CS243570B1 - Omega-aryloxoalkane acids - Google Patents

Omega-aryloxoalkane acids Download PDF

Info

Publication number
CS243570B1
CS243570B1 CS846586A CS658684A CS243570B1 CS 243570 B1 CS243570 B1 CS 243570B1 CS 846586 A CS846586 A CS 846586A CS 658684 A CS658684 A CS 658684A CS 243570 B1 CS243570 B1 CS 243570B1
Authority
CS
Czechoslovakia
Prior art keywords
acid
methyl
mol
crystallization
filtered
Prior art date
Application number
CS846586A
Other languages
Czech (cs)
English (en)
Other versions
CS658684A1 (en
Inventor
Miroslav Kuchar
Bohumila Brunova
Jaroslava Grimova
Eva Maturova
Original Assignee
Miroslav Kuchar
Bohumila Brunova
Jaroslava Grimova
Eva Maturova
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miroslav Kuchar, Bohumila Brunova, Jaroslava Grimova, Eva Maturova filed Critical Miroslav Kuchar
Priority to CS846586A priority Critical patent/CS243570B1/cs
Priority to EP85304071A priority patent/EP0180290B1/de
Priority to AT85304071T priority patent/ATE30412T1/de
Priority to CA000485594A priority patent/CA1238342A/en
Priority to US06/760,338 priority patent/US4683331A/en
Publication of CS658684A1 publication Critical patent/CS658684A1/cs
Priority to JP60187535A priority patent/JPH0641433B2/ja
Priority to FI853318A priority patent/FI853318A7/fi
Publication of CS243570B1 publication Critical patent/CS243570B1/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/88—Unsaturated compounds containing keto groups containing halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
CS846586A 1984-08-31 1984-08-31 Omega-aryloxoalkane acids CS243570B1 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CS846586A CS243570B1 (en) 1984-08-31 1984-08-31 Omega-aryloxoalkane acids
EP85304071A EP0180290B1 (de) 1984-08-31 1985-06-10 Omega-(2',4'-Dihalogenphenylyl)oxoalkansäuren und Verfahren zu ihrer Herstellung
AT85304071T ATE30412T1 (de) 1984-08-31 1985-06-10 Omega-(2',4'-dihalogenphenylyl)oxoalkansaeuren und verfahren zu ihrer herstellung.
CA000485594A CA1238342A (en) 1984-08-31 1985-06-27 Omega-/2,4-dihalobiphenylyl/oxo alkanoic acids and a process for their preparation
US06/760,338 US4683331A (en) 1984-08-31 1985-07-29 Omega-(2,4-dihalobiphenylyl) oxo alkanoic acids
JP60187535A JPH0641433B2 (ja) 1984-08-31 1985-08-28 ω‐（２’，４’‐ジハロビフエニイル）オキソアルカン酸およびその製法
FI853318A FI853318A7 (fi) 1984-08-31 1985-08-29 Omega-(2',4'-dihalobifenylyyli) oksoalkaanihapot ja menetelmä niiden valmistamiseksi.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS846586A CS243570B1 (en) 1984-08-31 1984-08-31 Omega-aryloxoalkane acids

Publications (2)

Publication Number Publication Date
CS658684A1 CS658684A1 (en) 1985-08-15
CS243570B1 true CS243570B1 (en) 1986-06-12

Family

ID=5413269

Family Applications (1)

Application Number Title Priority Date Filing Date
CS846586A CS243570B1 (en) 1984-08-31 1984-08-31 Omega-aryloxoalkane acids

Country Status (7)

Country Link
US (1) US4683331A (de)
EP (1) EP0180290B1 (de)
JP (1) JPH0641433B2 (de)
AT (1) ATE30412T1 (de)
CA (1) CA1238342A (de)
CS (1) CS243570B1 (de)
FI (1) FI853318A7 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS276833B6 (en) * 1990-06-18 1992-08-12 Vyzk Ustav Farm Biochem Sp Functional derivatives of 4-(2,4-difluorobiphenylyl)-2-methyl -4- oxobutanoic acid
HRP950558A2 (en) * 1994-11-15 1997-12-31 Scott M. Wilhelm Substituted 4-biarylbutric or biarylpentanoic acids and derivatives as matrix metalloprotease inhibitors
US5789434A (en) * 1994-11-15 1998-08-04 Bayer Corporation Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors
US5886022A (en) * 1995-06-05 1999-03-23 Bayer Corporation Substituted cycloalkanecarboxylic acid derivatives as matrix metalloprotease inhibitors
TNSN97081A1 (fr) * 1996-05-15 2005-03-15 Bayer Corp Inhibition des matrices metalloproteinases par 2- (w-aroylkyl) -4-biaryl-4-des acides oxubutyriques
US5932763A (en) * 1997-05-15 1999-08-03 Bayer Corporation Inhibition of matrix metalloproteases by 2-(ω-arolalkyl)-4-biaryl-4-oxobutyric acids
DE10047118A1 (de) * 2000-09-22 2002-04-11 Bayer Ag Verfahren zur Herstellung von Ketocarbonsäurederivaten

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA592074A (en) * 1960-02-02 Shaw Bernard Method of reshaping cylindrical glass tubes
US3182061A (en) * 1961-03-20 1965-05-04 Warner Lambert Pharmaceutical 5-[4-(p-hydroxyphenoxy)phenyl]-5-oxo-3-methylvaleric acid
DE2112716A1 (de) * 1971-03-17 1972-10-05 Thomae Gmbh Dr K Neue 4-(4-Biphenylyl)-4-oxobuttersaeuren,ihre Salze und ihre Ester
NL7203400A (de) * 1971-03-17 1972-09-19
FR2378741A1 (fr) * 1977-02-01 1978-08-25 Fabre Sa Pierre Acides garyl goxo isovaleriques doues de proprietes antiphlogistiques et antalgiques

Also Published As

Publication number Publication date
JPH0641433B2 (ja) 1994-06-01
EP0180290A1 (de) 1986-05-07
US4683331A (en) 1987-07-28
FI853318A0 (fi) 1985-08-29
CA1238342A (en) 1988-06-21
EP0180290B1 (de) 1987-10-28
CS658684A1 (en) 1985-08-15
FI853318L (fi) 1986-03-01
JPS6165842A (ja) 1986-04-04
FI853318A7 (fi) 1986-03-01
ATE30412T1 (de) 1987-11-15

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