DK1924585T3 - Hidtil ukendt krystallinsk for af et pyridazino[4,5-b]indol-derivat - Google Patents

Hidtil ukendt krystallinsk for af et pyridazino[4,5-b]indol-derivat

Info

Publication number
DK1924585T3
DK1924585T3 DK06813757.9T DK06813757T DK1924585T3 DK 1924585 T3 DK1924585 T3 DK 1924585T3 DK 06813757 T DK06813757 T DK 06813757T DK 1924585 T3 DK1924585 T3 DK 1924585T3
Authority
DK
Denmark
Prior art keywords
pyridazino
hitherto
lining
crystalline
indole derivative
Prior art date
Application number
DK06813757.9T
Other languages
English (en)
Inventor
William L Rocco
John D Higgins
Original Assignee
Sanofi Aventis Us Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37546937&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1924585(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis Us Llc filed Critical Sanofi Aventis Us Llc
Application granted granted Critical
Publication of DK1924585T3 publication Critical patent/DK1924585T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK06813757.9T 2005-08-29 2006-08-24 Hidtil ukendt krystallinsk for af et pyridazino[4,5-b]indol-derivat DK1924585T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71215305P 2005-08-29 2005-08-29
PCT/US2006/033254 WO2007027525A1 (en) 2005-08-29 2006-08-24 Novel crystalline form of a pyridazino [4 , 5-b] indole derivative

Publications (1)

Publication Number Publication Date
DK1924585T3 true DK1924585T3 (da) 2012-02-27

Family

ID=37546937

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06813757.9T DK1924585T3 (da) 2005-08-29 2006-08-24 Hidtil ukendt krystallinsk for af et pyridazino[4,5-b]indol-derivat

Country Status (31)

Country Link
US (1) US7683062B2 (da)
EP (1) EP1924585B1 (da)
JP (1) JP5063600B2 (da)
KR (2) KR20130087059A (da)
CN (1) CN101253176B (da)
AR (1) AR057099A1 (da)
AT (1) ATE531717T1 (da)
AU (1) AU2006285142B2 (da)
BR (1) BRPI0615259A2 (da)
CA (1) CA2619284C (da)
CR (1) CR9723A (da)
CY (1) CY1112317T1 (da)
DK (1) DK1924585T3 (da)
EA (1) EA014164B1 (da)
EC (1) ECSP088209A (da)
ES (1) ES2375841T3 (da)
HR (1) HRP20120073T1 (da)
IL (1) IL189276A (da)
MA (1) MA30000B1 (da)
NO (1) NO20081365L (da)
NZ (1) NZ566087A (da)
PL (1) PL1924585T3 (da)
PT (1) PT1924585E (da)
RS (1) RS52318B (da)
SI (1) SI1924585T1 (da)
TN (1) TNSN08059A1 (da)
TW (1) TW200813060A (da)
UA (1) UA91716C2 (da)
UY (1) UY29771A1 (da)
WO (1) WO2007027525A1 (da)
ZA (1) ZA200801890B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2678125C (en) * 2003-11-17 2014-10-14 Merck Eprova Ag Crystalline forms of (6r)-l-erythro-tetrahydrobiopterin dihydrochloride
JP2008501657A (ja) * 2004-06-02 2008-01-24 サンド・アクチエンゲゼルシヤフト 結晶形態のメロペネム中間体
CN101287706A (zh) * 2005-09-21 2008-10-15 尼科梅德有限责任公司 作为组蛋白脱乙酰基酶抑制剂的磺酰基吡咯盐酸盐
US7728129B2 (en) * 2005-10-31 2010-06-01 Janssen Pharmaceutica Nv Processes for the preparation of piperazinyl and diazapanyl benzamide derivatives
AU2007260356B2 (en) * 2006-06-16 2013-01-24 H. Lundbeck A/S Crystalline forms of 4- [2- (4-methylphenylsulfanyl) -phenyl] piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain
NZ598071A (en) * 2006-10-27 2013-08-30 Signal Pharm Llc Uses of and pharmaceutical compositions comprising 4-[9-(tetrahydro-furan-3-yl)-8-(2,4,6-trifluoro-phenylamino)-9h-purin-2-ylamino]-cyclohexan-1-ol compounds
EP2085397A1 (en) * 2008-01-21 2009-08-05 Esteve Quimica, S.A. Crystalline form of abacavir
US7935817B2 (en) * 2008-03-31 2011-05-03 Apotex Pharmachem Inc. Salt form and cocrystals of adefovir dipivoxil and processes for preparation thereof
AR071318A1 (es) * 2008-04-15 2010-06-09 Basilea Pharmaceutica Ag Benzhidril ester del acido (6r,7r)-7-{2-(5-amino-[1,2,4]tiadiazol-3-il)-2-[(z)-tritiloxiimino]-acetilamino}-3-[(r)-1'-terc-butoxicarbonil-2-oxo-[1,3']bipirrolidinil-(3e)-ilidenometil]-8-oxo-5-tia-1-aza-biciclo[4.2.0]oct-2-eno-2-carboxilico cristalino; su elaboracion y uso
US8097719B2 (en) * 2008-07-15 2012-01-17 Genesen Labs Meropenem intermediate in novel crystalline form and a method of manufacture of meropenem
RU2011110241A (ru) * 2008-08-18 2012-09-27 САНОФИ-АВЕНТИС Ю.Эс. ЭлЭлСи (US) СПОСОБ ПОЛУЧЕНИЯ ПОЛИМОРФА 7-ХЛОР-N,N,5-ТРИМЕТИЛ-4-ОКСО-3-ФЕНИЛ-3,5-ДИГИДРО-4Н-ПИРИДАЗИНО[4,5-b]ИНДОЛ-1-АЦЕТАМИДА
PT2544679T (pt) 2010-03-12 2019-07-11 Omeros Corp Inibidores de pde-10 e composições e métodos relacionados
JP2013536859A (ja) * 2010-09-01 2013-09-26 アリーナ ファーマシューティカルズ， インコーポレイテッド ５−ｈｔ２ｃアゴニストの非吸湿性塩
JP2014530805A (ja) * 2011-09-30 2014-11-20 スンシネ ルアケ プハルマ カンパニー リミテッド アジルサルタンの結晶形並びにその製造及び使用
NZ630803A (en) * 2014-04-28 2016-03-31 Omeros Corp Optically active pde10 inhibitor
NZ716494A (en) 2014-04-28 2017-07-28 Omeros Corp Processes and intermediates for the preparation of a pde10 inhibitor
US9879002B2 (en) 2015-04-24 2018-01-30 Omeros Corporation PDE10 inhibitors and related compositions and methods
US9920045B2 (en) 2015-11-04 2018-03-20 Omeros Corporation Solid state forms of a PDE10 inhibitor
US20210393621A1 (en) 2018-10-26 2021-12-23 The Research Foundation For The State University Of New York Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia
CN111303230B (zh) * 2020-03-09 2021-07-13 中国食品药品检定研究院 一种黄体酮共晶物及其制备方法和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2766823B1 (fr) 1997-07-30 1999-10-08 Synthelabo Derives de 4-oxo-3,5-dihydro-4h-pyridazino[4,5-b] indole-1-acetamide, leur preparation et leur application en therapeutique
FR2788696B1 (fr) * 1999-01-26 2004-03-05 Synthelabo Utilisation de derives de pyridazino [4,5-b] indole-1-acetamide pour la preparation de medicaments destines aux maladies du systeme nerveux central
FR2829939B3 (fr) 2001-09-21 2003-11-28 Sanofi Synthelabo Utilisation du 7-chloro-n,n,5-trimethyl-4-oxo-3-phenyl-3,5- dihydro-4h-pyridazino(4,5-b)indole-1-acetamide pour la preparation de medicaments destines au traitement de la polyarthrite rhumatoide
WO2005034999A2 (en) 2003-10-10 2005-04-21 Bvm Holding Co. Composition comprising association complex of a pharmaceutical and a poloxamer

Also Published As

Publication number Publication date
IL189276A0 (en) 2008-08-07
AU2006285142B2 (en) 2012-06-14
CY1112317T1 (el) 2015-12-09
NZ566087A (en) 2011-03-31
TNSN08059A1 (en) 2009-07-14
HK1123794A1 (en) 2009-06-26
UA91716C2 (ru) 2010-08-25
RS52318B (sr) 2012-12-31
JP5063600B2 (ja) 2012-10-31
SI1924585T1 (sl) 2012-09-28
CA2619284A1 (en) 2007-03-08
EP1924585B1 (en) 2011-11-02
EP1924585A1 (en) 2008-05-28
MA30000B1 (fr) 2008-12-01
BRPI0615259A2 (pt) 2011-05-17
PT1924585E (pt) 2012-01-19
NO20081365L (no) 2008-04-03
PL1924585T3 (pl) 2012-08-31
IL189276A (en) 2012-07-31
TW200813060A (en) 2008-03-16
EA014164B1 (ru) 2010-10-29
US7683062B2 (en) 2010-03-23
CA2619284C (en) 2014-04-29
HRP20120073T1 (hr) 2012-07-31
ES2375841T3 (es) 2012-03-06
KR20080050577A (ko) 2008-06-09
KR20130087059A (ko) 2013-08-05
CN101253176A (zh) 2008-08-27
WO2007027525A1 (en) 2007-03-08
JP2009506116A (ja) 2009-02-12
EA200800716A1 (ru) 2008-08-29
CR9723A (es) 2008-06-18
ZA200801890B (en) 2009-11-25
AU2006285142A1 (en) 2007-03-08
ATE531717T1 (de) 2011-11-15
ECSP088209A (es) 2008-06-30
AR057099A1 (es) 2007-11-14
CN101253176B (zh) 2012-04-18
US20080139569A1 (en) 2008-06-12
UY29771A1 (es) 2007-03-30

Similar Documents

Publication Publication Date Title
DK1924585T3 (da) Hidtil ukendt krystallinsk for af et pyridazino[4,5-b]indol-derivat
DK1924151T3 (da) Oral frigivelsessystem med styret frigivelse
EP1958592A4 (en) intraocular lens
MA28548B1 (fr) Composes macrocycliques inhibiteurs de replication virale
DK1883451T3 (da) Substituerede indolforbindelser med NOS-hæmmende virkning
ZA200609225B (en) Indole derivatives having piperidine rings
DK1863833T3 (da) Fremgangsmåde til fremstilling af makrocykliske forbindelser
ATE501119T1 (de) Entzündungshemmende indol-derivate
PL2067108T3 (pl) Lokalizowanie węzłów odniesienia do pozycjonowania
HUS1200009I1 (hu) Pirrolo[2,3-B]piridin származékok, mint protein kináz inhibitorok
GB0419481D0 (en) Isoindolin-1-one derivatives
DK1710241T3 (da) Intermediatforbindelser til fremstilling af trans-5-chlor-2-methyl-2,3,3a,12b-tetrahydro-1h-dibenz[2,3:6,7]oxepino[4,5-c]pyrrol
BRPI0716554A2 (pt) compostos de mÉtodos para agentes rotulados de 18f
DK1838683T3 (da) Fremgangsmåde til fremstilling af [1,4,5]-oxadiazepinderivater
GB0405334D0 (en) Method for exchanging signals via nodes
EP1893625A4 (en) PROCESS FOR THE PREPARATION OF 9-DEAZAPURINE DERIVATIVES
DK1682541T3 (da) Fremgangsmåde til fremstilling af tiotropiumsalte
DK1784183T3 (da) Fremgangsmåder til fremstilling af isothiazolderivater
DK2220082T3 (da) Stabilt krystallinsk salt af (R)-3-fluorphenyl-3,4,5-trifluorbenzylcarbaminsyre-1-azabicyclo[2.2.2]oct-3-ylester
EP2170329A4 (en) CRYSTALLINE POLYMORPH OF 7-ETHYL-10-HYDROXYCAMPTOTHECIN
EP1847546A4 (en) imidazopyridine derivative
ZA200706292B (en) Novel salts of 6-heterocyclyl substituted hexahydrophenanthridine derivatives
DK1888613T3 (da) Fremgangsmåde til fremstilling af thiophenglycosidderivater
ATE489386T1 (de) Naphthyridin-derivate
IL191546A0 (en) Process for the preparation of purified crystalline cci-779