
US69155905P 2005-06-17 2005-06-17

Publications (1)

Publication Number Publication Date
CR8918A true CR8918A (es) 2007-04-02

Family

ID=35783420

Family Applications (1)

Application Number Title Priority Date Filing Date
CR8918A CR8918A (es) 2004-08-12 2007-02-09 Derivados de triazolopiridinilsulfanilo como inhibidores de quinasa map p38

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US (2) US7511057B2 (es)
EP (1) EP1778686B9 (es)
JP (1) JP4084836B2 (es)
AP (1) AP2326A (es)
AR (1) AR050692A1 (es)
AT (1) ATE412652T1 (es)
AU (1) AU2005273612B2 (es)
BR (1) BRPI0514255A (es)
CA (1) CA2576297C (es)
CR (1) CR8918A (es)
CU (1) CU23497A3 (es)
CY (1) CY1108788T1 (es)
DE (1) DE602005010714D1 (es)
DK (1) DK1778686T3 (es)
EA (1) EA012119B1 (es)
EC (1) ECSP077232A (es)
ES (1) ES2314690T3 (es)
GE (1) GEP20104973B (es)
GT (1) GT200500218A (es)
HN (1) HN2005000418A (es)
HR (1) HRP20080608T3 (es)
IL (1) IL181047A (es)
MA (1) MA28798B1 (es)
MX (1) MX2007001759A (es)
MY (1) MY140021A (es)
NL (1) NL1029726C2 (es)
NO (1) NO339320B1 (es)
NZ (1) NZ552868A (es)
PL (1) PL1778686T3 (es)
PT (1) PT1778686E (es)
SI (1) SI1778686T1 (es)
SV (1) SV2006002193A (es)
TN (1) TNSN07050A1 (es)
WO (1) WO2006018718A2 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7572807B2 (en) * 2005-06-09 2009-08-11 Bristol-Myers Squibb Company Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors
US7579360B2 (en) * 2005-06-09 2009-08-25 Bristol-Myers Squibb Company Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
US20090012079A1 (en) * 2006-02-09 2009-01-08 Russell Andrew Lewthwaite Triazolopyridine Compounds
JP5244369B2 (ja) * 2006-11-10 2013-07-24 富士フイルム株式会社 ５−アミノピラゾール誘導体の製造方法、アゾ色素
EP1992344A1 (en) 2007-05-18 2008-11-19 Institut Curie P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation
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