ATE531717T1 - Neue kristalline form eines pyridazinoä4,5- büindolderivats - Google Patents

Neue kristalline form eines pyridazinoä4,5- büindolderivats

Info

Publication number
ATE531717T1
ATE531717T1 AT06813757T AT06813757T ATE531717T1 AT E531717 T1 ATE531717 T1 AT E531717T1 AT 06813757 T AT06813757 T AT 06813757T AT 06813757 T AT06813757 T AT 06813757T AT E531717 T1 ATE531717 T1 AT E531717T1
Authority
AT
Austria
Prior art keywords
büindol
derivative
crystalline form
new crystalline
new
Prior art date
Application number
AT06813757T
Other languages
English (en)
Inventor
William Rocco
John Higgins
Original Assignee
Sanofi Aventis Us Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37546937&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE531717(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis Us Llc filed Critical Sanofi Aventis Us Llc
Application granted granted Critical
Publication of ATE531717T1 publication Critical patent/ATE531717T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT06813757T 2005-08-29 2006-08-24 Neue kristalline form eines pyridazinoä4,5- büindolderivats ATE531717T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71215305P 2005-08-29 2005-08-29
PCT/US2006/033254 WO2007027525A1 (en) 2005-08-29 2006-08-24 Novel crystalline form of a pyridazino [4 , 5-b] indole derivative

Publications (1)

Publication Number Publication Date
ATE531717T1 true ATE531717T1 (de) 2011-11-15

Family

ID=37546937

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06813757T ATE531717T1 (de) 2005-08-29 2006-08-24 Neue kristalline form eines pyridazinoä4,5- büindolderivats

Country Status (31)

Country Link
US (1) US7683062B2 (de)
EP (1) EP1924585B1 (de)
JP (1) JP5063600B2 (de)
KR (2) KR20130087059A (de)
CN (1) CN101253176B (de)
AR (1) AR057099A1 (de)
AT (1) ATE531717T1 (de)
AU (1) AU2006285142B2 (de)
BR (1) BRPI0615259A2 (de)
CA (1) CA2619284C (de)
CR (1) CR9723A (de)
CY (1) CY1112317T1 (de)
DK (1) DK1924585T3 (de)
EA (1) EA014164B1 (de)
EC (1) ECSP088209A (de)
ES (1) ES2375841T3 (de)
HR (1) HRP20120073T1 (de)
IL (1) IL189276A (de)
MA (1) MA30000B1 (de)
NO (1) NO20081365L (de)
NZ (1) NZ566087A (de)
PL (1) PL1924585T3 (de)
PT (1) PT1924585E (de)
RS (1) RS52318B (de)
SI (1) SI1924585T1 (de)
TN (1) TNSN08059A1 (de)
TW (1) TW200813060A (de)
UA (1) UA91716C2 (de)
UY (1) UY29771A1 (de)
WO (1) WO2007027525A1 (de)
ZA (1) ZA200801890B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2678125C (en) * 2003-11-17 2014-10-14 Merck Eprova Ag Crystalline forms of (6r)-l-erythro-tetrahydrobiopterin dihydrochloride
ES2370829T3 (es) * 2004-06-02 2011-12-23 Sandoz Ag Producto intermedio de meropenem en forma cristalina.
AU2006298881A1 (en) * 2005-09-21 2007-04-12 4Sc Ag Sulphonylpyrrole hydrochloride salts as histone deacetylases inhibitors
NZ567357A (en) * 2005-10-31 2011-05-27 Janssen Pharmaceutica Nv Novel processes for the preparation of piperazinyl and diazapanyl benzamide derivatives
CA2656057C (en) * 2006-06-16 2012-10-02 H. Lundbeck A/S Crystalline forms of 4-[2-(4-methylphenylsulfanyl)-phenyl]piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain
KR20090084891A (ko) * 2006-10-27 2009-08-05 시그날 파마소티칼 엘엘씨 4-[9-(테트라하이드로-퓨란-3-일)-8-(2,4,6-트리플루오로-페닐아미노)-9ｈ-퓨린-2-일아미노]-사이클로헥산-1-올을 포함하는 고체 형태들, 이들의 조성물들 및 이들의 용도
EP2085397A1 (de) * 2008-01-21 2009-08-05 Esteve Quimica, S.A. Kristalline Form von Abacavir
US7935817B2 (en) * 2008-03-31 2011-05-03 Apotex Pharmachem Inc. Salt form and cocrystals of adefovir dipivoxil and processes for preparation thereof
AR071318A1 (es) * 2008-04-15 2010-06-09 Basilea Pharmaceutica Ag Benzhidril ester del acido (6r,7r)-7-{2-(5-amino-[1,2,4]tiadiazol-3-il)-2-[(z)-tritiloxiimino]-acetilamino}-3-[(r)-1'-terc-butoxicarbonil-2-oxo-[1,3']bipirrolidinil-(3e)-ilidenometil]-8-oxo-5-tia-1-aza-biciclo[4.2.0]oct-2-eno-2-carboxilico cristalino; su elaboracion y uso
US8097719B2 (en) * 2008-07-15 2012-01-17 Genesen Labs Meropenem intermediate in novel crystalline form and a method of manufacture of meropenem
CN102186854A (zh) * 2008-08-18 2011-09-14 赛诺菲-安万特美国有限责任公司 制备7-氯-N，N，5-三甲基-4-氧代-3-苯基-3，5-二氢-4H-哒嗪并[4，5-b]吲哚-1-乙酰胺的多晶型的方法
AU2011224287B2 (en) 2010-03-12 2015-03-26 Omeros Corporation PDE10 inhibitors and related compositions and methods
WO2012030957A2 (en) * 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
JP2014530805A (ja) * 2011-09-30 2014-11-20 スンシネ ルアケ プハルマ カンパニー リミテッド アジルサルタンの結晶形並びにその製造及び使用
NZ716494A (en) 2014-04-28 2017-07-28 Omeros Corp Processes and intermediates for the preparation of a pde10 inhibitor
NZ630803A (en) * 2014-04-28 2016-03-31 Omeros Corp Optically active pde10 inhibitor
JP2018513153A (ja) 2015-04-24 2018-05-24 オメロス コーポレーション Ｐｄｅ１０インヒビターならびに関連する組成物および方法
WO2017079678A1 (en) 2015-11-04 2017-05-11 Omeros Corporation Solid state forms of a pde10 inhibitor
EP3870292A4 (de) 2018-10-26 2022-11-09 The Research Foundation for The State University of New York Kombination von serotonin-spezifischem wiederaufnahmeinhibitor und serotonin-1a-rezeptor-partialagonist zur verminderung von l-dopa-induzierter dyskinesie
CN111303230B (zh) * 2020-03-09 2021-07-13 中国食品药品检定研究院 一种黄体酮共晶物及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2766823B1 (fr) * 1997-07-30 1999-10-08 Synthelabo Derives de 4-oxo-3,5-dihydro-4h-pyridazino[4,5-b] indole-1-acetamide, leur preparation et leur application en therapeutique
FR2788696B1 (fr) * 1999-01-26 2004-03-05 Synthelabo Utilisation de derives de pyridazino [4,5-b] indole-1-acetamide pour la preparation de medicaments destines aux maladies du systeme nerveux central
FR2829939B3 (fr) 2001-09-21 2003-11-28 Sanofi Synthelabo Utilisation du 7-chloro-n,n,5-trimethyl-4-oxo-3-phenyl-3,5- dihydro-4h-pyridazino(4,5-b)indole-1-acetamide pour la preparation de medicaments destines au traitement de la polyarthrite rhumatoide
WO2005034999A2 (en) 2003-10-10 2005-04-21 Bvm Holding Co. Composition comprising association complex of a pharmaceutical and a poloxamer

Also Published As

Publication number Publication date
TW200813060A (en) 2008-03-16
US20080139569A1 (en) 2008-06-12
EA014164B1 (ru) 2010-10-29
SI1924585T1 (sl) 2012-09-28
RS52318B (sr) 2012-12-31
CN101253176A (zh) 2008-08-27
CA2619284A1 (en) 2007-03-08
US7683062B2 (en) 2010-03-23
KR20080050577A (ko) 2008-06-09
EA200800716A1 (ru) 2008-08-29
NO20081365L (no) 2008-04-03
AR057099A1 (es) 2007-11-14
DK1924585T3 (da) 2012-02-27
AU2006285142B2 (en) 2012-06-14
HK1123794A1 (en) 2009-06-26
CY1112317T1 (el) 2015-12-09
AU2006285142A1 (en) 2007-03-08
CR9723A (es) 2008-06-18
MA30000B1 (fr) 2008-12-01
KR20130087059A (ko) 2013-08-05
CN101253176B (zh) 2012-04-18
ES2375841T3 (es) 2012-03-06
WO2007027525A1 (en) 2007-03-08
CA2619284C (en) 2014-04-29
UA91716C2 (ru) 2010-08-25
JP2009506116A (ja) 2009-02-12
ECSP088209A (es) 2008-06-30
IL189276A (en) 2012-07-31
PT1924585E (pt) 2012-01-19
IL189276A0 (en) 2008-08-07
NZ566087A (en) 2011-03-31
JP5063600B2 (ja) 2012-10-31
PL1924585T3 (pl) 2012-08-31
TNSN08059A1 (en) 2009-07-14
EP1924585B1 (de) 2011-11-02
ZA200801890B (en) 2009-11-25
HRP20120073T1 (hr) 2012-07-31
UY29771A1 (es) 2007-03-30
BRPI0615259A2 (pt) 2011-05-17
EP1924585A1 (de) 2008-05-28

Similar Documents

Publication Publication Date Title
ATE531717T1 (de) Neue kristalline form eines pyridazinoä4,5- büindolderivats
HUS1900034I1 (hu) 6,7-telítetlen-7-karbamoil-szubsztituált morfinán-származékok
DK1902037T3 (da) 2,4-diamino-pyrimidiner som auroainhibitorer
ATE481383T1 (de) 3-aza-bicycloä3.1.0ühexanderivate
ATE502012T1 (de) 1,1,1-trifluor-2-hydroxy-3-phenylpropan-derivat
HRP20120323T1 (en) Diarylhydantoin compounds
DE602005005306D1 (de) Steuerung der Bahn eines Greifers
EP1935890A4 (de) 2-heteroarylsubstituiertes indolderivat
DE602007001681D1 (de) 1,3-dioxan-carboxylsäuren
DK3275965T3 (da) Sammensætninger, der omfatter en fluorolefin
BRPI0815059A2 (pt) Derivado de 1,3-di-hidroisoindol
DE602006005030D1 (de) Phasenaustauschtinten
ATE487691T1 (de) Acetylenderivate
NL2000937A1 (nl) Piperidinederivaten.
EP1870401A4 (de) 1,4-substituiertes piperazinderivat
ATE425167T1 (de) Neue pyridothienopyrimidinderivate
NL1032046A1 (nl) Prostaglandinederivaten.
DK1963295T3 (da) 3,6-dihydro-2-oxo-6H-(1,3,4)thiazinderivater
ATE445604T1 (de) Neue 2,6-diaminopyridin-3-on-derivate
TWI315670B (en) Substituted aryl 1,4-pyrazine derivatives
BRPI0818848A2 (pt) Compostos de 2,3-di-idro-benzofurano
NL1032323A1 (nl) Klep.
DK2010514T3 (da) 3-(pyridin-2-yl)-[1,2,4]-triaziner som fungicider
ITMO20050015A1 (it) 'essiccatoio a spruzzo perfezionato.
DE602006008015D1 (de) Feste salzformen eines pyrrolsubstituierten 2-indolinons