CR9048A - Analogos de anilino-pirimidina - Google Patents
Analogos de anilino-pirimidinaInfo
- Publication number
- CR9048A CR9048A CR9048A CR9048A CR9048A CR 9048 A CR9048 A CR 9048A CR 9048 A CR9048 A CR 9048A CR 9048 A CR9048 A CR 9048A CR 9048 A CR9048 A CR 9048A
- Authority
- CR
- Costa Rica
- Prior art keywords
- anilino
- pyrimidine analogs
- pyrimidine
- analogs
- compounds
- Prior art date
Links
- 150000008059 anilinopyrimidines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
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- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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Abstract
La presente invencion se relaciona con compuestos de formula I: en donde R1, R2, R3, R4, R5 y R6 son como se definio aqui.
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| WO2002016352A1 (en) * | 2000-08-21 | 2002-02-28 | Astrazeneca Ab | Quinazoline derivatives |
| GB0021726D0 (en) * | 2000-09-05 | 2000-10-18 | Astrazeneca Ab | Chemical compounds |
| US7122544B2 (en) | 2000-12-06 | 2006-10-17 | Signal Pharmaceuticals, Llc | Anilinopyrimidine derivatives as IKK inhibitors and compositions and methods related thereto |
| BR0116452A (pt) * | 2000-12-21 | 2003-09-30 | Glaxo Group Ltd | Composto, composição farmacêutica, uso de um composto |
| US20020132823A1 (en) * | 2001-01-17 | 2002-09-19 | Jiahuai Han | Assay method |
| GB0103926D0 (en) * | 2001-02-17 | 2001-04-04 | Astrazeneca Ab | Chemical compounds |
| ES2316546T3 (es) * | 2001-02-20 | 2009-04-16 | Astrazeneca Ab | 2-arilamino-pirimidinas para el tratamiento de trastornos asociados a gsk3. |
| CA2441733A1 (en) * | 2001-03-29 | 2002-10-10 | Vertex Pharmaceuticals Incorporated | Inhibitors of c-jun n-terminal kinases (jnk) and other protein kinases |
| WO2002083668A1 (en) * | 2001-04-10 | 2002-10-24 | Vertex Pharmaceuticals Incorporated | Isoxaxole derivatives as inhibitors of src and other protein kinases |
| AU2002338642A1 (en) * | 2001-04-13 | 2002-10-28 | Vertex Pharmaceuticals Incorporated | Inhibitors of c-jun n-terminal kinases (jnk) and other protein kinases |
| WO2002092573A2 (en) * | 2001-05-16 | 2002-11-21 | Vertex Pharmaceuticals Incorporated | Heterocyclic substituted pyrazoles as inhibitors of src and other protein kinases |
| BR0209774A (pt) * | 2001-05-29 | 2004-06-01 | Schering Ag | Pirimidinas inibidoras de cdk, sua preparação e aplicação como medicamento |
| ES2274035T3 (es) * | 2001-06-01 | 2007-05-16 | Vertex Pharmaceuticals Incorporated | Compuestos de tiazol utiles como inhibidores de proteina quinasas. |
| CA2450769A1 (en) * | 2001-06-15 | 2002-12-27 | Vertex Pharmaceuticals Incorporated | 5-(2-aminopyrimidin-4-yl) benzisoxazoles as protein kinase inhibitors |
| US6939874B2 (en) * | 2001-08-22 | 2005-09-06 | Amgen Inc. | Substituted pyrimidinyl derivatives and methods of use |
| US6703414B2 (en) * | 2001-09-14 | 2004-03-09 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Device and method for treating restenosis |
| AU2003209077A1 (en) * | 2002-02-08 | 2003-09-02 | Smithkline Beecham Corporation | Pyrimidine compounds |
| AU2003220970A1 (en) * | 2002-03-01 | 2003-09-16 | Smithkline Beecham Corporation | Diamino-pyrimidines and their use as angiogenesis inhibitors |
| US7442697B2 (en) | 2002-03-09 | 2008-10-28 | Astrazeneca Ab | 4-imidazolyl substituted pyrimidine derivatives with CDK inhibitory activity |
| GB0215844D0 (en) * | 2002-07-09 | 2002-08-14 | Novartis Ag | Organic compounds |
| AU2003286876A1 (en) * | 2002-11-01 | 2004-06-07 | Vertex Pharmaceuticals Incorporated | Compositions useful as inhibitors of jak and other protein kinases |
| EP1560824A1 (en) * | 2002-11-05 | 2005-08-10 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of jak and other protein kinases |
| GB0226582D0 (en) | 2002-11-14 | 2002-12-18 | Cyclacel Ltd | Anti-viral compounds |
| GB0226583D0 (en) * | 2002-11-14 | 2002-12-18 | Cyclacel Ltd | Compounds |
-
2005
- 2005-10-13 JP JP2007536838A patent/JP2008515986A/ja active Pending
- 2005-10-13 US US11/248,495 patent/US7799915B2/en not_active Expired - Fee Related
- 2005-10-13 WO PCT/US2005/036674 patent/WO2006044457A1/en not_active Ceased
- 2005-10-13 AU AU2005295788A patent/AU2005295788A1/en not_active Abandoned
- 2005-10-13 RU RU2007114080/04A patent/RU2007114080A/ru not_active Application Discontinuation
- 2005-10-13 AR ARP050104293A patent/AR051387A1/es not_active Application Discontinuation
- 2005-10-13 GT GT200500286A patent/GT200500286A/es unknown
- 2005-10-13 PE PE2005001207A patent/PE20060582A1/es not_active Application Discontinuation
- 2005-10-13 CA CA002580913A patent/CA2580913A1/en not_active Abandoned
- 2005-10-13 KR KR1020077010445A patent/KR20070084067A/ko not_active Withdrawn
- 2005-10-13 CN CNA2005800349350A patent/CN101039919A/zh not_active Withdrawn
- 2005-10-13 MX MX2007004488A patent/MX2007004488A/es unknown
- 2005-10-13 PA PA20058649401A patent/PA8649401A1/es unknown
- 2005-10-13 TW TW094135620A patent/TW200626559A/zh unknown
- 2005-10-13 BR BRPI0516597-0A patent/BRPI0516597A/pt not_active IP Right Cessation
- 2005-10-13 EP EP05812654A patent/EP1799652A1/en not_active Withdrawn
-
2007
- 2007-03-28 NO NO20071642A patent/NO20071642L/no not_active Application Discontinuation
- 2007-03-29 IL IL182316A patent/IL182316A0/en unknown
- 2007-04-11 CR CR9048A patent/CR9048A/es unknown
- 2007-04-12 ZA ZA200703022A patent/ZA200703022B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200703022B (en) | 2009-04-29 |
| PA8649401A1 (es) | 2006-09-22 |
| AU2005295788A1 (en) | 2006-04-27 |
| TW200626559A (en) | 2006-08-01 |
| NO20071642L (no) | 2007-06-01 |
| GT200500286A (es) | 2006-06-13 |
| WO2006044457A1 (en) | 2006-04-27 |
| BRPI0516597A (pt) | 2008-09-16 |
| JP2008515986A (ja) | 2008-05-15 |
| KR20070084067A (ko) | 2007-08-24 |
| US7799915B2 (en) | 2010-09-21 |
| AR051387A1 (es) | 2007-01-10 |
| US20060079543A1 (en) | 2006-04-13 |
| MX2007004488A (es) | 2007-09-11 |
| IL182316A0 (en) | 2007-07-24 |
| PE20060582A1 (es) | 2006-08-17 |
| CA2580913A1 (en) | 2006-04-27 |
| CN101039919A (zh) | 2007-09-19 |
| RU2007114080A (ru) | 2008-11-27 |
| EP1799652A1 (en) | 2007-06-27 |
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