CR9723A - Nueva forma cristalina de un derivado de piridazino[4,5-b] indol - Google Patents

Nueva forma cristalina de un derivado de piridazino[4,5-b] indol

Info

Publication number
CR9723A
CR9723A CR9723A CR9723A CR9723A CR 9723 A CR9723 A CR 9723A CR 9723 A CR9723 A CR 9723A CR 9723 A CR9723 A CR 9723A CR 9723 A CR9723 A CR 9723A
Authority
CR
Costa Rica
Prior art keywords
piridazino
indol
derivative
crystal form
new crystal
Prior art date
Application number
CR9723A
Other languages
English (en)
Inventor
L Rocco William
D Higgins John
Original Assignee
Sanofi Aventis Us Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37546937&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR9723(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis Us Llc filed Critical Sanofi Aventis Us Llc
Publication of CR9723A publication Critical patent/CR9723A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Se describe una nueva forma cristalina de 7-cloro-N,N,5-trimetil-4-oxo-3-fenil-3,5-dihidro-4H-piridazino[4,5-b]indol-1-acetamida, procesos para preparar dicha forma cristalina de 7-cloro-N,N,5-trimetil-4-oxo-3-fenil-3,5-dihidro-4H-piridazino[4,5-b]indol-1-acetamida, composiciones que comprenden dicha forma mazclada con uno o mas excipientes farmaceuticamente aceptables, y usos para la misma.
CR9723A 2005-08-29 2008-02-11 Nueva forma cristalina de un derivado de piridazino[4,5-b] indol CR9723A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71215305P 2005-08-29 2005-08-29

Publications (1)

Publication Number Publication Date
CR9723A true CR9723A (es) 2008-06-18

Family

ID=37546937

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9723A CR9723A (es) 2005-08-29 2008-02-11 Nueva forma cristalina de un derivado de piridazino[4,5-b] indol

Country Status (31)

Country Link
US (1) US7683062B2 (es)
EP (1) EP1924585B1 (es)
JP (1) JP5063600B2 (es)
KR (2) KR20130087059A (es)
CN (1) CN101253176B (es)
AR (1) AR057099A1 (es)
AT (1) ATE531717T1 (es)
AU (1) AU2006285142B2 (es)
BR (1) BRPI0615259A2 (es)
CA (1) CA2619284C (es)
CR (1) CR9723A (es)
CY (1) CY1112317T1 (es)
DK (1) DK1924585T3 (es)
EA (1) EA014164B1 (es)
EC (1) ECSP088209A (es)
ES (1) ES2375841T3 (es)
HR (1) HRP20120073T1 (es)
IL (1) IL189276A (es)
MA (1) MA30000B1 (es)
NO (1) NO20081365L (es)
NZ (1) NZ566087A (es)
PL (1) PL1924585T3 (es)
PT (1) PT1924585E (es)
RS (1) RS52318B (es)
SI (1) SI1924585T1 (es)
TN (1) TNSN08059A1 (es)
TW (1) TW200813060A (es)
UA (1) UA91716C2 (es)
UY (1) UY29771A1 (es)
WO (1) WO2007027525A1 (es)
ZA (1) ZA200801890B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2678125C (en) * 2003-11-17 2014-10-14 Merck Eprova Ag Crystalline forms of (6r)-l-erythro-tetrahydrobiopterin dihydrochloride
ES2370829T3 (es) * 2004-06-02 2011-12-23 Sandoz Ag Producto intermedio de meropenem en forma cristalina.
AU2006298881A1 (en) * 2005-09-21 2007-04-12 4Sc Ag Sulphonylpyrrole hydrochloride salts as histone deacetylases inhibitors
NZ567357A (en) * 2005-10-31 2011-05-27 Janssen Pharmaceutica Nv Novel processes for the preparation of piperazinyl and diazapanyl benzamide derivatives
CA2656057C (en) * 2006-06-16 2012-10-02 H. Lundbeck A/S Crystalline forms of 4-[2-(4-methylphenylsulfanyl)-phenyl]piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain
KR20090084891A (ko) * 2006-10-27 2009-08-05 시그날 파마소티칼 엘엘씨 4-[9-(테트라하이드로-퓨란-3-일)-8-(2,4,6-트리플루오로-페닐아미노)-9ｈ-퓨린-2-일아미노]-사이클로헥산-1-올을 포함하는 고체 형태들, 이들의 조성물들 및 이들의 용도
EP2085397A1 (en) * 2008-01-21 2009-08-05 Esteve Quimica, S.A. Crystalline form of abacavir
US7935817B2 (en) * 2008-03-31 2011-05-03 Apotex Pharmachem Inc. Salt form and cocrystals of adefovir dipivoxil and processes for preparation thereof
AR071318A1 (es) * 2008-04-15 2010-06-09 Basilea Pharmaceutica Ag Benzhidril ester del acido (6r,7r)-7-{2-(5-amino-[1,2,4]tiadiazol-3-il)-2-[(z)-tritiloxiimino]-acetilamino}-3-[(r)-1'-terc-butoxicarbonil-2-oxo-[1,3']bipirrolidinil-(3e)-ilidenometil]-8-oxo-5-tia-1-aza-biciclo[4.2.0]oct-2-eno-2-carboxilico cristalino; su elaboracion y uso
US8097719B2 (en) * 2008-07-15 2012-01-17 Genesen Labs Meropenem intermediate in novel crystalline form and a method of manufacture of meropenem
CN102186854A (zh) * 2008-08-18 2011-09-14 赛诺菲-安万特美国有限责任公司 制备7-氯-N，N，5-三甲基-4-氧代-3-苯基-3，5-二氢-4H-哒嗪并[4，5-b]吲哚-1-乙酰胺的多晶型的方法
AU2011224287B2 (en) 2010-03-12 2015-03-26 Omeros Corporation PDE10 inhibitors and related compositions and methods
WO2012030957A2 (en) * 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
JP2014530805A (ja) * 2011-09-30 2014-11-20 スンシネ ルアケ プハルマ カンパニー リミテッド アジルサルタンの結晶形並びにその製造及び使用
NZ716494A (en) 2014-04-28 2017-07-28 Omeros Corp Processes and intermediates for the preparation of a pde10 inhibitor
NZ630803A (en) * 2014-04-28 2016-03-31 Omeros Corp Optically active pde10 inhibitor
JP2018513153A (ja) 2015-04-24 2018-05-24 オメロス コーポレーション Ｐｄｅ１０インヒビターならびに関連する組成物および方法
WO2017079678A1 (en) 2015-11-04 2017-05-11 Omeros Corporation Solid state forms of a pde10 inhibitor
EP3870292A4 (en) 2018-10-26 2022-11-09 The Research Foundation for The State University of New York COMBINATION OF SEROTONIN-SPECIFIC RESUPPUT INHIBITOR AND SEROTONIN 1A RECEPTOR PARTIAL AGONIST TO REDUCE L-DOPA-INDUCED DYSKINESIA
CN111303230B (zh) * 2020-03-09 2021-07-13 中国食品药品检定研究院 一种黄体酮共晶物及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2766823B1 (fr) * 1997-07-30 1999-10-08 Synthelabo Derives de 4-oxo-3,5-dihydro-4h-pyridazino[4,5-b] indole-1-acetamide, leur preparation et leur application en therapeutique
FR2788696B1 (fr) * 1999-01-26 2004-03-05 Synthelabo Utilisation de derives de pyridazino [4,5-b] indole-1-acetamide pour la preparation de medicaments destines aux maladies du systeme nerveux central
FR2829939B3 (fr) 2001-09-21 2003-11-28 Sanofi Synthelabo Utilisation du 7-chloro-n,n,5-trimethyl-4-oxo-3-phenyl-3,5- dihydro-4h-pyridazino(4,5-b)indole-1-acetamide pour la preparation de medicaments destines au traitement de la polyarthrite rhumatoide
WO2005034999A2 (en) 2003-10-10 2005-04-21 Bvm Holding Co. Composition comprising association complex of a pharmaceutical and a poloxamer

Also Published As

Publication number Publication date
TW200813060A (en) 2008-03-16
US20080139569A1 (en) 2008-06-12
EA014164B1 (ru) 2010-10-29
SI1924585T1 (sl) 2012-09-28
RS52318B (sr) 2012-12-31
CN101253176A (zh) 2008-08-27
CA2619284A1 (en) 2007-03-08
US7683062B2 (en) 2010-03-23
KR20080050577A (ko) 2008-06-09
EA200800716A1 (ru) 2008-08-29
NO20081365L (no) 2008-04-03
AR057099A1 (es) 2007-11-14
DK1924585T3 (da) 2012-02-27
AU2006285142B2 (en) 2012-06-14
HK1123794A1 (en) 2009-06-26
CY1112317T1 (el) 2015-12-09
AU2006285142A1 (en) 2007-03-08
MA30000B1 (fr) 2008-12-01
KR20130087059A (ko) 2013-08-05
CN101253176B (zh) 2012-04-18
ES2375841T3 (es) 2012-03-06
WO2007027525A1 (en) 2007-03-08
CA2619284C (en) 2014-04-29
UA91716C2 (ru) 2010-08-25
JP2009506116A (ja) 2009-02-12
ECSP088209A (es) 2008-06-30
ATE531717T1 (de) 2011-11-15
IL189276A (en) 2012-07-31
PT1924585E (pt) 2012-01-19
IL189276A0 (en) 2008-08-07
NZ566087A (en) 2011-03-31
JP5063600B2 (ja) 2012-10-31
PL1924585T3 (pl) 2012-08-31
TNSN08059A1 (en) 2009-07-14
EP1924585B1 (en) 2011-11-02
ZA200801890B (en) 2009-11-25
HRP20120073T1 (hr) 2012-07-31
UY29771A1 (es) 2007-03-30
BRPI0615259A2 (pt) 2011-05-17
EP1924585A1 (en) 2008-05-28

Similar Documents

Publication Publication Date Title
CR9723A (es) Nueva forma cristalina de un derivado de piridazino[4,5-b] indol
CL2008002538A1 (es) Compuestos derivados de indol sustituidos; composicion farmaceutica que los comprende; y su uso para el tratamiento de una infeccion viral
ECSP078055A (es) Formas sólidas cristalinas de tigeciclina y métodos para preparar las mismas
NO20082793L (no) Nye tiofenderivater
NO20076447L (no) Bicykliske derivater som modulatorer av ionekanaler
CL2010001348A1 (es) Compuestos derivados de 1-oxo-2,3-dihidro-1h-isoindolin-5-il)-isoxazol-3-carboxamida, potenciadores de los mglur2; composicion farmaceutica; y su uso para aliviar los sintomas o disminuir la aparicion de los sintomas de ezquizofrenia o ansiedad.
CL2008002539A1 (es) Compuestos derivados de indol sustituidos; composicion farmaceutica que los comprende; y su uso para el tratamiento de una infeccion viral
NO20091395L (no) Nye tiofenderivater
NO20083630L (no) Nye pyridinderivater
CL2007003686A1 (es) Compuestos derivados de indol con anillo unido en las posiciones 4,5; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para tratar una infeccion viral.
AR047928A1 (es) Derivados de tetrahidropiridoindol
NO20074431L (no) Pyrrolopyrimidiner nyttige som proteinkinaseinhibitorer
UY29459A1 (es) Forma cristalina ortorrómbica del maleato de asenapina y su uso en el tratamiento de trastornos mentales
ECSP077296A (es) Fenilaminotiazoles sustituidos y su uso
MY147949A (en) Hydrogenated benzo[c]thiophene derivatives as immunomodulators
ECSP12011935A (es) Triazolopiridinas
CL2008001157A1 (es) Compuestos derivados de quinolina-carboxamida, antagonistas de p2y12; procedimiento de preparacion; composicion farmaceutica que comprende a dicho compuesto; composicion de una combinacion de dichos compuestos; y uso del compuesto en el tratamiento de trastornos cardiovasculares, tromboembolismo, infarto agudo al miocardio.
CL2008002540A1 (es) Compuestos derivados aza-indol-2,3-sustituidos; composicion farmaceutica; y uso ene l tratamiento de una infeccion viral.
NO20071095L (no) Hittil ukjente tiofenderivater
ECSP10010129A (es) Inhibidores de quinasas símil polo
NO20076648L (no) Novel thiophene derivatives
EA200970273A1 (ru) Применение 2-6-(3-аминопиперидин-1-ил)-3-метил-2,4-диоксо-3,4-дигидро-2н-пиримидин-1-илметил-4-фторбензонитрила
CL2009000512A1 (es) Compuestos heterociclicos sustituidos derivados de imidazo[4,5-d]piridazina, imidazo[4,5-c]piridazina, imidazo[4,5d]pirimidina, entre otros; composicion farmaceutica que comprende a dichos comppuestos; y uso para tratar el virus de la hepatitis c.
AR054347A1 (es) Combinaciones terapeuticas para el tratamiento o la prevencion de la depresion
CL2008003659A1 (es) Compuestos derivados de 6-(4-bencilpiperazin-1-il)pirimidin-4-ona, moduladores de la enzima estearoil-coa-desaturasa 1; procedimiento de preparacion; composicin farmaceutica; y uso en el tratamiento y profilaxis de la obesidad.