CU23497A3 - Derivados de triazolopiridinilsulfanilo como inhibidores de quinasa map p38 - Google Patents

Derivados de triazolopiridinilsulfanilo como inhibidores de quinasa map p38

Info

Publication number
CU23497A3
CU23497A3 CU20070042A CU20070042A CU23497A3 CU 23497 A3 CU23497 A3 CU 23497A3 CU 20070042 A CU20070042 A CU 20070042A CU 20070042 A CU20070042 A CU 20070042A CU 23497 A3 CU23497 A3 CU 23497A3
Authority
CU
Cuba
Prior art keywords
formula
triazolopiridinilsulfanilo
quinasa
inhibitors
map
Prior art date
Application number
CU20070042A
Other languages
English (en)
Inventor
Christopher Phillips
David Simon Millan
Rusell Andrew Lewthwaite
John Paul Mathias
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0418015A external-priority patent/GB0418015D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of CU23497A3 publication Critical patent/CU23497A3/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
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Abstract

Un compuesto de fórmula (I), o un sal y/o solvato (incluyendo un hidrato) farmacéuticamente aceptable del mismo; ESPACIO PARA FÓRMULA y el uso de un compuesto de fórmula (I) en el tratamiento de una enfermedad, trastornos o afección mediante por TNF, o una enfermedad, trastorno o afección mediada por p38, en particular las enfermedades alérgicas y no alérgicas de las vías respiratorias, más particularmente enfermedades obstructivas o inflamatorias de las vías respiratorias, preferiblemente la enfermedad pulmonar obstrutiva crónica.
CU20070042A 2004-08-12 2007-02-08 Derivados de triazolopiridinilsulfanilo como inhibidores de quinasa map p38 CU23497A3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0418015A GB0418015D0 (en) 2004-08-12 2004-08-12 New compounds
US69155905P 2005-06-17 2005-06-17

Publications (1)

Publication Number Publication Date
CU23497A3 true CU23497A3 (es) 2010-03-25

Family

ID=35783420

Family Applications (1)

Application Number Title Priority Date Filing Date
CU20070042A CU23497A3 (es) 2004-08-12 2007-02-08 Derivados de triazolopiridinilsulfanilo como inhibidores de quinasa map p38

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US (2) US7511057B2 (es)
EP (1) EP1778686B9 (es)
JP (1) JP4084836B2 (es)
AP (1) AP2326A (es)
AR (1) AR050692A1 (es)
AT (1) ATE412652T1 (es)
AU (1) AU2005273612B2 (es)
BR (1) BRPI0514255A (es)
CA (1) CA2576297C (es)
CR (1) CR8918A (es)
CU (1) CU23497A3 (es)
CY (1) CY1108788T1 (es)
DE (1) DE602005010714D1 (es)
DK (1) DK1778686T3 (es)
EA (1) EA012119B1 (es)
EC (1) ECSP077232A (es)
ES (1) ES2314690T3 (es)
GE (1) GEP20104973B (es)
GT (1) GT200500218A (es)
HN (1) HN2005000418A (es)
HR (1) HRP20080608T3 (es)
IL (1) IL181047A (es)
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NZ (1) NZ552868A (es)
PL (1) PL1778686T3 (es)
PT (1) PT1778686E (es)
SI (1) SI1778686T1 (es)
SV (1) SV2006002193A (es)
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WO (1) WO2006018718A2 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7572807B2 (en) * 2005-06-09 2009-08-11 Bristol-Myers Squibb Company Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors
US7579360B2 (en) * 2005-06-09 2009-08-25 Bristol-Myers Squibb Company Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
US20090012079A1 (en) * 2006-02-09 2009-01-08 Russell Andrew Lewthwaite Triazolopyridine Compounds
JP5244369B2 (ja) * 2006-11-10 2013-07-24 富士フイルム株式会社 ５−アミノピラゾール誘導体の製造方法、アゾ色素
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